{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:03:42Z","timestamp":1740146622701,"version":"3.37.3"},"reference-count":48,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T00:00:00Z","timestamp":1576627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0226614","type":"journal-article","created":{"date-parts":[[2019,12,18]],"date-time":"2019-12-18T18:34:08Z","timestamp":1576694048000},"page":"e0226614","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Syphilis among adult males with a history of male-to-male sexual contact living with diagnosed HIV in New York State (excluding New York City): The challenge of intersecting epidemics"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8114-7626","authenticated-orcid":true,"given":"Rachel","family":"Hart-Malloy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Patterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2404-4038","authenticated-orcid":true,"given":"Salvatore","family":"Currenti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis","family":"O\u2019Donnell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayleen KL","family":"Gunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2019,12,18]]},"reference":[{"key":"pone.0226614.ref001","unstructured":"Centers for Disease Control and Prevention. HIV Surveillance Report, 2017. November 2018."},{"issue":"4","key":"pone.0226614.ref002","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.annepidem.2017.02.003","article-title":"Lifetime risk of a diagnosis of HIV infection in the United States","volume":"27","author":"KL Hess","year":"2017","journal-title":"Annals of epidemiology"},{"journal-title":"Estimated HIV incidence and prevalence in the United States, 2010\u20132015","year":"2018","author":"Centers for Disease Control and Prevention","key":"pone.0226614.ref003"},{"journal-title":"New York State HIV\/AIDS Annual Surveillance Report for Cases Diagnosed through December 2016","year":"2017","author":"Bureau of HIV\/AIDS Epidemiology AIDS Institute New York State Department of Health","key":"pone.0226614.ref004"},{"journal-title":"Sexually Transmitted Disease Surveillance 2017","year":"2018","author":"Division of STD Prevention National Center for HIV\/AIDS Viral Hepatitis STD and TB Prevention Centers for Disease Control and Prevention","key":"pone.0226614.ref005"},{"issue":"18","key":"pone.0226614.ref006","first-page":"402","article-title":"Prevention. Primary and secondary syphilis\u2014United States, 2005\u20132013","volume":"63","author":"ME Patton","year":"2014","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"13","key":"pone.0226614.ref007","doi-asserted-by":"crossref","first-page":"349","DOI":"10.15585\/mmwr.mm6613a1","article-title":"State-Specific Rates of Primary and Secondary Syphilis Among Men Who Have Sex with Men\u2014United States, 2015","volume":"66","author":"A de Voux","year":"2017","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"3","key":"pone.0226614.ref008","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1097\/QAI.0000000000001508","article-title":"Rates of Primary and Secondary Syphilis Among White and Black Non-Hispanic Men Who Have Sex With Men, United States, 2014","volume":"76","author":"JA Grey","year":"2017","journal-title":"J Acquir Immune Defic Syndr"},{"journal-title":"STI surveillance and partner services data (unpublished data)","year":"2018","author":"New York State Department of Health","key":"pone.0226614.ref009"},{"key":"pone.0226614.ref010","first-page":"5","article-title":"Sexually Transmitted Infections Among HIV-Infected Individuals in the District of Columbia and Estimated HIV Transmission Risk: Data From the DC Cohort","author":"J Lucar","year":"2018","journal-title":"Open Forum Infect Dis"},{"issue":"3","key":"pone.0226614.ref011","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1136\/sti.2010.047514","article-title":"Prevalence of sexually transmitted co-infections in people living with HIV\/AIDS: systematic review with implications for using HIV treatments for prevention","volume":"87","author":"SC Kalichman","year":"2011","journal-title":"Sex Transm Infect"},{"issue":"7","key":"pone.0226614.ref012","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1093\/cid\/ciu450","article-title":"Syphilis