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Hydatidosis in Nekemet: prevalence in slaughtered cattle and sheep estimated economic loss and incidence in stray dog. DVM Thesis Addis Ababa University, Faculty of Veterinary Medicine, Debre Zeit, Ethiopia. 1994."},{"issue":"7","key":"ref47","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1007\/s11250-009-9338-3","article-title":"Major metacestodes in cattle slaughtered at Wolaita Soddo Municipal abattoir, Southern Ethiopia: Prevalence, cyst viability, organ distribution and socioeconomic implications","volume":"41","author":"A Regassa","year":"2009","journal-title":"Tropical animal health and production"},{"issue":"3","key":"ref48","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.actatropica.2009.10.019","article-title":"Hydatidosis: prevalence and its economic importance in ruminants slaughtered at Adama municipal abattoir, Central Oromia, Ethiopia","volume":"113","author":"A Getaw","year":"2010","journal-title":"Acta Tropica"},{"key":"ref49","article-title":"Cystic echinococcosis in cattle slaughtered at Shashemanne Municipal Abattoir, south central Oromia, Ethiopia: 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