{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:47:38Z","timestamp":1790808458571,"version":"4.1.0"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["DRO, Nemocnice Na Homolce - NNH, 00023884, IG150501"],"award-info":[{"award-number":["DRO, Nemocnice Na Homolce - NNH, 00023884, IG150501"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["SVV260147\/2015"],"award-info":[{"award-number":["SVV260147\/2015"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0196321","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T17:28:37Z","timestamp":1524590917000},"page":"e0196321","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":40,"title":["Electrocardiogram-synchronized pulsatile extracorporeal life support preserves left ventricular function and coronary flow in a porcine model of cardiogenic shock"],"prefix":"10.1371","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9550-222X","authenticated-orcid":true,"given":"Petr","family":"Ostadal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikulas","family":"Mlcek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Gorhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Simundic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svitlana","family":"Strunina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matej","family":"Hrachovina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kr\u00fcger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Vondrakova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Janotka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Hala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Mates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Ostadal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C.","family":"Leiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otomar","family":"Kittnar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Neuzil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2018,4,24]]},"reference":[{"issue":"25 Pt A","key":"ref1","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/j.jacc.2014.03.046","article-title":"Extracorporeal membrane oxygenation in cardiopulmonary disease in adults","volume":"63","author":"D Abrams","year":"2014","journal-title":"Journal of the American College of Cardiology"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1093\/eurheartj\/eht248","article-title":"Mechanical circulatory support in cardiogenic shock","volume":"35","author":"K Werdan","year":"2014","journal-title":"Eur Heart J"},{"key":"ref3","article-title":"ECMO: Extracorporeal Cardiopulmonary Support in Critical Care","year":"2012"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/1479-5876-10-163","article-title":"Hyperinvasive approach to out-of hospital cardiac arrest using mechanical chest compression device, prehospital intraarrest cooling, extracorporeal life support and early invasive assessment compared to standard of care. A randomized parallel groups comparative study proposal. "Prague OHCA study"","volume":"10","author":"J Belohlavek","year":"2012","journal-title":"J Transl Med"},{"issue":"Suppl 2","key":"ref5","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/ejhf.857","article-title":"Extra corporeal membrane oxygenation in the therapy of cardiogenic shock (ECMO-CS): rationale and design of the multicenter randomized trial","volume":"19","author":"P Ostadal","year":"2017","journal-title":"European journal of heart failure"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/eurheartj\/ehs081","article-title":"Emergency circulatory support in refractory cardiogenic shock patients in remote institutions: a pilot study (the cardiac-RESCUE program)","volume":"34","author":"S Beurtheret","year":"2013","journal-title":"Eur Heart J"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"M339","DOI":"10.1097\/00002480-199407000-00020","article-title":"Efficacy of extracorporeal life support in the setting of adult cardiorespiratory failure","volume":"40","author":"T Pranikoff","year":"1994","journal-title":"ASAIO J"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1097\/CCM.0b013e31816f7cf7","article-title":"Outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation for refractory cardiogenic shock","volume":"36","author":"A Combes","year":"2008","journal-title":"Crit Care Med"},{"issue":"11","key":"ref9","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1046\/j.1525-1594.1999.06484.x","article-title":"Pathophysiology of cardiac extracorporeal membrane oxygenation","volume":"23","author":"BP Fuhrman","year":"1999","journal-title":"Artificial organs"},{"issue":"3","key":"ref10","first-page":"568","article-title":"Catastrophic left heart distension following initiation of venoarterial extracorporeal membrane oxygenation in a patient with mild aortic regurgitation","volume":"40","author":"D Sidebotham","year":"2012","journal-title":"Anaesthesia and intensive care"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1177\/0267659112443722","article-title":"Management of left ventricular distension during peripheral extracorporeal membrane oxygenation for cardiogenic shock","volume":"27","author":"B Soleimani","year":"2012","journal-title":"Perfusion"},{"issue":"3","key":"ref12","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1510\/icvts.2011.269795","article-title":"Left ventricle unloading by percutaneous pigtail during extracorporeal membrane oxygenation","volume":"13","author":"A Barbone","year":"2011","journal-title":"Interactive cardiovascular and thoracic surgery"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1186\/s12967-015-0634-6","article-title":"Increasing venoarterial extracorporeal membrane oxygenation flow negatively affects left ventricular performance in a porcine model of cardiogenic shock","volume":"13","author":"P Ostadal","year":"2015","journal-title":"J Transl Med"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/0022-3468(92)90103-E","article-title":"Severe myocardial dysfunction during extracorporeal membrane oxygenation","volume":"27","author":"RB Hirschl","year":"1992","journal-title":"Journal