{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T03:35:58Z","timestamp":1778902558053,"version":"3.51.4"},"reference-count":62,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T00:00:00Z","timestamp":1531958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001824","name":"Grantov\u00e1 Agentura \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["GA17-25455S"],"award-info":[{"award-number":["GA17-25455S"]}],"id":[{"id":"10.13039\/501100001824","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["17-31333A"],"award-info":[{"award-number":["17-31333A"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010653","name":"Masaryk University","doi-asserted-by":"crossref","award":["Junior Researcher Award"],"award-info":[{"award-number":["Junior Researcher Award"]}],"id":[{"id":"10.13039\/501100010653","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0201068","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T18:40:05Z","timestamp":1532025605000},"page":"e0201068","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":36,"title":["Multi-locus sequence typing of Treponema pallidum subsp. pallidum present in clinical samples from France: Infecting treponemes are genetically diverse and belong to 18 allelic profiles"],"prefix":"10.1371","volume":"13","author":[{"given":"Petra","family":"Posp\u00ed\u0161ilov\u00e1","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe Alain","family":"Grange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Grillov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lenka","family":"Mikalov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pervenche","family":"Martinet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Janier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annie","family":"Vermersch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadjet","family":"Benhaddou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Del Giudice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Alcaraz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Truchetet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6237-4951","authenticated-orcid":true,"given":"Nicolas","family":"Dupin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4176-3464","authenticated-orcid":true,"given":"David","family":"\u0160majs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,7,19]]},"reference":[{"issue":"12","key":"ref1","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/nrmicro.2016.141","article-title":"Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen","volume":"14","author":"JD Radolf","year":"2016","journal-title":"Nat Rev Microbiol"},{"issue":"12","key":"ref2","doi-asserted-by":"crossref","first-page":"e0143304","DOI":"10.1371\/journal.pone.0143304","article-title":"Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting","volume":"10","author":"L Newman","year":"2015","journal-title":"PLoS One"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"17073","DOI":"10.1038\/nrdp.2017.73","article-title":"Syphilis","volume":"3","author":"RW Peeling","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.meegid.2018.03.015","article-title":"Genetics of human and animal uncultivable treponemal pathogens","volume":"61","author":"D \u0160majs","year":"2018","journal-title":"Infect Genet Evol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"16245","DOI":"10.1038\/nmicrobiol.2016.245","article-title":"Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster","volume":"2","author":"N Arora","year":"2016","journal-title":"Nat Microbiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"16190","DOI":"10.1038\/nmicrobiol.2016.190","article-title":"Genome-scale analysis of the non-cultivable Treponema pallidum reveals extensive within-patient genetic variation","volume":"2","author":"M Pinto","year":"2016","journal-title":"Nat Microbiol"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/00007435-199809000-00004","article-title":"Molecular subtyping of Treponema pallidum subspecies pallidum","volume":"25","author":"A Pillay","year":"1998","journal-title":"Sex Transm Dis"},{"issue":"10","key":"ref8","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/OLQ.0b013e3181e1a77a","article-title":"Molecular epidemiology of syphilis\u2014San Francisco, 2004\u20132007","volume":"37","author":"KA Katz","year":"2010","journal-title":"Sex Transm Dis"},{"issue":"9","key":"ref9","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1086\/656533","article-title":"Enhanced molecular typing of treponema pallidum: geographical distribution of strain types and association with neurosyphilis","volume":"202","author":"C Marra","year":"2010","journal-title":"J Infect Dis"},{"issue":"3","key":"ref10","first-page":"105","article-title":"[Molecular detection and subtyping of Treponema pallidum subsp. pallidum in clinical specimens]","volume":"55","author":"M Flasarov\u00e1","year":"2006","journal-title":"Epidemiol Mikrobiol Imunol"},{"issue":"6","key":"ref11","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2340\/00015555-1335","article-title":"Sequencing-based molecular typing of treponema pallidum strains in the Czech Republic: all identified genotypes are related to the sequence of the SS14 strain","volume":"92","author":"M