{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:19:07Z","timestamp":1793395147116,"version":"4.5.0"},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T00:00:00Z","timestamp":1566518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Samsung Medical Center","award":["the 20 by 20 Project (Best #3, GFO1150091)"],"award-info":[{"award-number":["the 20 by 20 Project (Best #3, GFO1150091)"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0221042","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T13:35:07Z","timestamp":1566567307000},"page":"e0221042","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":29,"title":["Increased risk of refeeding syndrome\u2013like hypophosphatemia with high initial amino acid intake in small-for-gestational-age, extremely-low-birthweight infants"],"prefix":"10.1371","volume":"14","author":[{"given":"Se In","family":"Sung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun Sil","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Hwa","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohan","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisook","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So Yoon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8245-4692","authenticated-orcid":true,"given":"Won Soon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,8,23]]},"reference":[{"key":"pone.0221042.ref001","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1203\/PDR.0b013e318217f4f1","article-title":"Early nutrition mediates the influence of severity of illness on extremely LBW infants","volume":"69","author":"RA Ehrenkranz","year":"2011","journal-title":"Pediatr Res"},{"key":"pone.0221042.ref002","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/sj.jp.7211611","article-title":"Safety and efficacy of early amino acids in preterm <28 weeks gestation: prospective observational comparison","volume":"26","author":"K Kotsopoulos","year":"2006","journal-title":"J Perinatol"},{"key":"pone.0221042.ref003","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1016\/j.clnu.2018.06.945","article-title":"ESPGHAN\/ESPEN\/ESPR\/CSPEN guidelines on pediatric parenteral nutrition: Amino acids","volume":"37","author":"nutrition EEECwgopp","year":"2018","journal-title":"Clin Nutr"},{"key":"pone.0221042.ref004","first-page":"CD005949","article-title":"Higher versus lower amino acid intake in parenteral nutrition for newborn infants","volume":"3","author":"DA Osborn","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"issue":"Suppl 2","key":"pone.0221042.ref005","first-page":"S1","article-title":"1. Guidelines on Paediatric Parenteral Nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), Supported by the European Society of Paediatric Research (ESPR)","volume":"41","author":"Parenteral Nutrition Guidelines Working G","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"pone.0221042.ref006","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1203\/00006450-200301000-00008","article-title":"Effect of low versus high intravenous amino acid intake on very low birth weight infants in the early neonatal period","volume":"53","author":"PJ Thureen","year":"2003","journal-title":"Pediatr Res"},{"key":"pone.0221042.ref007","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0022-3476(95)70083-8","article-title":"Immediate commencement of amino acid supplementation in preterm infants: effect on serum amino acid concentrations and protein kinetics on the first day of life","volume":"127","author":"JB Van Goudoever","year":"1995","journal-title":"J Pediatr"},{"key":"pone.0221042.ref008","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/ejcn.2011.79","article-title":"The effect of parenteral nitrogen and energy intake on electrolyte balance in the preterm infant","volume":"65","author":"F Bonsante","year":"2011","journal-title":"Eur J Clin Nutr"},{"key":"pone.0221042.ref009","doi-asserted-by":"crossref","first-page":"e72880","DOI":"10.1371\/journal.pone.0072880","article-title":"Initial amino acid intake influences phosphorus and calcium homeostasis in preterm infants\u2014it is time to change the composition of the early parenteral nutrition","volume":"8","author":"F Bonsante","year":"2013","journal-title":"PLoS One"},{"key":"pone.0221042.ref010","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1515\/jpem-2011-0485","article-title":"Hypophosphatemia in small for gestational age extremely low birth weight infants receiving parenteral nutrition in the first week after birth","volume":"25","author":"G Ichikawa","year":"2012","journal-title":"J Pediatr Endocrinol Metab"},{"key":"pone.0221042.ref011","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1111\/j.1442-200X.2012.03590.x","article-title":"Refeeding syndrome in a small-for-dates