{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:44:46Z","timestamp":1790747086011,"version":"4.1.0"},"reference-count":67,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T00:00:00Z","timestamp":1574121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0225032","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T18:29:16Z","timestamp":1574188156000},"page":"e0225032","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":30,"title":["Prosthetic push-off power in trans-tibial amputee level ground walking: A systematic review"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4688-1515","authenticated-orcid":true,"given":"Roy","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Tronicke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Abel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Lechler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,11,19]]},"reference":[{"issue":"3","key":"pone.0225032.ref001","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.apmr.2007.11.005","article-title":"Estimating the Prevalence of Limb Loss in the United States: 2005 to 2050","volume":"89","author":"K Ziegler-Graham","year":"2008","journal-title":"Arch Phys Med Rehabil"},{"issue":"23","key":"pone.0225032.ref002","doi-asserted-by":"crossref","first-page":"3676","DOI":"10.1242\/jeb.140376","article-title":"A unified perspective on ankle push-off in human walking","volume":"219","author":"KE Zelik","year":"2016","journal-title":"J Exp Biol"},{"issue":"6","key":"pone.0225032.ref003","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1093\/ptj\/70.6.340","article-title":"Biomechanical walking pattern changes in the fit and healthy elderly","volume":"70","author":"DA Winter","year":"1990","journal-title":"Phys Ther"},{"issue":"14","key":"pone.0225032.ref004","doi-asserted-by":"crossref","first-page":"3397","DOI":"10.1016\/j.jbiomech.2016.09.010","article-title":"Whole-body angular momentum during sloped walking using passive and powered lower-limb prostheses","volume":"49","author":"NT Pickle","year":"2016","journal-title":"J Biomech"},{"issue":"2","key":"pone.0225032.ref005","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.gaitpost.2007.12.002","article-title":"Balance control on a moving platform in unilateral lower limb amputees","volume":"28","author":"AH Vrieling","year":"2008","journal-title":"Gait Posture"},{"key":"pone.0225032.ref006","doi-asserted-by":"crossref","DOI":"10.1002\/9780470549148","volume-title":"Biomechanics and motor control of human movement","author":"DA Winter","year":"2009"},{"issue":"5","key":"pone.0225032.ref007","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1109\/TNSRE.2014.2356722","article-title":"Mechanisms of Gait Asymmetry Due to Push-Off Deficiency in Unilateral Amputees","volume":"23","author":"PG Adamczyk","year":"2015","journal-title":"IEEE Trans Neural Syst Rehabil Eng"},{"issue":"2","key":"pone.0225032.ref008","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3109\/03093649409164389","article-title":"Energy expenditure of trans-tibial amputees during ambulation at self-selected pace","volume":"18","author":"RS Gailey","year":"1994","journal-title":"Prosthet Orthot Int"},{"issue":"1","key":"pone.0225032.ref009","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.gaitpost.2009.02.009","article-title":"The energy cost for the step-to-step transition in amputee walking","volume":"30","author":"H Houdijk","year":"2009","journal-title":"Gait Posture"},{"issue":"4","key":"pone.0225032.ref010","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.gaitpost.2011.07.001","article-title":"The Effect of Prosthetic Foot Push-off on Mechanical Loading Associated with Knee Osteoarthritis in Lower Extremity Amputees","volume":"34","author":"DC Morgenroth","year":"2011","journal-title":"Gait Posture"},{"issue":"10","key":"pone.0225032.ref011","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.clinbiomech.2014.09.005","article-title":"Biomechanical risk factors for knee osteoarthritis when using passive and powered ankle\u2013foot prostheses","volume":"29","author":"ER Esposito","year":"2014","journal-title":"Clin Biomech"},{"issue":"5","key":"pone.0225032.ref012","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.pmrj.2012.01.003","article-title":"Osteoarthritis in the disabled population: a mechanical perspective","volume":"4","author":"DC