{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:09:17Z","timestamp":1790694557236,"version":"4.1.0"},"reference-count":72,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T00:00:00Z","timestamp":1566259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"KAKENHI grant","award":["16K08478"],"award-info":[{"award-number":["16K08478"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0221440","type":"journal-article","created":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T17:48:11Z","timestamp":1566409691000},"page":"e0221440","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB\/cAJ mice"],"prefix":"10.1371","volume":"14","author":[{"given":"Md. Mosharaf","family":"Hossain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takamasa","family":"Tsuzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Sakakibara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumitaka","family":"Imaizumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Ikegaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mami","family":"Inagaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuko","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuji","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyota","family":"Takamatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Kumanogoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Negishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9082-0170","authenticated-orcid":true,"given":"Kazunori","family":"Yukawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,8,20]]},"reference":[{"issue":"1","key":"pone.0221440.ref001","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.conb.2007.01.008","article-title":"Commissure formation in the mammalian forebrain","volume":"17","author":"C Lindwall","year":"2007","journal-title":"Curr Opin Neurobiol"},{"issue":"2","key":"pone.0221440.ref002","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/cne.901640206","article-title":"Interhemispheric neocortical connections of the corpus callosum in the normal mouse: a study based on anterograde and retrograde methods","volume":"164","author":"CH Yorke","year":"1975","journal-title":"J Comp Neurol"},{"issue":"1\u20132","key":"pone.0221440.ref003","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0006-8993(92)90178-C","article-title":"Fiber composition of the human corpus callosum","volume":"598","author":"F Aboitiz","year":"1992","journal-title":"Brain Res"},{"issue":"1","key":"pone.0221440.ref004","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.bbr.2011.04.018","article-title":"How does the corpus callosum mediate interhemispheric transfer? A review","volume":"223","author":"LJ van der Knaap","year":"2011","journal-title":"Behav Brain Res"},{"issue":"3","key":"pone.0221440.ref005","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0387-7604(87)80042-6","article-title":"Clinicopathological findings associated with agenesis of the corpus callosum","volume":"9","author":"JS Jeret","year":"1987","journal-title":"Brain Dev"},{"issue":"5","key":"pone.0221440.ref006","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1111\/j.1365-2214.2009.00942.x","article-title":"Physical, motor, sensory and developmental features associated with agenesis of the corpus callosum","volume":"35","author":"P Moes","year":"2009","journal-title":"Child Care Health Dev"},{"issue":"8","key":"pone.0221440.ref007","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1001\/archneur.1995.00540320070014","article-title":"Reduced size of corpus callosum in autism","volume":"52","author":"B Egaas","year":"1995","journal-title":"Arch Neurol"},{"issue":"19","key":"pone.0221440.ref008","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0006-3223(96)00349-6","article-title":"The corpus callosum and lateral ventricles in children with attention-deficit hyperactivity disorder: a brain magnetic resonance imaging study","volume":"40","author":"IK Lyoo","year":"1996","journal-title":"Biol Psychiatry"},{"key":"pone.0221440.ref009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyt.2012.00001","article-title":"Agenesis of corpus callosum and emotional information processing in schizophrenia","volume":"3","author":"O Lungu","year":"2012","journal-title":"Front Psychiatry"},{"issue":"11\u201312","key":"pone.0221440.ref010","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00335-010-9292-4","article-title":"A novel locus on proximal chromosome 18 associated with agenesis of the corpus callosum in mice","volume":"21","author":"S Mizuno","year":"2010","journal-title":"Mamm Genome"},{"key":"pone.0221440.ref011","doi-asserted-by":"crossref","first-page":"149060","DOI":"10.1155\/2013\/149060","article-title":"Axon