{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T23:06:46Z","timestamp":1776121606557,"version":"3.50.1"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T00:00:00Z","timestamp":1561680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0218679","type":"journal-article","created":{"date-parts":[[2019,6,28]],"date-time":"2019-06-28T17:27:35Z","timestamp":1561742855000},"page":"e0218679","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Development of experimental pneumococcal vaccine for mucosal immunization"],"prefix":"10.1371","volume":"14","author":[{"given":"Tatiana","family":"Gupalova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9876-6594","authenticated-orcid":true,"given":"Galina","family":"Leontieva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Kramskaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kornelya","family":"Grabovskaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenia","family":"Kuleshevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Suvorov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,6,28]]},"reference":[{"issue":"1","key":"ref1","first-page":"7","article-title":"Development of pneumococcal vaccines over the last 10 years","volume":"18","author":"N Principi","year":"2018","journal-title":"Expert OpinBiolTher"},{"issue":"1","key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11908-018-0607-z","article-title":"Prevention of Invasive Pneumococcal Disease: Problems Emerged After Some Years of the 13-Valent Pneumococcal Conjugate Vaccine Use","volume":"20","author":"N Principi","year":"2018","journal-title":"Curr Infect Dis Rep"},{"issue":"6016","key":"ref3","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1126\/science.1198545","article-title":"Rapid pneumococcal evolution in response to clinical interventions","volume":"331","author":"NJ Croucher","year":"2011","journal-title":"Science"},{"issue":"6","key":"ref4","article-title":"Chimeric Protein PSPF, a Potential Vaccine for Prevention <italic>Streptococcus pneumonia<\/italic> Infection \/\/ Vaccines &amp; Vaccination","volume":"6","author":"A Suvorov","year":"2015","journal-title":"Chimeric Protein PSPF, a Potential Vaccine for Prevention"},{"issue":"11","key":"ref5","doi-asserted-by":"crossref","first-page":"e0206661","DOI":"10.1371\/journal.pone.0206661","article-title":"Nasal immunization with recombinant chimeric pneumococcal protein and cell wall from immunobiotic bacteria improve resistance of infant mice to Streptococcus pneumoniae infection","volume":"13","author":"J Lai\u00f1o","year":"2018","journal-title":"PLoS One"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"e0196564","DOI":"10.1371\/journal.pone.0196564","article-title":"Development of experimental GBS vaccine for mucosal immunization","volume":"13","author":"T Gupalova","year":"2018","journal-title":"PLoS One"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.synbio.2016.12.002","article-title":"Novel polysaccharide-protein conjugates provide an immunogenic 13-valent pneumococcal conjugate vaccine for S. pneumonia","volume":"2","author":"Allison E.B. Turner","year":"2017","journal-title":"Synthetic and Systems Biotechnology"},{"issue":"Suppl 1","key":"ref8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/1469-0691.12320","article-title":"Experience with pneumococcal polysaccharide conjugate vaccine (conjugated to CRM197 carrier protein) in children and adults","volume":"19","author":"P Durando","year":"2013","journal-title":"ClinMicrobiol Infect"},{"issue":"10","key":"ref9","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1586\/14760584.2016.1167602","article-title":"Maternal and neonatal pneumococcal vaccination\u2014where are we now?","volume":"15","author":"E Clarke","year":"2016","journal-title":"Expert Rev Vaccines"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1208\/s12248-009-9168-2","article-title":"Intranasal Delivery of Influenza Subunit Vaccine Formulated with GEM Particles as an AdjuvantVinaySaluja","volume":"12","author":"Jean P. Amorij","year":"2010","journal-title":"AAPS J"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1089\/vim.2007.0027","article-title":"A novel intranasal virus-like particle (VLP) vaccine designed to protect against the pandemic 1918 influenza A virus (H1N1)","volume":"20","author":"D Matassov","year":"2007","journal-title":"Viral Immunol"},{"issue":"18","key":"ref12","doi-asserted-by":"crossref","first-page":"3990","DOI":"10.1016\/j.vaccine.2005.12.017","article-title":"A new intranasal influenza vaccine based on a novel polycationic lipid\u2014ceramide carbamoyl-spermine (CCS). I. Immunogenicity and efficacy studies in mice","volume":"24","author":"A Joseph","year":"2006","journal-title":"Vaccine"},{"issue":"20\u201322","key":"ref13","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1016\/S0264-410X(00)00556-9","article-title":"Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity","volume":"19","author":"L Haan","year":"2001","journal-title":"Vaccine"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.ymeth.2005.09.015","article-title":"Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria","volume":"38","author":"ML Van Roosmalen","year":"2006","journal-title":"Methods"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3390\/microorganisms5020017","article-title":"Probiotic Microorganisms: A Closer Look","volume":"5","author":"J Villena","year":"2017","journal-title":"Microorganisms"},{"issue":"4","key":"ref16","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1208\/s12248-015-9719-7","article-title":"Intranasal Delivery of Proteins and Peptides in the Treatment of Neurodegenerative Diseases","volume":"17","author":"M. Elizabeth Meredith","journal-title":"The AAPS Journal"},{"key":"ref17","first-page":"71","article-title":"The