{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:56:24Z","timestamp":1774536984160,"version":"3.50.1"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T00:00:00Z","timestamp":1574121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0225403","type":"journal-article","created":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T13:28:25Z","timestamp":1574170105000},"page":"e0225403","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["Prognostic value of the model for end-stage liver disease excluding INR score (MELD-XI) in patients with adult congenital heart disease"],"prefix":"10.1371","volume":"14","author":[{"given":"Ryo","family":"Konno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Tatebe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichiro","family":"Sugimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimio","family":"Satoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanobu","family":"Miura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saori","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruka","family":"Sato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yosuke","family":"Terui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Miyata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikatsu","family":"Saiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7534-4826","authenticated-orcid":true,"given":"Hiroaki","family":"Shimokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,11,19]]},"reference":[{"issue":"22","key":"pone.0225403.ref001","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1161\/CIRCULATIONAHA.110.946343","article-title":"Temporal trends in survival to adulthood among patients born with congenital heart disease from 1970 to 1992 in Belgium","volume":"122","author":"P Moons","year":"2010","journal-title":"Circulation"},{"issue":"12","key":"pone.0225403.ref002","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s12471-012-0335-1","article-title":"Epidemiology of adult congenital heart disease: demographic variations worldwide","volume":"20","author":"BJM Mulder","year":"2012","journal-title":"Neth Heart J"},{"issue":"10","key":"pone.0225403.ref003","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1093\/eurheartj\/ehq032","article-title":"Mortality in adult congenital heart disease","volume":"31","author":"CL Verheugt","year":"2010","journal-title":"Eur Heart J"},{"issue":"22","key":"pone.0225403.ref004","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1161\/CIRCULATIONAHA.115.017202","article-title":"Survival Prospects and Circumstances of Death in Contemporary Adult Congenital Heart Disease Patients Under Follow-Up at a Large Tertiary Centre","volume":"132","author":"GP Diller","year":"2015","journal-title":"Circulation"},{"key":"pone.0225403.ref005","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijcard.2016.02.133","article-title":"Cause of death in adults with congenital heart disease\u2014An analysis of the German National Register for Congenital Heart Defects","volume":"211","author":"CC Engelings","year":"2016","journal-title":"Int J Cardiol"},{"key":"pone.0225403.ref006","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ijcard.2017.05.132","article-title":"Mortality in adults with congenital heart disease","volume":"245","author":"P Naidu","year":"2017","journal-title":"Int J Cardiol"},{"issue":"11","key":"pone.0225403.ref007","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/j.amjcard.2018.08.045","article-title":"Effects of Hepatitis C Virus Antibody-Positivity on Cardiac Function and Long-Term Prognosis in Patients With Adult Congenital Heart Disease","volume":"122","author":"R Konno","year":"2018","journal-title":"Am J Cardiol"},{"issue":"4","key":"pone.0225403.ref008","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1053\/he.2000.5852","article-title":"A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts","volume":"31","author":"M Malinchoc","year":"2000","journal-title":"Hepatology"},{"issue":"2","key":"pone.0225403.ref009","doi-asserted-by":"crossref","first-page":"178","DOI":"10.5114\/kitp.2014.43847","article-title":"The Model for End-Stage Liver Disease (MELD) can predict outcomes in ambulatory patients with advanced heart failure who have been referred for cardiac transplantation evaluation","volume":"11","author":"B Szygula-Jurkiewicz","year":"2014","journal-title":"Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery"},{"issue":"1","key":"pone.0225403.ref010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/lt.20906","article-title":"MELD-XI: a rational approach to \"sickest first\" liver transplantation in cirrhotic patients requiring anticoagulant therapy","volume":"13","author":"DM Heuman","year":"2007","journal-title":"Liver Transpl"},{"issue":"6","key":"pone.0225403.ref011","doi-asserted-by":"crossref","first-page":"e100618","DOI":"10.1371\/journal.pone.0100618","article-title":"Liver dysfunction assessed by model for end-stage liver disease excluding INR (MELD-XI) scoring system predicts adverse prognosis in heart failure","volume":"9","author":"S Abe","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"pone.0225403.ref012","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.ijcard.2014.08.052","article-title":"Prognostic impact of renal and hepatic dysfunction based on the MELD-XI score in patients with acute heart failure","volume":"176","author":"T Inohara","year":"2014","journal-title":"Int J Cardiol"},{"issue":"12","key":"pone.0225403.ref013","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1002\/ejhf.644","article-title":"Impaired hepato-renal function defined by the MELD XI score as prognosticator in acute heart failure","volume":"18","author":"J Biegus","year":"2016","journal-title":"Eur J Heart Fail"},{"issue":"6","key":"pone.0225403.ref014","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1053\/j.ajkd.2008.12.034","article-title":"Revised equations for estimated GFR from serum creatinine in Japan","volume":"53","author":"S