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non-serotonergic projections from the raphe nuclei to the piriform cortex in the rat: a cholera toxin B subunit (CTb) and 5-HT immunohistochemical study","volume":"671","author":"F Datiche","year":"1999","journal-title":"Brain Res"},{"issue":"5","key":"ref74","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0361-9230(91)90044-K","article-title":"Investigations of origins of serotonergic projection to developing rat visual cortex: a combined retrograde tracing and immunohistochemical study","volume":"27","author":"T Koh","year":"1991","journal-title":"Brain Res Bull"},{"issue":"4","key":"ref75","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/0306-4522(82)90054-9","article-title":"Identification of serotonin and non-serotonin-containing neurons of the mid-brain raphe projecting to the entorhinal area and the hippocampal formation. A combined immunohistochemical and fluorescent retrograde tracing study in the rat brain","volume":"7","author":"C K\u00f6hler","year":"1982","journal-title":"Neuroscience"},{"issue":"6","key":"ref76","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/0361-9230(84)90232-6","article-title":"Organization of raphe-cortical projections in rat: a quantitative retrograde study","volume":"13","author":"E O'Hearn","year":"1984","journal-title":"Brain Res Bull"},{"issue":"3","key":"ref77","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/cne.903210314","article-title":"Retrograde tracing of projections between the nucleus submedius, the ventrolateral orbital cortex, and the midbrain in the rat","volume":"321","author":"JA Coffield","year":"1992","journal-title":"J Comp Neurol"},{"issue":"1","key":"ref78","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0306-4522(93)90570-6","article-title":"Sources of cortical, hypothalamic and spinal serotonergic projections: topical organization within the nucleus raphe dorsalis","volume":"56","author":"VN Kazakov","year":"1993","journal-title":"Neuroscience"},{"issue":"1","key":"ref79","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/cne.902050107","article-title":"Brainstem innervation of prefrontal and anterior cingulate cortex in the rhesus monkey revealed by retrograde transport of HRP","volume":"205","author":"LJ Porrino","year":"1982","journal-title":"J Comp Neurol"},{"issue":"4","key":"ref80","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1002\/cne.902490403","article-title":"Topographical distribution of dorsal and median raphe neurons projecting to motor, sensorimotor, and visual cortical areas in the rat","volume":"249","author":"BD Waterhouse","year":"1986","journal-title":"J Comp Neurol"},{"issue":"3","key":"ref81","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1002\/cne.1033","article-title":"Topographic organization and neurochemical identity of dorsal raphe neurons that project to the trigeminal somatosensory pathway in the rat","volume":"435","author":"ML Kirifides","year":"2001","journal-title":"Comp Neurol"},{"issue":"2","key":"ref82","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0306-4522(97)00268-6","article-title":"Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods","volume":"82","author":"C Peyron","year":"1998","journal-title":"Neuroscience"},{"issue":"2","key":"ref83","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1002\/(SICI)1096-9861(19991018)413:2<342::AID-CNE12>3.0.CO;2-#","article-title":"Topographic organization of serotonergic dorsal raphe neurons projecting to the superior colliculus in the Mongolian gerbil (Meriones unguiculatus)","volume":"413","author":"S Janusonis","year":"1999","journal-title":"J Comp Neurol"},{"issue":"2","key":"ref84","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/0306-4522(87)90364-2","article-title":"Dorsal raphe serotonergic projection to the retina. 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