guidance mechanisms for establishment of callosal connections","volume":"2013","author":"M Nishikimi","year":"2013","journal-title":"Neural Plast"},{"issue":"5","key":"pone.0221440.ref012","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.tins.2015.02.007","article-title":"Contralateral targeting of the corpus callosum in normal and pathological brain function","volume":"38","author":"LR Fenlon","year":"2015","journal-title":"Trends Neurosci"},{"issue":"5","key":"pone.0221440.ref013","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S1474-4422(14)70257-1","article-title":"Axon guidance proteins in neurological disorders","volume":"14","author":"EY Van Battum","year":"2015","journal-title":"Lancet Neurol"},{"issue":"5","key":"pone.0221440.ref014","first-page":"267","article-title":"Agenesis of the corpus callosum: lessons from humans and mice","volume":"28","author":"D Kamnasaran","year":"2005","journal-title":"Clin Invest Med"},{"key":"pone.0221440.ref015","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0070-2153(05)69010-2","article-title":"Mechanisms of axon guidance in the developing nervous system","volume":"69","author":"C Plachez","year":"2005","journal-title":"Curr Top Dev Biol"},{"issue":"21","key":"pone.0221440.ref016","doi-asserted-by":"crossref","first-page":"3746","DOI":"10.1242\/dev.119909","article-title":"EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex","volume":"142","author":"JW Lim","year":"2015","journal-title":"Development"},{"issue":"1","key":"pone.0221440.ref017","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/cne.903230107","article-title":"Prenatal formation of the normal mouse corpus callosum: a quantitative study with carbocyanine dyes","volume":"323","author":"HS Ozaki","year":"1992","journal-title":"J. Comp. Neurol"},{"issue":"12","key":"pone.0221440.ref018","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1590\/S0100-879X2002001200004","article-title":"Axonal pathfinding mechanisms at the cortical midline and in the development of the corpus callosum","volume":"35","author":"LJ Richards","year":"2002","journal-title":"Braz. J. Med. Biol. Res"},{"key":"pone.0221440.ref019","doi-asserted-by":"crossref","first-page":"i11","DOI":"10.1093\/cercor\/bhp027","article-title":"Neuropilin 1-Sema Signaling Regulates Crossing of Cingulate Pioneering Axons during Development of the Corpus Callosum","volume":"1","author":"M Piper","year":"2009","journal-title":"Cerebral Cortex"},{"issue":"5290","key":"pone.0221440.ref020","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1126\/science.274.5290.1123","article-title":"The molecular biology of axon guidance","volume":"274","author":"M Tessier Lavigne","year":"1996","journal-title":"Science"},{"issue":"5600","key":"pone.0221440.ref021","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1126\/science.1072165","article-title":"Molecular Mechanisms of Axon Guidance","volume":"298","author":"BJ Dickson","year":"2002","journal-title":"Science"},{"issue":"6","key":"pone.0221440.ref022","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0092-8674(00)81795-X","article-title":"Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system","volume":"87","author":"T Serafini","year":"1996","journal-title":"Cell"},{"issue":"8","key":"pone.0221440.ref023","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1523\/JNEUROSCI.21-08-02749.2001","article-title":"Cortical axon guidance by the glial wedge during the development of the corpus callosum","volume":"21","author":"T Shu","year":"2001","journal-title":"J Neurosci"},{"issue":"2","key":"pone.0221440.ref024","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0896-6273(02)00561-5","article-title":"Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain","volume":"33","author":"A Bagri","year":"2002","journal-title":"Neuron"},{"issue":"10","key":"pone.0221440.ref025","doi-asserted-by":"crossref","first-page":"e1000230","DOI":"10.1371\/journal.pbio.1000230","article-title":"Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C","volume":"7","author":"M Niquille","year":"2009","journal-title":"PLoS Biol"},{"issue":"340","key":"pone.0221440.ref026","doi-asserted-by":"crossref","first-page":"ra81","DOI":"10.1126\/scisignal.2005334","article-title":"Semaphorin 3A activates the guanosine triphosphatase Rab5 to promote growth cone collapse and organize callosal axon projections","volume":"7","author":"KY Wu","year":"2014","journal-title":"Sci. Signal"},{"issue":"34","key":"pone.0221440.ref027","doi-asserted-by":"crossref","first-page":"10963","DOI":"10.1523\/JNEUROSCI.23-34-10963.2003","article-title":"Corpus