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Studies in paleopathology. I. General consideration of the evidences of pathological conditions found among fossil animals. Paul B. Hoeber; 1918. pp. 374\u2013393.","DOI":"10.5962\/bhl.title.13893"},{"key":"ref8","unstructured":"Rothschild B, Martin LD. Skeletal Impact of Disease. New Mexico Museum of Natural History and Science Bulletin N\u00b0 33; 2006. p. 187."},{"key":"ref9","first-page":"1","article-title":"Ichthyosaurian palaeopathology: Evidence of injury and disease in fossil \u201cfish lizards\u201d","author":"JM Pardo-P\u00e9rez","year":"2017","journal-title":"Journal of Zoology"},{"key":"ref10","first-page":"108","article-title":"\u00dcber zwei F\u00e4lle von Nearthrose bei fossilen Ichthyosauriern","volume":"70","author":"F von Huene","year":"1930","journal-title":"Anatomischer Anzeiger"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/45435","article-title":"Large eyeballs in diving ichthyosaurs","volume":"402","author":"R Motani","year":"1999","journal-title":"Nature"},{"key":"ref12","first-page":"21","article-title":"Nuevo material de <italic>Caypullisaurus bonapartei<\/italic> Fern\u00e1ndez (Reptilia: Ichthyosauridae) del Jur\u00e1sico Superior de la Cuenca Neuquina, Argentina","volume":"35","author":"MS Fern\u00e1ndez","year":"1998","journal-title":"Ameghiniana"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.palaeo.2015.11.049","article-title":"Evidence of a preservational gradient in the skeletal taphonomy of Ichthyopterygia (Reptilia) from Europe","volume":"443","author":"SR Beardmore","year":"2016","journal-title":"Palaeogeography, Palaeoclimatology, Palaeoecology"},{"key":"ref14","first-page":"70","article-title":"Gro\u00dfe Wirbeltierfunde aus der Grube Mistelgau","volume":"15","author":"JM Rabold","year":"2013","journal-title":"Der Steinkern"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1017\/S0016774600021119","article-title":"Sharks eating mosasaurs, dead or alive?","volume":"84","author":"BM Rothschild","year":"2005","journal-title":"Netherlands Journal of Geosciences"},{"key":"ref16","unstructured":"von Huene F. Neue Ichthyosaurier aus W\u00fcrttemberg. Neues Jahrbuch f\u00fcr Mineralogie Geologie und Pal\u00e4ontologie Beilage-Band 65, Abteilung B. 1931; 305\u2013320."},{"key":"ref17","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1111\/j.1475-4983.2012.01151.x","article-title":"Cranial anatomy, taxonomic implications and palaeopathology of an Upper Jurassic pliosaur (Reptilia: Sauropterygia) from Westbury, Wiltshire, UK","volume":"55","author":"J Sassoon","year":"2012","journal-title":"Palaeontology"},{"key":"ref18","article-title":"Bony outgrowths on the jaws of an extinct sperm whale support macroraptorial feeding in several stem physeteroids","author":"O Lambert","year":"2014","journal-title":"The Science of Nature"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3354\/dao02339","article-title":"Dental pathology in dolphins (Cetacea: Delphinidae) from the southern coast of Brazil","volume":"94","author":"C Loch","year":"2011","journal-title":"Diseases of Aquatic Organisms"},{"key":"ref20","first-page":"13","article-title":"Descripci\u00f3n y evaluaci\u00f3n anat\u00f3mica de lesiones \u00f3seas cr\u00e1neo-mandibulares en cet\u00e1ceos odontocetos del mar peruano","volume":"15","author":"D Montes","year":"2004","journal-title":"Revista de Investigaciones Veterinarias del Per\u00fa"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"533","DOI":"10.2460\/javma.1975.167.07.533","article-title":"Common diseases of small cetaceans","author":"JC Sweeney","year":"1975","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1080\/03115510108619228","article-title":"Dental caries in an Early Cretaceous ichthyosaur","volume":"25","author":"BP Kear","year":"2001","journal-title":"Alcheringa"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"859","DOI":"10.4202\/app.2010.0117","article-title":"Healed bite marks on a Cretaceous ichthyosaur","volume":"56","author":"M Zammit","year":"2011","journal-title":"Acta Palaeontologica Polonica"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms10825","article-title":"Extinction