Human Microbiota in Health and Disease Engineering","volume":"3","author":"Baohong Wang","year":"2017","journal-title":"The Human Microbiota in Health and Disease Engineering"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.3389\/fmicb.2018.01869","article-title":"Autoprobiotics as an Approach for Restoration of Personalised Microbiota","volume":"9","author":"A Suvorov","year":"2018","journal-title":"Front Microbiol"},{"issue":"41","key":"ref19","doi-asserted-by":"crossref","first-page":"15163","DOI":"10.3748\/wjg.v20.i41.15163","article-title":"Intestinal microbiota in health and disease: role of bifidobacteria in gut homeostasis","volume":"20","author":"R Tojo","year":"2014","journal-title":"World J Gastroenterol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/B978-0-12-415847-4.00050-1","article-title":"Discriminating Pathogens from Commensals at Mucosal","volume":"1","author":"Laetitia Aymeric","year":"2015","journal-title":"Mucosal Immunology"},{"key":"ref21","first-page":"1","article-title":"Influence of monostrain and multistrain probiotics on immunity, intestinal ultrastructure and microbiota in experimental dysbiosis","volume":"13","author":"E Ermolenko","year":"2018","journal-title":"Benef Microbes"},{"issue":"35","key":"ref22","doi-asserted-by":"crossref","first-page":"4376","DOI":"10.1016\/j.vaccine.2013.12.026","article-title":"The delicate balance in genetically engineering live vaccines","volume":"32","author":"James E. Galen","year":"2014","journal-title":"Vaccine"},{"issue":"2\u20133","key":"ref23","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0928-8244(03)00063-4","article-title":"Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunization","volume":"37","author":"HY Kang","year":"2003","journal-title":"FEMS Immunol Med Microbiol"},{"issue":"3","key":"ref24","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1086\/596066","article-title":"Mucosal immunization with attenuated Salmonella entericaserovarTyphi expressing protective antigen of anthrax toxin (PA83) primes monkeys for accelerated serum antibody responses to parenteral PA83 vaccine","volume":"199","author":"JE Galen","journal-title":"J Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13104-016-2353-3","article-title":"Invasive pneumococcal disease caused by mucoid serotype 3 reptococcuspneumoniae: a case report and literature review","volume":"10","author":"Naomi Sugimoto","year":"2017","journal-title":"BMC Research Notes"},{"issue":"9","key":"ref26","first-page":"2198","article-title":"Immunogenicity and safety of the 13-valent pneumococcal conjugate vaccine compared to the 23-valent pneumococcal polysaccharide vaccine in elderly Japanese adults","volume":"11","author":"M Shiramoto","year":"2015","journal-title":"Hum VaccinImmunother"},{"issue":"9","key":"ref27","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S1473-3099(14)70822-9","article-title":"Serotype-specific effectiveness and correlates of protection for the 13-valent pneumococcal conjugate vaccine: a postlicensure indirect cohort study","volume":"14","author":"NJ Andrews","year":"2014","journal-title":"Lancet Infect Dis"},{"issue":"9","key":"ref28","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.1128\/IAI.00408-13","article-title":"Increased Susceptibility of IgA-Deficient Mice to Pulmonary Francisellatularensis","volume":"81","author":"Yoichi Furuya","year":"2013","journal-title":"Infect Immun"},{"key":"ref29","first-page":"13","article-title":"Overview of the mucosal immune system \/","volume":"146","author":"P. Brandtzaeg","year":"1989","journal-title":"Curr. Top. Microbiol. Immunol"},{"issue":"18","key":"ref30","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1093\/intimm\/dxl017","article-title":"Polymeric IgR knockout mice are more susceptible to mycobacterial infections in the respiratory tract than wild-type mice","author":"A Tjarnlund","year":"2006","journal-title":"Int. Immunol"},{"issue":"63","key":"ref31","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1365-3083.2006.01725.x","article-title":"Immunoglobulin A and CD8 T-cell mucosal immune defenses protect against intranasal infection with Chlamydia pneumoniae","author":"A Rodriguez","year":"2006","journal-title":"Scand. J. Immunol"},{"issue":"75","key":"ref32","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1128\/IAI.01606-06","article-title":"Inactivated <italic>Francisellatularensis<\/italic> live vaccine strain protects against respiratory tularemia by intranasal vaccination in an immunoglobulin A-dependent fashion","author":"SD Baron","year":"2007","journal-title":"Infect. Immun"},{"issue":"230","key":"ref33","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.cellimm.2004.09.002","article-title":"Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice","author":"AK Murthy","year":"2004","journal-title":"Cell. Immunol"},{"issue":"3","key":"ref34","doi-asserted-by":"crossref","first-page":"e89831","DOI":"10.1371\/journal.pone.0089831","article-title":"Genetic Factors Regulating Lung Vasculature and Immune Cell Functions Associate with Resistance to Pneumococcal Infection","volume":"9","author":"Magda S. Jonczyk","year":"2014","journal-title":"PLoS One"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0218679","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T10:17:16Z","timestamp":1663841836000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0218679"}},"subtitle":[],"editor":[{"given":"Daniela Flavia","family":"Hozbor","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,6,28]]},"references-count":34,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,6,28]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0218679","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,28]]}}}