{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:04:25Z","timestamp":1778864665149,"version":"3.51.4"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T00:00:00Z","timestamp":1555545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0215530","type":"journal-article","created":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T17:42:42Z","timestamp":1555609362000},"page":"e0215530","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["Factors associated with uncontrolled asthma in adult asthmatics in Kinshasa, Democratic Republic of Congo"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4504-1258","authenticated-orcid":true,"given":"Benoit Obel","family":"Kabengele","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Marie Ntumba","family":"Kayembe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick Kalambayi","family":"Kayembe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zacharie Munogolo","family":"Kashongue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didine Kinkodi","family":"Kaba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre Zalagile","family":"Akilimali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,4,18]]},"reference":[{"key":"ref1","unstructured":"Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention, Update 2018. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.ginasthma.org\" xlink:type=\"simple\">www.ginasthma.org<\/ext-link>. Cited 23 May 2018."},{"key":"ref2","first-page":"5","article-title":"Asthma in Africa","author":"AA Awotedu","year":"2012"},{"key":"ref3","unstructured":"Global Asthma Network. The Global Asthma Report 2014. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.globalasthmareport.org\" xlink:type=\"simple\">http:\/\/www.globalasthmareport.org<\/ext-link>. Cited 23 May 2018."},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"e0176875","DOI":"10.1371\/journal.pone.0176875","article-title":"Prevalence and determinants of asthma in adults in Kinshasa","volume":"12","author":"KB Obel","year":"2017","journal-title":"PLoS One"},{"key":"ref5","first-page":"713","article-title":"Environnement et sant\u00e9 publique\u2014Fondements et pratiques","author":"P Lajoie","year":"2003"},{"key":"ref6","unstructured":"Afrite A, Allonier C, Com-Ruelle L and Le Guen N. L\u2019asthme en France en 2006: pr\u00e9valence, contr\u00f4le et d\u00e9terminants. Rapport Irdes 2011. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.irdes.fr\/Publications\/Rapports2011\/rap1820.pdf\" xlink:type=\"simple\">www.irdes.fr\/Publications\/Rapports2011\/rap1820.pdf<\/ext-link>. Cited 23 May 2018."},{"key":"ref7","unstructured":"Pin I. Que disent les recommandations internationales sur l\u2019adaptation du traitement de l\u2019asthme de l\u2019enfant en fonction de la s\u00e9v\u00e9rit\u00e9 et du contr\u00f4le en 2010. L\u2019asthme de l\u2019enfant de la clinique au traitement. Editions MED\u2019COM; 2012. pp 235\u2013244."},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/ACI.0b013e32835335ac","article-title":"Predictors of asthma control: what can we modify?","volume":"12","author":"M Schatz","year":"2012","journal-title":"Curr Opin Allergy Clin Immunol"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jaci.2003.09.008","article-title":"Development of the Asthma Control Test: A survey for assessing asthma control","volume":"113","author":"RA Nathan","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1183\/09059180.00001209","article-title":"Prevalence of asthma control among adults in France, Germany, Italy, Spain and The UK","volume":"18","author":"P Demoly","year":"2009","journal-title":"Eur Resp Rev"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/s12931-016-0374-z","article-title":"Determinants and impact of suboptimal asthma control in Europe: The International cross-sectional and longitudinal assessment on asthma control (LIAISON) study","volume":"17","author":"F Braido","year":"2016","journal-title":"Respir Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"14009","DOI":"10.1038\/npjpcrm.2014.9","article-title":"Asthma control and management in 8,000 European patients: the REcognise Asthma and LInk to Symptoms and Experience (REALISE) survey","volume":"24","author":"D Price","year":"2014","journal-title":"npj Prim Care Respir Med"},{"key":"ref13","first-page":"70","article-title":"Assessment of asthma control using asthma control test in chest clinics in Cameroon: a cross-sectional study","volume":"23","author":"MBH Ngahane","year":"2016","journal-title":"Pan Afr Med J"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"599","DOI":"10.15537\/smj.2015.5.10929","article-title":"Asthma control among adults in Saudi Arabia Study of determinants","volume":"36","author":"AA BinSaeed","year":"2015","journal-title":"Saudi Med J"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1710-1492-10-48","article-title":"Asthma in the elderly: a study of the role of vitamin D","volume":"10","author":"M Columbo","year":"2014","journal-title":"Allerg Asth Clinic Immunol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/2045-7022-3-3","article-title":"The skin prick test\u2014European standards","volume":"3","author":"L Heinzerling","year":"2013","journal-title":"Clin Transl Allergy"},{"key":"ref17","article-title":"Vademecum d\u2019explorations fonctionnelles respiratoires","author":"S Delpierre","year":"2013"},{"key":"ref18","unstructured":"Demeditec Diagnostics GmbH. 25-OH Vitamin D total RIA. Radioimmunoassay for the quantitative measurement of 25-hydroxy-vitamin D3 and D2 (25-OH-D2 and 25-OH-D3) in serum. User\u2019s Manuel."