{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:00:15Z","timestamp":1792000815829,"version":"4.4.0"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T00:00:00Z","timestamp":1554336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01-AI35042"],"award-info":[{"award-number":["U01-AI35042"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01-AI35039"],"award-info":[{"award-number":["U01-AI35039"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01-AI35040"],"award-info":[{"award-number":["U01-AI35040"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01-AI35041"],"award-info":[{"award-number":["U01-AI35041"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["UM1-AI35043"],"award-info":[{"award-number":["UM1-AI35043"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL095129"],"award-info":[{"award-number":["R01 HL095129"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0214735","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T17:34:37Z","timestamp":1554399277000},"page":"e0214735","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":56,"title":["Inflammatory biomarkers and subclinical carotid atherosclerosis in HIV-infected and HIV-uninfected men in the Multicenter AIDS Cohort Study"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1059-0847","authenticated-orcid":true,"given":"Vinita","family":"Subramanya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather S.","family":"McKay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebeccah M.","family":"Brusca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank J.","family":"Palella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence A.","family":"Kingsley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallory D.","family":"Witt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard N.","family":"Hodis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell P.","family":"Tracy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy S.","family":"Post","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9467-3454","authenticated-orcid":true,"given":"Sabina A.","family":"Haberlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,4,4]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/cid\/civ325","article-title":"HIV Infection Is Associated With Progression of Subclinical Carotid Atherosclerosis","volume":"61","author":"DB Hanna","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"9","key":"ref2","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1097\/QAD.0b013e32832b514b","article-title":"Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis","volume":"23","author":"PY Hsue","year":"2009","journal-title":"Aids"},{"issue":"18","key":"ref3","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1097\/QAD.0b013e32835a9950","article-title":"Increased coronary atherosclerosis and immune activation in HIV-1 elite controllers","volume":"26","author":"F Pereyra","year":"2012","journal-title":"Aids"},{"issue":"8","key":"ref4","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1001\/jamainternmed.2013.3728","article-title":"HIV infection and the risk of acute myocardial infarction","volume":"173","author":"MS Freiberg","year":"2013","journal-title":"JAMA internal medicine"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/QAI.0b013e3181a9992c","article-title":"Association of C-reactive protein and HIV infection with acute myocardial infarction","volume":"51","author":"VA Triant","year":"2009","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"7","key":"ref6","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1210\/jc.2006-2190","article-title":"Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus disease","volume":"92","author":"VA Triant","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"28741","DOI":"10.1038\/srep28741","article-title":"Urinary albumin-to-creatinine ratio is associated with endothelial dysfunction in HIV-infected patients receiving antiretroviral therapy","volume":"6","author":"M Pirro","year":"2016","journal-title":"Sci Rep"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.atherosclerosis.2018.03.031","article-title":"Elevated serum uric acid levels are associated with endothelial dysfunction in HIV patients receiving highly-active antiretroviral therapy","volume":"272","author":"M Pirro","year":"2018","journal-title":"Atherosclerosis"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/QAI.0b013e3181e66216","article-title":"Inflammation and mortality in HIV-infected adults: analysis of the FRAM study cohort","volume":"55","author":"PC Tien","year":"2010","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"e000422","DOI":"10.1161\/JAHA.111.000422","article-title":"Carotid intima-media thickness progression in HIV-infected adults occurs preferentially at the carotid bifurcation and is predicted by inflammation","volume":"1","author":"PY Hsue","year":"2012","journal-title":"Journal of the American Heart Association"},{"issue":"10","key":"ref11","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1097\/QAD.0b013e32833ad914","article-title":"Traditional risk factors and D-dimer predict incident cardiovascular disease events in chronic HIV infection","volume":"24","author":"ES