{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T15:21:53Z","timestamp":1772205713924,"version":"3.50.1"},"reference-count":78,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Indonesian Danone Institute Foundation","award":["006\/I-CG\/IDIF\/XI\/2015"],"award-info":[{"award-number":["006\/I-CG\/IDIF\/XI\/2015"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0216848","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T13:41:41Z","timestamp":1596807701000},"page":"e0216848","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Maternal biomarker patterns for metabolism and inflammation in pregnancy are influenced by multiple micronutrient supplementation and associated with child biomarker patterns and nutritional status at 9-12 years of age"],"prefix":"10.1371","volume":"15","author":[{"given":"Lidwina","family":"Priliani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukma","family":"Oktavianthi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5388-081X","authenticated-orcid":true,"given":"Elizabeth L.","family":"Prado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7258-2586","authenticated-orcid":true,"given":"Safarina G.","family":"Malik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuraj H.","family":"Shankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2020,8,7]]},"reference":[{"key":"pone.0216848.ref001","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/BF00399095","article-title":"Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth","volume":"36","author":"DJP Barker","year":"1993","journal-title":"Diabetologia"},{"key":"pone.0216848.ref002","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/bmb\/60.1.5","article-title":"The thrifty phenotype hypothesisType 2 diabetes","volume":"60","author":"CN Hales","year":"2001","journal-title":"Br Med Bull"},{"key":"pone.0216848.ref003","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/nrendo.2009.195","article-title":"Nutritional programming of the metabolic syndrome","volume":"5","author":"ME Symonds","year":"2009","journal-title":"Nat Rev Endocrinol"},{"key":"pone.0216848.ref004","doi-asserted-by":"crossref","first-page":"e30616","DOI":"10.1371\/journal.pone.0030616","article-title":"Postnatal Growth after Intrauterine Growth Restriction Alters Central Leptin Signal and Energy Homeostasis","volume":"7","author":"B Coup\u00e9","year":"2012","journal-title":"PLOS ONE"},{"key":"pone.0216848.ref005","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.2527\/jas.2011-4343","article-title":"Maternal obesity upregulates fatty acid and glucose transporters and increases expression of enzymes mediating fatty acid biosynthesis in fetal adipose tissue depots","volume":"90","author":"NM Long","year":"2012","journal-title":"J Anim Sci"},{"key":"pone.0216848.ref006","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nrm2066","article-title":"Adipocyte differentiation from the inside out","volume":"7","author":"ED Rosen","year":"2006","journal-title":"Nat Rev Mol Cell Biol"},{"key":"pone.0216848.ref007","doi-asserted-by":"crossref","first-page":"1953S","DOI":"10.3945\/ajcn.110.001040","article-title":"The early programming of metabolic health: is epigenetic setting the missing link?","volume":"94","author":"S Sebert","year":"2011","journal-title":"Am J Clin Nutr"},{"key":"pone.0216848.ref008","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cca.2007.01.026","article-title":"Adiponectin as an anti-inflammatory factor","volume":"380","author":"N Ouchi","year":"2007","journal-title":"Clin Chim Acta Int J Clin Chem"},{"key":"pone.0216848.ref009","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.atherosclerosis.2006.04.012","article-title":"Plasma leptin: Associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease","volume":"191","author":"SG Wannamethee","year":"2007","journal-title":"Atherosclerosis"},{"key":"pone.0216848.ref010","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-2265.2011.03990.x","article-title":"High plasma retinol binding protein 4 (RBP4) is associated with systemic inflammation independently of low RBP4 adipose expression and is normalized by transplantation in nonobese, nondiabetic patients with chronic kidney disease","volume":"75","author":"R Barazzoni","year":"2011","journal-title":"Clin Endocrinol (Oxf)."