{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:41:20Z","timestamp":1783528880504,"version":"3.55.0"},"reference-count":92,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T00:00:00Z","timestamp":1570060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004337","name":"St. George's, University of London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004337","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0223297","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T17:38:41Z","timestamp":1570124321000},"page":"e0223297","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Disruption of white matter connectivity in chronic obstructive pulmonary disease"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6908-5079","authenticated-orcid":true,"given":"Catherine A.","family":"Spilling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Dodd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R.","family":"Barrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,10,3]]},"reference":[{"key":"pone.0223297.ref001","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1210\/er.2007-0034","article-title":"Cognitive Dysfunction and Diabetes Mellitus","volume":"29","author":"CT Kodl","year":"2008","journal-title":"Endocr Rev"},{"key":"pone.0223297.ref002","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-016-0745-9","article-title":"Cognition in chronic kidney disease: a systematic review and meta-analysis","volume":"14","author":"I Berger","year":"2016","journal-title":"BMC Med"},{"key":"pone.0223297.ref003","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/acr.23243","article-title":"Cognitive Impairment in Rheumatoid Arthritis: A Systematic Review","volume":"70","author":"T Meade","year":"2018","journal-title":"Arthritis Care Res"},{"key":"pone.0223297.ref004","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/1465-9921-11-122","article-title":"Characterisation of COPD heterogeneity in the ECLIPSE cohort","volume":"11","author":"A Agusti","year":"2010","journal-title":"Respir Res"},{"key":"pone.0223297.ref005","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13195-015-0116-3","article-title":"Lung disease as a determinant of cognitive decline and dementia","volume":"7","author":"JW Dodd","year":"2015","journal-title":"Alzheimers Res Ther"},{"key":"pone.0223297.ref006","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1111\/j.1532-5415.2012.04171.x","article-title":"Effect of Coexisting Chronic Obstructive Pulmonary Disease and Cognitive Impairment on Health Outcomes in Older Adults","volume":"60","author":"SS Chang","year":"2012","journal-title":"J Am Geriatr Soc"},{"key":"pone.0223297.ref007","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1378\/chest.112.6.1506","article-title":"Verbal memory impairment in COPD: its mechanisms and clinical relevance","volume":"112","author":"R Antonelli Incalzi","year":"1997","journal-title":"CHEST J"},{"key":"pone.0223297.ref008","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1136\/jnnp.2003.022012","article-title":"Arterial oxygen saturation, COPD, and cerebral small vessel disease","volume":"75","author":"EJ van Dijk","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"pone.0223297.ref009","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1164\/rccm.201303-0455OC","article-title":"Chronic obstructive pulmonary disease and cerebral microbleeds. The Rotterdam study","volume":"188","author":"L Lahousse","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"pone.0223297.ref010","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1164\/rccm.201202-0355OC","article-title":"Brain Structure and Function in Chronic Obstructive Pulmonary Disease: A Multimodal Cranial Magnetic Resonance Imaging Study","volume":"186","author":"JW Dodd","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"pone.0223297.ref011","doi-asserted-by":"crossref","DOI":"10.1186\/s12890-017-0435-1","article-title":"White matter lesions characterise brain involvement in moderate to severe chronic obstructive pulmonary disease, but cerebral atrophy does not","volume":"17","author":"CA Spilling","year":"2017","journal-title":"BMC Pulm Med"},{"key":"pone.0223297.ref012","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3109\/15412555.2012.752808","volume":"10","author":"CW Ryu","year":"2013","journal-title":"Microstructural change of the brain in chronic obstructive pulmonary disease"},{"key":"pone.0223297.ref013","doi-asserted-by":"crossref","first-page":"e000844","DOI":"10.1136\/bmjopen-2012-000844","article-title":"Grey