Ford","year":"2010","journal-title":"Aids"},{"issue":"8","key":"ref12","doi-asserted-by":"crossref","first-page":"C7","DOI":"10.1016\/j.jacc.2005.09.068","article-title":"Pathogenesis of atherosclerosis","volume":"47","author":"E. Falk","year":"2006","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"e0169986","DOI":"10.1371\/journal.pone.0169986","article-title":"Association between Immune Markers and Surrogate Markers of Cardiovascular Disease in HIV Positive Patients: A Systematic Review","volume":"12","author":"AG Vos","year":"2017","journal-title":"PLoS One"},{"issue":"1","key":"ref14","doi-asserted-by":"crossref","first-page":"e0147484","DOI":"10.1371\/journal.pone.0147484","article-title":"Pro-Inflammatory Markers in Relation to Cardiovascular Disease in HIV Infection. A Systematic Review","volume":"11","author":"AG Vos","year":"2016","journal-title":"PLoS One"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1186\/1471-2334-13-414","article-title":"The association of high-sensitivity c-reactive protein and other biomarkers with cardiovascular disease in patients treated for HIV: a nested case-control study","volume":"13","author":"A De Luca","year":"2013","journal-title":"BMC Infect Dis"},{"issue":"9","key":"ref16","doi-asserted-by":"crossref","first-page":"e44454","DOI":"10.1371\/journal.pone.0044454","article-title":"Inflammation, coagulation and cardiovascular disease in HIV-infected individuals","volume":"7","author":"DA Duprez","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"ref17","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/COH.0000000000000227","article-title":"Immune activation and cardiovascular disease in chronic HIV infection","volume":"11","author":"CT Longenecker","year":"2016","journal-title":"Current opinion in HIV and AIDS"},{"issue":"8","key":"ref18","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1093\/infdis\/jiu594","article-title":"Elevated levels of monocyte activation markers are associated with subclinical atherosclerosis in men with and those without HIV infection","volume":"211","author":"RA McKibben","year":"2015","journal-title":"J Infect Dis"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.003371","article-title":"Inflammatory Markers Associated With Subclinical Coronary Artery Disease: The Multicenter AIDS Cohort Study","volume":"5","author":"H Bahrami","year":"2016","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"ref20","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/aje\/126.2.310","article-title":"The Multicenter AIDS Cohort Study: rationale, organization, and selected characteristics of the participants","volume":"126","author":"RA Kaslow","year":"1987","journal-title":"Am J Epidemiol"},{"issue":"3","key":"ref21","first-page":"207","article-title":"Use of cardiac CT angiography imaging in an epidemiology study\u2014the Methodology of the Multicenter AIDS Cohort Study cardiovascular disease substudy","volume":"13","author":"Y Hacioglu","year":"2013","journal-title":"Anadolu kardiyoloji dergisi: AKD = the Anatolian journal of cardiology"},{"issue":"7","key":"ref22","doi-asserted-by":"crossref","first-page":"458","DOI":"10.7326\/M13-1754","article-title":"Associations between HIV infection and subclinical coronary atherosclerosis","volume":"160","author":"WS Post","year":"2014","journal-title":"Annals of internal medicine"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Touboul PJ, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, et al. Mannheim carotid intima-media thickness and plaque consensus (2004-2006-2011). An update on behalf of the advisory board of the 3rd, 4th and 5th watching the risk symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011. Cerebrovascular diseases (Basel, Switzerland). 2012;34(4):290\u20136. Epub 2012\/11\/07. <comment>doi: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/doi.org\/10.1159\/000343145\" xlink:type=\"simple\">10.1159\/000343145<\/ext-link><\/comment>","DOI":"10.1159\/000343145"},{"issue":"1","key":"ref24","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0021-9150(00)00461-5","article-title":"Improved common carotid elasticity and intima-media thickness measurements from computer analysis of sequential ultrasound frames","volume":"154","author":"RH Selzer","year":"2001","journal-title":"Atherosclerosis"},{"issue":"13","key":"ref25","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1097\/QAD.0b013e328300581d","article-title":"Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men","volume":"22","author":"RC Kaplan","year":"2008","journal-title":"Aids"},{"issue":"2","key":"ref26","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0090-1229(90)90096-9","article-title":"Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience. The Multicenter AIDS Cohort Study Group","volume":"55","author":"JV Giorgi","year":"1990","journal-title":"Clinical immunology and immunopathology"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s11883-009-0021-y","article-title":"Monocyte chemoattractant protein-1\/CCL2 as a biomarker in acute coronary syndromes","volume":"11","author":"C Gonzalez-Quesada","year":"2009","journal-title":"Curr Atheroscler Rep"},{"issue":"15","key":"ref28","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1161\/01.CIR.0000143835.95029.7D","article-title":"Atherosclerosis in patients infected with HIV is influenced by a mutant