},{"key":"pone.0216848.ref011","doi-asserted-by":"crossref","first-page":"e401595","DOI":"10.1155\/2014\/401595","article-title":"Adiponectin Levels Are Reduced While Markers of Systemic Inflammation and Aortic Remodelling Are Increased in Intrauterine Growth Restricted Mother-Child Couple","volume":"2014","author":"S Visentin","year":"2014","journal-title":"BioMed Res Int"},{"key":"pone.0216848.ref012","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.yfrne.2003.10.001","article-title":"Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance","volume":"24","author":"A. Sahu","year":"2003","journal-title":"Front Neuroendocrinol"},{"key":"pone.0216848.ref013","doi-asserted-by":"crossref","first-page":"349","DOI":"10.5604\/1232-1966.1108603","article-title":"The role of ghrelin, leptin and insulin in foetal development","volume":"21","author":"M Warcho\u0142","year":"2014","journal-title":"Ann Agric Environ Med AAEM"},{"key":"pone.0216848.ref014","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S1098-3597(08)60026-5","article-title":"Endocrine functions of adipose tissue: focus on adiponectin","volume":"9","author":"JR Sowers","year":"2008","journal-title":"Clin Cornerstone"},{"key":"pone.0216848.ref015","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/nature03711","article-title":"Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes","volume":"436","author":"Q Yang","year":"2005","journal-title":"Nature"},{"key":"pone.0216848.ref016","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/oby.2009.328","article-title":"Retinol-binding protein 4 (RBP4) protein expression is increased in omental adipose tissue of severely obese patients","volume":"18","author":"KR Kelly","year":"2010","journal-title":"Obes Silver Spring Md"},{"key":"pone.0216848.ref017","article-title":"Leptin and Leptin-to-Adiponectin Ratio Predict Adiposity Gain in Nonobese Children over a Six-Year Period","author":"M Zhang","year":"2017","journal-title":"Child Obes Print"},{"key":"pone.0216848.ref018","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/bbrc.1999.0255","article-title":"Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity","volume":"257","author":"Y Arita","year":"1999","journal-title":"Biochem Biophys Res Commun"},{"key":"pone.0216848.ref019","first-page":"873","article-title":"Increased visfatin and leptin in pregnancies complicated by pre-eclampsia","volume":"22","author":"E Adali","year":"2009","journal-title":"J Matern-Fetal Neonatal Med Off J Eur Assoc Perinat Med Fed Asia Ocean Perinat Soc Int Soc Perinat Obstet"},{"key":"pone.0216848.ref020","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1515\/jpm.2009.140","article-title":"Retinol Binding Protein 4 \u2013A Novel Association with Early-Onset Preeclampsia","volume":"38","author":"E Vaisbuch","year":"2010","journal-title":"J Perinat Med"},{"key":"pone.0216848.ref021","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1002\/oby.20128","article-title":"Maternal Serum Leptin During Pregnancy and Infant Birth Weight: the Influence of Maternal Overweight and Obesity","volume":"21","author":"VK Misra","year":"2013","journal-title":"Obes Silver Spring Md"},{"key":"pone.0216848.ref022","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s12291-013-0394-0","article-title":"Maternal Leptin, Adiponectin, Resistin, Visfatin and Tumor Necrosis Factor-Alpha in Normal and Gestational Diabetes","volume":"29","author":"AFH Noureldeen","year":"2014","journal-title":"Indian J Clin Biochem"},{"key":"pone.0216848.ref023","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/oby.20250","article-title":"Maternal and fetal leptin, adiponectin levels and associations with fetal insulin sensitivity","volume":"21","author":"Z-C Luo","year":"2013","journal-title":"Obes Silver Spring Md"},{"key":"pone.0216848.ref024","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJM200003233421202","article-title":"C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women","volume":"342","author":"PM Ridker","year":"2000","journal-title":"N