Flasarov\u00e1","year":"2012","journal-title":"Acta Derm Venereol"},{"issue":"Pt 6","key":"ref12","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1099\/jmm.0.007542-0","article-title":"Macrolide treatment failure in a case of secondary syphilis: a novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp. pallidum","volume":"58","author":"P Matejkov\u00e1","year":"2009","journal-title":"J Med Microbiol"},{"issue":"2","key":"ref13","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1128\/JCM.02209-06","article-title":"Detection of Treponema pallidum subsp. pallidum from skin lesions, serum, and cerebrospinal fluid in an infant with congenital syphilis after clindamycin treatment of the mother during pregnancy","volume":"45","author":"V Woznicov\u00e1","year":"2007","journal-title":"J Clin Microbiol"},{"issue":"11","key":"ref14","doi-asserted-by":"crossref","first-page":"e1273","DOI":"10.1371\/journal.pntd.0001273","article-title":"Molecular typing of Treponema pallidum: a systematic review and meta-analysis","volume":"5","author":"RR Peng","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"issue":"12","key":"ref15","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.1172\/JCI57173","article-title":"Syphilis: using modern approaches to understand an old disease","volume":"121","author":"EL Ho","year":"2011","journal-title":"J Clin Invest"},{"issue":"1","key":"ref16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/QCO.0000000000000124","article-title":"Syphilis testing, typing, and treatment follow-up: a new era for an old disease","volume":"28","author":"C Tipple","year":"2015","journal-title":"Curr Opin Infect Dis"},{"issue":"8","key":"ref17","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1128\/JCM.00959-16","article-title":"Treponema pallidum Strain Types and Association with Macrolide Resistance in Sydney, Australia: New TP0548 Gene Types Identified","volume":"54","author":"P Read","year":"2016","journal-title":"J Clin Microbiol"},{"issue":"4","key":"ref18","doi-asserted-by":"crossref","first-page":"e0175477","DOI":"10.1371\/journal.pone.0175477","article-title":"Molecular subtyping of Treponema pallidum and associated factors of serofast status in early syphilis patients: Identified novel genotype and cytokine marker","volume":"12","author":"RL Zhang","year":"2017","journal-title":"PLoS One"},{"issue":"2","key":"ref19","doi-asserted-by":"crossref","first-page":"e0172905","DOI":"10.1371\/journal.pone.0172905","article-title":"Molecular typing of Treponema pallidum isolates from Buenos Aires, Argentina: Frequent Nichols-like isolates and low levels of macrolide resistance","volume":"12","author":"L Gallo Vaulet","year":"2017","journal-title":"PLoS One"},{"issue":"10","key":"ref20","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1128\/JCM.01292-14","article-title":"Molecular typing of Treponema pallidum in the Czech Republic during 2011 to 2013: increased prevalence of identified genotypes and of isolates with macrolide resistance","volume":"52","author":"L Grillov\u00e1","year":"2014","journal-title":"J Clin Microbiol"},{"key":"ref21","article-title":"Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new Multilocus Sequence Typing scheme","author":"L Grillov\u00e1","journal-title":"Plos One"},{"issue":"6","key":"ref22","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2340\/00015555-1335","article-title":"Sequencing-based Molecular Typing of Treponema pallidum Strains in the Czech Republic: All Identified Genotypes are Related to the Sequence of the SS14 Strain","volume":"92","author":"M Flasarova","year":"2012","journal-title":"Acta Dermato-Venereologica"},{"key":"ref23","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2180-13-178","article-title":"Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient","volume":"13","author":"L Mikalova","year":"2013","journal-title":"Bmc Microbiology"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1128\/JCM.40.1.256-258.2002","article-title":"Molecular typing of Treponema pallidum in South Africa: cross-sectional studies","volume":"40","author":"A Pillay","year":"2002","journal-title":"J Clin Microbiol"},{"issue":"Pt 6","key":"ref25","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1099\/jmm.0.46943-0","article-title":"Molecular characterization and analysis of a gene encoding the acidic repeat protein (Arp) of Treponema pallidum","volume":"56","author":"H Liu","year":"2007","journal-title":"J Med Microbiol"},{"issue":"11","key":"ref26","doi-asserted-by":"crossref","first-page":"3802","DOI":"10.1128\/JCM.00128-08","article-title":"Molecular typing of treponema pallidum clinical strains from Lisbon, Portugal","volume":"46","author":"C Florindo","year":"2008","journal-title":"J Clin Microbiol"},{"issue":"3","key":"ref27","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/sextrans-2012-050622","article-title":"Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis","volume":"89","author":"A Gayet-Ageron","year":"2013","journal-title":"Sex Transm Infect"},{"issue":"8","key":"ref28","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1097\/OLQ.0000000000000006","article-title":"Molecular subtyping of Treponema pallidum in Paris, France","volume":"40","author":"PA