and white matter abnormalities in chronic obstructive pulmonary disease: a case-control study","volume":"2","author":"H Zhang","year":"2012","journal-title":"BMJ Open"},{"key":"pone.0223297.ref014","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1212\/WNL.0000000000004594","article-title":"Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease","volume":"89","author":"EA Zeestraten","year":"2017","journal-title":"Neurology"},{"key":"pone.0223297.ref015","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.3174\/ajnr.A0555","article-title":"Whole-Brain Histogram and Voxel-Based Analyses of Diffusion Tensor Imaging in Patients with Leukoaraiosis: Correlation with Motor and Cognitive Impairment","volume":"28","author":"RD Nave","year":"2007","journal-title":"Am J Neuroradiol"},{"key":"pone.0223297.ref016","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/mrm.21461","article-title":"Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease","volume":"59","author":"A Nitkunan","year":"2008","journal-title":"Magn Reson Med"},{"key":"pone.0223297.ref017","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/ana.410280502","article-title":"Large-scale neurocognitive networks and distributed processing for attention, language and memory","volume":"28","author":"M-M Mesulam","year":"1990","journal-title":"Ann Neurol"},{"key":"pone.0223297.ref018","doi-asserted-by":"crossref","first-page":"1238411","DOI":"10.1126\/science.1238411","article-title":"Structural and Functional Brain Networks: From Connections to Cognition","volume":"342","author":"H-J Park","year":"2013","journal-title":"Science"},{"key":"pone.0223297.ref019","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2010.00200","article-title":"Modular and Hierarchically Modular Organization of Brain Networks","volume":"4","author":"D Meunier","year":"2010","journal-title":"Front Neurosci"},{"key":"pone.0223297.ref020","article-title":"The economy of brain network organization","author":"E Bullmore","year":"2012","journal-title":"Nat Rev Neurosci"},{"key":"pone.0223297.ref021","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1212\/WNL.0000000000000612","article-title":"Structural network efficiency is associated with cognitive impairment in small-vessel disease","volume":"83","author":"AJ Lawrence","year":"2014","journal-title":"Neurology"},{"key":"pone.0223297.ref022","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1164\/rccm.201701-0218PP","article-title":"Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary","volume":"195","author":"CF Vogelmeier","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"key":"pone.0223297.ref023","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1164\/rccm.200701-067OC","article-title":"Arterial stiffness and osteoporosis in chronic obstructive pulmonary disease","volume":"175","author":"R Sabit","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"pone.0223297.ref024","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1161\/01.STR.25.1.40","article-title":"Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study","volume":"25","author":"R B D\u2019Agostino","year":"1994","journal-title":"Stroke"},{"key":"pone.0223297.ref025","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"ME Charlson","year":"1987","journal-title":"J Chronic Dis"},{"key":"pone.0223297.ref026","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1164\/ajrccm\/145.6.1321","article-title":"A self-complete measure of health status for chronic airflow limitation. The St. George\u2019s Respiratory Questionnaire","volume":"145","author":"PW Jones","year":"1992","journal-title":"Am Rev Respir Dis"},{"key":"pone.0223297.ref027","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"AS Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"pone.0223297.ref028","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.neuroimage.2011.09.015","article-title":"FSL","volume":"62","author":"M Jenkinson","year":"2012","journal-title":"NeuroImage"},{"key":"pone.0223297.ref029","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/hbm.10062","article-title":"Fast robust automated brain extraction","volume":"17","author":"SM Smith","year":"2002","journal-title":"Hum Brain Mapp"},{"key":"pone.0223297.ref030","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.nicl.2015.07.002","article-title":"Characterising the grey matter correlates of leukoaraiosis in cerebral small vessel disease","volume":"9","author":"C Lambert","year":"2015","journal-title":"NeuroImage