Morgenroth","year":"2012","journal-title":"PM&R"},{"issue":"1","key":"pone.0225032.ref013","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0021-9290(91)90327-J","article-title":"Joint moment and muscle power output characteristics of below knee amputees during running: the influence of energy storing prosthetic feet","volume":"24","author":"JM Czerniecki","year":"1991","journal-title":"J Biomech"},{"key":"pone.0225032.ref014","first-page":"800","article-title":"Controlled energy storage and return prosthesis reduces metabolic cost of walking","volume":"600","author":"SH Collins","year":"2005","journal-title":"Power"},{"key":"pone.0225032.ref015","volume":"7","author":"RD Snyder","year":"1995","journal-title":"The effect of five prosthetic feet on the gait and loading of the sound limb in dysvascular below-knee amputees"},{"issue":"11","key":"pone.0225032.ref016","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1016\/j.apmr.2012.06.009","article-title":"Evaluation of a Powered Ankle-Foot Prosthetic System During Walking","volume":"93","author":"AE Ferris","year":"2012","journal-title":"Arch Phys Med Rehabil"},{"issue":"3","key":"pone.0225032.ref017","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1177\/0309364614564021","article-title":"Step-to-step transition work during level and inclined walking using passive and powered ankle\u2013foot prostheses","volume":"40","author":"ER Esposito","year":"2016","journal-title":"Prosthet Orthot Int"},{"issue":"9","key":"pone.0225032.ref018","doi-asserted-by":"crossref","first-page":"S207","DOI":"10.1016\/j.pmrj.2018.06.015","article-title":"Motorized Biomechatronic Upper and Lower Limb Prostheses\u2014Clinically Relevant Outcomes","volume":"10","author":"K Lechler","year":"2018","journal-title":"PM&R"},{"issue":"1728","key":"pone.0225032.ref019","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1098\/rspb.2011.1194","article-title":"Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation","volume":"279","author":"HM Herr","year":"2012","journal-title":"Proc Biol Sci"},{"issue":"14","key":"pone.0225032.ref020","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1016\/j.jbiomech.2016.09.015","article-title":"Increasing ankle push-off work with a powered prosthesis does not necessarily reduce metabolic rate for transtibial amputees","volume":"49","author":"RE Quesada","year":"2016","journal-title":"J Biomech"},{"key":"pone.0225032.ref021","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-94-017-8932-5_5","volume-title":"Neuro-Robotics","author":"M Grimmer","year":"2014"},{"key":"pone.0225032.ref022","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3389\/frobt.2018.00036","article-title":"Case Study: A Bio-Inspired Control Algorithm for a Robotic Foot-Ankle Prosthesis Provides Adaptive Control of Level Walking and Stair Ascent","volume":"5","author":"U Tahir","year":"2018","journal-title":"Front Robot AI"},{"key":"pone.0225032.ref023","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1743-0003-10-49","article-title":"Effects of a powered ankle-foot prosthesis on kinetic loading of the unaffected leg during level-ground walking","volume":"10","author":"AM Grabowski","year":"2013","journal-title":"J NeuroEngineering RehabilJun 7"},{"issue":"6","key":"pone.0225032.ref024","doi-asserted-by":"crossref","first-page":"2512","DOI":"10.1109\/TMECH.2017.2766205","article-title":"Combining push-off power and nonlinear damping behaviors for a lightweight motor-driven transtibial prosthesis","volume":"22","author":"Y Feng","year":"2017","journal-title":"IEEEASME Trans Mechatron"},{"issue":"1","key":"pone.0225032.ref025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"D Moher","year":"2015","journal-title":"Syst Rev"},{"key":"pone.0225032.ref026","article-title":"Advances in Propulsive Bionic Feet and Their Actuation Principles","author":"P Cherelle","year":"2014","journal-title":"Adv Mech Eng Lond"},{"issue":"12","key":"pone.0225032.ref027","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/0003-9993(93)90095-R","article-title":"Comparison of gait between young adults fitted with the space foot and nondisabled persons","volume":"74","author":"F Prince","year":"1993","journal-title":"Arch Phys Med Rehabil"},{"issue":"1","key":"pone.0225032.ref028","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/BF02522937","article-title":"Modelling and gait evaluation of asymmetrical-keel foot