Engl J Med"},{"key":"pone.0216848.ref025","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1093\/aje\/kwi323","article-title":"Plasma C-reactive protein in early pregnancy and preterm delivery","volume":"162","author":"W Pitiphat","year":"2005","journal-title":"Am J Epidemiol"},{"key":"pone.0216848.ref026","doi-asserted-by":"crossref","first-page":"132.e1","DOI":"10.1016\/j.ajog.2011.03.049","article-title":"C-reactive protein levels in early pregnancy, fetal growth patterns, and the risk for neonatal complications: the Generation R Study","volume":"205","author":"GDS Ernst","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"pone.0216848.ref027","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1002\/oby.21484","article-title":"Maternal inflammation during pregnancy and childhood adiposity","volume":"24","author":"R Gaillard","year":"2016","journal-title":"Obes Silver Spring Md"},{"key":"pone.0216848.ref028","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s00223-004-0227-5","article-title":"Plasma concentrations of 25-hydroxy-vitamin D and 1,25-dihydroxy-vitamin D are related to the phenotype of Gc (vitamin D-binding protein): a cross-sectional study on 595 early postmenopausal women","volume":"77","author":"AL Lauridsen","year":"2005","journal-title":"Calcif Tissue Int"},{"key":"pone.0216848.ref029","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S1043-2760(00)00317-9","article-title":"The multifunctional properties and characteristics of vitamin D-binding protein","volume":"11","author":"P White","year":"2000","journal-title":"Trends Endocrinol Metab TEM"},{"key":"pone.0216848.ref030","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/B978-0-12-386960-9.00010-1","article-title":"Maternal vitamin D during pregnancy and its relation to immune-mediated diseases in the offspring","volume":"86","author":"M Erkkola","year":"2011","journal-title":"Vitam Horm"},{"key":"pone.0216848.ref031","first-page":"113","article-title":"The Relationship between Maternal Vitamin D Deficiency and Low Birth Weight Neonates","volume":"9","author":"N Khalessi","year":"2015","journal-title":"J Fam Reprod Health"},{"key":"pone.0216848.ref032","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/1743-7075-9-59","article-title":"Zinc, vitamin A, and vitamin C status are associated with leptin concentrations and obesity in Mexican women: results from a cross-sectional study","volume":"9","author":"OP Garc\u00eda","year":"2012","journal-title":"Nutr Metab"},{"key":"pone.0216848.ref033","first-page":"241","article-title":"Plasma adiponectin concentrations are associated with dietary glycemic index in Malaysian patients with type 2 diabetes","volume":"22","author":"B-I Loh","year":"2013","journal-title":"Asia Pac J Clin Nutr"},{"key":"pone.0216848.ref034","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.clnu.2010.03.004","article-title":"Maternal diet and cord blood leptin and adiponectin concentrations at birth","volume":"29","author":"CS Mantzoros","year":"2010","journal-title":"Clin Nutr Edinb Scotl"},{"key":"pone.0216848.ref035","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.2337\/db08-0041","article-title":"Circulating Retinol-Binding Protein-4 Concentration Might Reflect Insulin Resistance\u2013Associated Iron Overload","volume":"57","author":"JM Fern\u00e1ndez-Real","year":"2008","journal-title":"Diabetes"},{"key":"pone.0216848.ref036","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.freeradbiomed.2008.09.030","article-title":"Vitamin C treatment reduces elevated C-reactive protein","volume":"46","author":"G Block","year":"2009","journal-title":"Free Radic Biol Med"},{"key":"pone.0216848.ref037","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1089\/ars.2015.6320","article-title":"Can l-Cysteine and Vitamin D Rescue Vitamin D and Vitamin D Binding Protein Levels in Blood Plasma of African American Type 2 Diabetic Patients?","volume":"23","author":"SK Jain","year":"2015","journal-title":"Antioxid Redox Signal"},{"key":"pone.0216848.ref038","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0140-6736(08)60133-6","article-title":"Effect of maternal multiple micronutrient