Clin"},{"key":"pone.0223297.ref031","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nrn2575","article-title":"Complex brain networks: graph theoretical analysis of structural and functional systems","volume":"10","author":"E Bullmore","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"pone.0223297.ref032","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain","volume":"15","author":"N Tzourio-Mazoyer","year":"2002","journal-title":"NeuroImage"},{"key":"pone.0223297.ref033","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroimage.2009.06.060","article-title":"Accurate and robust brain image alignment using boundary-based registration","volume":"48","author":"DN Greve","year":"2009","journal-title":"NeuroImage"},{"key":"pone.0223297.ref034","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1097\/00004728-199803000-00032","article-title":"Enhancement of MR images using registration for signal averaging","volume":"22","author":"CJ Holmes","year":"1998","journal-title":"J Comput Assist Tomogr"},{"key":"pone.0223297.ref035","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1016\/j.neuroimage.2010.09.025","article-title":"A reproducible evaluation of ANTs similarity metric performance in brain image registration","volume":"54","author":"BB Avants","year":"2011","journal-title":"NeuroImage"},{"key":"pone.0223297.ref036","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.neuroimage.2010.07.024","article-title":"Track-density imaging (TDI): super-resolution white matter imaging using whole-brain track-density mapping","volume":"53","author":"F Calamante","year":"2010","journal-title":"NeuroImage"},{"key":"pone.0223297.ref037","doi-asserted-by":"crossref","first-page":"e597","DOI":"10.1371\/journal.pone.0000597","article-title":"Mapping Human Whole-Brain Structural Networks with Diffusion MRI","volume":"2","author":"P Hagmann","year":"2007","journal-title":"PLoS ONE"},{"key":"pone.0223297.ref038","doi-asserted-by":"crossref","first-page":"15775","DOI":"10.1523\/JNEUROSCI.3539-11.2011","article-title":"Rich-club organization of the human connectome","volume":"31","author":"MP van den Heuvel","year":"2011","journal-title":"J Neurosci Off J Soc Neurosci"},{"key":"pone.0223297.ref039","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","article-title":"Complex network measures of brain connectivity: Uses and interpretations","volume":"52","author":"M Rubinov","year":"2010","journal-title":"NeuroImage"},{"key":"pone.0223297.ref040","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1126\/science.1065103","article-title":"Specificity and stability in topology of protein networks","volume":"296","author":"S Maslov","year":"2002","journal-title":"Science"},{"key":"pone.0223297.ref041","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.neuroimage.2015.05.046","article-title":"The (in)stability of functional brain network measures across thresholds","volume":"118","author":"KA Garrison","year":"2015","journal-title":"NeuroImage"},{"key":"pone.0223297.ref042","doi-asserted-by":"crossref","DOI":"10.3389\/fncom.2014.00051","article-title":"Statistical network analysis for functional MRI: summary networks and group comparisons","volume":"8","author":"CE Ginestet","year":"2014","journal-title":"Front Comput Neurosci"},{"key":"pone.0223297.ref043","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.neuroimage.2015.05.011","article-title":"Overcoming the effects of false positives and threshold bias in graph theoretical analyses of neuroimaging data","volume":"118","author":"M Drakesmith","year":"2015","journal-title":"NeuroImage"},{"key":"pone.0223297.ref044","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1002\/hbm.22796","article-title":"Schizophrenia-like topological changes in the structural connectome of individuals with subclinical psychotic experiences: Connectome Changes in Subclinical Psychosis","volume":"36","author":"M Drakesmith","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"pone.0223297.ref045","first-page":"512","article-title":"Small-world brain networks","volume":"12","author":"DS Bassett","year":"2006","journal-title":"Neurosci Rev J Bringing Neurobiol Neurol Psychiatry"},{"key":"pone.0223297.ref046","article-title":"White matter integrity disruptions associated with cognitive impairments in type 2 diabetes patients","author":"J Zhang","year":"2014","journal-title":"Diabetes"},{"key":"pone.0223297.ref047","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1007\/s00125-012-2488-2","article-title":"Diffusion tensor imaging in type 1 diabetes: decreased white matter integrity relates