},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3109\/02770901003692777","article-title":"Determinants of asthma control in tertiary level in Turkey: a cross-sectional multicenter survey","volume":"47","author":"H Turktas","year":"2010","journal-title":"J Asthma"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1186\/s12890-016-0292-3","article-title":"Asthma control and severe exacerbations in patients with moderate or severe asthma in Jilin Province, China: a multicenter cross-sectional survey","volume":"16","author":"Yan Bd","year":"2016","journal-title":"BMC Pulm Med"},{"issue":"1","key":"ref21","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4314\/ejhs.v24i1.7","article-title":"Assessing control of asthma in Jush, Jimma, South West Ethiopia","volume":"24","author":"Z Kirubel","year":"2014","journal-title":"Ethiop J Health Sci"},{"issue":"2","key":"ref22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1177\/1479972314527468","article-title":"Does gender affect asthma control in adult asthmatics?","volume":"11","author":"AB Dursun","year":"2014","journal-title":"Chronic Respir Dis"},{"issue":"4","key":"ref23","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1590\/s1806-37562017000000216","article-title":"Asthma control, lung function, nutritional status, and health-related quality of life: differences between adult males and females with asthma","volume":"44","author":"GC Forte","year":"2018","journal-title":"J Bras Pneumol"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.rmed.2013.08.019","article-title":"Assessment of asthma control: The SERENA Study","volume":"107","author":"A Corrado","year":"2013","journal-title":"Respir Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"24109","DOI":"10.3402\/ecrj.v1.24109","article-title":"Determinants of uncontrolled asthma in a Swedish asthma population: cross-sectional observational study","volume":"1","author":"M K\u00e4mpe","year":"2014","journal-title":"Europ Clin Respir J"},{"issue":"6","key":"ref26","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.jaci.2007.03.022","article-title":"Real-world Evaluation of Asthma Control and Treatment (REACT): Findings from a national Web-based survey","volume":"119","author":"SP Peters","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.rmed.2018.03.024","article-title":"Asthma control in adults in the Middle East and North Africa: Results from the ESMAA study","volume":"138","author":"H Tarraf","year":"2018","journal-title":"Repir Med"},{"issue":"6","key":"ref28","first-page":"569","article-title":"Curr Opin Pulm Med","volume":"24","author":"J Kavanagh","year":"2018","journal-title":"Curr Opin Pulm Med"},{"key":"ref29","first-page":"426","article-title":"Total and specific IgE in Quebec children and adolescents and their relationship to respiratory symptoms","volume":"12","author":"B L\u00e9vesque","year":"2005","journal-title":"Can Resp J"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.rmr.2014.09.008","article-title":"Profil de sensibilisation aux pneumallerg\u00e8nes des patients suivis pour asthme \u00e0 Cotonou, B\u00e9nin: \u00e9tude transversale par prick-tests","volume":"32","author":"G Agodokpessi","year":"2015","journal-title":"Rev Mal Resp"},{"issue":"1","key":"ref31","first-page":"24","article-title":"Les ph\u00e9notypes cliniques de l\u2019asthme pendant l\u2019enfance","volume":"XXI","author":"J Just","year":"2018","journal-title":"La Lettre du Pneumologue"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1465-9921-14-25","article-title":"Severe and uncontrolled adult asthma is associated with vitamin D insufficiency and deficiency","volume":"14","author":"S Korn","year":"2013","journal-title":"Resp Res"},{"issue":"20","key":"ref33","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1001\/jama.2014.5052","article-title":"Effect of vitamin D on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial","volume":"31","author":"M Castro","year":"2014","journal-title":"JAMA"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"244","DOI":"10.3945\/an.111.000398","article-title":"Vitamin D and Chronic Lung Disease: A Review of Molecular mechanisms and Clinical Studies","volume":"2","author":"JD Finklea","year":"2011","journal-title":"Adv Nutr"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0215530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T07:52:48Z","timestamp":1589010768000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0215530"}},"subtitle":[],"editor":[{"given":"Heinz","family":"Fehrenbach","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,4,18]]},"references-count":34,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0215530","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,18]]}}}