supplementation on fetal loss and infant death in Indonesia: a double-blind cluster-randomised trial","volume":"371","author":"Supplementation with Multiple Micronutrients Intervention Trial (SUMMIT) Study Group","year":"2008","journal-title":"Lancet"},{"key":"pone.0216848.ref039","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/j.1365-3156.2012.03039.x","article-title":"Determinants of low birthweight, small-for-gestational-age and preterm birth in Lombok, Indonesia: analyses of the birthweight cohort of the SUMMIT trial","volume":"17","author":"SUMMIT Study Group","year":"2012","journal-title":"Trop Med Int Health TM IH"},{"key":"pone.0216848.ref040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0032519","article-title":"The Effect of Maternal Multiple Micronutrient Supplementation on Cognition and Mood during Pregnancy and Postpartum in Indonesia: A Randomized Trial.","volume":"7","author":"EL Prado","year":"2012","journal-title":"PLoS ONE"},{"key":"pone.0216848.ref041","doi-asserted-by":"crossref","first-page":"660","DOI":"10.2471\/BLT.07.043497","article-title":"Development of a WHO growth reference for school-aged children and adolescents","volume":"85","author":"M de Onis","year":"2007","journal-title":"Bull World Health Organ"},{"key":"pone.0216848.ref042","doi-asserted-by":"crossref","first-page":"e217","DOI":"10.1016\/S2214-109X(16)30354-0","article-title":"Maternal multiple micronutrient supplementation and other biomedical and socioenvironmental influences on children\u2019s cognition at age 9\u201312 years in Indonesia: follow-up of the SUMMIT randomised trial","volume":"5","author":"EL Prado","year":"2017","journal-title":"Lancet Glob Health"},{"key":"pone.0216848.ref043","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/BF02289447","article-title":"A RATIONALE AND TEST FOR THE NUMBER OF FACTORS IN FACTOR ANALYSIS","volume":"30","author":"JL Horn","year":"1965","journal-title":"Psychometrika"},{"key":"pone.0216848.ref044","volume-title":"Applied Multivariate Statistics for the Social Sciences, Fifth Edition","author":"JP Stevens","year":"2009","edition":"5"},{"key":"pone.0216848.ref045","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1038\/ejcn.2011.97","article-title":"Modifying effect of maternal nutritional status on the impact of maternal multiple micronutrient supplementation on birthweight in Indonesia","volume":"65","author":"SK Sebayang","year":"2011","journal-title":"Eur J Clin Nutr"},{"key":"pone.0216848.ref046","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.annepidem.2010.10.011","article-title":"Serum adiponectin in relation to body mass index and other correlates in black and white women","volume":"21","author":"SS Cohen","year":"2011","journal-title":"Ann Epidemiol"},{"key":"pone.0216848.ref047","doi-asserted-by":"crossref","first-page":"797","DOI":"10.3346\/jkms.2011.26.6.797","article-title":"Association of Serum Retinol Binding Protein 4 with Adiposity and Pubertal Development in Korean Children and Adolescents","volume":"26","author":"YJ Rhie","year":"2011","journal-title":"J Korean Med Sci"},{"key":"pone.0216848.ref048","doi-asserted-by":"crossref","DOI":"10.3390\/nu8060383","article-title":"Mother and Infant Body Mass Index, Breast Milk Leptin and Their Serum Leptin Values","volume":"8","author":"F Savino","year":"2016","journal-title":"Nutrients"},{"key":"pone.0216848.ref049","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1038\/ejcn.2014.296","article-title":"Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials","volume":"69","author":"S Saboori","year":"2015","journal-title":"Eur J Clin Nutr"},{"key":"pone.0216848.ref050","article-title":"The effect of vitamin D administration on serum leptin and adiponectin levels in end-stage renal disease patients on hemodialysis with vitamin D deficiency: A placebo-controlled double-blind clinical trial","volume":"21","author":"AE Naini","year":"2016","journal-title":"J Res Med Sci Off J Isfahan Univ Med Sci"},{"key":"pone.0216848.ref051","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1373\/clinchem.2006.071019","article-title":"Adiponectin and leptin in maternal serum, cord blood, and