{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T16:10:00Z","timestamp":1774282200231,"version":"3.50.1"},"reference-count":55,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T00:00:00Z","timestamp":1534118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0202050","type":"journal-article","created":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T17:29:54Z","timestamp":1534181394000},"page":"e0202050","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["Subtyping patients with somatic tinnitus: Modulation of tinnitus and history for somatic dysfunction help identify tinnitus patients with temporomandibular joint disorders"],"prefix":"10.1371","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8776-0421","authenticated-orcid":true,"given":"Massimo","family":"Ralli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Greco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando","family":"Boccassini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Altissimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Di Paolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Falasca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando","family":"De Virgilio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Polimeni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Cianfrone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"de Vincentiis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,8,13]]},"reference":[{"issue":"9904","key":"ref1","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1016\/S0140-6736(13)60142-7","article-title":"Tinnitus","volume":"382","author":"D Baguley","year":"2013","journal-title":"Lancet"},{"issue":"9","key":"ref2","doi-asserted-by":"crossref","first-page":"E1035","DOI":"10.3390\/ijerph14091035","article-title":"Work-Related Noise Exposure in a Cohort of Patients with Chronic Tinnitus: Analysis of Demographic and Audiological Characteristics","volume":"14","author":"M Ralli","year":"2017","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"ref3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0194-5998(99)70123-3","article-title":"Tinnitus severity, loudness, and depression","volume":"121","author":"RL Folmer","year":"1999","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0030-6665(02)00160-3","article-title":"Classification and epidemiology of tinnitus","volume":"36","author":"AJ Heller","year":"2003","journal-title":"Otolaryngol Clin North Am"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/S1474-4422(13)70160-1","article-title":"Tinnitus: causes and clinical management","volume":"12","author":"B Langguth","year":"2013","journal-title":"Lancet Neurol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-1-60761-145-5_5","article-title":"Epidemiology of Tinnitus in Adults","author":"AR Moller","year":"2011","journal-title":"Textbook of Tinnitus"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1177\/0300060516672124","article-title":"Relationship between hearing function and myasthenia gravis: A contemporary review","volume":"45","author":"M Ralli","year":"2017","journal-title":"J Int Med Res"},{"issue":"3","key":"ref8","first-page":"198","article-title":"The effect of the NMDA channel blocker memantine on salicylate-induced tinnitus in rats","volume":"34","author":"M Ralli","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"issue":"2","key":"ref9","first-page":"79","article-title":"Review of salicylate-induced hearing loss, neurotoxicity, tinnitus and neuropathophysiology","volume":"34","author":"A Sheppard","year":"2014","journal-title":"Acta Otorhinolaryngol Ital"},{"issue":"3","key":"ref10","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1177\/0300060517707673","article-title":"Somatosensory tinnitus: Current evidence and future perspectives","volume":"45","author":"M Ralli","year":"2017","journal-title":"J Int Med Res"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0079-6123(07)66010-5","article-title":"Neural mechanisms underlying somatic tinnitus","volume":"166","author":"S Shore","year":"2007","journal-title":"Prog Brain Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.heares.2015.06.005","article-title":"Tinnitus: Maladaptive auditory-somatosensory plasticity","volume":"334","author":"C Wu","year":"2016","journal-title":"Hear Res"},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1159\/000452472","article-title":"Somatosensory Tinnitus: Correlation between Cranio-Cervico-Mandibular Disorder History and Somatic Modulation","volume":"21","author":"M Ralli","year":"2016","journal-title":"Audiol Neurootol"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1055\/s-0028-1095895","article-title":"Head, Neck, and Eye Movements That Modulate Tinnitus","volume":"29","author":"R Simmons","year":"2008","journal-title":"Semin Hear"},{"issue":"4","key":"ref15","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1159\/000351685","article-title":"Prevalence and factors associated with neck and jaw muscle modulation of tinnitus","volume":"18","author":"JY Won","year":"2013","journal-title":"Audiol Neurootol"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1179\/crn.2004.024","article-title":"Muscle contractions and auditory perception in tinnitus patients and nonclinical subjects","volume":"22","author":"MD Abel","year":"2004","journal-title":"Cranio"},{"issue":"6","key":"ref17","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0196-0709(99)90074-1","article-title":"Somatic (craniocervical) tinnitus and the dorsal cochlear nucleus hypothesis","volume":"20","author":"RA