of fish.shaped marine reptiles associated with reduced evolutionary rates and global environmental volatility","volume":"7","author":"V Fischer","year":"2016","journal-title":"Nature Communications"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1098\/rsbl.2003.0050","article-title":"Unusual gut contents in a Cretaceous ichthyosaur","volume":"270","author":"BP Kear","year":"2003","journal-title":"Proceedings of the Royal Society"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/02724634.1987.10011647","article-title":"Tooth morphology and prey preference of Mesozoic marine reptiles","volume":"7","author":"J Massare","year":"1987","journal-title":"Journal of Vertebrate Paleontology"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1671\/0272-4634(2003)23[116:TCOOTI]2.0.CO;2","article-title":"The cranial osteology of the ichthyosaur <italic>Leptonectes<\/italic> cf. <italic>tenuirostris<\/italic> from the Lower Jurassic of England","volume":"23","author":"MW Maisch","year":"2003","journal-title":"Journal of Vertebrate Paleontology"},{"key":"ref28","first-page":"139","article-title":"Large ichthyosaurs from the Upper Triassic of Nevada","volume":"170","author":"CL Camp","year":"1980","journal-title":"Paleontographica Abteilung A"},{"key":"ref29","first-page":"345","article-title":"Neue Studien \u00fcber Ichthyosaurier aus Holzmaden","volume":"42","author":"F von Huene","year":"1931","journal-title":"Abhandlungen Senckenbergische Naturforschende Gessellschaft"},{"key":"ref30","first-page":"277","article-title":"Ein neuer Fund von <italic>Eurhinosaurus longirostris<\/italic>","volume":"93","author":"F von Huene","year":"1951","journal-title":"Neues Jahrbuch f\u00fcr Geologie und Palaontologie, Abhandlungen Band 93, H 2"},{"key":"ref31","unstructured":"Keller T. Traumatische Skelettfrakturen als Anzeiger der Lebensweise gro\u00dfer Ichthyosaurier des Unterjura S\u00fcddeutschlands. Lesebuch f\u00fcr Querdenker. Gesellschaft zur F\u00f6rderung arbeitsorientierter Forschung und Bildung; 2006. pp. 251\u2013269."},{"key":"ref32","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00114-012-0918-0","article-title":"Adaptations for marine habitat and the effect of Triassic and Jurassic predator pressure on development of decompression syndrome in ichthyosaurs","volume":"99","author":"BM Rothschild","year":"2012","journal-title":"Naturwissenschaften"},{"key":"ref33","first-page":"2","article-title":"Pre- and postmortem tyrannosaurid bite marks on the remains of <italic>Daspletosaurus<\/italic> (Tyrannosaurinae: Theropoda) from Dinosaur Provincial Park, Alberta, Canada","author":"D Hone","year":"2015","journal-title":"PeerJ"},{"key":"ref34","first-page":"167","article-title":"Head-biting behavior in theropod dinosaurs: Paleopathological evidence","volume":"184","author":"DH Tanke","year":"1998","journal-title":"Gaia Ecological Perspectives for Science and Society"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.1502-3931.2009.00195.x","article-title":"A tyrannosaur jaw bitten by a confamilial: Scavenging or fatal agonism?","volume":"43","author":"PR Bell","year":"2010","journal-title":"Lethaia"},{"key":"ref36","first-page":"644","article-title":"Vorzeitliche Lebensspuren","author":"O Abel","year":"1935"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1748-7692.2009.00334.x","article-title":"Mandibular fractures in short-finned pilot whales, <italic>Globicephala macrorhynchus<\/italic>","volume":"26","author":"MS Oremland","year":"2010","journal-title":"Marine Mammal Science"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/B978-012415031-7\/50028-8","article-title":"White shark predation and scavenging on cetaceans in the eastern north Pacific Ocean","author":"DJ Long","year":"1996","journal-title":"Great White Sharks"},{"key":"ref39","unstructured":"Clarke R, Paliza O. Intraspecific figthing in Sperm Whales. Report of the International Whaling Commission. 1988; 235\u2013241."