{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T15:39:07Z","timestamp":1772206747051,"version":"3.50.1"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01EB020407"],"award-info":[{"award-number":["R01EB020407"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01EB006841"],"award-info":[{"award-number":["R01EB006841"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["P20GM103472"],"award-info":[{"award-number":["P20GM103472"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["P30GM122734"],"award-info":[{"award-number":["P30GM122734"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Science Foundation","award":["1539067"],"award-info":[{"award-number":["1539067"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0224744","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T13:32:04Z","timestamp":1576071124000},"page":"e0224744","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["Whole brain polarity regime dynamics are significantly disrupted in schizophrenia and correlate strongly with network connectivity measures"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4679-7567","authenticated-orcid":true,"given":"Robyn L.","family":"Miller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Godfrey","family":"Pearlson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vince D.","family":"Calhoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"pone.0224744.ref001","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.neuroimage.2017.09.020","article-title":"Replicability of time-varying connectivity patterns in large resting state fMRI samples","volume":"163","author":"A Abrol","year":"2017","journal-title":"Neuroimage"},{"issue":"3","key":"pone.0224744.ref002","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/cercor\/bhs352","article-title":"Tracking whole-brain connectivity dynamics in the resting state","volume":"24","author":"E Allen","year":"2014","journal-title":"Cereb Cortex"},{"issue":"2","key":"pone.0224744.ref003","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.neuron.2014.10.015","article-title":"The chronnectome: time-varying connectivity networks as the next frontier in fMRI data discovery","volume":"84","author":"VD Calhoun","year":"2014","journal-title":"Neuron"},{"key":"pone.0224744.ref004","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.nicl.2014.07.003","article-title":"Dynamic functional connectivity analysis reveals transient states of dysconnectivity in schizophrenia","volume":"5","author":"E Damaraju","year":"2014","journal-title":"Neuroimage: Clinical"},{"key":"pone.0224744.ref005","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.neuroimage.2015.11.055","article-title":"Can sliding-window correlations reveal dynamic functional connectivity in resting-state fMRI?","volume":"127","author":"R Hindriks","year":"2016","journal-title":"Neuroimage"},{"key":"pone.0224744.ref006","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.neuroimage.2013.05.079","article-title":"Dynamic functional connectivity: promises, issues, and interpretations","volume":"80","author":"RM Hutchison","year":"2013","journal-title":"NeuroImage"},{"key":"pone.0224744.ref007","article-title":"On the Stability of BOLD fMRI Correlations","author":"TO Laumann","year":"2016","journal-title":"Cereb Cortex"},{"key":"pone.0224744.ref008","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2018.00551","article-title":"Resting-State fMRI Dynamics and Null Models: Perspectives, Sampling Variability, and Simulations","volume":"12","author":"RL Miller","year":"2018","journal-title":"Frontiers in Neuroscience"},{"key":"pone.0224744.ref009","article-title":"The dynamic functional connectome: State-of-the-art and perspectives","author":"MG Preti","year":"2016","journal-title":"Neuroimage"},{"key":"pone.0224744.ref010","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fneur.2015.00010","article-title":"Multimodal imaging of dynamic functional connectivity","volume":"6","author":"E Tagliazucchi","year":"2015","journal-title":"Front Neurol"},{"key":"pone.0224744.ref011","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.neuroimage.2017.05.050","article-title":"Whole-brain connectivity dynamics reflect both task-specific and individual-specific modulation: A multitask study","volume":"180","author":"H Xie","year":"2018","journal-title":"Neuroimage"},{"key":"pone.0224744.ref012","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.neuroimage.2015.03.047","article-title":"Towards a statistical test for functional connectivity dynamics","volume":"114","author":"A Zalesky","year":"2015","journal-title":"Neuroimage"},{"issue":"8","key":"pone.0224744.ref013","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1089\/brain.2017.0543","article-title":"Time-Resolved Resting-State Functional Magnetic Resonance Imaging Analysis: Current Status, Challenges, and New Directions","volume":"7","author":"S Keilholz","year":"2017","journal-title":"Brain Connect"},{"issue":"10","key":"pone.0224744.ref014","doi-asserted-by":"crossref","first-page":"3058","DOI":"10.1002\/hbm.24580","article-title":"The spatial chronnectome reveals a dynamic interplay between functional segregation and integration","volume":"40","author":"A Iraji","year":"2019","journal-title":"Human brain mapping"},{"issue":"6","key":"pone.0224744.ref015","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1002\/hbm.24505","article-title":"Spatial dynamics within and between brain functional domains: A hierarchical approach to study time-varying brain function","volume":"40","author":"A Iraji","year":"2019","journal-title":"Human brain mapping"},{"key":"pone.0224744.ref016","unstructured":"Miller RL, Calhoun VD. Schizophrenia Signicantly Impacts Network Spatial Map Dynamics and Spatial Network Connectivity. 