of pediatric surgery"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0022-3476(05)82163-8","article-title":"Changes in cardiac function during extracorporeal membrane oxygenation for persistent pulmonary hypertension in the newborn infant","volume":"118","author":"TR Kimball","year":"1991","journal-title":"The Journal of pediatrics"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/BF00793945","article-title":"Left ventricular performance in neonates on extracorporeal membrane oxygenation","volume":"13","author":"F Berdjis","year":"1992","journal-title":"Pediatric cardiology"},{"issue":"6","key":"ref17","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s12265-010-9215-5","article-title":"Extracorporeal membrane oxygenation induced cardiac dysfunction in newborn lambs","volume":"3","author":"LA Pyles","year":"2010","journal-title":"Journal of cardiovascular translational research"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/S0003-4975(00)02280-3","article-title":"Effect of extracorporeal membrane oxygenation on left ventricular function of swine","volume":"71","author":"I Shen","year":"2001","journal-title":"The Annals of thoracic surgery"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/S0003-4975(00)02281-5","article-title":"Left ventricular dysfunction during extracorporeal membrane oxygenation in a hypoxemic swine model","volume":"71","author":"I Shen","year":"2001","journal-title":"The Annals of thoracic surgery"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.echo.2012.02.009","article-title":"Two-dimensional strain rate and Doppler tissue myocardial velocities: analysis by echocardiography of hemodynamic and functional changes of the failed left ventricle during different degrees of extracorporeal life support","volume":"25","author":"N Aissaoui","year":"2012","journal-title":"Journal of the American Society of Echocardiography: official publication of the American Society of Echocardiography"},{"issue":"7","key":"ref21","doi-asserted-by":"crossref","first-page":"E90","DOI":"10.1111\/aor.12482","article-title":"In Vivo Hemodynamic Performance Evaluation of Novel Electrocardiogram-Synchronized Pulsatile and Nonpulsatile Extracorporeal Life Support Systems in an Adult Swine Model","volume":"39","author":"S Wang","year":"2015","journal-title":"Artificial organs"},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","first-page":"E127","DOI":"10.1111\/aor.12484","article-title":"Impact of Pulsatility and Flow Rates on Hemodynamic Energy Transmission in an Adult Extracorporeal Life Support System","volume":"39","author":"R Wolfe","year":"2015","journal-title":"Artificial organs"},{"issue":"4","key":"ref23","doi-asserted-by":"crossref","first-page":"711","DOI":"10.33549\/physiolres.933294","article-title":"Novel porcine model of acute severe cardiogenic shock developed by upper-body hypoxia","volume":"65","author":"P Ostadal","year":"2016","journal-title":"Physiol Res"},{"issue":"6","key":"ref24","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1161\/CIRCEP.112.973123","article-title":"Direct comparison of percutaneous circulatory support systems in specific hemodynamic conditions in a porcine model","volume":"5","author":"P Ostadal","year":"2012","journal-title":"Circ Arrhythm Electrophysiol"},{"issue":"1","key":"ref25","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12967-015-0760-1","article-title":"Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO","volume":"14","author":"M Broome","year":"2016","journal-title":"J Transl Med"},{"issue":"1","key":"ref26","first-page":"5","article-title":"Left ventricle unloading during veno-arterial extracorporeal membrane oxygenation","volume":"3","author":"S Strunina","year":"2016","journal-title":"Current Research: Cardiology"},{"issue":"5","key":"ref27","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1177\/2048872614561481","article-title":"First-in-man analysis of the i-cor assist device in patients with cardiogenic shock","volume":"4","author":"J Poss","year":"2015","journal-title":"European heart journal Acute cardiovascular care"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/aor.12413","article-title":"Pulsatile venoarterial perfusion using a novel synchronized cardiac assist device augments coronary artery blood flow during ventricular fibrillation","volume":"39","author":"B Cremers","year":"2015","journal-title":"Artificial organs"},{"issue":"11","key":"ref29","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1111\/j.1525-1594.2011.01378.x","article-title":"Comparison of parameters for detection of splanchnic hypoxia in children undergoing cardiopulmonary bypass with pulsatile versus nonpulsatile normothermia or hypothermia during congenital heart surgeries","volume":"35","author":"AR Karaci","year":"2011","journal-title":"Artificial organs"},{"issue":"1","key":"ref30","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/aor.12588","article-title":"Effect of the Pulsatile Extracorporeal Membrane Oxygenation on Hemodynamic Energy and Systemic Microcirculation in a Piglet Model of Acute Cardiac Failure","volume":"40","author":"H Itoh","year":"2016","journal-title":"Artificial organs"},{"issue":"9","key":"ref31","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/aor.12466","article-title":"Laboratory Evaluation of Hemolysis and Systemic Inflammatory Response in Neonatal Nonpulsatile and Pulsatile Extracorporeal Life Support Systems","volume":"39","author":"S Wang","year":"2015","journal-title":"Artificial organs"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0196321","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,20]],"date-time":"2022-08-20T21:55:57Z","timestamp":1661032557000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0196321"}},"subtitle":[],"editor":[{"given":"Vincenzo","family":"Lionetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,4,24]]},"references-count":31,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,4,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0196321","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,24]]}}}