{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T16:26:34Z","timestamp":1761927994777,"version":"3.37.3"},"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T00:00:00Z","timestamp":1535414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"An-Nan Hospital","award":["ANHRF106-07"],"award-info":[{"award-number":["ANHRF106-07"]}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST-106-2314-B-039-049"],"award-info":[{"award-number":["MOST-106-2314-B-039-049"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0202979","type":"journal-article","created":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T23:13:44Z","timestamp":1535498024000},"page":"e0202979","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effect of proton pump inhibitors on sympathetic hyperinnervation in infarcted rats: Role of magnesium"],"prefix":"10.1371","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3487-8749","authenticated-orcid":true,"given":"Tsung-Ming","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nen-Chung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinn-Zong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,8,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e0124653","DOI":"10.1371\/journal.pone.0124653","article-title":"Proton pump inhibitor usage and the risk of myocardial infarction in the general population","volume":"10","author":"NH Shah","year":"2015","journal-title":"PLoS One"},{"key":"ref2","first-page":"154861","article-title":"No Increase in Risk of Acute Myocardial Infarction in Privately Insured Adults Prescribed Proton Pump Inhibitors vs Histamine-2 Receptor Antagonists (2002\u20132014)","author":"SN Landi","year":"2018","journal-title":"Gastroenterology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"755","DOI":"10.7326\/0003-4819-151-10-200911170-00016","article-title":"van den Wall Bake AW. Hypomagnesemia induced by several proton-pump inhibitors","volume":"151","author":"MA Broeren","year":"2009","journal-title":"Ann Intern Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/MJT.0b013e31829c4c71","article-title":"Clinical predictors associated with proton pump inhibitor-induced hypomagnesemia","volume":"22","author":"S Kim","year":"2015","journal-title":"Am J Ther"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.krcp.2015.03.001","article-title":"Changes in serum magnesium concentration after use of a proton pump inhibitor in patients undergoing percutaneous coronary intervention","volume":"34","author":"SH Park","year":"2015","journal-title":"Kidney Res Clin Pract"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1023\/A:1020632505289","article-title":"The influence of hypomagnesemia on erythrocyte antioxidant enzyme defence system in mice","volume":"16","author":"A Kuzniar","year":"2003","journal-title":"Biometals"},{"key":"ref7","first-page":"29","article-title":"Alterations in magnesium and oxidative status during chronic emotional stress","volume":"13","author":"I Cernak","year":"2000","journal-title":"Magnes Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/cvr\/cvp286","article-title":"Effect of N-acetylcysteine on sympathetic hyperinnervation in post-infarcted rat hearts","volume":"85","author":"TM Lee","year":"2010","journal-title":"Cardiovasc Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.freeradbiomed.2011.01.031","article-title":"Differential effect of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in post-infarcted rat hearts","volume":"50","author":"TM Lee","year":"2011","journal-title":"Free Radical Biol Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.freeradbiomed.2014.08.022","article-title":"Antiarrhythmic effect of lithium in rats after myocardial infarction by activation of Nrf2\/HO-1 signaling","volume":"77","author":"TM Lee","year":"2014","journal-title":"Free Radic Biol Med"},{"key":"ref11","first-page":"490","article-title":"Fate of nerve fibers in necrotic, healing, and healed rat myocardium","volume":"63","author":"R Vracko","year":"1990","journal-title":"Lab Invest"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1960","DOI":"10.1161\/01.CIR.101.16.1960","article-title":"Relationship between regional cardiac hyperinnervation and ventricular arrhythmias","volume":"101","author":"JM Cao","year":"2000","journal-title":"Circulation"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/0092-8674(94)90048-5","article-title":"Functions of the neurotrophins during nervous system development: what the knockouts are teaching us","volume":"77","author":"WD Snider","year":"1994","journal-title":"Cell"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"10920","DOI":"10.1073\/pnas.95.18.10920","article-title":"Beta-adrenergic receptor-induced activation of nerve growth factor gene transcription in rat cerebral cortex involves CCAAT\/enhancer-binding protein delta","volume":"95","author":"AM Colangelo","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1126\/science.2118682","article-title":"Redox regulation of fos and jun DNA-binding activity in vitro","volume":"249","author":"C Abate","year":"1990","journal-title":"Science"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.freeradbiomed.2006.08.010","article-title":"Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons","volume":"41","author":"M Pehar","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1007\/s00424-016-1905-7","article-title":"Omeprazole suppressed plasma magnesium level and duodenal magnesium absorption in male Sprague-Dawley rats","volume":"468","author":"N Thongon","year":"2016","journal-title":"Pflugers Arch"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1038\/s41598-017-02101-8","article-title":"Oral administration of trace element magnesium significantly improving the cognition and locomotion in hepatic encephalopathy rats","volume":"7","author":"Y Li","year":"2017","journal-title":"Sci Rep"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1023\/A:1005652815921","article-title":"Protective effect of famotidine, omeprazole, and melatonin against acetylsalicylic acid-induced gastric damage in rats","volume":"46","author":"G Sener-Murato\u011flu","year":"2001","journal-title":"Dig Dis Sci"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0008-6363(00)00227-3","article-title":"Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure","volume":"49","author":"QG Xia","year":"2001","journal-title":"Cardiovasc Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2040-7378-5-6","article-title":"Magnesium treatment for neuroprotection in ischemic diseases of the brain","volume":"5","author":"T Westermaier","year":"2013","journal-title":"Exp Transl Stroke Med"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/01.RES.85.2.147","article-title":"Inhibition of copper-zinc