callosum deficiency in transgenic mice expressing a truncated ephrin-A receptor","volume":"23","author":"Z Hu","year":"2003","journal-title":"J Neurosci"},{"issue":"3","key":"pone.0221440.ref028","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1523\/JNEUROSCI.3162-05.2006","article-title":"Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain","volume":"26","author":"SW Mendes","year":"2006","journal-title":"J. Neurosci"},{"issue":"5912","key":"pone.0221440.ref029","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1126\/science.1165187","article-title":"Draxin, a repulsive guidance protein for spinal cord and forebrain commissures","volume":"323","author":"SM Islam","year":"2009","journal-title":"Science"},{"issue":"6627","key":"pone.0221440.ref030","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/386796a0","article-title":"Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene","volume":"386","author":"A Fazeli","year":"1997","journal-title":"Nature"},{"issue":"21","key":"pone.0221440.ref031","doi-asserted-by":"crossref","first-page":"5840","DOI":"10.1523\/JNEUROSCI.1175-06.2006","article-title":"The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum","volume":"26","author":"TR Keeble","year":"2006","journal-title":"J Neurosci"},{"issue":"11","key":"pone.0221440.ref032","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1242\/dev.02379","article-title":"Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain","volume":"133","author":"W Andrews","year":"2006","journal-title":"Development"},{"issue":"1","key":"pone.0221440.ref033","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/cne.902100103","article-title":"Axonal guidance during development of the great cerebral commissures: descriptive and experimental studies, in vivo, on the role of preformed glial pathways","volume":"210","author":"J Silver","year":"1982","journal-title":"J Comp Neurol"},{"issue":"13","key":"pone.0221440.ref034","doi-asserted-by":"crossref","first-page":"2929","DOI":"10.1242\/dev.00514","article-title":"The glial sling is a migratory population of developing neurons","volume":"130","author":"T Shu","year":"2003","journal-title":"Development"},{"issue":"3","key":"pone.0221440.ref035","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/cne.903280308","article-title":"Immunocytochemical demonstration of early appearing astroglial structures that form boundaries and pathways along axon tracts in the fetal brain","volume":"328","author":"J. Silver","year":"1993","journal-title":"J. Comp. Neurol"},{"issue":"24","key":"pone.0221440.ref036","doi-asserted-by":"crossref","first-page":"5043","DOI":"10.1242\/dev.125.24.5043","article-title":"Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections","volume":"125","author":"D Bagnard","year":"1998","journal-title":"Development"},{"issue":"3","key":"pone.0221440.ref037","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1523\/JNEUROSCI.20-03-01030.2000","article-title":"Spatial distributions of guidance molecules regulate chemorepulsion and chemoattraction of growth cones","volume":"20","author":"D Bagnard","year":"2000","journal-title":"J Neurosci"},{"issue":"1","key":"pone.0221440.ref038","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0092-8674(00)80062-8","article-title":"Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors","volume":"99","author":"T Takahashi","year":"1999","journal-title":"Cell"},{"issue":"1","key":"pone.0221440.ref039","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0092-8674(00)80063-X","article-title":"Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates","volume":"99","author":"L Tamagnone","year":"1999","journal-title":"Cell"},{"issue":"3","key":"pone.0221440.ref040","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0896-6273(00)80371-2","article-title":"Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III","volume":"19","author":"H Chen","year":"1997","journal-title":"Neuron"},{"issue":"4","key":"pone.0221440.ref041","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S0092-8674(00)80534-6","article-title":"Neuropilin is a receptor for the axonal chemorepellent Semaphorin III","volume":"90","author":"Z He","year":"1997","journal-title":"Cell"},{"issue":"4","key":"pone.0221440.ref042","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0092-8674(00)80535-8","article-title":"Neuropilin is a semaphorin III receptor","volume":"90","author":"AL Kolodkin","year":"1997","journal-title":"Cell"},{"issue":"1","key":"pone.0221440.ref043","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0959-4388(03)00003-5","article-title":"Semaphorin