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An operational manual, http:\/\/www.who.int\/malaria\/publications\/atoz\/9789241505604\/en\/<\/ext-link> (last access: 14th January 2019). 2013."},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1016\/S2542-5196(18)30010-X","article-title":"Rapid improvements to rural Ugandan housing and their association with malaria from intense to reduced transmission: a cohort study","volume":"2","author":"JC Rek","year":"2018","journal-title":"The Lancet Planetary Health"},{"key":"ref5","unstructured":"World Health Organization, Global Technical Strategy for Malaria 2016\u20132030, http:\/\/www.who.int\/malaria\/areas\/global_technical_strategy\/en\/<\/ext-link> (last access: 14th January 2019). 2015."},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/1756-3305-6-172","article-title":"Eliminating malaria vectors","volume":"6","author":"GF Killeen","year":"2013","journal-title":"Parasite Vector"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/jee\/53.1.134","article-title":"The Designation of Chemicals in Terms of the Responses They Elicit from Insects1","volume":"53","author":"VG Dethier","year":"1960","journal-title":"J Econ Entomol"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"e716","DOI":"10.1371\/journal.pone.0000716","article-title":"A New Classification System for the Actions of IRS Chemicals Traditionally Used For Malaria Control","volume":"2","author":"JP Grieco","year":"2007","journal-title":"Plos One"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1017\/S0007485300003424","article-title":"A verandah-trap hut for studying the house-frequenting habits of mosquitoes and for assessing insecticides. 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The effect of tetramethrin on the behaviour and mortality of Anopheles gambiae<\/italic> Giles","volume":"59","author":"A Smith","year":"1969","journal-title":"B Entomol Res"},{"key":"ref10","article-title":"Insect repellents, Principles, Methods and Uses","author":"GB White","year":"2007"},{"key":"ref11","unstructured":"World Health Organization, Guidelines for laboratory and field testing of mosquito larvicides, http:\/\/apps.who.int\/iris\/handle\/10665\/69101<\/ext-link> (last access: 14th January 2019). 2005."},{"key":"ref12","unstructured":"World Health Organization, Guidelines for testing mosquito adulticides for indoor residual spraying and treatment of mosquito nets, http:\/\/www.who.int\/whopes\/resources\/who_cds_ntd_whopes_gcdpp_2006.3\/en\/<\/ext-link> (last access: 14th January 2019). 2006."},{"issue":"2","key":"ref13","first-page":"159","article-title":"Simplification of adult mosquito bioassays through use of time-mortality determinations in glass 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Alder","year":"2006","journal-title":"Mass Spectrom Rev"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.chroma.2014.06.104","article-title":"Use of ammonium formate in QuEChERS for high-throughput analysis of pesticides in food by fast, low-pressure gas chromatography and liquid chromatography tandem mass spectrometry","volume":"1358","author":"M\u00c1 Gonz\u00e1lez-Curbelo","year":"2014","journal-title":"J Chrom A"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.foodchem.2014.07.102","article-title":"Multiresidue analysis of over 200 pesticides in cereals using a QuEChERS and gas chromatography\u2013tandem mass spectrometry-based method","volume":"169","author":"Z He","year":"2015","journal-title":"Food Chem"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.aca.2016.07.023","article-title":"Determination of pesticides and veterinary drug residues in food by liquid chromatography-mass 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(SANTE\/11813\/2017). 2017."},{"key":"ref26","unstructured":"Pesticide Properties DataBase (PPDB), University of Hertfordshire https:\/\/sitem.herts.ac.uk\/aeru\/ppdb\/<\/ext-link> (last time accessed 29th May 2018)."},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"e94482","DOI":"10.1371\/journal.pone.0094482","article-title":"Pesticide Residues and Bees\u2014A Risk Assessment","volume":"9","author":"F Sanchez-Bayo","year":"2014","journal-title":"Plos One"},{"issue":"16","key":"ref28","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/rcm.6962","article-title":"Mass accuracy improvement of reversed-phase liquid chromatography\/electrospray ionization mass spectrometry based urinary metabolomic analysis by post-run calibration using sodium formate cluster ions","volume":"28","author":"CG Juo","year":"2014","journal-title":"Rapid Commun Mass Sp"},{"key":"ref29","unstructured":"World Health Organization, Test procedures for insecticide resistance monitoring in malaria vector mosquitoes, 2nd ed, http:\/\/apps.who.int\/iris\/handle\/10665\/250677<\/ext-link> (last access: 14th January 2019). 