{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:04:16Z","timestamp":1792677856971,"version":"4.5.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T00:00:00Z","timestamp":1570060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0223076","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T13:25:27Z","timestamp":1570109127000},"page":"e0223076","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":25,"title":["Isoniazid preventive therapy: Uptake, incidence of tuberculosis and survival among people living with HIV in Bulawayo, Zimbabwe"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1916-7313","authenticated-orcid":true,"given":"Saziso","family":"Nyathi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riitta A.","family":"Dlodlo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5420-2551","authenticated-orcid":true,"given":"Srinath","family":"Satyanarayana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kudakwashe C.","family":"Takarinda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannock","family":"Tweya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sithokozile","family":"Hove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronnie","family":"Matambo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winnie","family":"Mandewo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khulamuzi","family":"Nyathi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Sibanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony D.","family":"Harries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"pone.0223076.ref001","volume-title":"Global HIV and AIDS statistics\u20142018 fact sheet","author":"UNAIDS","year":"2018"},{"key":"pone.0223076.ref002","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1056\/NEJM198903023200901","article-title":"A Prospective Study of the Risk of Tuberculosis among Intravenous Drug Users with Human Immunodeficiency Virus Infection","volume":"320","author":"PA Selwyn","year":"1989","journal-title":"N Engl J Med"},{"key":"pone.0223076.ref003","volume-title":"Global TB Report","author":"World Health Organisation","year":"2017"},{"key":"pone.0223076.ref004","unstructured":"Joint United Nations Programme on HIV\/AIDS (UNAIDS). UNAIDS Data 2017. 2017. UNAIDS\/JC2910E"},{"key":"pone.0223076.ref005","doi-asserted-by":"crossref","first-page":"241","DOI":"10.5588\/ijtld.18.0207","article-title":"Challenges and opportunities to prevent tuberculosis in people living with HIV in low-income countries","volume":"23","author":"AD Harries","year":"2019","journal-title":"Int J Tuberc lung Dis"},{"key":"pone.0223076.ref006","doi-asserted-by":"crossref","first-page":"e1001270","DOI":"10.1371\/journal.pmed.1001270","article-title":"Antiretroviral Therapy for Prevention of Tuberculosis in Adults with HIV: A Systematic Review and Meta-Analysis","volume":"9","author":"AB Suthar","year":"2012","journal-title":"PLoS Med"},{"key":"pone.0223076.ref007","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1056\/NEJMoa1507198","article-title":"A Trial of Early Antiretrovirals and Isoniazid Preventive Therapy in Africa","volume":"373","year":"2015","journal-title":"N Engl J Med"},{"key":"pone.0223076.ref008","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/S0140-6736(14)60162-8","article-title":"Isoniazid plus antiretroviral therapy to prevent tuberculosis: a randomised double-blind, placebo-controlled trial","volume":"384","author":"MX Rangaka","year":"2014","journal-title":"Lancet (London, England)"},{"issue":"Suppl 5","key":"pone.0223076.ref009","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1097\/01.aids.0000391010.02774.6f","article-title":"Association of isoniazid preventive therapy with lower early mortality in individuals on antiretroviral therapy in a workplace programme","volume":"24","author":"S Charalambous","year":"2010","journal-title":"AIDS"},{"key":"pone.0223076.ref010","doi-asserted-by":"crossref","first-page":"e1080","DOI":"10.1016\/S2214-109X(17)30372-8","article-title":"Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial","volume":"5","author":"A Badje","year":"2017","journal-title":"Lancet Glob Heal"},{"key":"pone.0223076.ref011","volume-title":"WHO Guidelines on Intensified Tuberculosis Case Finding for People Living With HIV in Resource Constrained Settings","author":"World Health Organisation","year":"2012"},{"key":"pone.0223076.ref012","unstructured":"Health Services Department-City of Bulawayo. 2017 Annual Report. Bulawayo; 2017."},{"key":"pone.0223076.ref013","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1186\/s12889-016-3525-8","article-title":"Barriers in the implementation of isoniazid preventive therapy for people living with HIV in Northern Ethiopia: a mixed quantitative and qualitative study","volume":"16","author":"G Teklay","year":"2016","journal-title":"BMC Public Health"},{"key":"pone.0223076.ref014","unstructured":"Zimbabwe National Statistical Agency. Zimbabwe National Population Census Report 2012. Harare; 2014."