monocyte chemoattractant protein-1 allele","volume":"110","author":"C Alonso-Villaverde","year":"2004","journal-title":"Circulation"},{"issue":"1\u20132","key":"ref29","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cca.2005.12.014","article-title":"The influence of HIV infection on the correlation between plasma concentrations of monocyte chemoattractant protein-1 and carotid atherosclerosis","volume":"368","author":"J Joven","year":"2006","journal-title":"Clinica chimica acta; international journal of clinical chemistry"},{"issue":"1\u20132","key":"ref30","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.cyto.2006.03.013","article-title":"HIV-infected patients with lipodystrophy have higher rates of carotid atherosclerosis: the role of monocyte chemoattractant protein-1","volume":"34","author":"B Coll","year":"2006","journal-title":"Cytokine"},{"issue":"8","key":"ref31","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1097\/QAD.0b013e328329c76b","article-title":"Association of HIV viral load with monocyte chemoattractant protein-1 and atherosclerosis burden measured by magnetic resonance imaging","volume":"23","author":"M Floris-Moore","year":"2009","journal-title":"Aids"},{"issue":"9","key":"ref32","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1291\/hypres.26.677","article-title":"Polymorphism of the monocyte chemoattractant protein (MCP-1) gene is associated with the plasma level of MCP-1 but not with carotid intima-media thickness","volume":"26","author":"Y Tabara","year":"2003","journal-title":"Hypertension research: official journal of the Japanese Society of Hypertension"},{"issue":"8","key":"ref33","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1093\/infdis\/jir520","article-title":"Soluble CD163, a novel marker of activated macrophages, is elevated and associated with noncalcified coronary plaque in HIV-infected patients","volume":"204","author":"TH Burdo","year":"2011","journal-title":"J Infect Dis"},{"issue":"6","key":"ref34","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1161\/ATVBAHA.110.203364","article-title":"Peripheral artery disease is associated with a high CD163\/TWEAK plasma ratio","volume":"30","author":"JA Moreno","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"2","key":"ref35","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.atherosclerosis.2011.09.016","article-title":"Impact of soluble TWEAK and CD163\/TWEAK ratio on long-term cardiovascular mortality in patients with peripheral arterial disease","volume":"219","author":"G Urbonaviciene","year":"2011","journal-title":"Atherosclerosis"},{"issue":"9","key":"ref36","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1093\/infdis\/jix082","article-title":"Association of macrophage inflammation biomarkers with progression of subclinical carotid artery atherosclerosis in HIV-infected women and men","volume":"215","author":"DB Hanna","year":"2017","journal-title":"The Journal of infectious diseases"},{"issue":"4","key":"ref37","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1001\/jama.2012.6698","article-title":"Arterial inflammation in patients with HIV","volume":"308","author":"S Subramanian","year":"2012","journal-title":"Jama"},{"issue":"1","key":"ref38","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/QAD.0b013e328358b29c","article-title":"Effects of aging and smoking on carotid intima-media thickness in HIV-infection","volume":"27","author":"KV Fitch","year":"2013","journal-title":"Aids"},{"issue":"2","key":"ref39","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/QAD.0b013e328333ea9e","article-title":"Increased prevalence of subclinical coronary atherosclerosis detected by coronary computed tomography angiography in HIV-infected men","volume":"24","author":"J Lo","year":"2010","journal-title":"Aids"},{"issue":"1","key":"ref40","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1172\/JCI29950","article-title":"Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata","volume":"117","author":"FK Swirski","year":"2007","journal-title":"The Journal of clinical investigation"},{"issue":"9","key":"ref41","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1093\/infdis\/jix085","article-title":"Macrophage Inflammation and Cardiovascular Disease in HIV: Mechanistic Insights and Future Directions","volume":"215","author":"MJ Feinstein","year":"2017","journal-title":"J Infect Dis"},{"issue":"13","key":"ref42","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1161\/01.CIR.0000124480.32233.8A","article-title":"Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection","volume":"109","author":"PY Hsue","year":"2004","journal-title":"Circulation"},{"issue":"13","key":"ref43","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1097\/QAD.0000000000001149","article-title":"Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy","volume":"30","author":"DC Hsu","year":"2016","journal-title":"Aids"},{"issue":"7","key":"ref44","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/0092-8674(93)90367-Y","article-title":"Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1-dependent pathway","volume":"73","author":"LR Languino","year":"1993","journal-title":"Cell"},{"issue":"12","key":"ref45","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1093\/oxfordjournals.aje.a116821","article-title":"Plasma