{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:02:46Z","timestamp":1780484566923,"version":"3.54.1"},"reference-count":20,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:00:00Z","timestamp":1571356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0223805","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T17:45:02Z","timestamp":1571420702000},"page":"e0223805","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Hepatopulmonary syndrome has low prevalence of pulmonary vascular abnormalities on chest computed tomography"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9828-8107","authenticated-orcid":true,"given":"Luciano","family":"Folador","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe S.","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana F.","family":"Zampieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betina C.","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marli M.","family":"Knorst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo B.","family":"Gazzana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,10,18]]},"reference":[{"key":"pone.0223805.ref001","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1183\/09031936.04.00010904","article-title":"Pulmonary\u2013Hepatic vascular Disorders (PHD)","volume":"24","author":"R Rodriguez-Roisin","year":"2004","journal-title":"Eur Respir J"},{"key":"pone.0223805.ref002","doi-asserted-by":"crossref","first-page":"5728","DOI":"10.3748\/wjg.v22.i25.5728","article-title":"Hepatopulmonary syndrome: What we know and what we would like to know","volume":"22","author":"I Grilo-Bensusan","year":"2016","journal-title":"World J Gastroenterol"},{"key":"pone.0223805.ref003","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1136\/gut.51.6.853","article-title":"Hepatopulmonary syndrome: prevalence and predictive value of various cut offs for arterial oxygenation and their clinical consequences","volume":"51","author":"P Schenk","year":"2002","journal-title":"Gut"},{"key":"pone.0223805.ref004","doi-asserted-by":"crossref","first-page":"42","DOI":"10.4065\/79.1.42","article-title":"Frequency, clinical characteristics, and respiratory parameters of hepatopulmonary syndrome","volume":"79","author":"BL Lima","year":"2004","journal-title":"Mayo Clin Proc"},{"key":"pone.0223805.ref005","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.3748\/wjg.v24.i12.1285","article-title":"Review article: Update on current and emergent data on hepatopulmonary syndrome","volume":"24","author":"S Soulaidopoulos","year":"2018","journal-title":"World J Gastroenterol"},{"key":"pone.0223805.ref006","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/S0016-5085(03)01207-1","article-title":"Prognostic significance of the hepatopulmonary syndrome in patients with cirrhosis","volume":"125","author":"P Schenk","year":"2003","journal-title":"Gastroenterology"},{"key":"pone.0223805.ref007","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.2214\/ajr.166.6.8633451","article-title":"The hepatopulmonary syndrome: Radiologic findings in 10 patients","volume":"166","author":"HP Mcadams","year":"1996","journal-title":"AJR Am J Roentgenol"},{"key":"pone.0223805.ref008","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/01.mcg.0000190775.57903.86","article-title":"Evaluation of intrapulmonary vascular dilatations with high-resolution computed thorax tomography in patients with hepatopulmonary syndrome","volume":"40","author":"D K\u00f6ksal","year":"2006","journal-title":"J Clin Gastroenterol"},{"key":"pone.0223805.ref009","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1148\/radiology.211.2.r99ma46549","article-title":"Hypoxemia and liver cirrhosis (hepatopulmonary syndrome) in eight patients: Comparison of the central and peripheral pulmonary vasculature","volume":"211","author":"K Lee","year":"1999","journal-title":"Radiology"},{"key":"pone.0223805.ref010","first-page":"1","article-title":"CT scan does not differentiate patients with hepatopulmonary syndrome from other patients with liver disease","volume":"11","author":"YA Chen","year":"2016","journal-title":"PLoS One"},{"key":"pone.0223805.ref011","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1148\/rg.2018170046","article-title":"Approach to pulmonary hypertension: From CT to clinical diagnosis","volume":"38","author":"F Aluja Jaramillo","year":"2018","journal-title":"Radiographics"},{"key":"pone.0223805.ref012","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1148\/rg.293085093","article-title":"Thoracic complications of liver cirrhosis","volume":"29","author":"YK Kim","year":"2009","journal-title":"Radiographics"},{"key":"pone.0223805.ref013","first-page":"515","article-title":"Hepatopulmonary syndrome. Clinical observations and lack of therapeutic response to somatostatin analogue","volume":"104","author":"MJ Krowka","year":"1993","journal-title":"Chest"},{"key":"pone.0223805.ref014","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"JR Landis","year":"1977","journal-title":"Biometrics"},{"key":"pone.0223805.ref015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0272-5231(05)70295-1","article-title":"Structural and pathologic changes in the lung vasculature in chronic liver disease","volume":"17","author":"DE Schraufnagel","year":"1996","journal-title":"Clin Chest Med"},{"key":"pone.0223805.ref016","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1148\/radiology.161.3.3786710","article-title":"Centrilobular lesions of the lung: Demonstration by high-resolution CT and pathologic correlation","volume":"161","author":"K Murata","year":"1986","journal-title":"Radiology"},{"key":"pone.0223805.ref017","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00004728-199505000-00005","article-title":"Normal bronchial and pulmonary arterial diameters measured by thin section CT","volume":"19","author":"SJ Kim","year":"1995","journal-title":"J Comput Assist Tomogr"},{"key":"pone.0223805.ref018","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1148\/radiol.13122665","article-title":"Intra and interobserver variability in CT measurements in oncology","volume":"269","author":"A McErlean","year":"2013","journal-title":"Radiology"},{"key":"pone.0223805.ref019","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.rcl.2009.01.001","article-title":"MDC T of the airways: Technique and normal results","volume":"47","author":"C Beigelman-Aubry","year":"2009","journal-title":"Radiol Clin North Am"},{"key":"pone.0223805.ref020","doi-asserted-by":"crossref","first-page":"5736","DOI":"10.1118\/1.4963214","article-title":"Automatic airway\u2013artery analysis on lung CT to quantify airway wall thickening and bronchiectasis","volume":"43","author":"A Perez-Rovira","year":"2016","journal-title":"Med Phys"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0223805","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T15:09:56Z","timestamp":1589036996000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0223805"}},"subtitle":[],"editor":[{"given":"Raffaele","family":"Serra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,10,18]]},"references-count":20,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0223805","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,18]]}}}