Levine","year":"1999","journal-title":"Am J Otolaryngol"},{"issue":"4","key":"ref18","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00221-003-1747-3","article-title":"CNS somatosensory-auditory interactions elicit or modulate tinnitus","volume":"153","author":"RA Levine","year":"2003","journal-title":"Exp Brain Res"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0079-6123(07)66017-8","article-title":"Evidence for a tinnitus subgroup responsive to somatosensory based treatment modalities","volume":"166","author":"RA Levine","year":"2007","journal-title":"Prog Brain Res"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"e38887","DOI":"10.1371\/journal.pone.0038887","article-title":"Temporomandibular joint disorder complaints in tinnitus: further hints for a putative tinnitus subtype","volume":"7","author":"V Vielsmeier","year":"2012","journal-title":"PLoS One"},{"issue":"5","key":"ref21","doi-asserted-by":"crossref","first-page":"e0126254","DOI":"10.1371\/journal.pone.0126254","article-title":"Subtyping Somatic Tinnitus: A Cross-Sectional UK Cohort Study of Demographic, Clinical and Audiological Characteristics","volume":"10","author":"J Ward","year":"2015","journal-title":"PLoS One"},{"issue":"8","key":"ref22","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1097\/MAO.0000000000000827","article-title":"Cervical Spine Dysfunctions in Patients with Chronic Subjective Tinnitus","volume":"36","author":"J Bhatt","year":"2015","journal-title":"Otol Neurotol"},{"issue":"6","key":"ref23","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1590\/S1807-59322011000600028","article-title":"Diagnosis and management of somatosensory tinnitus: review article","volume":"66","author":"TG Sanchez","year":"2011","journal-title":"Clinics (Sao Paulo)"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/000348940711600106","article-title":"Somatic modulation of tinnitus: test reliability and results after repetitive muscle contraction training","volume":"116","author":"TG Sanchez","year":"2007","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.prosdent.2013.10.001","article-title":"Is there a link between tinnitus and temporomandibular disorders?","volume":"111","author":"R Buergers","year":"2014","journal-title":"J Prosthet Dent"},{"issue":"5","key":"ref26","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1177\/0194599811413376","article-title":"Tinnitus with temporomandibular joint disorders: a specific entity of tinnitus patients?","volume":"145","author":"V Vielsmeier","year":"2011","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"1","key":"ref27","first-page":"55","article-title":"Therapy. Int Tinnitus J","volume":"3","author":"EF Wright","year":"1997","journal-title":"Therapy. Int Tinnitus J"},{"issue":"3","key":"ref28","first-page":"186","article-title":"J Craniomandib Disord","volume":"4","author":"B Rubinstein","year":"1990","journal-title":"J Craniomandib Disord"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1179\/crn.2008.016","article-title":"Otologic symptoms of temporomandibular disorder and effect of orofacial myofunctional therapy","volume":"26","author":"CM de Felicio","year":"2008","journal-title":"Cranio"},{"issue":"2","key":"ref30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/00016350500377842","article-title":"Long-term effect on tinnitus by treatment of temporomandibular disorders: a two-year follow-up by questionnaire","volume":"64","author":"M Tullberg","year":"2006","journal-title":"Acta Odontol Scand"},{"issue":"4","key":"ref31","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/0022-3913(87)90282-4","article-title":"Tinnitus and otalgia in temporomandibular disorders","volume":"58","author":"FM Bush","year":"1987","journal-title":"J Prosthet Dent"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1080\/08869634.1987.11678198","article-title":"Effects of stomatognathic treatment on tinnitus: a retrospective study","volume":"5","author":"B Rubinstein","year":"1987","journal-title":"Cranio"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3389\/fnins.2017.00207","article-title":"Pathophysiology, Diagnosis and Treatment of Somatosensory Tinnitus: A Scoping Review","volume":"11","author":"HF Haider","year":"2017","journal-title":"Front Neurosci"},{"issue":"11","key":"ref34","doi-asserted-by":"crossref","first-page":"e0188255","DOI":"10.1371\/journal.pone.0188255","article-title":"Characteristics of somatic tinnitus patients with and without hyperacusis","volume":"12","author":"M Ralli","year":"2017","journal-title":"PLoS One"},{"issue":"1\u20132","key":"ref35","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.heares.2011.05.001","article-title":"Plasticity of somatosensory inputs to the cochlear nucleus\u2014implications for tinnitus","volume":"281","author":"SE Shore","year":"2011","journal-title":"Hear Res"},{"issue":"1\u20132","key":"ref36","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0378-5955(02)00717-7","article-title":"Expanding the biological basis of tinnitus: crossmodal origins and the role of neuroplasticity","volume":"175","author":"AT Cacace","year":"2003","journal-title":"Hear Res"},{"issue":"6","key":"ref37","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1159\/000066155","article-title":"The influence of voluntary muscle contractions upon the onset and modulation of tinnitus","volume":"7","author":"TG Sanchez","year":"2002","journal-title":"Audiol Neurootol"},{"issue":"3","key":"ref38","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1179\/crn.2012.026","article-title":"Are