breast milk","volume":"52","author":"M Weyermann","year":"2006","journal-title":"Clin Chem"},{"key":"pone.0216848.ref052","doi-asserted-by":"crossref","DOI":"10.1111\/j.2047-6310.2012.00127.x","article-title":"Associations between perinatal factors and adiponectin and leptin in 9-year-old Mexican-American children","volume":"8","author":"V Volberg","year":"2013","journal-title":"Pediatr Obes"},{"key":"pone.0216848.ref053","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1203\/PDR.0b013e31823214ea","article-title":"Leptin in maternal serum and breast milk: association with infants\u2019 body weight gain in a longitudinal study over 6 months of lactation","volume":"70","author":"S Schuster","year":"2011","journal-title":"Pediatr Res"},{"key":"pone.0216848.ref054","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/sj.ijo.0801526","article-title":"Heritability of leptin levels and the shared genetic effects on body mass index and leptin in adult Finnish twins","volume":"25","author":"J Kaprio","year":"2001","journal-title":"Int J Obes Relat Metab Disord J Int Assoc Study Obes"},{"key":"pone.0216848.ref055","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1375\/twin.11.5.495","article-title":"Genetic and environmental influences on adiponectin, leptin, and BMI among adolescents in Taiwan: a multivariate twin\/sibling analysis","volume":"11","author":"P-H Liu","year":"2008","journal-title":"Twin Res Hum Genet Off J Int Soc Twin Stud"},{"key":"pone.0216848.ref056","doi-asserted-by":"crossref","first-page":"70","DOI":"10.2174\/157339508784325046","article-title":"Leptin and Inflammation","volume":"4","author":"N Iikuni","year":"2008","journal-title":"Curr Immunol Rev"},{"key":"pone.0216848.ref057","first-page":"1","article-title":"Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee","volume":"854","year":"1995","journal-title":"World Health Organ Tech Rep Ser"},{"key":"pone.0216848.ref058","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1210\/jc.2006-1390","article-title":"Influence of Serum Leptin on Weight and Body Fat Growth in Children at High Risk for Adult Obesity","volume":"92","author":"AF Fleisch","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"pone.0216848.ref059","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1159\/000308165","article-title":"Retinol-binding protein 4 levels in obese children and adolescents with glucose intolerance","volume":"73","author":"D Yeste","year":"2010","journal-title":"Horm Res Paediatr"},{"key":"pone.0216848.ref060","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1038\/oby.2007.155","article-title":"A community intervention reduces BMI z-score in children: Shape Up Somerville first year results","volume":"15","author":"CD Economos","year":"2007","journal-title":"Obes Silver Spring Md"},{"key":"pone.0216848.ref061","article-title":"Maternal Body Mass Index Is Strongly Associated with Children -Scores for Height and BMI","author":"PL Tigga","year":"2016","journal-title":"Journal of Anthropology"},{"key":"pone.0216848.ref062","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0142301","article-title":"Association between Maternal and Child Nutritional Status in Hula, Rural Southern Ethiopia: A Cross Sectional Study","volume":"10","author":"C Negash","year":"2015","journal-title":"PLoS ONE"},{"key":"pone.0216848.ref063","first-page":"39","article-title":"Diet Variety Based on Macronutrient Intake and Its Relationship With Body Mass Index","volume":"8","author":"TE Lyles","year":"2006","journal-title":"Medscape Gen Med"},{"key":"pone.0216848.ref064","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.biochi.2012.05.018","article-title":"Immunological functions of leptin and adiponectin","volume":"94","author":"F Carbone","year":"2012","journal-title":"Biochimie"},{"key":"pone.0216848.ref065","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.cmet.2017.02.006","article-title":"The Role of the Immune System in Metabolic Health and Disease","volume":"25","author":"N Zmora","year":"2017","journal-title":"Cell Metab"},{"key":"pone.0216848.ref066","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/01.AOG.0000114980.40445.83","article-title":"Transfer