Grange","year":"2013","journal-title":"Sex Transm Dis"},{"issue":"8","key":"ref29","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/OLQ.0000000000000474","article-title":"Treponema pallidum 11qj Subtype May Correspond to a Treponema pallidum Subsp","volume":"43","author":"PA Grange","year":"2016","journal-title":"Endemicum Strain. Sex Transm Dis"},{"issue":"9","key":"ref30","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/OLQ.0000000000000165","article-title":"The molecular typing data of recently identified subtype 11q\/j of Treponema pallidum subsp. pallidum suggest imported case of yaws","volume":"41","author":"L Mikalov\u00e1","year":"2014","journal-title":"Sex Transm Dis"},{"key":"ref31","article-title":"Bejel in Cuba: molecular identification of Treponema pallidum subsp. endemicum in patients diagnosed with venereal syphilis","author":"AA Noda","year":"2018","journal-title":"Clin Microbiol Infect"},{"issue":"12","key":"ref32","doi-asserted-by":"crossref","first-page":"e15713","DOI":"10.1371\/journal.pone.0015713","article-title":"Genome analysis of Treponema pallidum subsp. pallidum and subsp. pertenue strains: most of the genetic differences are localized in six regions","volume":"5","author":"L Mikalov\u00e1","year":"2010","journal-title":"PLoS One"},{"issue":"5\u20136","key":"ref33","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ijmm.2014.04.007","article-title":"Syphilis-causing strains belong to separate SS14-like or Nichols-like groups as defined by multilocus analysis of 19 Treponema pallidum strains","volume":"304","author":"L Nechv\u00e1tal","year":"2014","journal-title":"Int J Med Microbiol"},{"key":"ref34","first-page":"181","article-title":"there are two genetically distinct syphilis-causing strains?","volume":"7","author":"D Smajs","year":"2016"},{"issue":"4","key":"ref35","doi-asserted-by":"crossref","first-page":"678","DOI":"10.4269\/ajtmh.15-0316","article-title":"Macrolide Resistance in the Syphilis Spirochete, Treponema pallidum ssp. pallidum: Can We Also Expect Macrolide-Resistant Yaws Strains?","volume":"93","author":"D \u0160majs","year":"2015","journal-title":"Am J Trop Med Hyg"},{"issue":"5","key":"ref36","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1128\/IAI.01424-07","article-title":"A novel Treponema pallidum antigen, TP0136, is an outer membrane protein that binds human fibronectin","volume":"76","author":"MB Brinkman","year":"2008","journal-title":"Infect Immun"},{"key":"ref37","article-title":"The Treponema pallidum Outer Membrane","author":"JD Radolf","year":"2017","journal-title":"Curr Top Microbiol Immunol"},{"issue":"3","key":"ref38","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1128\/JCM.00702-11","article-title":"Evaluation of a PCR test for detection of treponema pallidum in swabs and blood","volume":"50","author":"PA Grange","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref39","first-page":"1","article-title":"Case definition of infectious conditions under public health surveillance","year":"1997","journal-title":"Morb. Mortal. Wkly. Rep."},{"issue":"3","key":"ref40","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1128\/AAC.44.3.806-807.2000","article-title":"A point mutation associated with bacterial macrolide resistance is present in both 23S rRNA genes of an erythromycin-resistant Treponema pallidum clinical isolate","volume":"44","author":"LV Stamm","year":"2000","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"ref41","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/OLQ.0000000000000486","article-title":"Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains","volume":"43","author":"BJ Molini","year":"2016","journal-title":"Sex Transm Dis"},{"issue":"12","key":"ref42","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/molbev\/mst197","article-title":"MEGA6: Molecular Evolutionary Genetics Analysis version 6.0","volume":"30","author":"K Tamura","year":"2013","journal-title":"Mol Biol Evol"},{"issue":"1","key":"ref43","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/oxfordjournals.molbev.a026036","article-title":"Median-joining networks for inferring intraspecific phylogenies","volume":"16","author":"HJ Bandelt","year":"1999","journal-title":"Mol Biol Evol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1096-0031.2010.00329.x","article-title":"SequenceMatrix: Concatenation Software for the Fast Assembly of Multi-Gene Datasets with Character Set and Codon Information","volume":"27","author":"G Vaidya","year":"2011","journal-title":"Cladistics"},{"issue":"6","key":"ref45","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1097\/OLQ.0000000000000600","article-title":"Molecular Typing of Syphilis-Causing Strains Among Human Immunodeficiency Virus-Positive Patients in Antwerp, Belgium","volume":"44","author":"L Mikalov\u00e1","year":"2017","journal-title":"Sex Transm Dis"},{"issue":"12","key":"ref46","first-page":"B5176","article-title":"Syphilis and HIV co-infection. Epidemiology, treatment and molecular typing of Treponema pallidum","volume":"62","author":"K Salado-Rasmussen","year":"2015","journal-title":"Dan Med J"},{"issue":"6","key":"ref47","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1136\/sextrans-2011-050082","article-title":"High prevalence of