2016."},{"key":"ref30","article-title":"Probit analysis","author":"DJ Finney","year":"1971"},{"key":"ref31","unstructured":"Raymond M, Prato G, D. R. Probit and logit analysis program, version 2.0. Praxe`me, Biometric, Centre National de la Recherche Scienti\u00deque, Montpellier, France. 1997."},{"key":"ref32","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0021-9673(01)83520-2","article-title":"Gas chromatography of deuterated and protiated chloro derivatives of 1,4-dimethylbenzene","volume":"351","author":"J Bermejo","year":"1986","journal-title":"J Chrom A"},{"key":"ref33","unstructured":"DIN Deutsches Institut f\u00fcr Normung e.V., DIN 38402\u201351: German standard methods for the examination of water, waste water and sludge; general information (group A); calibration of analytical methods, evaluation of analytical results and linear calibration functions used to determine the performance characteristics of analytical methods (A 51)."},{"key":"ref34","unstructured":"World Health Organization, Guidelines for monitoring the durability of long-lasting insecticidal mosquito nets under operational conditions, https:\/\/www.who.int\/malaria\/publications\/atoz\/9789241501705\/en\/<\/ext-link> (last access: 14th January 2019). 2011."},{"key":"ref35","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.ultsonch.2016.06.035","article-title":"Ultrasound assisted extraction of food and natural products. 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(Culicidae: Giles) from selected in-land and coastal agricultural areas of Ghana","volume":"5","author":"GG Nutifafa","year":"2017","journal-title":"Journal of Entomology and Zoology Studies"},{"key":"ref38","doi-asserted-by":"crossref","DOI":"10.1186\/1475-2875-13-350","article-title":"Environmental temperatures significantly change the impact of insecticides measured using WHOPES protocols","volume":"13","author":"KD Glunt","year":"2014","journal-title":"Malaria J"},{"issue":"3","key":"ref39","doi-asserted-by":"crossref","first-page":"e58322","DOI":"10.1371\/journal.pone.0058322","article-title":"Effects of Age and Larval Nutrition on Phenotypic Expression of Insecticide-Resistance in Anopheles Mosquitoes","volume":"8","author":"K Kulma","year":"2013","journal-title":"Plos One"},{"key":"ref40","doi-asserted-by":"crossref","DOI":"10.1186\/1756-3305-7-390","article-title":"The effect of multiple blood-feeding on the longevity and insecticide resistant phenotype in the major malaria vector Anopheles arabiensis<\/italic> (Diptera: Culicidae)","volume":"7","author":"SV Oliver","year":"2014","journal-title":"Parasite Vector"},{"issue":"32","key":"ref41","doi-asserted-by":"crossref","first-page":"8975","DOI":"10.1073\/pnas.1603431113","article-title":"Delayed mortality effects cut the malaria transmission potential of insecticide-resistant mosquitoes","volume":"113","author":"M Viana","year":"2016","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"ref42","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1002\/ps.2780070612","article-title":"The mode of action of insecticides: Accelerated water loss and reduced respiration in insecticide-treated Musca domestica<\/italic> L","volume":"7","author":"P Gerolt","year":"1976","journal-title":"Pestic Sci"},{"issue":"2","key":"ref43","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.pestbp.2012.12.004","article-title":"Effects of permethrin and amitraz on gas exchange and water loss in unfed adult females of Amblyomma americanum<\/italic> (Acari: Ixodidae)","volume":"107","author":"H Zheng","year":"2013","journal-title":"Pestic Biocid Phys"},{"issue":"10","key":"ref44","doi-asserted-by":"crossref","first-page":"e0139841","DOI":"10.1371\/journal.pone.0139841","article-title":"Genetics, Synergists, and Age Affect Insecticide Sensitivity of the Honey Bee, Apis mellifera<\/italic>","volume":"10","author":"FD Rinkevich","year":"2015","journal-title":"Plos One"},{"issue":"1","key":"ref45","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/BF00175458","article-title":"Honey bee foragers as sensory units of their colonies","volume":"34","author":"TD Seeley","year":"1994","journal-title":"Behav Ecol Sociobiol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0211064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T19:47:21Z","timestamp":1588967241000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0211064"}},"subtitle":[],"editor":[{"given":"Pedro L.","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,2,7]]},"references-count":45,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,2,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0211064","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,7]]}}}