},{"key":"pone.0223076.ref015","doi-asserted-by":"crossref","first-page":"55","DOI":"10.5588\/pha.16.0102","article-title":"Routine implementation of isoniazid preventive therapy in HIV-infected patients in seven pilot sites in Zimbabwe","volume":"7","author":"KC Takarinda","year":"2017","journal-title":"Public Heal action"},{"key":"pone.0223076.ref016","volume-title":"Global Health TB Report","author":"World Health Organisation","year":"2018"},{"key":"pone.0223076.ref017","unstructured":"Ministry of Health and Child Care. National TB and Leprosy Guidelines, Zimbabwe. 2017."},{"key":"pone.0223076.ref018","unstructured":"World Health Organisation. Adverse Events associated with the use of Isoniazid Preventive Therapy among people living with HIV. 2015."},{"key":"pone.0223076.ref019","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for reporting observational studies","volume":"12","author":"E von Elm","year":"2014","journal-title":"Int J Surg"},{"key":"pone.0223076.ref020","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/bmj.39335.541782.AD","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"335","author":"E von Elm","year":"2007","journal-title":"BMJ"},{"key":"pone.0223076.ref021","doi-asserted-by":"crossref","first-page":"e81376","DOI":"10.1371\/journal.pone.0081376","article-title":"Eligibility for Isoniazid Preventive Therapy in South African Gold Mines","volume":"8","author":"JJ Lewis","year":"2013","journal-title":"PLoS One"},{"key":"pone.0223076.ref022","doi-asserted-by":"crossref","first-page":"273","DOI":"10.5588\/ijtld.17.0370","article-title":"Completion of isoniazid preventive therapy among human immunodeficiency virus positive adults in urban Malawi","volume":"22","author":"D Thindwa","year":"2018","journal-title":"Int J Tuberc Lung Dis"},{"key":"pone.0223076.ref023","unstructured":"National Medicines and Therapeutics Policy Advisory Committee, And, Ministry of Health and Child Care. Guidelines for Antiretroviral Therapy for the Prevention and Treatment of HIV in Zimbabwe. Harare; 2016."},{"key":"pone.0223076.ref024","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1186\/s13104-015-1451-y","article-title":"Evaluation of the isoniazid preventive therapy (IPT) program in Shurugwi District, Midlands Province, Zimbabwe, January 2013 to August 2014","volume":"8","author":"A Makoni","year":"2015","journal-title":"BMC Res Notes"},{"key":"pone.0223076.ref025","article-title":"Completion of isoniazid preventive therapy among human immunodeficiency virus positive adults in urban Malawi","author":"D Thindwa","year":"2018","journal-title":"Int J Tuberc Lung Dis"},{"key":"pone.0223076.ref026","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1080\/09540121.2017.1283390","article-title":"\u201cIt\u2019s about my life\u201d: facilitators of and barriers to isoniazid preventive therapy completion among people living with HIV in rural South Africa","volume":"29","author":"KB Jacobson","year":"2017","journal-title":"AIDS Care"},{"key":"pone.0223076.ref027","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1186\/s12889-016-3525-8","article-title":"Barriers in the implementation of isoniazid preventive therapy for people living with HIV in Northern Ethiopia: a mixed quantitative and qualitative study","volume":"16","author":"G Teklay","year":"2016","journal-title":"BMC Public Heal"},{"key":"pone.0223076.ref028","doi-asserted-by":"crossref","first-page":"537","DOI":"10.5588\/ijtld.16.0775","article-title":"Implementing isoniazid preventive therapy in a tuberculosis treatment-experienced cohort on ART","volume":"21","author":"B Maharaj","year":"2017","journal-title":"Int J Tuberc Lung Dis"},{"key":"pone.0223076.ref029","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1186\/1471-2334-14-281","article-title":"Interventions to improve delivery of isoniazid preventive therapy: an overview of systematic reviews","volume":"14","author":"L V Adams","year":"2014","journal-title":"BMC Infect Dis"},{"key":"pone.0223076.ref030","doi-asserted-by":"crossref","first-page":"50","DOI":"10.5588\/pha.12.0011","article-title":"ART uptake, its timing and relation to anti-tuberculosis treatment outcomes among HIV-infected TB patients","volume":"2","author":"KC Takarinda","year":"2012","journal-title":"Public Heal Action"},{"key":"pone.0223076.ref031","doi-asserted-by":"crossref","DOI":"10.11604\/pamj.2018.30.32.12554","article-title":"Treatment outcome of tuberculosis among Human Immunodeficiency Virus positive patients in Eastern Ethiopia: a retrospective study","volume":"30","author":"F Weldegebreal","year":"2018","journal-title":"Pan Afr Med J"},{"key":"pone.0223076.ref032","doi-asserted-by":"crossref","first-page":"371","DOI":"10.5588\/ijtld.18.0378","article-title":"Provider barriers to the uptake of isoniazid preventive therapy among people living with HIV in Ethiopia","volume":"23","author":"J Lai","year":"2019","journal-title":"Int J Tuberc Lung Dis"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0223076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T17:37:53Z","timestamp":1588959473000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0223076"}},"subtitle":[],"editor":[{"given":"Kwasi","family":"Torpey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,10,3]]},"references-count":32,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0223076","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,3]]}}}