Matsuo","year":"2009","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"pone.0225403.ref015","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/S0735-1097(01)01272-4","article-title":"Task force 1: the changing profile of congenital heart disease in adult life","volume":"37","author":"CA Warnes","year":"2001","journal-title":"J Am Coll Cardiol"},{"issue":"3","key":"pone.0225403.ref016","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1207\/S15324796ABM2603_02","article-title":"Classification and regression tree analysis in public health: methodological review and comparison with logistic regression","volume":"26","author":"SC Lemon","year":"2003","journal-title":"Ann Behav Med"},{"issue":"2","key":"pone.0225403.ref017","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s10741-012-9370-7","article-title":"Co-morbidities in heart failure","volume":"19","author":"VM van Deursen","year":"2014","journal-title":"Heart Fail Rev"},{"issue":"2","key":"pone.0225403.ref018","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/eurjhf\/hfn031","article-title":"Liver function abnormalities and outcome in patients with chronic heart failure: data from the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program","volume":"11","author":"LA Allen","year":"2009","journal-title":"Eur J Heart Fail"},{"issue":"2","key":"pone.0225403.ref019","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1161\/01.CIR.102.2.203","article-title":"Renal function, neurohormonal activation, and survival in patients with chronic heart failure","volume":"102","author":"HL Hillege","year":"2000","journal-title":"Circulation"},{"issue":"4","key":"pone.0225403.ref020","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1007\/s00134-007-0544-z","article-title":"Adult congenital heart disease: intensive care management and outcome prediction","volume":"33","author":"S Price","year":"2007","journal-title":"Intensive Care Med"},{"issue":"18","key":"pone.0225403.ref021","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1161\/CIRCULATIONAHA.107.734921","article-title":"Prevalence, predictors, and prognostic value of renal dysfunction in adults with congenital heart disease","volume":"117","author":"K Dimopoulos","year":"2008","journal-title":"Circulation"},{"issue":"2","key":"pone.0225403.ref022","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1161\/CIRCULATIONAHA.108.838656","article-title":"Model for end-stage liver disease score predicts left ventricular assist device operative transfusion requirements, morbidity, and mortality","volume":"121","author":"JC Matthews","year":"2010","journal-title":"Circulation"},{"issue":"6","key":"pone.0225403.ref023","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.healun.2012.02.008","article-title":"Hepatic dysfunction and survival after orthotopic heart transplantation: application of the MELD scoring system for outcome prediction","volume":"31","author":"A Chokshi","year":"2012","journal-title":"J Heart Lung Transplant"},{"issue":"22","key":"pone.0225403.ref024","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/j.jacc.2012.12.056","article-title":"Hepatic dysfunction in ambulatory patients with heart failure: application of the MELD scoring system for outcome prediction","volume":"61","author":"MS Kim","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"pone.0225403.ref025","first-page":"1087","article-title":"Vitamin K antagonists in heart disease: current status and perspectives (Section III). Position paper of the ESC Working Group on Thrombosis\u2014Task Force on Anticoagulants in Heart Disease","volume":"110","author":"R De Caterina","year":"2013","journal-title":"Thromb Haemost"},{"issue":"12","key":"pone.0225403.ref026","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1016\/j.cjca.2017.08.009","article-title":"Anticoagulation for Thromboembolic Risk Reduction in Adults With Congenital Heart Disease","volume":"33","author":"D Wan","year":"2017","journal-title":"Can J Cardiol"},{"issue":"7","key":"pone.0225403.ref027","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1136\/heartjnl-2012-303347","article-title":"MELD-XI score and cardiac mortality or transplantation in patients after Fontan surgery","volume":"99","author":"GE Assenza","year":"2013","journal-title":"Heart"},{"issue":"7","key":"pone.0225403.ref028","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.cardfail.2015.09.002","article-title":"Outcomes of Adult Patients With Congenital Heart Disease After Heart Transplantation: Impact of Disease Type, Previous Thoracic Surgeries, and Bystander Organ Dysfunction","volume":"22","author":"M Lewis","year":"2016","journal-title":"J Card Fail"},{"issue":"6","key":"pone.0225403.ref029","doi-asserted-by":"crossref","first-page":"e13257","DOI":"10.1111\/ctr.13257","article-title":"Prognostic utility of MELD-XI in adult congenital heart disease patients undergoing cardiac transplantation","volume":"32","author":"ED Adams","year":"2018","journal-title":"Clin Transplant"},{"issue":"10","key":"pone.0225403.ref030","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1016\/j.jacc.2005.12.065","article-title":"Clinical outcome of 193 extracardiac Fontan patients: the first 15 years","volume":"47","author":"S Giannico","year":"2006","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"pone.0225403.ref031","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1161\/CIRCULATIONAHA.107.738559","article-title":"Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery","volume":"117","author":"P Khairy","year":"2008","journal-title":"Circulation"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0225403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,19]],"date-time":"2019-11-19T13:28:46Z","timestamp":1574170126000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0225403"}},"subtitle":[],"editor":[{"given":"Maria Lucia","family":"Narducci","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,11,19]]},"references-count":31,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019,11,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0225403","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,19]]}}}