macrolide resistant Treponema pallidum strains in a London centre","volume":"87","author":"C Tipple","year":"2011","journal-title":"Sex Transm Infect"},{"issue":"8","key":"ref48","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1097\/OLQ.0000000000000478","article-title":"Molecular Typing of Treponema pallidum in Ocular Syphilis","volume":"43","author":"S Oliver","year":"2016","journal-title":"Sex Transm Dis"},{"issue":"12","key":"ref49","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1097\/OLQ.0b013e31826ae7a8","article-title":"Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington","volume":"39","author":"M Grimes","year":"2012","journal-title":"Sex Transm Dis"},{"issue":"4","key":"ref50","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/OLQ.0000000000000741","article-title":"Enhanced Molecular Typing of Treponema pallidum subspecies pallidum Strains From 4 Italian Hospitals Shows Geographical Differences in Strain Type Heterogeneity, Widespread Resistance to Macrolides, and Lack of Mutations Associated With Doxycycline Resistance","volume":"45","author":"L Giacani","year":"2018","journal-title":"Sex Transm Dis"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/OLQ.0b013e318232697d","article-title":"Molecular typing of Treponema pallidum causing early syphilis in China: a cross-sectional study","volume":"39","author":"RR Peng","year":"2012","journal-title":"Sex Transm Dis"},{"issue":"7","key":"ref52","doi-asserted-by":"crossref","first-page":"e0159787","DOI":"10.1371\/journal.pone.0159787","article-title":"High Resistance to Azithromycin in Clinical Samples from Patients with Sexually Transmitted Diseases in Guangxi Zhuang Autonomous Region, China","volume":"11","author":"B Zhu","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"ref53","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1111\/apm.12724","article-title":"Enhanced molecular typing of Treponema pallidum identified a new tp0548 Gene type in Shandong, China","volume":"125","author":"Z Li","year":"2017","journal-title":"APMIS"},{"issue":"5","key":"ref54","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/OLQ.0000000000000445","article-title":"Molecular Subtyping and Surveillance of Resistance Genes In Treponema pallidum DNA From Patients With Secondary and Latent Syphilis in Hunan, China","volume":"43","author":"Y Xiao","year":"2016","journal-title":"Sex Transm Dis"},{"issue":"11","key":"ref55","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1128\/JCM.01195-12","article-title":"Molecular typing of Treponema pallidum: a 5-year surveillance in Shanghai, China","volume":"50","author":"T Dai","year":"2012","journal-title":"J Clin Microbiol"},{"issue":"8","key":"ref56","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/1469-0691.12529","article-title":"Multicentre surveillance of prevalence of the 23S rRNA A2058G and A2059G point mutations and molecular subtypes of Treponema pallidum in Taiwan, 2009\u20132013","volume":"20","author":"BR Wu","year":"2014","journal-title":"Clin Microbiol Infect"},{"issue":"7","key":"ref57","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/apm.12541","article-title":"Syphilis epidemiology in 1994\u20132013, molecular epidemiological strain typing and determination of macrolide resistance in Treponema pallidum in 2013\u20132014 in Tuva Republic, Russia","volume":"124","author":"R Khairullin","year":"2016","journal-title":"APMIS"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ebiom.2016.07.033","article-title":"Isolation of Treponema DNA from Necrophagous Flies in a Natural Ecosystem","volume":"11","author":"S Knauf","year":"2016","journal-title":"EBioMedicine"},{"issue":"1","key":"ref59","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4056\/sigs.2615838","article-title":"Complete genome sequence of Treponema pallidum strain DAL-1","volume":"7","author":"M Zoban\u00edkov\u00e1","year":"2012","journal-title":"Stand Genomic Sci"},{"issue":"9","key":"ref60","doi-asserted-by":"crossref","first-page":"e0005894","DOI":"10.1371\/journal.pntd.0005894","article-title":"Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Ghana, Africa: Identical genome sequences in samples isolated more than 7 years apart","volume":"11","author":"M Strouhal","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"ref61","doi-asserted-by":"crossref","first-page":"e1471","DOI":"10.1371\/journal.pntd.0001471","article-title":"Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence","volume":"6","author":"D Cejkov\u00e1","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"ref62","article-title":"Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study","author":"O Mitj\u00e0","year":"2018","journal-title":"Lancet"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0201068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T22:29:02Z","timestamp":1661639342000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0201068"}},"subtitle":[],"editor":[{"given":"Antonella","family":"Marangoni","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,7,19]]},"references-count":62,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,7,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0201068","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,19]]}}}