{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:38:04Z","timestamp":1778798284012,"version":"3.51.4"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0220200","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T17:27:56Z","timestamp":1564162076000},"page":"e0220200","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["Evaluation of alternately combining HPV viral load and 16\/18 genotyping in secondary screening algorithms"],"prefix":"10.1371","volume":"14","author":[{"given":"Hongxue","family":"Luo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome L.","family":"Belinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4231-0774","authenticated-orcid":true,"given":"Ruifang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,7,26]]},"reference":[{"key":"ref1","first-page":"1","article-title":"Human papillomaviruses and their possible role in squamous cell carcinomas","volume":"78","author":"HH Zur","year":"1977","journal-title":"Curr Top MicrobiolImmunol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F","article-title":"Human papillomavirus is a necessary cause of invasive cervical cancer worldwide","volume":"189","author":"JM Walboomers","year":"1999","journal-title":"J Pathol"},{"issue":"9916","key":"ref3","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0140-6736(13)62218-7","article-title":"Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials","volume":"383","author":"G Ronco","year":"2014","journal-title":"Lancet"},{"issue":"Suppl 5","key":"ref4","doi-asserted-by":"crossref","first-page":"F88","DOI":"10.1016\/j.vaccine.2012.06.095","article-title":"Evidence Regarding Human Papillomavirus Testing in Secondary Prevention of Cervical Cancer","volume":"30","author":"M Arbyn","year":"2012","journal-title":"Vaccine"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1002\/ijc.27650","article-title":"EUROGIN 2011 roadmap on prevention and treatment of HPV-related disease","volume":"131","author":"M Arbyn","year":"2012","journal-title":"Int J Cancer"},{"issue":"5","key":"ref6","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1093\/annonc\/mdt538","article-title":"Cervical cancer screening: on the way to a shift from cytology to full molecular screening","volume":"25","author":"MG Dijkstra","year":"2014","journal-title":"Ann Oncol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1586\/14737140.2014.856273","article-title":"The current position and the future perspectives of cervical cancer screening","volume":"14","author":"RP Bosgraaf","year":"2014","journal-title":"Expert Rev Anticancer Ther"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S1473-3099(07)70158-5","article-title":"Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis","volume":"7","author":"S de Sanjose","year":"2007","journal-title":"Lancet Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S1470-2045(12)70568-5","article-title":"Triage of HPV-positive women in cervical cancer screening","volume":"14","author":"N. Wentzensen","year":"2013","journal-title":"Lancet Oncol"},{"key":"ref10","first-page":"51","article-title":"Triaging HPV-positive women with p16\/Ki-67 dual-stained cytology: Results from a sub-study nested into the ATHENA trial","volume":"144","author":"TC Wright Jr","year":"2017","journal-title":"GynecolOncol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/ijc.26056","article-title":"Evaluation of 14 triage strategies for HPV DNA-positive women in population-based cervical screening","volume":"130","author":"DC Rijkaart","year":"2012","journal-title":"Int J Cancer"},{"key":"ref12","first-page":"330","article-title":"Use of primary high-risk human papillomavirus testing for cervical cancer screening: Interim clinical guidance","volume":"125","author":"WK Huh","year":"2015","journal-title":"ObstetGynecol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"184.e1","DOI":"10.1016\/j.ajog.2012.11.020","article-title":"Comparison of cervical cancer screening strategies incorporating different combinations of cytology, HPV testing, and genotyping for HPV 16\/18: Results from the ATHENA HPV study","volume":"208","author":"JT Cox","year":"2013","journal-title":"Am J ObstetGynecol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/S1470-2045(11)70188-7","article-title":"Performance of carcinogenic human papillomavirus (HPV) testing and HPV16 or HPV18 genotyping for cervical cancer screening of women aged 25 years and older: a subanalysis of the ATHENA study","volume":"12","author":"PE Castle","year":"2011","journal-title":"Lancet Oncol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/LGT.0000000000000277","article-title":"Evaluation of Viral Load as a Triage Strategy With Primary High-Risk Human Papillomavirus Cervical Cancer Screening","volume":"21","author":"H Luo","year":"2017","journal-title":"J Low Genit Tract Dis"},{"key":"ref16","first-page":"790","article-title":"A Population-Based Clinical Trial Comparing Endocervical High-Risk HPV Testing Using Hybrid Capture 2 and CervistaFrom the SHENCCAST II Study","volume":"135","author":"JL Belinson","year":"2011","journal-title":"Am J ClinPathol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1002\/ijc.26202","article-title":"Improved sensitivity of vaginal self-collection and high-risk human papillomavirus testing","volume":"130","author":"JL Belinson","year":"2012","journal-title":"Int J Cancer"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1097\/LGT.0b013e31824f48c8","article-title":"Secondary screening after primary self-sampling for human papillomavirus from SHENCCAST II","volume":"16","author":"R Wu","year":"2012","journal-title":"J Low Genit Tract Dis"},{"issue":"11","key":"ref19","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1158\/1055-9965.EPI-05-0240","article-title":"Association between quantitative high-risk human papillomavirus DNA load and cervical intraepithelial neoplasm risk","volume":"14","author":"HT Tsai","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref20","first-page":"264","article-title":"Associations of high-risk HPV types and viral load with cervical cancer in China","volume":"35","author":"Y Wu","year":"2006","journal-title":"J ClinVirol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1097\/IGC.0b013e318286a95d","article-title":"Six-year regression and progression of cervical lesions of different human papillomavirus viral loads in varied histological diagnoses","volume":"23","author":"SM Wang","year":"2013","journal-title":"Int J Gynecol Cancer"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e107573","DOI":"10.1371\/journal.pone.0107573","article-title":"Meta-Analysis on Prevalence and Attribution of Human Papillomavirus Types 52 and 58 in Cervical Neoplasia Worldwide","volume":"9","author":"PK Chan","year":"2014","journal-title":"PLoS One"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1093\/jjco\/hyu112","article-title":"Human papillomavirus genotype distribution in cervical intraepithelial neoplasia grade 2\/3 and invasive cervical cancer in Japanese women","volume":"44","author":"Y Azuma","year":"2014","journal-title":"Jpn J ClinOncol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/LGT.0000000000000243","article-title":"Analysis of Human Papillomavirus Infection in 16,320 Patients From a Gynecology Clinic in Central South China","volume":"20","author":"SS Xiao","year":"2016","journal-title":"J Low Genit Tract Dis"},{"issue":"3","key":"ref25","first-page":"505","article-title":"Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16\/Ki-67 Dual-stained cytology","volume":"121","author":"KU Petry","year":"2011","journal-title":"GynecolOncol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1002\/ijc.28723","article-title":"Methylation marker analysis of self-sampled cervico-vaginal lavage specimens to triage high-risk HPV-positive women for colposcopy","volume":"135","author":"AT Hesselink","year":"2014","journal-title":"Int J Cancer"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0220200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T13:16:04Z","timestamp":1589030164000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0220200"}},"subtitle":[],"editor":[{"given":"Kalimuthusamy","family":"Natarajaseenivasan","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,7,26]]},"references-count":26,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,7,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0220200","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,26]]}}}