fibrinogen: levels and correlates in young adults. The Coronary Artery Risk Development in Young Adults (CARDIA) Study","volume":"138","author":"AR Folsom","year":"1993","journal-title":"Am J Epidemiol"},{"issue":"1","key":"ref46","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/07853890701645399","article-title":"Carotid intima-media thickness and markers of inflammation, endothelial damage and hemostasis","volume":"40","author":"D Baldassarre","year":"2008","journal-title":"Annals of medicine"},{"issue":"2","key":"ref47","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.atherosclerosis.2008.05.039","article-title":"Elevated fibrinogen levels and subsequent subclinical atherosclerosis: the CARDIA Study","volume":"202","author":"D Green","year":"2009","journal-title":"Atherosclerosis"},{"issue":"9","key":"ref48","first-page":"2167","article-title":",","volume":"20","author":"LF Bielak","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"6","key":"ref49","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1097\/01.hjh.0000226198.44181.0c","article-title":"Interleukin 6 is associated with subclinical atherosclerosis: a link with soluble intercellular adhesion molecule 1","volume":"24","author":"J Amar","year":"2006","journal-title":"Journal of hypertension"},{"issue":"2","key":"ref50","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0021-9150(02)00071-0","article-title":"Soluble intercellular adhesion molecule-1 is associated with carotid and femoral atherosclerosis but not with intima-media thickness in a population-based sample","volume":"164","author":"V Bongard","year":"2002","journal-title":"Atherosclerosis"},{"issue":"2","key":"ref51","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1373\/clinchem.2011.168559","article-title":"Circulating soluble intercellular adhesion molecule 1 and subclinical atherosclerosis: the Coronary Artery Risk Development in Young Adults Study","volume":"58","author":"MD Gross","year":"2012","journal-title":"Clin Chem"},{"issue":"11","key":"ref52","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1161\/01.ATV.18.11.1765","article-title":"Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosis","volume":"18","author":"LE Rohde","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"1","key":"ref53","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.atherosclerosis.2004.09.018","article-title":"Associations of soluble intercellular adhesion molecule-1 with carotid atherosclerosis progression","volume":"179","author":"K Kondo","year":"2005","journal-title":"Atherosclerosis"},{"issue":"1","key":"ref54","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1093\/ndt\/18.1.113","article-title":"Carotid atherosclerosis is associated with inflammation and endothelial cell adhesion molecules in chronic haemodialysis patients","volume":"18","author":"A Papagianni","year":"2003","journal-title":"Nephrology Dialysis Transplantation"},{"issue":"4","key":"ref55","doi-asserted-by":"crossref","first-page":"e000264","DOI":"10.1161\/JAHA.113.000264","article-title":"HIV replication alters the composition of extrinsic pathway coagulation factors and increases thrombin generation","volume":"2","author":"JV Baker","year":"2013","journal-title":"J Am Heart Assoc"},{"issue":"4","key":"ref56","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.immuni.2013.10.001","article-title":"Systemic effects of inflammation on health during chronic HIV infection","volume":"39","author":"SG Deeks","year":"2013","journal-title":"Immunity"},{"issue":"12","key":"ref57","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1056\/NEJMoa1707914","article-title":"Antiinflammatory therapy with canakinumab for atherosclerotic disease","volume":"377","author":"PM Ridker","year":"2017","journal-title":"New England Journal of Medicine"},{"issue":"1","key":"ref58","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/MOH.0000000000000389","article-title":"The regulation and importance of monocyte chemoattractant protein-1","volume":"25","author":"V Bianconi","year":"2018","journal-title":"Current opinion in hematology"},{"issue":"4","key":"ref59","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/QAD.0000000000000545","article-title":"The effect of HAART-induced HIV suppression on circulating markers of inflammation and immune activation","volume":"29","author":"NI Wada","year":"2015","journal-title":"AIDS (London, England)"},{"issue":"4","key":"ref60","doi-asserted-by":"crossref","first-page":"e0152588","DOI":"10.1371\/journal.pone.0152588","article-title":"D-Dimer Levels before HIV Seroconversion Remain Elevated Even after Viral Suppression and Are Associated with an Increased Risk of Non-AIDS Events","volume":"11","author":"MS Freiberg","year":"2016","journal-title":"PLoS One"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0214735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T16:34:47Z","timestamp":1721147687000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0214735"}},"subtitle":[],"editor":[{"given":"Cristian","family":"Apetrei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,4,4]]},"references-count":60,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0214735","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,4]]}}}