junction making tracks toward neural connectivity","volume":"13","author":"RJ Pasterkamp","year":"2003","journal-title":"Curr Opin Neurobiol"},{"issue":"2","key":"pone.0221440.ref044","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0896-6273(01)00216-1","article-title":"Plexina1 autoinhibition by the plexin sema domain","volume":"29","author":"T Takahashi","year":"2001","journal-title":"Neuron"},{"issue":"1\u20132","key":"pone.0221440.ref045","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0925-4773(00)00269-0","article-title":"Plexin\/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A","volume":"93","author":"B Rohm","year":"2000","journal-title":"Mech Dev"},{"issue":"11","key":"pone.0221440.ref046","doi-asserted-by":"crossref","first-page":"6608","DOI":"10.1523\/JNEUROSCI.14-11-06608.1994","article-title":"Axons of early generated neurons in cingulate cortex pioneer the corpus callosum","volume":"14","author":"SE Koester","year":"1994","journal-title":"J Neurosci"},{"issue":"2","key":"pone.0221440.ref047","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/(SICI)1096-9861(19981019)400:2<197::AID-CNE3>3.0.CO;2-4","article-title":"Timing and origin of the first cortical axons to project through the corpus callosum and the subsequent emergence of callosal projection cells in mouse","volume":"400","author":"HS Ozaki","year":"1998","journal-title":"J Comp Neurol"},{"issue":"2","key":"pone.0221440.ref048","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/cne.1170","article-title":"A role for cingulate pioneering axons in the development of the corpus callosum","volume":"434","author":"BG Rash","year":"2001","journal-title":"J Comp Neurol"},{"issue":"39","key":"pone.0221440.ref049","doi-asserted-by":"crossref","first-page":"12343","DOI":"10.1523\/JNEUROSCI.6108-08.2009","article-title":"Novel subtype-specific genes identify distinct subpopulations of callosal projection neurons","volume":"29","author":"BJ Molyneaux","year":"2009","journal-title":"J Neurosci"},{"issue":"2","key":"pone.0221440.ref050","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0896-6273(00)00033-7","article-title":"Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance","volume":"27","author":"V Castellani","year":"2000","journal-title":"Neuron"},{"issue":"1","key":"pone.0221440.ref051","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.conb.2010.07.008","article-title":"Further tales of the midline","volume":"21","author":"A Ch\u00e9dotal","year":"2011","journal-title":"Curr Opin Neurobiol"},{"issue":"6","key":"pone.0221440.ref052","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/ncb1416","article-title":"Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis","volume":"8","author":"N Takegahara","year":"2006","journal-title":"Nat Cell Biol"},{"issue":"5","key":"pone.0221440.ref053","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.3892\/ijmm.2014.1690","article-title":"Plexin-A1 is required for Toll-like receptor-mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy","volume":"33","author":"T Ito","year":"2014","journal-title":"Int J Mol Med"},{"issue":"5","key":"pone.0221440.ref054","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1093\/cercor\/bhs395","article-title":"Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating Slit2-mediated repulsion","volume":"24","author":"T Fothergill","year":"2014","journal-title":"Cereb Cortex"},{"issue":"5","key":"pone.0221440.ref055","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1002\/cne.22536","article-title":"A molecular mechanism that regulates medially oriented axonal growth of upper layer neurons in the developing neocortex","volume":"519","author":"H Zhao","year":"2011","journal-title":"J Comp Neurol"},{"issue":"5","key":"pone.0221440.ref056","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/cne.22125","article-title":"Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice","volume":"516","author":"F Nakamura","year":"2009","journal-title":"J Comp Neurol"},{"issue":"3","key":"pone.0221440.ref057","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1093\/cercor\/bhs044","article-title":"Integration of opposing semaphorin guidance cues in cortical axons","volume":"23","author":"T Ruediger","year":"2013","journal-title":"Cereb Cortex"},{"issue":"4","key":"pone.0221440.ref058","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1101\/gad.542510","article-title":"A midline switch of receptor processing regulates commissural axon guidance in vertebrates","volume":"24","author":"H Nawabi","year":"2010","journal-title":"Genes