temporomandibular disorders and tinnitus associated?","volume":"30","author":"AD Saldanha","year":"2012","journal-title":"Cranio"},{"issue":"6","key":"ref39","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0889-5406(03)00153-7","article-title":"Prevalence of otologic complaints in patients with temporomandibular disorder","volume":"123","author":"HH Tuz","year":"2003","journal-title":"Am J Orthod Dentofacial Orthop"},{"issue":"19","key":"ref40","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1001\/jama.1979.03290450053025","article-title":"Guide for the evaluation of hearing handicap","volume":"241","year":"1979","journal-title":"JAMA"},{"issue":"1","key":"ref41","first-page":"26","article-title":"The THI questionnaire: psychometric data for reliability and validity of the Italian version","volume":"14","author":"S Passi","year":"2008","journal-title":"Int Tinnitus J"},{"issue":"3","key":"ref42","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/00003446-198205000-00006","article-title":"The hearing handicap inventory for the elderly: a new tool","volume":"3","author":"IM Ventry","year":"1982","journal-title":"Ear Hear"},{"issue":"6","key":"ref43","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1159\/000067570","article-title":"Psychometric normalization of a hyperacusis questionnaire","volume":"64","author":"S Khalfa","year":"2002","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"issue":"5","key":"ref44","first-page":"327","article-title":"[The assessment of subjective distress related to hyperacusis with a self-rating questionnaire on hypersensitivity to sound]","volume":"81","author":"M Nelting","year":"2002","journal-title":"Laryngorhinootologie"},{"issue":"1","key":"ref45","doi-asserted-by":"crossref","first-page":"6","DOI":"10.11607\/jop.1151","article-title":"Diagnostic Criteria for Temporomandibular Disorders (DC\/TMD) for Clinical and Research Applications: recommendations of the International RDC\/TMD Consortium Network* and Orofacial Pain Special Interest Groupdagger","volume":"28","author":"E Schiffman","year":"2014","journal-title":"J Oral Facial Pain Headache"},{"issue":"1","key":"ref46","first-page":"14","article-title":"Temporomandibular disorders, sleep bruxism, and primary headaches are mutually associated","volume":"27","author":"G Fernandes","year":"2013","journal-title":"J Orofac Pain"},{"issue":"12","key":"ref47","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1590\/0004-282X20130191","article-title":"Painful temporomandibular disorders, self reported tinnitus, and depression are highly associated","volume":"71","author":"G Fernandes","year":"2013","journal-title":"Arq Neuropsiquiatr"},{"issue":"3","key":"ref48","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1044\/jshd.5503.439","article-title":"Characterization of tinnitus by tinnitus patients","volume":"55","author":"JL Stouffer","year":"1990","journal-title":"J Speech Hear Disord"},{"issue":"2","key":"ref49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF00186455","article-title":"Attributes of tinnitus associated with the temporomandibular joint syndrome","volume":"249","author":"J Vernon","year":"1992","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"4","key":"ref50","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1046\/j.1365-2842.2003.01249.x","article-title":"Signs of temporomandibular disorders in tinnitus patients and in a population-based group of volunteers: results of the Study of Health in Pomerania","volume":"31","author":"O Bernhardt","year":"2004","journal-title":"J Oral Rehabil"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"824684","DOI":"10.1155\/2014\/824684","article-title":"Incidence of otolaryngological symptoms in patients with temporomandibular joint dysfunctions","volume":"2014","author":"E Ferendiuk","year":"2014","journal-title":"Biomed Res Int"},{"issue":"1","key":"ref52","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00405-015-3491-2","article-title":"Increased risk of tinnitus in patients with temporomandibular disorder: a retrospective population-based cohort study","volume":"273","author":"CF Lee","year":"2016","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"2","key":"ref53","doi-asserted-by":"crossref","first-page":"112","DOI":"10.5935\/0946-5448.20170022","article-title":"Somatic Tinnitus","volume":"21","author":"M Ralli","year":"2017","journal-title":"Int Tinnitus J"},{"issue":"1\u20132","key":"ref54","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.heares.2006.09.003","article-title":"High-frequency tinnitus without hearing loss does not mean absence of deafferentation","volume":"222","author":"N Weisz","year":"2006","journal-title":"Hear Res"},{"issue":"38","key":"ref55","doi-asserted-by":"crossref","first-page":"13452","DOI":"10.1523\/JNEUROSCI.2156-11.2011","article-title":"Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model","volume":"31","author":"R Schaette","year":"2011","journal-title":"J Neurosci"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0202050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T21:25:45Z","timestamp":1588973145000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0202050"}},"subtitle":[],"editor":[{"given":"Berthold","family":"Langguth","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,8,13]]},"references-count":55,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2018,8,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0202050","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,13]]}}}