micro-preemie receiving early parenteral nutrition","volume":"54","author":"H Mizumoto","year":"2012","journal-title":"Pediatr Int"},{"key":"pone.0221042.ref012","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.clnu.2012.09.004","article-title":"Enhanced feeding in very-low-birth-weight infants may cause electrolyte disturbances and septicemia\u2014a randomized, controlled trial","volume":"32","author":"SJ Moltu","year":"2013","journal-title":"Clin Nutr"},{"key":"pone.0221042.ref013","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.pcl.2009.06.006","article-title":"Refeeding syndrome","volume":"56","author":"J Fuentebella","year":"2009","journal-title":"Pediatr Clin North Am"},{"key":"pone.0221042.ref014","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1177\/014860719001400190","article-title":"The refeeding syndrome: a review","volume":"14","author":"SM Solomon","year":"1990","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"pone.0221042.ref015","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1111\/apa.13093","article-title":"Extremely preterm infants who are small for gestational age have a high risk of early hypophosphatemia and hypokalemia","volume":"104","author":"F Boubred","year":"2015","journal-title":"Acta Paediatr"},{"key":"pone.0221042.ref016","doi-asserted-by":"crossref","first-page":"9748031","DOI":"10.1155\/2017\/9748031","article-title":"Risk Factors for the Development of Refeeding Syndrome-Like Hypophosphatemia in Very Low Birth Weight Infants","volume":"2017","author":"A Igarashi","year":"2017","journal-title":"Dis Markers"},{"key":"pone.0221042.ref017","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1159\/000260135","article-title":"Fatal effects of a neonatal high-protein diet in low-birth-weight piglets used as a model of intrauterine growth restriction","volume":"97","author":"A Jamin","year":"2010","journal-title":"Neonatology"},{"key":"pone.0221042.ref018","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/jp.2013.28","article-title":"Refeeding syndrome in very-low-birth-weight intrauterine growth-restricted neonates","volume":"33","author":"JR Ross","year":"2013","journal-title":"J Perinatol"},{"key":"pone.0221042.ref019","doi-asserted-by":"crossref","first-page":"e214","DOI":"10.1542\/peds.2009-0913","article-title":"New intrauterine growth curves based on United States data","volume":"125","author":"IE Olsen","year":"2010","journal-title":"Pediatrics"},{"key":"pone.0221042.ref020","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1159\/000276979","article-title":"Standardized parenteral nutrition in preterm infants: early impact on fluid and electrolyte balance","volume":"98","author":"S Iacobelli","year":"2010","journal-title":"Neonatology"},{"key":"pone.0221042.ref021","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jpeds.2005.10.038","article-title":"Early provision of parenteral amino acids in extremely low birth weight infants: relation to growth and neurodevelopmental outcome","volume":"148","author":"National Institute of Child H, Human Development Neonatal Research N","year":"2006","journal-title":"J Pediatr"},{"key":"pone.0221042.ref022","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/jpen.1426","article-title":"Early Hypophosphatemia in High-Risk Preterm Infants: Efficacy and Safety of Sodium Glycerophosphate From First Day on Parenteral Nutrition","volume":"43","author":"G Bustos Lozano","year":"2019","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"pone.0221042.ref023","doi-asserted-by":"crossref","first-page":"F451","DOI":"10.1136\/archdischild-2016-311107","article-title":"Severe hypercalcaemia and hypophosphataemia with an optimised preterm parenteral nutrition formulation in two epochs of differing phosphate supplementation","volume":"102","author":"S Mulla","year":"2017","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"pone.0221042.ref024","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/jp.2013.181","article-title":"Transient hyperinsulinemia may be responsible from electrolyte abnormalities of refeeding syndrome seen in very low birth weight infants with intrauterine growth-restriction","volume":"34","author":"N Hakan","year":"2014","journal-title":"J Perinatol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0221042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T20:25:51Z","timestamp":1588969551000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0221042"}},"subtitle":[],"editor":[{"given":"Olivier","family":"Baud","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,8,23]]},"references-count":24,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2019,8,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0221042","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,23]]}}}