prosthesis","volume":"33","author":"P Allard","year":"1995","journal-title":"Med Biol Eng Comput"},{"issue":"4","key":"pone.0225032.ref029","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1109\/TNSRE.2011.2159018","article-title":"Systematic variation of prosthetic foot spring affects center-of-mass mechanics and metabolic cost during walking","volume":"19","author":"KE Zelik","year":"2011","journal-title":"IEEE Trans Neural Syst Rehabil Eng Publ IEEE Eng Med Biol Soc"},{"issue":"4","key":"pone.0225032.ref030","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1177\/0309364612461521","article-title":"Effects of heel lifting on transtibial amputee gait before and after treadmill walking: a case study","volume":"37","author":"LF Yeung","year":"2013","journal-title":"Prosthet Orthot Int"},{"issue":"3","key":"pone.0225032.ref031","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.gaitpost.2011.05.014","article-title":"Compensatory mechanisms of transtibial amputees during circular turning","volume":"34","author":"JD Ventura","year":"2011","journal-title":"Gait Posture"},{"key":"pone.0225032.ref032","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.gaitpost.2018.06.022","article-title":"Benefits of an increased prosthetic ankle range of motion for individuals with a trans-tibial amputation walking with a new prosthetic foot","volume":"64","author":"DW Heitzmann","year":"2018","journal-title":"Gait Posture"},{"key":"pone.0225032.ref033","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.medengphy.2016.10.005","article-title":"Energy flow analysis of amputee walking shows a proximally-directed transfer of energy in intact limbs, compared to a distally-directed transfer in prosthetic limbs at push-off","volume":"39","author":"RA Weinert-Aplin","year":"2017","journal-title":"Med Eng Phys"},{"key":"pone.0225032.ref034","first-page":"1118","article-title":"Feasibility study of transtibial amputee walking using a powered prosthetic foot","volume":"2017","author":"M Grimmer","year":"2017","journal-title":"IEEE Int Conf Rehabil Robot Proc"},{"issue":"2","key":"pone.0225032.ref035","doi-asserted-by":"crossref","first-page":"024501","DOI":"10.1115\/1.4026633","article-title":"An Experimental Powered Lower Limb Prosthesis Using Proportional Myoelectric Control","volume":"8","author":"S Huang","year":"2014","journal-title":"J Med Devices"},{"issue":"8","key":"pone.0225032.ref036","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.mechatronics.2014.06.005","article-title":"Effects of toe stiffness on ankle kinetics in a robotic transtibial prosthesis during level-ground walking","volume":"24","author":"J Zhu","year":"2014","journal-title":"Mechatronics"},{"key":"pone.0225032.ref037","doi-asserted-by":"crossref","unstructured":"Realmuto J, Klute G, Devasia S. Preliminary Investigation of Symmetry Learning Control for Powered Ankle-Foot Prostheses. In: 2019 Wearable Robotics Association Conference (WearRAcon) [Internet]. Scottsdale, AZ, USA: IEEE; 2019 [cited 2019 Jul 4]. p. 40\u20135. Available from: https:\/\/ieeexplore.ieee.org\/document\/8719630\/","DOI":"10.1109\/WEARRACON.2019.8719630"},{"issue":"1","key":"pone.0225032.ref038","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s12984-018-0347-1","article-title":"Prosthetic energy return during walking increases after 3 weeks of adaptation to a new device","volume":"15","author":"SF Ray","year":"2018","journal-title":"J Neuroengineering Rehabil"},{"issue":"1","key":"pone.0225032.ref039","doi-asserted-by":"crossref","first-page":"5354","DOI":"10.1038\/s41598-018-23705-8","article-title":"Increasing prosthetic foot energy return affects whole-body mechanics during walking on level ground and slopes","volume":"8","author":"WL Childers","year":"2018","journal-title":"Sci Rep"},{"key":"pone.0225032.ref040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jbiomech.2018.04.017","article-title":"Ankle and foot power in gait analysis: Implications for science, technology and clinical assessment","volume":"75","author":"KE Zelik","year":"2018","journal-title":"J Biomech"},{"issue":"5","key":"pone.0225032.ref041","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1109\/TNSRE.2015.2441061","article-title":"Locomotor Adaptation by Transtibial Amputees Walking With an Experimental Powered Prosthesis Under Continuous Myoelectric Control","volume":"24","author":"S