to cognitive functions","volume":"55","author":"E van Duinkerken","year":"2012","journal-title":"Diabetologia"},{"key":"pone.0223297.ref048","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.brainres.2009.08.058","article-title":"Pattern of normal age-related regional differences in white matter microstructure is modified by vascular risk","volume":"1297","author":"KM Kennedy","year":"2009","journal-title":"Brain Res"},{"key":"pone.0223297.ref049","article-title":"Brain abnormalities in children and adolescents with chronic kidney disease","author":"M Matsuda-Abedini","year":"2018","journal-title":"Pediatr Res"},{"key":"pone.0223297.ref050","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3233\/JAD-160834","article-title":"Association of Kidney Function Biomarkers with Brain MRI Findings: The BRINK Study","volume":"55","author":"P Vemuri","year":"2017","journal-title":"J Alzheimers Dis JAD"},{"key":"pone.0223297.ref051","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S1474-4422(13)70060-7","article-title":"Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging","volume":"12","author":"JM Wardlaw","year":"2013","journal-title":"Lancet Neurol"},{"key":"pone.0223297.ref052","first-page":"1","article-title":"The unique alterations of hippocampus and cognitive impairment in chronic obstructive pulmonary disease","volume":"14","author":"J Li","year":"2013","journal-title":"Respir Res"},{"key":"pone.0223297.ref053","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1378\/chest.15-0027","article-title":"Structural Brain Changes in Patients With COPD","volume":"149","author":"RW Esser","year":"2016","journal-title":"Chest"},{"key":"pone.0223297.ref054","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s12640-016-9690-9","article-title":"Altered Gray Matter Volume in Stable Chronic Obstructive Pulmonary Disease with Subclinical Cognitive Impairment: an Exploratory Study","volume":"31","author":"C Wang","year":"2017","journal-title":"Neurotox Res"},{"key":"pone.0223297.ref055","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1378\/chest.116.1.150","article-title":"Lower pulmonary function and cerebral subclinical abnormalities detected by MRI: the Atherosclerosis Risk in Communities study","volume":"116","author":"D Liao","year":"1999","journal-title":"Chest"},{"key":"pone.0223297.ref056","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00234-013-1157-6","article-title":"Correlation between pulmonary function and brain volume in healthy elderly subjects","volume":"55","author":"Y Taki","year":"2013","journal-title":"Neuroradiology"},{"key":"pone.0223297.ref057","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1159\/000091438","article-title":"Pulmonary Function, Cognitive Impairment and Brain Atrophy in a Middle-Aged Community Sample","volume":"21","author":"PS Sachdev","year":"2006","journal-title":"Dement Geriatr Cogn Disord"},{"key":"pone.0223297.ref058","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1148\/radiol.2371041496","article-title":"Brain white matter hyperintensities: relative importance of vascular risk factors in nondemented elderly people","volume":"237","author":"AD Murray","year":"2005","journal-title":"Radiology"},{"key":"pone.0223297.ref059","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1161\/STROKEAHA.107.513176","article-title":"Progression of Cerebral Small Vessel Disease in Relation to Risk Factors and Cognitive Consequences: Rotterdam Scan Study","volume":"39","author":"EJ van Dijk","year":"2008","journal-title":"Stroke"},{"key":"pone.0223297.ref060","doi-asserted-by":"crossref","first-page":"c3666","DOI":"10.1136\/bmj.c3666","article-title":"The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis","volume":"341","author":"S Debette","year":"2010","journal-title":"BMJ"},{"key":"pone.0223297.ref061","article-title":"Chronic obstructive pulmonary disease as a cardiovascular risk factor. Results of a case–control study (CONSISTE study)","volume":"679","author":"P Lucas","year":"2012","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"pone.0223297.ref062","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/j.rmed.2015.07.014","article-title":"Chronic obstructive pulmonary disease and cerebrovascular disease: A comprehensive review","volume":"109","author":"L Lahousse","year":"2015","journal-title":"Respir Med"},{"key":"pone.0223297.ref063","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/hbm.23032","article-title":"Structural network connectivity and cognition in cerebral small vessel disease: Structural