25th Annual Meeting of the Organization for Human Brain Mapping Rome Italy 2019."},{"key":"pone.0224744.ref017","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2015.00203","article-title":"Multidimensional frequency domain analysis of full-volume fMRI reveals significant effects of age, gender, and mental illness on the spatiotemporal organization of resting-state brain activity","volume":"9","author":"RL Miller","year":"2015","journal-title":"Frontiers in neuroscience"},{"key":"pone.0224744.ref018","article-title":"The Energy Landscape of Neurophysiological Activity Implicit in Brain Network Structure","volume":"8","author":"S Gu","year":"2018","journal-title":"Sci Rep-Uk"},{"issue":"Pt B","key":"pone.0224744.ref019","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.neuroimage.2018.01.041","article-title":"Co-activation patterns in resting-state fMRI signals","volume":"180","author":"X Liu","year":"2018","journal-title":"Neuroimage"},{"key":"pone.0224744.ref020","doi-asserted-by":"crossref","unstructured":"Wohlberg B. Efficient Convolutional Sparse Coding. 2014 Ieee International Conference on Acoustics, Speech and Signal Processing (Icassp). 2014. WOS:000343655307042.","DOI":"10.1109\/ICASSP.2014.6854992"},{"key":"pone.0224744.ref021","article-title":"The Positive and Negative Syndrome Scale (PANSS): rationale and standardisation","author":"SR Kay","year":"1989","journal-title":"The British Journal of Psychiatry"},{"key":"pone.0224744.ref022","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.nicl.2014.07.003","article-title":"Dynamic functional connectivity analysis reveals transient states of dysconnectivity in schizophrenia","volume":"5","author":"E Damaraju","year":"2014","journal-title":"NeuroImage: Clinical"},{"issue":"3","key":"pone.0224744.ref023","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0149849","article-title":"Higher Dimensional Meta-State Analysis Reveals Reduced Resting fMRI Connectivity Dynamism in Schizophrenia Patients","volume":"11","author":"RL Miller","year":"2016","journal-title":"Plos One"},{"issue":"6790","key":"pone.0224744.ref024","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1038\/35016590","article-title":"The temporal response of the brain after eating revealed by functional MRI","volume":"405","author":"Y Liu","year":"2000","journal-title":"Nature"},{"issue":"1","key":"pone.0224744.ref025","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/hbm.20362","article-title":"Development of 2dTCA for the detection of irregular, transient BOLD activity","volume":"29","author":"VL Morgan","year":"2008","journal-title":"Human brain mapping"},{"issue":"12","key":"pone.0224744.ref026","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1016\/j.biopsych.2015.02.005","article-title":"Brain rhythms connect impaired inhibition to altered cognition in schizophrenia","volume":"77","author":"BR Pittman-Polletta","year":"2015","journal-title":"Biol Psychiatry"},{"key":"pone.0224744.ref027","article-title":"Oscillatory, Computational, and Behavioral Evidence for Impaired GABAergic Inhibition in Schizophrenia","author":"AD Shaw","year":"2019","journal-title":"Schizophr Bull"},{"issue":"7","key":"pone.0224744.ref028","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1586\/14737175.2013.811899","article-title":"Functional dysconnectivity in schizophrenia and its relationship to neural synchrony","volume":"13","author":"AM Brennan","year":"2013","journal-title":"Expert Rev Neurother"},{"issue":"5","key":"pone.0224744.ref029","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.neubiorev.2010.11.004","article-title":"Dysconnectivity in schizophrenia: where are we now?","volume":"35","author":"W Pettersson-Yeo","year":"2011","journal-title":"Neurosci Biobehav Rev"},{"issue":"2","key":"pone.0224744.ref030","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.conb.2012.11.004","article-title":"Dysconnectivity, large-scale networks and neuronal dynamics in schizophrenia","volume":"23","author":"PJ Uhlhaas","year":"2013","journal-title":"Curr Opin Neurobiol"},{"issue":"5","key":"pone.0224744.ref031","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1037\/abn0000442","article-title":"Failures in Top-Down Control in Schizophrenia Revealed by Patterns of Saccadic Eye Movements","volume":"128","author":"S Bansal","year":"2019","journal-title":"J Abnorm Psychol"},{"issue":"3","key":"pone.0224744.ref032","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0022-3956(94)90009-4","article-title":"Is Schizophrenia Due to Excessive Synaptic Pruning in the Prefrontal Cortex\u2014the Feinberg Hypothesis Revisited","volume":"28","author":"MS Keshavan","year":"1994","journal-title":"J Psychiatr Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0224744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T02:14:07Z","timestamp":1665195247000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0224744"}},"subtitle":[],"editor":[{"given":"Xi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,12,11]]},"references-count":32,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,11]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0224744","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/543751","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,11]]}}}