},{"key":"ref40","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1660\/0022-8443-111.3.251","article-title":"A bitten skull of <italic>Tylosaurus kansasensis<\/italic> (Squamata: Mosasauridae) and a review of mosasaur-on-mosasaur pathology in the fossil record","volume":"111","author":"MJ Everhart","year":"2008","journal-title":"Transactions of the Kansas Academy of Science"},{"key":"ref41","article-title":"Paleopathology: disease in the fossil record","author":"B.M. R","year":"1993"},{"key":"ref42","first-page":"18A","article-title":"Direct evidence of aggressive intraspecific competition in <italic>Mosasaurus conodon<\/italic> (Mosasauridae: Squamata)","volume":"15","author":"GL Bell","year":"1995","journal-title":"Journal of Vertebrate Paleontology"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1502-3931.1998.tb00520.x","article-title":"Unusual death of a Cretaceous giant","volume":"31","author":"T Lingham-Soliar","year":"1998","journal-title":"Lethaia"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1080\/00241160410006519","article-title":"Palaeopathology and injury in the extinct mosasaurs (Lepidosauromorpha, Squamata) and implications for modern reptiles","volume":"37","author":"T Lingham-Soliar","year":"2004","journal-title":"Lethaia"},{"key":"ref45","first-page":"41","article-title":"Chronic bone infection in the jaw of <italic>Mosasaurus hoffmanni<\/italic> (Squamata)","volume":"6","author":"AS Schulp","year":"2006","journal-title":"Oryctos"},{"key":"ref46","first-page":"91","article-title":"Studies in Paleopathology: XX. Vertebral lesions in the sabre-tooth, Pleistocene of California, resembling the so-called Myositis Ossificans Progressiva, compared with certain ossifications in the dinosaurs","volume":"9","author":"RL Moodie","year":"1927","journal-title":"Annals of Medical History"},{"key":"ref47","first-page":"99","article-title":"Considerations on the comparative pathology of the vertebrae in Mysticeti and Odontoceti ; evidence for the occurrence of discarthrosis zygarthrosis, infectious spondylitis and spondyloarthritis","volume":"5","author":"EJO Kompanje","year":"1999","journal-title":"Zool Med Leiden"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3354\/dao075259","article-title":"Spondylitis in a humpback whale (<italic>Megaptera novaeangliae<\/italic>) from the southeast Pacific","volume":"75","author":"F F\u00e9lix","year":"2007","journal-title":"Diseases of aquatic organisms"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1126\/science.48.1251.619-a","article-title":"Synthesis of paleontology and medical history","volume":"48","author":"RL Moodie","year":"1918","journal-title":"Science"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1126\/science.236.4797.75","article-title":"Avascular Necrosis: Occurrence in diving Cretaceous Mosasaurs","volume":"236","author":"B Rothschild","year":"1987","journal-title":"Science"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1671\/0272-4634(2001)021[0253:PSPTFF]2.0.CO;2","article-title":"Plesiosaur spinal pathology: the first fossil occurrence of Schmorl\u2019s nodes","volume":"21","author":"PJ Hopley","year":"2001","journal-title":"Journal of Vertebrate Paleontology"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1660\/062.118.0309","article-title":"Co-ossification of vertebrae in mosasaurs (Squamata, Mosasauridae); Evidence of habitat interactions and susceptibility to bone disease","volume":"118","author":"B Rothschild","year":"2015","journal-title":"Transactions of the Kansas Academy of Science"},{"key":"ref53","first-page":"242","article-title":"Vertebral morphology of <italic>Ophthalmosaurus natans<\/italic> (Reptilia: Ichthyosauria) from the Jurassic Sundance Formation of Wyoming","volume":"5","author":"JA Massare","year":"2006","journal-title":"Paludicola"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0204951","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T21:32:00Z","timestamp":1775251920000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0204951"}},"subtitle":[],"editor":[{"given":"Ulrich","family":"Joger","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,10,24]]},"references-count":53,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,10,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0204951","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,24]]}}}