{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T04:28:10Z","timestamp":1790483290535,"version":"4.1.0"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The work has been partially funded by the Fundaci\u00f3n para la Investigaci\u00f3n Biom\u00e9dica de Atenci\u00f3n Primaria (FIBAP) of the Community of Madrid","award":["Grants for Translation\/Publications 2017. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."],"award-info":[{"award-number":["Grants for Translation\/Publications 2017. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0204795","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T14:02:26Z","timestamp":1538575346000},"page":"e0204795","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["HCV seroconversion in a cohort of people who use drugs followed in a mobile harm reduction unit in Madrid: Breaking barriers for HCV elimination"],"prefix":"10.1371","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0148-2422","authenticated-orcid":true,"given":"Jorge","family":"Valencia La Rosa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Alvaro-Meca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Troya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Cuevas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2018,10,3]]},"reference":[{"key":"ref1","article-title":"Global hepatitis report 2017: World Health Organization","author":"WH Organization","year":"2017","journal-title":"Global hepatitis report 2017: World Health Organization"},{"issue":"12","key":"ref2","doi-asserted-by":"crossref","first-page":"e1208","DOI":"10.1016\/S2214-109X(17)30373-X","article-title":"Global, regional, and country-level coverage of interventions to prevent and manage HIV and hepatitis C among people who inject drugs: a systematic review","volume":"5","author":"S Larney","year":"2017","journal-title":"The Lancet Global Health"},{"issue":"12","key":"ref3","doi-asserted-by":"crossref","first-page":"e1192","DOI":"10.1016\/S2214-109X(17)30375-3","article-title":"Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review","volume":"5","author":"L Degenhardt","year":"2017","journal-title":"The Lancet Global Health"},{"issue":"9791","key":"ref4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/S0140-6736(11)61097-0","article-title":"Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews","volume":"378","author":"PK Nelson","year":"2011","journal-title":"The Lancet"},{"issue":"10","key":"ref5","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1111\/j.1360-0443.2006.01543.x","article-title":"Incidence and risk factors for hepatitis C seroconversion in injecting drug users in Australia","volume":"101","author":"L Maher","year":"2006","journal-title":"Addiction"},{"key":"ref6","article-title":"High hepatitis C virus prevalence and incidence in a community cohort of young heroin injectors in a context of extensive harm reduction programmes","author":"F Vallejo","year":"2014","journal-title":"J Epidemiol Community Health"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/01.ede.0000135170.54913.9d","article-title":"Hepatitis C virus infection among injection drug users: survival analysis of time to seroconversion","volume":"15","author":"H Hagan","year":"2004","journal-title":"Epidemiology"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1086\/605947","article-title":"Acute hepatitis C virus infection in young adult injection drug users: a prospective study of incident infection, resolution, and reinfection","volume":"200","author":"K Page","year":"2009","journal-title":"The Journal of infectious diseases"},{"issue":"1","key":"ref9","first-page":"23","article-title":"High hepatitis C virus prevalence and incidence among Canadian intravenous drug users. International Journal of Std &","volume":"18","author":"E Roy","year":"2007","journal-title":"Aids"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1186\/1471-2458-9-270","article-title":"Unstable housing and hepatitis C incidence among injection drug users in a Canadian setting","volume":"9","author":"C Kim","year":"2009","journal-title":"BMC public health"},{"issue":"2","key":"ref11","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3109\/10826084.2015.1092991","article-title":"High prevalence and incidence of HIV and HCV among new injecting drug users with a large proportion of migrants\u2014is prevention failing?","volume":"51","author":"C Folch","year":"2016","journal-title":"Substance use & misuse"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/infdis\/jir196","article-title":"A systematic review and meta-analysis of interventions to prevent hepatitis C virus infection in people who inject drugs","volume":"204","author":"H Hagan","year":"2011","journal-title":"Journal of Infectious Diseases"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1186\/s12889-017-4210-2","article-title":"Effectiveness of needle and syringe Programmes in people who inject drugs\u2013An overview of systematic reviews","volume":"17","author":"RM Fernandes","year":"2017","journal-title":"BMC public health"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1023\/A:1014560431726","article-title":"Measures to reduce HIV infection have not been successful to reduce the prevalence of HCV in intravenous drug users","volume":"17","author":"I Hernandez-Aguado","year":"2001","journal-title":"European journal of epidemiology"},{"issue":"12","key":"ref15","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1001\/jamainternmed.2014.5416","article-title":"Association of opioid agonist therapy with lower incidence of hepatitis C virus infection in young adult injection drug users","volume":"174","author":"JI Tsui","year":"2014","journal-title":"JAMA internal medicine"},{"issue":"7","key":"ref16","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1093\/aje\/155.7.645","article-title":"Risk of hepatitis C virus infection among young adult injection drug users who share injection equipment","volume":"155","author":"LE Thorpe","year":"2002","journal-title":"American journal of epidemiology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1097\/01.aids.0000192091.38883.f9","article-title":"Provider assessment of eligibility for hepatitis C treatment in HIV-infected homeless and marginally housed persons","volume":"19","author":"VV Thompson","year":"2005","journal-title":"Aids"},{"issue":"17","key":"ref18","first-page":"453","article-title":"Increases in hepatitis C virus infection