Dev"},{"issue":"29","key":"pone.0221440.ref059","doi-asserted-by":"crossref","first-page":"E2714","DOI":"10.1073\/pnas.1310233110","article-title":"Axon position within the corpus callosum determines contralateral cortical projection","volume":"110","author":"J Zhou","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"pone.0221440.ref060","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1083\/jcb.201106113","article-title":"The vesicular SNARE Synaptobrevin is required for Semaphorin 3A axonal repulsion","volume":"196","author":"K Zylbersztejn","year":"2012","journal-title":"J Cell Biol"},{"key":"pone.0221440.ref061","doi-asserted-by":"crossref","first-page":"45359","DOI":"10.1038\/srep45359","article-title":"Proteome dynamics during postnatal mouse corpus callosum development","volume":"7","author":"AI Son","year":"2017","journal-title":"Sci Rep"},{"issue":"1","key":"pone.0221440.ref062","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S1534-5807(03)00169-2","article-title":"Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development","volume":"5","author":"C Gu","year":"2003","journal-title":"Dev Cell"},{"issue":"3","key":"pone.0221440.ref063","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.spen.2009.07.003","article-title":"Understanding the mechanisms of callosal development through the use of transgenic mouse models","volume":"16","author":"AL Donahoo","year":"2009","journal-title":"Semin Pediatr Neurol"},{"issue":"1","key":"pone.0221440.ref064","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1006\/dbio.1996.0207","article-title":"Mutation of the Emx-1 homeobox gene disrupts the corpus callosum","volume":"178","author":"M Qiu","year":"1996","journal-title":"Dev Biol"},{"issue":"1","key":"pone.0221440.ref065","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1242\/dev.124.1.101","article-title":"Emx1 and Emx2 functions in development of dorsal telencephalon","volume":"124","author":"M Yoshida","year":"1997","journal-title":"Development"},{"issue":"2","key":"pone.0221440.ref066","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1006\/bbrc.2000.3533","article-title":"Normal corpus callosum in Emx1 mutant mice with C57BL\/6 background","volume":"276","author":"H Guo","year":"2000","journal-title":"Biochem Biophys Res Commun"},{"issue":"8","key":"pone.0221440.ref067","doi-asserted-by":"crossref","first-page":"4656","DOI":"10.1073\/pnas.96.8.4656","article-title":"Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the beta-amyloid-precursor protein","volume":"96","author":"F Magara","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"pone.0221440.ref068","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3109\/01677068909167265","article-title":"Deficiency of the corpus callosum: incomplete penetrance and substrain differentiation in BALB\/c mice","volume":"5","author":"D Wahlsten","year":"1989","journal-title":"J Neurogenet"},{"issue":"1","key":"pone.0221440.ref069","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(74)90530-7","article-title":"Heritable aspects of anomalous myelinated fibre tracts in the forebrain of the laboratory mouse","volume":"68","author":"D Wahlsten","year":"1974","journal-title":"Brain Res"},{"issue":"9","key":"pone.0221440.ref070","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1007\/BF01954057","article-title":"Genetic and developmental defects of the mouse corpus callosum","volume":"45","author":"D Wahlsten","year":"1989","journal-title":"Experientia"},{"issue":"1","key":"pone.0221440.ref071","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3109\/01677068909167265","article-title":"Deficiency of the corpus callosum: incomplete penetrance and substrain differentiation in BALB\/c mice","volume":"5","author":"D Wahlsten","year":"1989","journal-title":"J Neurogenet"},{"issue":"1","key":"pone.0221440.ref072","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/oxfordjournals.jhered.a110781","article-title":"Inheritance of retarded forebrain commissure development in fetal mice: results from classical crosses and recombinant inbred strains","volume":"80","author":"D Wahlsten","year":"1989","journal-title":"J Hered"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0221440","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T02:13:37Z","timestamp":1664158417000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0221440"}},"subtitle":[],"editor":[{"given":"Brian","family":"Key","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,8,20]]},"references-count":72,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2019,8,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0221440","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,20]]}}}