{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:39:11Z","timestamp":1782837551325,"version":"3.54.5"},"reference-count":21,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T00:00:00Z","timestamp":1531353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008089","name":"Fondazione Internazionale Menarini","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0199770","type":"journal-article","created":{"date-parts":[[2018,7,12]],"date-time":"2018-07-12T13:45:40Z","timestamp":1531403140000},"page":"e0199770","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Characteristics, treatment and quality of life of stable coronary artery disease patients with or without angina: Insights from the START study"],"prefix":"10.1371","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8552-1272","authenticated-orcid":true,"given":"Leonardo","family":"De Luca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pier Luigi","family":"Temporelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8614-785X","authenticated-orcid":true,"given":"Donata","family":"Lucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Furio","family":"Colivicchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Calabr\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmine","family":"Riccio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Amico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Mascia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Proia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Di Lenarda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele Massimo","family":"Gulizia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the START Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2018,7,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1161\/CIR.0000000000000095","article-title":"2014 ACC\/AHA\/AATS\/PCNA\/SCAI\/STS focused update of the guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines, and the American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons","volume":"130","author":"SD Fihn","year":"2014","journal-title":"Circulation"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"G Montalescot","year":"2013","journal-title":"Eur Heart J"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1093\/eurheartj\/ehi171","article-title":"Euro Heart Survey Investigators. The clinical characteristics and investigations planned in patients with stable angina presenting to cardiologists in Europe: from the Euro Heart Survey of Stable Angina","volume":"26","author":"CA Daly","year":"2005","journal-title":"Eur Heart J"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1093\/eurheartj\/ehv437","article-title":"EURObservational Research Programme: the Chronic Ischaemic Cardiovascular Disease Registry: Pilot phase (CICD-PILOT)","volume":"37","author":"M Komajda","year":"2016","journal-title":"Eur Heart J"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1001\/jamainternmed.2014.3773","article-title":"Prospective Observational Longitudinal Registry of Patients with Stable Coronary Artery Disease (CLARIFY) Investigators. Prevalence of anginal symptoms and myocardial ischemia and their effect on clinical outcomes in outpatients with stable coronary artery disease: data from the International Observational CLARIFY Registry","volume":"174","author":"PG Steg","year":"2014","journal-title":"JAMA Intern Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/2047487317740663","article-title":"START Investigators. Current management and treatment of patients with stable coronary artery diseases presenting to cardiologists in different clinical contexts: A prospective, observational, nationwide study","volume":"25","author":"L De Luca","year":"2018","journal-title":"Eur J Prev Cardiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1007\/s11136-011-9903-x","article-title":"Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L)","volume":"20","author":"M Herdman","year":"2011","journal-title":"Quality of Life Research"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1001\/archinternmed.2009.295","article-title":"The prevalence of weekly angina among patients with chronic stable angina in primary care practices: The Coronary Artery Disease in General Practice (CADENCE) Study","volume":"169","author":"JF Beltrame","year":"2009","journal-title":"Arch Intern Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/clc.22488","article-title":"Angina in coronary artery disease patients with and without diabetes: US National Health and Nutrition Examination Survey 2001\u20132010","volume":"39","author":"G Hui","year":"2016","journal-title":"Clin Cardiol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/clc.22628","article-title":"The prevalence and management of angina among patients with chronic coronary artery disease across US outpatient cardiology practices: insights from the Angina Prevalence and Provider Evaluation of Angina Relief (APPEAR) study","volume":"40","author":"F Kureshi","year":"2017","journal-title":"Clin Cardiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.amjcard.2016.07.040","article-title":"Relation of angina pectoris to outcomes, quality of life, and response to exercise training in patients with chronic heart failure (from HF-ACTION)","volume":"118","author":"KS Parikh","year":"2016","journal-title":"Am J Cardiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1056\/NEJMcp1502240","article-title":"Chronic Stable Angina","volume":"374","author":"EM Ohman","year":"2016","journal-title":"N Engl J Med"},{"issue":"10","key":"ref13","doi-asserted-by":"crossref","first-page":"e004080","DOI":"10.1161\/JAHA.116.004080","article-title":"Angina and Future Cardiovascular Events in Stable Patients With Coronary Artery Disease: Insights From the Reduction of Atherothrombosis for Continued Health (REACH) Registry","volume":"5","author":"A Eisen","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"f4726","DOI":"10.1136\/bmj.f4726","article-title":"Novel drugs for treating angina","volume":"347","author":"DA Jones","year":"2013","journal-title":"BMJ"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/clc.22479","article-title":"Investigators of the Prospective, Noninterventional, Observational Study of the Antianginal Efficacy of Ivabradine During a 4-Month Treatment of a Greek Population With Coronary Artery Disease. Treatment of Stable Angina Pectoris With Ivabradine in Everyday Practice: A Pan\u2010Hellenic, Prospective, Noninterventional Study","volume":"38","author":"J Zarifis","year":"2015","journal-title":"Clin Cardiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1056\/NEJMoa070829","article-title":"COURAGE Trial Research Group. Optimal medical therapy with or without PCI for stable coronary disease","volume":"356","author":"WE Boden","year":"2007","journal-title":"N Engl J Med"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1056\/NEJMoa1505532","article-title":"COURAGE Trial Investigators. Effect of PCI on long-term survival in patients with stable ischemic heart disease","volume":"373","author":"SP Sedlis","year":"2015","journal-title":"N Engl J Med"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1001\/jamainternmed.2013.12855","article-title":"Percutaneous coronary intervention outcomes in patients with stable obstructive coronary artery disease and myocardial ischemia: a collaborative meta-analysis of contemporary randomized clinical trials","volume":"174","author":"K Stergiopoulos","year":"2014","journal-title":"JAMA Intern Med"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.jacc.2008.06.015","article-title":"Optimal medical therapy is a proven option for chronic stable angina","volume":"52","author":"RA O'Rourke","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1161\/CIRCULATIONAHA.104.521864","article-title":"Percutaneous coronary intervention versus conservative therapy in nonacute coronary artery disease: a meta-analysis","volume":"111","author":"DG Katritsis","year":"2005","journal-title":"Circulation"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(17)32714-9","article-title":"ORBITA Investigators. Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial","volume":"391","author":"R Al-Lamee","year":"2018","journal-title":"Lancet"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0199770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T11:00:57Z","timestamp":1540033257000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0199770"}},"subtitle":[],"editor":[{"given":"Giuseppe","family":"And\u00f2","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,7,12]]},"references-count":21,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,7,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0199770","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,12]]}}}