superoxide dismutase induces cell growth, hypertrophic phenotype, and apoptosis in neonatal rat cardiac myocytes in vitro","volume":"85","author":"DA Siwik","year":"1999","journal-title":"Circ Res"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.jacc.2007.11.067","article-title":"Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts","volume":"51","author":"TM Lee","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/0735-1097(88)90110-6","article-title":"Effect of transmural versus nontransmural myocardial infarction on inducibility of ventricular arrhythmias during sympathetic stimulation in dogs","volume":"11","author":"JM Herre","year":"1988","journal-title":"J Am Coll Cardiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"H1949","DOI":"10.1152\/ajpheart.00903.2008","article-title":"Effect of ATP-sensitive potassium channel agonists on sympathetic hyperinnervation in postinfarcted rat hearts","volume":"296","author":"CS Kang","year":"2009","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1073\/pnas.83.10.3537","article-title":"Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones","volume":"83","author":"KF Meiri","year":"1986","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref27","first-page":"677","article-title":"Observations on the accumulation of noradrenaline in the proximal and distal parts of peripheral adrenergic nerves after compression","volume":"99","author":"A Dahlstrom","year":"1965","journal-title":"J Anat"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.cardiores.2004.03.009","article-title":"Adjunctive 17beta-estradiol administration reduces infarct size by altered expression of canine myocardial connexin43 protein","volume":"63","author":"TM Lee","year":"2004","journal-title":"Cardiovasc Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/0304-4165(64)90215-6","article-title":"A rapid micro method for the extraction of Ca and Mg from tissue","volume":"90","author":"MP Sparrow","year":"1964","journal-title":"Biochim Biophys Acta"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1161\/01.RES.74.5.1009","article-title":"Blockade of cardiac inflammation in magnesium deficiency by substance P receptor inhibition","volume":"74","author":"WB Weglicki","year":"1994","journal-title":"Circ Res"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1161\/01.CIR.92.8.2190","article-title":"Noninvasive measurement of tissue magnesium and correlation with cardiac levels","volume":"92","author":"MC Haigney","year":"1995","journal-title":"Circulation"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1001\/archinte.1988.00380110065013","article-title":"Magnesium metabolism. A review with special reference to the relationship between intracellular content and serum levels","volume":"148","author":"RA Reinhart","year":"1988","journal-title":"Arch Intern Med"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S0735-1097(10)80179-2","article-title":"Myocardial magnesium: relation to laboratory and clinical variables in patients undergoing cardiac surgery","volume":"17","author":"RA Reinhart","year":"1991","journal-title":"J Am Coll Cardiol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/ki.2012.462","article-title":"Proton pump inhibitors and hypomagnesemia. A rare but serious complication","volume":"83","author":"MA Perazella","year":"2013","journal-title":"Kidney Int"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1079\/BJN19750011","article-title":"Solubility and net exchange of calcium, magnesium and phosphorus in digesta flowing along the gut of the sheep","volume":"33","author":"D Ben-Ghedalia","year":"1975","journal-title":"Br J Nutr"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1684\/mrh.2015.0380","article-title":"Magnesium protects against bile duct ligation-induced liver injury in male Wistar rats","volume":"28","author":"T Eshraghi","year":"2015","journal-title":"Magnes Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/0006-291X(92)91818-B","article-title":"Regulation of intracellular Mg<sup>2+<\/sup> by superoxide in amnion cells","volume":"182","author":"N Masumoto","year":"1992","journal-title":"Biochem Biophys Res Commun"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0005-2736(00)00358-8","article-title":"Destabilization of neutrophil DADPH oxidase by ATP and other trinucleotides and its prevention by Mg<sup>2+<\/sup>","volume":"1510","author":"M Tamura","year":"2001","journal-title":"Biochem Biophys Acta"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/00004836-200001000-00006","article-title":"Vitamin B12 levels during prolonged treatment with proton pump inhibitors","volume":"30","author":"CW Howden","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.bbrc.2005.10.053","article-title":"Reactive oxygen species mediates homocysteine-induced mitochondrial biogenesis in human endothelial cells: modulation by antioxidants","volume":"338","author":"K Perez-de-Arce","year":"2005","journal-title":"Biochem Biophys Res Commun"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"e36","DOI":"10.1161\/CIRCRESAHA.116.308807","article-title":"Proton pump inhibitors accelerate endothelial senescence","volume":"118","author":"G Yepuri","year":"2016","journal-title":"Circ Res"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/BF02773807","article-title":"Effect of omeprazole on gastric acid secretion in rat: evaluation of dose, duration of effect, and route of administration","volume":"22","author":"K Segawa","year":"1987","journal-title":"Gastroenterol Jpn"},{"year":"2011","key":"ref43","article-title":"FDA Drug Safety Communication: Low Magnesium Levels Can Be Associated with Long-Term Use of Proton Pump Inhibitor Drugs (PPIs)"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/sj.bjp.0706693","article-title":"Peroxynitrite: just an oxidative\/nitrosative stressor or a physiological regulator as well?","volume":"148","author":"P Ferdinandy","year":"2006","journal-title":"Br J Pharmacol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.freeradbiomed.2011.05.004","article-title":"Reactive oxygen species in cardiovascular disease","volume":"51","author":"K Sugamura","year":"2011","journal-title":"Free Radic Biol Med"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0202979","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T11:19:57Z","timestamp":1604834397000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0202979"}},"subtitle":[],"editor":[{"given":"Vincenzo","family":"Lionetti","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,8,28]]},"references-count":45,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2018,8,28]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0202979","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2018,8,28]]}}}