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Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.fda.gov\/food\/ingredientspackaginglabeling\/gras\/scogs\/default.htm\" xlink:type=\"simple\">https:\/\/www.fda.gov\/food\/ingredientspackaginglabeling\/gras\/scogs\/default.htm<\/ext-link> Cited 15 Sep 2018"},{"issue":"2","key":"ref23","first-page":"105","article-title":"Is broiler breeder welfare improved by using qualitative rather than quantitative food restriction to limit growth rate? 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The effect of alternative feeding strategies for broiler breeder pullets throughout the production cycle. Doctoral Thesis, University of Guelph. 2018. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/atrium.lib.uoguelph.ca\/xmlui\/handle\/10214\/14347\" xlink:type=\"simple\">https:\/\/atrium.lib.uoguelph.ca\/xmlui\/handle\/10214\/14347<\/ext-link>"},{"issue":"4","key":"ref40","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1017\/S0962728600003110","article-title":"Too hungry to learn? Hungry broiler breeders fail to learn a Y-maze food quantity discrimination task","volume":"20","author":"LA Buckley","year":"2011","journal-title":"Anim Welf"},{"issue":"4","key":"ref41","doi-asserted-by":"crossref","first-page":"447","DOI":"10.7120\/09627286.24.4.447","article-title":"Slow and steady wins the race? 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