Network and Cognition","volume":"37","author":"AM Tuladhar","year":"2016","journal-title":"Hum Brain Mapp"},{"key":"pone.0223297.ref064","article-title":"Prediction of Conversion from Mild Cognitive Impairment to Alzheimer\u2019s Disease Using MRI and Structural Network Features","volume":"8","author":"R Wei","year":"2016","journal-title":"Front Aging Neurosci"},{"key":"pone.0223297.ref065","first-page":"2605","article-title":"Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study","volume":"141","author":"AJC Eijlers","year":"2018","journal-title":"Brain"},{"key":"pone.0223297.ref066","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1212\/WNL.0000000000004594","article-title":"Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease","volume":"89","author":"EA Zeestraten","year":"2017","journal-title":"Neurology"},{"key":"pone.0223297.ref067","doi-asserted-by":"crossref","first-page":"e1898","DOI":"10.1212\/WNL.0000000000005551","article-title":"Longitudinal decline in structural networks predicts dementia in cerebral small vessel disease","volume":"90","author":"AJ Lawrence","year":"2018","journal-title":"Neurology"},{"key":"pone.0223297.ref068","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2016.00292","article-title":"Global Efficiency of Structural Networks Mediates Cognitive Control in Mild Cognitive Impairment","volume":"8","author":"R Berlot","year":"2016","journal-title":"Front Aging Neurosci"},{"key":"pone.0223297.ref069","doi-asserted-by":"crossref","first-page":"101712","DOI":"10.1016\/j.nicl.2019.101712","article-title":"Structural brain network measures are superior to vascular burden scores in predicting early cognitive impairment in post stroke patients with small vessel disease","volume":"22","author":"J Du","year":"2019","journal-title":"NeuroImage Clin"},{"key":"pone.0223297.ref070","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1037\/0894-4105.7.3.273","article-title":"Brain reserve capacity on symptom onset after brain injury: A formulation and review of evidence for threshold theory","volume":"7","author":"P Satz","year":"1993","journal-title":"Neuropsychology"},{"key":"pone.0223297.ref071","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1017\/S1355617702813248","article-title":"What is cognitive reserve? Theory and research application of the reserve concept","volume":"8","author":"Y Stern","year":"2002","journal-title":"J Int Neuropsychol Soc"},{"key":"pone.0223297.ref072","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1016\/j.neuropsychologia.2009.03.004","article-title":"Cognitive reserve\u2606","volume":"47","author":"Y Stern","year":"2009","journal-title":"Neuropsychologia"},{"key":"pone.0223297.ref073","volume-title":"Neuropsychological Assessment","author":"D. Lezak M","year":"2004"},{"key":"pone.0223297.ref074","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1002\/gps.1205","article-title":"Intracranial volume in mild cognitive impairment, Alzheimer\u2019s disease and vascular dementia: evidence for brain reserve?","volume":"19","author":"H Wolf","year":"2004","journal-title":"Int J Geriatr Psychiatry"},{"key":"pone.0223297.ref075","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1183\/09031936.00125109","article-title":"Cognitive function in COPD","volume":"35","author":"JW Dodd","year":"2010","journal-title":"European Respiratory Journal"},{"key":"pone.0223297.ref076","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s11571-017-9449-x","article-title":"The effects of depression, anxiety and sleep disturbances on cognitive impairment in patients with chronic obstructive pulmonary disease","volume":"11","author":"YG Aras","year":"2017","journal-title":"Cogn Neurodyn"},{"key":"pone.0223297.ref077","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.sleep.2011.12.007","article-title":"Disturbed Sleep among COPD Patients is Longitudinally Associated with Mortality and Adverse COPD Outcomes","volume":"13","author":"TA Omachi","year":"2012","journal-title":"Sleep Med"},{"key":"pone.0223297.ref078","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.4187\/respcare.04403","article-title":"Factors Influencing Cognitive Function in Subjects With COPD","volume":"61","author":"E Dag","year":"2016","journal-title":"Respiratory Care"},{"key":"pone.0223297.ref079","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1037\/0278-6133.22.6.598","article-title":"Cognitive and psychological outcomes of exercise in a 1-year follow-up study of patients with chronic obstructive pulmonary disease","volume":"22","author":"CF