{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T13:37:52Z","timestamp":1773495472658,"version":"3.50.1"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T00:00:00Z","timestamp":1524096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0196149","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T17:43:17Z","timestamp":1524159797000},"page":"e0196149","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":8,"title":["Anatomical distribution of cerebral microbleeds and intracerebral hemorrhage in vertebrobasilar dolichoectasia"],"prefix":"10.1371","volume":"13","author":[{"given":"Alex","family":"F\u00f6rster","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf","family":"Wenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1t\u00e9 El\u00f6d","family":"Maros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"B\u00f6hme","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansour","family":"Al-Zghloul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelika","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Groden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3463-5093","authenticated-orcid":true,"given":"Holger","family":"Wenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,4,19]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1749-6632.2009.05114.x","article-title":"Vertebrobasilar dilatative arteriopathy (dolichoectasia)","volume":"1184","author":"M Lou","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1159\/000007991","article-title":"Dolicho-vertebrobasilar abnormality and migraine-like attacks","volume":"41","author":"CA Zambrino","year":"1999","journal-title":"Eur Neurol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1053\/jscd.2000.7224","article-title":"Vertebrobasilar dolichoectasia associated with Marfan syndrome","volume":"9","author":"IE Silverman","year":"2000","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1681\/ASN.V881298","article-title":"Intracranial arterial dolichoectasia in autosomal dominant polycystic kidney disease","volume":"8","author":"WI Schievink","year":"1997","journal-title":"J Am Soc Nephrol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/ndt\/17.5.819","article-title":"Intracranial aneurysms and dolichoectasia in autosomal dominant polycystic kidney disease","volume":"17","author":"S Graf","year":"2002","journal-title":"Nephrol Dial Transplant"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/brain\/awh546","article-title":"Megadolichobasilar anomaly with thrombosis in a family with Fabry\u2019s disease and a novel mutation in the alpha-galactosidase A gene","volume":"128","author":"F Garzuly","year":"2005","journal-title":"Brain"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/ana.410400105","article-title":"Cerebrovascular complications of Fabry\u2019s disease","volume":"40","author":"P Mitsias","year":"1996","journal-title":"Ann Neurol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.5414\/NPP27037","article-title":"Giant serpentine aneurysm of vertebrobasilar artery mimicking dolichoectasia\u2014an unusual complication of pediatric AIDS. Report of a case with review of the literature","volume":"27","author":"A Mahadevan","journal-title":"Clin Neuropathol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1007\/s00115-007-2263-7","article-title":"Type I neurofibromatosis and megadolichobasilar artery","volume":"78","author":"C Roth","year":"2007","journal-title":"Nervenarzt"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.jocn.2011.05.033","article-title":"Hemifacial spasm, vertebrobasilar dolichoectasia and neurofibromatosis type 1","volume":"19","author":"E de Pablo-Fern\u00e1ndez","year":"2012","journal-title":"J Clin Neurosci"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1212\/01.WNL.0000103168.14885.A8","article-title":"Intracranial arterial dolichoectasia and its relation with atherosclerosis and stroke subtype","volume":"61","author":"F Pico","year":"2003","journal-title":"Neurology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/S1474-4422(15)00089-7","article-title":"Pathophysiology, presentation, prognosis, and management of intracranial arterial dolichoectasia","volume":"14","author":"F Pico","year":"2015","journal-title":"Lancet Neurol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1212\/WNL.39.1.16","article-title":"Stroke in patients with fusiform vertebrobasilar aneurysms","volume":"39","author":"MS Pessin","year":"1989","journal-title":"Neurology"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/S1388-2457(01)00597-1","article-title":"Brain-stem compression in vertebrobasilar dolichoectasia. A multimodal electrophysiological study","volume":"112","author":"S Passero","year":"2001","journal-title":"Clin Neurophysiol"},{"key":"ref15","first-page":"22","article-title":"Vertebrobasilar dolichoectasia diagnosed by magnetic resonance angiography and risk of stroke and death: a cohort study","volume":"75","author":"EE Ubogu","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1161\/01.STR.0000172311.64662.9c","article-title":"Intracranial bleeding in patients with vertebrobasilar dolichoectasia","volume":"36","author":"SG Passero","year":"2005","journal-title":"Stroke"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1212\/01.wnl.0000286947.89193.f3","article-title":"Natural history of vertebrobasilar dolichoectasia","volume":"70","author":"SG Passero","year":"2008","journal-title":"Neurology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/ene.12075","article-title":"Vertebrobasilar dolichoectasia as a risk factor for cerebral microbleeds","volume":"20","author":"J-M Park","year":"2013","journal-title":"Eur J Neurol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1474-4422(09)70013-4","article-title":"Cerebral microbleeds: a guide to detection and interpretation","volume":"8","author":"SM Greenberg","year":"2009","journal-title":"Lancet Neurol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.jocn.2012.12.002","article-title":"Associations and implications of cerebral microbleeds","volume":"20","author":"TJ Kleinig","year":"2013","journal-title":"J Clin Neurosci"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.5853\/jos.2013.15.3.153","article-title":"Cerebral microbleeds: their associated factors, radiologic findings, and clinical implications","volume":"15","author":"BJ Kim","year":"2013","journal-title":"J stroke"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3389\/fneur.2013.00205","article-title":"Cerebral Microbleeds: A Review of Clinical, Genetic, and Neuroimaging Associations","volume":"4","author":"PA Yates","year":"2014","journal-title":"Front Neurol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s10278-004-1014-6","article-title":"OsiriX: an open-source software for navigating in multidimensional DICOM images","volume":"17","author":"A Rosset","year":"2004","journal-title":"J Digit Imaging"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/BF00339693","article-title":"Vertebrobasilar dolichoectasia: assessment using MR","volume":"30","author":"DW Giang","year":"1988","journal-title":"Neuroradiology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00062-013-0261-7","article-title":"A comparison of CT\/CT angiography and MRI\/MR angiography for imaging of vertebrobasilar dolichoectasia","volume":"24","author":"A F\u00f6rster","year":"2014","journal-title":"Clin Neuroradiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/jon.12177","article-title":"Fluid Attenuated Inversion Recovery Vascular Hyperintensities Possibly Indicate Slow Arterial Blood Flow in Vertebrobasilar Dolichoectasia","volume":"25","author":"A F\u00f6rster","year":"2015","journal-title":"J Neuroimaging"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"915","DOI":"10.3174\/ajnr.A5102","article-title":"Clinical and Imaging Characteristics of Diffuse Intracranial Dolichoectasia","volume":"38","author":"W Brinjikji","year":"2017","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1212\/WNL.47.5.1125","article-title":"Arterial territories of human brain: brainstem and cerebellum","volume":"47","author":"L Tatu","year":"1996","journal-title":"Neurology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1212\/WNL.50.6.1699","article-title":"Arterial territories of the human brain: cerebral hemispheres","volume":"50","author":"L Tatu","year":"1998","journal-title":"Neurology"},{"key":"ref30","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting Linear Mixed-Effects Models Using lme4","volume":"67","author":"D Bates","year":"2015","journal-title":"J Stat Softw"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1161\/STROKEAHA.117.017406","article-title":"Dolichoectasia and Small Vessel Disease in Young Patients with Transient Ischemic Attack and Stroke","volume":"48","author":"V Thijs","year":"2017","journal-title":"Stroke"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jstrokecerebrovasdis.2010.02.015","article-title":"Cerebral microbleeds and dilative remodeling of the basilar artery: A magnetic resonance imaging study","volume":"20","author":"H Ichikawa","year":"2011","journal-title":"J Stroke Cerebrovasc Dis. Elsevier Ltd"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s00062-015-0458-z","article-title":"Imaging of Cerebral Microbleeds","volume":"25","author":"J Linn","year":"2015","journal-title":"Clin Neuroradiol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.3174\/ajnr.A4248","article-title":"SWI or T2*: Which MRI Sequence to Use in the Detection of Cerebral Microbleeds? The Karolinska Imaging Dementia Study","volume":"36","author":"S Shams","year":"2015","journal-title":"Am J Neuroradiol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1212\/01.wnl.0000307750.41970.d9","article-title":"Prevalence and risk factors of cerebral microbleeds: The Rotterdam Scan Study","volume":"70","author":"MW Vernooij","year":"2008","journal-title":"Neurology"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s11936-011-0119-8","article-title":"Recent advances in magnetic resonance imaging in posterior circulation stroke: implications for diagnosis and prognosis","volume":"13","author":"A F\u00f6rster","year":"2011","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1161\/STROKEAHA.112.658500","article-title":"Risk factors and stroke mechanisms in atherosclerotic stroke: intracranial compared with extracranial and anterior compared with posterior circulation disease","volume":"43","author":"JS Kim","year":"2012","journal-title":"Stroke"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1161\/STROKEAHA.116.015630","article-title":"Histopathological Differences Between the Anterior and Posterior Brain Arteries as a Function of Aging","volume":"48","author":"W Roth","year":"2017","journal-title":"Stroke"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1159\/000330346","article-title":"Thrombolysis in posterior circulation stroke: stroke subtypes and patterns, complications and outcome","volume":"32","author":"A F\u00f6rster","year":"2011","journal-title":"Cerebrovasc Dis"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1111\/ijs.12626","article-title":"Posterior vs. anterior circulation infarction: demography, outcomes, and frequency of hemorrhage after thrombolysis","volume":"10","author":"T Dor\u0148\u00e1k","year":"2015","journal-title":"Int J Stroke"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1212\/WNL.0000000000004259","article-title":"Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds","volume":"89","author":"A Charidimou","year":"2017","journal-title":"Neurology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0196149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T09:43:57Z","timestamp":1660988637000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0196149"}},"subtitle":[],"editor":[{"given":"Stephan","family":"Meckel","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,4,19]]},"references-count":41,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,4,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0196149","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,19]]}}}