of inflammatory cytokines across the placenta","volume":"103","author":"MV Zaretsky","year":"2004","journal-title":"Obstet Gynecol"},{"key":"pone.0216848.ref067","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1007\/s10995-013-1220-2","article-title":"Maternal infection in pregnancy and risk of asthma in offspring","volume":"17","author":"CH Collier","year":"2013","journal-title":"Matern Child Health J"},{"key":"pone.0216848.ref068","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.bbadis.2013.07.007","article-title":"Maternal Nutrition and Risk of Obesity in Offspring: The Trojan Horse of Developmental Plasticity","volume":"1842","author":"SD Parlee","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"pone.0216848.ref069","unstructured":"WHO | Global prevalance of Vitamin A deficiency in populations at risk 1995\u20132005. In: WHO [Internet]. [cited 19 Aug 2019]. Available: https:\/\/www.who.int\/vmnis\/vitamina\/prevalence\/en\/"},{"key":"pone.0216848.ref070","first-page":"533","article-title":"Pregnancy-related mortality from preeclampsia and eclampsia","volume":"97","author":"AP MacKay","year":"2001","journal-title":"Obstet Gynecol"},{"key":"pone.0216848.ref071","doi-asserted-by":"crossref","first-page":"503.e1","DOI":"10.1016\/j.ajog.2011.02.020","article-title":"Supplementation with vitamins C and E during pregnancy for the prevention of preeclampsia and other adverse maternal and perinatal outcomes: a systematic review and metaanalysis","volume":"204","author":"A Conde-Agudelo","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"pone.0216848.ref072","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1093\/ajcn\/74.6.712","article-title":"Maternal thiamine deficiency: still a problem in some world communities","volume":"74","author":"RF Butterworth","year":"2001","journal-title":"Am J Clin Nutr"},{"issue":"Suppl 1","key":"pone.0216848.ref073","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-3016.2012.01277.x","article-title":"Interventions with vitamins B6, B12 and C in pregnancy","volume":"26","author":"DK Dror","year":"2012","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"Suppl 2","key":"pone.0216848.ref074","doi-asserted-by":"crossref","first-page":"S193","DOI":"10.1079\/BJN2000314","article-title":"Micronutrients in pregnancy","volume":"85","author":"RE Black","year":"2001","journal-title":"Br J Nutr"},{"key":"pone.0216848.ref075","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1749-6632.1993.tb26119.x","article-title":"Iodine supplementation and the prevention of cretinism","volume":"678","author":"JT Dunn","year":"1993","journal-title":"Ann N Y Acad Sci"},{"key":"pone.0216848.ref076","doi-asserted-by":"crossref","first-page":"499S","DOI":"10.1093\/ajcn\/68.2.499S","article-title":"Potential contribution of maternal zinc supplementation during pregnancy to maternal and child survival","volume":"68","author":"LE Caulfield","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"pone.0216848.ref077","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.placenta.2018.08.001","article-title":"Increased mitochondrial DNA copy number in maternal peripheral blood is associated with low birth weight in Lombok, Indonesia","volume":"70","author":"L Priliani","year":"2018","journal-title":"Placenta"},{"key":"pone.0216848.ref078","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1093\/jn\/nxz064","article-title":"Maternal Multiple Micronutrient Supplementation Stabilizes Mitochondrial DNA Copy Number in Pregnant Women in Lombok, Indonesia","volume":"149","author":"L Priliani","year":"2019","journal-title":"J Nutr"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0216848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T13:42:21Z","timestamp":1596807741000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0216848"}},"subtitle":[],"editor":[{"given":"Nancy","family":"Beam","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,7]]},"references-count":78,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0216848","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/625103","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,7]]}}}