Emery","year":"2003","journal-title":"Health Psychol"},{"key":"pone.0223297.ref080","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jad.2017.05.039","article-title":"Structural network connectivity impairment and depressive symptoms in cerebral small vessel disease","volume":"220","author":"X Xie","year":"2017","journal-title":"J Affect Disord"},{"key":"pone.0223297.ref081","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.drugalcdep.2012.09.013","article-title":"Heavy smokers show abnormal microstructural integrity in the anterior corpus callosum: A diffusion tensor imaging study with tract-based spatial statistics","volume":"129","author":"F Lin","year":"2013","journal-title":"Drug Alcohol Depend"},{"key":"pone.0223297.ref082","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s12031-015-0550-5","article-title":"Microstructural White Matter Abnormalities and Cognitive Dysfunction in Subcortical Ischemic Vascular Disease: an Atlas-Based Diffusion Tensor Analysis Study","volume":"56","author":"L Lin","year":"2015","journal-title":"J Mol Neurosci MN"},{"key":"pone.0223297.ref083","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3174\/ajnr.A3235","article-title":"Reduced regional gray matter volume in patients with chronic obstructive pulmonary disease: a voxel-based morphometry study","volume":"34","author":"H Zhang","year":"2013","journal-title":"Am J Neuroradiol"},{"key":"pone.0223297.ref084","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.nicl.2018.06.025","article-title":"The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients","volume":"19","author":"R Heinen","year":"2018","journal-title":"NeuroImage Clin"},{"key":"pone.0223297.ref085","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S1053-8119(02)00042-3","article-title":"From diffusion tractography to quantitative white matter tract measures: a reproducibility study","volume":"18","author":"O Ciccarelli","year":"2003","journal-title":"NeuroImage"},{"key":"pone.0223297.ref086","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.neuroimage.2006.09.018","article-title":"Probabilistic diffusion tractography with multiple fibre orientations: What can we gain?","volume":"34","author":"TEJ Behrens","year":"2007","journal-title":"NeuroImage"},{"key":"pone.0223297.ref087","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/j.neuroimage.2011.08.043","article-title":"How and how not to correct for CSF-contamination in diffusion MRI","volume":"59","author":"C Metzler-Baddeley","year":"2012","journal-title":"NeuroImage"},{"key":"pone.0223297.ref088","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuroimage.2014.01.031","article-title":"CSF contamination contributes to apparent microstructural alterations in mild cognitive impairment","volume":"92","author":"R Berlot","year":"2014","journal-title":"NeuroImage"},{"key":"pone.0223297.ref089","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.media.2013.03.009","article-title":"Tractometer: towards validation of tractography pipelines","volume":"17","author":"M-A C\u00f4t\u00e9","year":"2013","journal-title":"Med Image Anal"},{"key":"pone.0223297.ref090","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.neuroimage.2004.07.037","article-title":"Direct estimation of the fiber orientation density function from diffusion-weighted MRI data using spherical deconvolution","volume":"23","author":"J-D Tournier","year":"2004","journal-title":"NeuroImage"},{"key":"pone.0223297.ref091","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1016\/j.neuroimage.2007.02.016","article-title":"Robust determination of the fibre orientation distribution in diffusion MRI: non-negativity constrained super-resolved spherical deconvolution","volume":"35","author":"J-D Tournier","year":"2007","journal-title":"NeuroImage"},{"key":"pone.0223297.ref092","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.3171\/2013.2.JNS121294","article-title":"White matter fiber tractography: why we need to move beyond DTI","volume":"118","author":"S Farquharson","year":"2013","journal-title":"J Neurosurg"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0223297","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T17:07:52Z","timestamp":1589044072000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0223297"}},"subtitle":[],"editor":[{"given":"Niels","family":"Bergsland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,10,3]]},"references-count":92,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0223297","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,3]]}}}