Huang","year":"2016","journal-title":"IEEE Trans Neural Syst Rehabil Eng Publ IEEE Eng Med Biol Soc"},{"issue":"2","key":"pone.0225032.ref042","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.clinbiomech.2013.11.019","article-title":"Changes to level ground transtibial amputee gait with a weighted backpack","volume":"29","author":"SS Doyle","year":"2014","journal-title":"Clin Biomech"},{"issue":"3","key":"pone.0225032.ref043","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3109\/03093649409164399","article-title":"Benchmark data for elderly, vascular trans-tibial amputees after rehabilitation","volume":"18","author":"WA Hubbard","year":"1994","journal-title":"Prosthet Orthot Int"},{"issue":"1","key":"pone.0225032.ref044","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12984-018-0404-9","article-title":"Energy storing and return prosthetic feet improve step length symmetry while preserving margins of stability in persons with transtibial amputation","volume":"15","author":"H Houdijk","year":"2018","journal-title":"J Neuroengineering Rehabil"},{"issue":"1","key":"pone.0225032.ref045","first-page":"CD003978","article-title":"Prescription of prosthetic ankle-foot mechanisms after lower limb amputation","author":"C Hofstad","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"pone.0225032.ref046","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.humov.2011.08.005","article-title":"The effects of a controlled energy storage and return prototype prosthetic foot on transtibial amputee ambulation","volume":"31","author":"AD Segal","year":"2012","journal-title":"Hum Mov Sci"},{"issue":"10","key":"pone.0225032.ref047","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1682\/JRRD.2014.03.0081","article-title":"Differentiation between solid-ankle cushioned heel and energy storage and return prosthetic foot based on step-to-step transition cost","volume":"51","author":"D Wezenberg","year":"2014","journal-title":"J Rehabil Res Dev"},{"key":"pone.0225032.ref048","first-page":"6650375","article-title":"Effects of a powered ankle-foot prosthesis on kinetic loading of the contralateral limb: a case series","volume":"2013","author":"D Hill","year":"2013","journal-title":"IEEE Int Conf Rehabil Robot Proc"},{"issue":"4","key":"pone.0225032.ref049","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1109\/86.340873","article-title":"A new technique for the calculation of the energy stored, dissipated, and recovered in different ankle-foot prostheses","volume":"2","author":"F Prince","year":"1994","journal-title":"IEEE Trans Rehabil Eng"},{"issue":"15","key":"pone.0225032.ref050","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1016\/j.jbiomech.2012.08.017","article-title":"segment model for quantifying total power of anatomical and prosthetic below-knee structures during stance in gait","volume":"45","author":"KZ Takahashi","year":"2012","journal-title":"J Biomech"},{"issue":"2","key":"pone.0225032.ref051","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1177\/0309364617706749","article-title":"The effects of common footwear on stance-phase mechanical properties of the prosthetic foot-shoe system","volume":"42","author":"MJ Major","year":"2018","journal-title":"Prosthet Orthot Int"},{"issue":"2","key":"pone.0225032.ref052","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.gaitpost.2003.09.011","article-title":"Measurement and management of errors in quantitative gait data","volume":"20","author":"MH Schwartz","year":"2004","journal-title":"Gait Posture"},{"issue":"8","key":"pone.0225032.ref053","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1053\/apmr.2001.24295","article-title":"The prevalence and risk factors of falling and fear of falling among lower extremity amputees","volume":"82","author":"WC Miller","year":"2001","journal-title":"Arch Phys Med Rehabil"},{"issue":"4","key":"pone.0225032.ref054","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.apmr.2004.09.003","article-title":"Dermatologic conditions associated with use of a lower-extremity prosthesis","volume":"86","author":"NL Dudek","year":"2005","journal-title":"Arch Phys Med Rehabil"},{"issue":"1","key":"pone.0225032.ref055","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1191\/0269215505cr819oa","article-title":"Chronic low back pain in traumatic lower limb amputees","volume":"19","author":"J Kulkarni","year":"2005","journal-title":"Clin Rehabil"},{"issue":"3","key":"pone.0225032.ref056","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.apmr.2008.08.220","article-title":"The prevalence of osteoarthritis of the intact hip and knee among traumatic leg amputees","volume":"90","author":"PA Struyf","year":"2009","journal-title":"Arch Phys Med Rehabil"},{"issue":"145","key":"pone.0225032.ref057","doi-asserted-by":"crossref","first-page":"20180442","DOI":"10.1098\/rsif.2018.0442","article-title":"Use of a powered ankle\u2013foot prosthesis reduces the metabolic cost of uphill walking and improves leg work symmetry in people with transtibial amputations","volume":"15","author":"JR Montgomery","year":"2018","journal-title":"J R Soc Interface"},{"issue":"7","key":"pone.0225032.ref058","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1053\/joca.2002.0797","article-title":"Increased knee joint loads during walking are present in subjects with knee osteoarthritis","volume":"10","author":"AJ Baliunas","year":"2002","journal-title":"Osteoarthritis Cartilage"},{"issue":"9","key":"pone.0225032.ref059","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1002\/art.21262","article-title":"Secondary gait changes in patients with medial compartment knee osteoarthritis: Increased load at the ankle, knee, and hip during walking","volume":"52","author":"A M\u00fcndermann","year":"2005","journal-title":"Arthritis Rheum"},{"key":"pone.0225032.ref060","first-page":"3020","article-title":"Powered ankle-foot prosthesis for the improvement of amputee ambulation","volume":"2007","author":"SK Au","year":"2007","journal-title":"Conf Proc Annu Int Conf IEEE Eng Med Biol Soc IEEE Eng Med Biol Soc Annu Conf"},{"key":"pone.0225032.ref061","first-page":"8255","article-title":"Comparing a passive-elastic and a powered prosthesis in transtibial amputees","volume":"2011","author":"C Mancinelli","year":"2011","journal-title":"Conf Proc Annu Int Conf IEEE Eng Med Biol Soc IEEE Eng Med Biol Soc Annu Conf"},{"key":"pone.0225032.ref062","doi-asserted-by":"crossref","DOI":"10.1038\/srep07213","article-title":"Prosthetic ankle push-off work reduces metabolic rate but not collision work in non-amputee walking","volume":"4","author":"JM Caputo","year":"2014","journal-title":"Sci Rep"},{"key":"pone.0225032.ref063","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.jbiomech.2019.07.029","article-title":"Reactive gait and postural adjustments following the first exposures to (un) expected stepdown","volume":"94","author":"S. AminiAghdam","year":"2019","journal-title":"Journal of biomechanics"},{"key":"pone.0225032.ref064","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3389\/frobt.2017.00072","article-title":"Individual leg and joint work during sloped walking for people with a transtibial amputation using passive and powered prostheses","volume":"4","author":"JR Jeffers","year":"2017","journal-title":"Front Robot AI"},{"issue":"13","key":"pone.0225032.ref065","doi-asserted-by":"crossref","first-page":"3380","DOI":"10.1016\/j.jbiomech.2014.08.001","article-title":"Whole-body angular momentum during stair walking using passive and powered lower-limb prostheses","volume":"47","author":"NT Pickle","year":"2014","journal-title":"J Biomech"},{"key":"pone.0225032.ref066","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/1743-0003-10-107","article-title":"Walking speed related joint kinetic alterations in trans-tibial amputees: impact of hydraulic 'ankle\u2019 damping","volume":"10","author":"AR De Asha","year":"2013","journal-title":"J NeuroEngineering Rehabil"},{"issue":"2","key":"pone.0225032.ref067","first-page":"177","article-title":"Mechanical efficiency during gait of adults with transtibial amputation: a pilot study comparing the SACH, Seattle, and Golden-Ankle prosthetic feet","volume":"35","author":"F Prince","year":"1998","journal-title":"J Rehabil Res Dev"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0225032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T03:55:04Z","timestamp":1695441304000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0225032"}},"subtitle":[],"editor":[{"given":"Arezoo","family":"Eshraghi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,11,19]]},"references-count":67,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019,11,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0225032","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,19]]}}}