related to injection drug use among persons aged\u2264 30 years-Kentucky, Tennessee, Virginia, and West Virginia, 2006\u20132012","volume":"64","author":"JE Zibbell","year":"2015","journal-title":"MMWR Morbidity and mortality weekly report"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1097\/MEG.0000000000000843","article-title":"Hepatitis C in a Mobile Low-Threshold Methadone Program","volume":"29","author":"MJ Silva","year":"2017","journal-title":"European journal of gastroenterology & hepatology"},{"issue":"3","key":"ref20","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1159\/000220344","article-title":"Correlates of unsafe equipment sharing among injecting drug users in St. Petersburg, Russia","volume":"15","author":"VA Gyarmathy","year":"2009","journal-title":"European addiction research"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/eurpub\/ckp041","article-title":"Measuring risk of HIV and HCV among injecting drug users in the Russian Federation","volume":"19","author":"L Platt","year":"2009","journal-title":"The European Journal of Public Health"},{"issue":"12","key":"ref22","doi-asserted-by":"crossref","first-page":"e0143836","DOI":"10.1371\/journal.pone.0143836","article-title":"Are interferon-free direct-acting antivirals for the treatment of HCV enough to control the epidemic among people who inject drugs?","volume":"10","author":"VD Lima","year":"2015","journal-title":"PloS one"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"311","DOI":"10.4103\/0971-5916.166596","article-title":"Hepatitis C virus (HCV) infection & risk factors for HCV positivity in injecting & non-injecting drug users attending a de-addiction centre in northern India","volume":"142","author":"D Basu","year":"2015","journal-title":"The Indian journal of medical research"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s10461-014-0815-y","article-title":"Individual and socio-environmental factors associated with unsafe injection practices among young adult injection drug users","volume":"19","author":"F Mu\u00f1oz","year":"2015","journal-title":"San Diego. AIDS and Behavior"},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1086\/317607","article-title":"Hepatitis C virus infection: prevalence, risk factors, and prevention opportunities among young injection drug users in Chicago, 1997\u20131999","volume":"182","author":"LE Thorpe","year":"2000","journal-title":"The Journal of infectious diseases"},{"issue":"4","key":"ref26","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/01.qai.0000152398.47025.0f","article-title":"HIV incidence and factors contributed to retention in a 12-month follow-up study of injection drug users in Sichuan Province, China","volume":"39","author":"Y Ruan","year":"2005","journal-title":"JAIDS Journal of Acquired Immune Deficiency Syndromes"},{"issue":"suppl_2","key":"ref27","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1093\/cid\/cit271","article-title":"Models of care for the management of hepatitis C virus among people who inject drugs: one size does not fit all","volume":"57","author":"P Bruggmann","year":"2013","journal-title":"Clinical Infectious Diseases"},{"issue":"6","key":"ref28","doi-asserted-by":"crossref","first-page":"e97726","DOI":"10.1371\/journal.pone.0097726","article-title":"Declining incidence of hepatitis C virus infection among people who inject drugs in a Canadian setting, 1996\u20132012","volume":"9","author":"J Grebely","year":"2014","journal-title":"PloS one"},{"issue":"1","key":"ref29","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1186\/s12889-015-2442-6","article-title":"Cross sectional study of factors associated to self-reported blood-borne infections among drug users","volume":"15","author":"J Reyes-Urue\u00f1a","year":"2015","journal-title":"BMC public health"},{"issue":"20","key":"ref30","doi-asserted-by":"crossref","first-page":"3569","DOI":"10.3748\/wjg.v23.i20.3569","article-title":"Hepatitis C in injection drug users: It is time to treat","volume":"23","author":"A Grassi","year":"2017","journal-title":"World journal of gastroenterology"},{"issue":"6","key":"ref31","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1002\/hep.27403","article-title":"The impact of injecting networks on hepatitis C transmission and treatment in people who inject drugs","volume":"60","author":"M Hellard","year":"2014","journal-title":"Hepatology"},{"key":"ref32","article-title":"Impact of Hepatitis C treatment as prevention for people who inject drugs is sensitive to contact network","author":"C Metzig","journal-title":"Impact of Hepatitis C treatment as prevention for people who inject drugs is sensitive to contact network"},{"issue":"9","key":"ref33","doi-asserted-by":"crossref","first-page":"625","DOI":"10.7326\/M16-0816","article-title":"Elbasvir\u2013grazoprevir to treat hepatitis C virus infection in persons receiving opioid agonist therapy: a randomized trial","volume":"165","author":"GJ Dore","year":"2016","journal-title":"Annals of internal medicine"},{"issue":"1","key":"ref34","doi-asserted-by":"crossref","first-page":"S72","DOI":"10.1016\/S0168-8278(17)30406-3","article-title":"The PREVAIL study: intensive models of HCV care for people who inject drugs","volume":"66","author":"A Litwin","year":"2017","journal-title":"Journal of Hepatology"},{"issue":"3","key":"ref35","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s11904-017-0358-8","article-title":"HCV Cure and Reinfection Among People With HIV\/HCV Coinfection and People Who Inject Drugs","volume":"14","author":"M Martinello","year":"2017","journal-title":"Current HIV\/AIDS Reports"},{"issue":"3","key":"ref36","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1002\/hep.26164","article-title":"Sexual transmission of hepatitis C virus among monogamous heterosexual couples: the HCV partners study","volume":"57","author":"NA Terrault","year":"2013","journal-title":"Hepatology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0204795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T14:12:13Z","timestamp":1540217533000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0204795"}},"subtitle":[],"editor":[{"given":"Jason","family":"Blackard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,10,3]]},"references-count":36,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,10,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0204795","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,3]]}}}