predicts HIV incidence among men and transgender women who have sex with men in a preexposure prophylaxis trial","volume":"59","author":"MM Solomon","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"RR-4","key":"pone.0226614.ref013","first-page":"1","article-title":"Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America","volume":"58","author":"JE Kaplan","year":"2009","journal-title":"MMWR Recomm Rep"},{"issue":"7","key":"pone.0226614.ref014","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S1473-3099(04)01061-8","article-title":"Syphilis and HIV: a dangerous combination","volume":"4","author":"WA Lynn","year":"2004","journal-title":"Lancet Infect Dis"},{"key":"pone.0226614.ref015","article-title":"Syphilis testing among sexually active men who have sex with men and who are receiving medical care for HIV in the United States-Medical Monitoring Project, 2013\u20132014","author":"A de Voux","year":"2018","journal-title":"Clin Infect Dis"},{"issue":"3","key":"pone.0226614.ref016","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/j.1600-0897.2010.00942.x","article-title":"Interactions of HIV, other sexually transmitted diseases, and genital tract inflammation facilitating local pathogen transmission and acquisition","volume":"65","author":"KH Mayer","year":"2011","journal-title":"Am J Reprod Immunol"},{"issue":"4","key":"pone.0226614.ref017","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/COH.0b013e32833a8844","article-title":"Contribution of sexually transmitted infections to the sexual transmission of HIV","volume":"5","author":"H Ward","year":"2010","journal-title":"Curr Opin HIV AIDS"},{"issue":"Suppl 3","key":"pone.0226614.ref018","doi-asserted-by":"crossref","first-page":"S363","DOI":"10.1097\/QAI.0000000000001412","article-title":"Syphilis Screening and Diagnosis Among Men Who Have Sex With Men, 2008\u20132014, 20 U.S. Cities","volume":"75","author":"Q An","year":"2017","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"2","key":"pone.0226614.ref019","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/cid\/civ289","article-title":"The high risk of an HIV diagnosis following a diagnosis of syphilis: a population-level analysis of New York City men","volume":"61","author":"P Pathela","year":"2015","journal-title":"Clin Infect Dis"},{"key":"pone.0226614.ref020","unstructured":"Grey J, Torrone, E., Kidd, S., Bernstein, K., Weinstock, H., editor Estimated Primary & Secondary Syphilis Rates in MSM by HIV Status\u201434 States, 2014. 25th Conference on Retroviruses and Opportunistic Infections; 2018; Boston, MA."},{"issue":"2","key":"pone.0226614.ref021","doi-asserted-by":"crossref","first-page":"e5849","DOI":"10.1097\/MD.0000000000005849","article-title":"Factors associated with syphilis incidence in the HIV-infected in the era of highly active antiretrovirals","volume":"96","author":"M Shilaih","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"pone.0226614.ref022","unstructured":"Braunstein S, Pathela, P., Kersanske, L., editor Incidence of Sexually Transmitted Diseases Among Persons With HIV New York City 2000\u20132010. Conference on Retroviruses and Opportunistic Infections; 2014; Boston, MA."},{"issue":"1","key":"pone.0226614.ref023","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12879-018-3038-4","article-title":"Increasing incidence of syphilis among patients engaged in HIV care in Alberta, Canada: a retrospective clinic-based cohort study","volume":"18","author":"R Lang","year":"2018","journal-title":"BMC Infect Dis"},{"issue":"3","key":"pone.0226614.ref024","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/01.olq.0000187262.56820.c0","article-title":"Syphilis and human immunodeficiency virus (HIV)-1 coinfection: influence on CD4 T-cell count, HIV-1 viral load, and treatment response","volume":"33","author":"K Kofoed","year":"2006","journal-title":"Sex Transm Dis"},{"issue":"2","key":"pone.0226614.ref025","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/QAI.0000000000000730","article-title":"Viral Loads Among HIV-Infected Persons Diagnosed With Primary and Secondary Syphilis in 4 US Cities: New York City, Philadelphia, PA, Washington, DC, and Phoenix, AZ","volume":"70","author":"MM Taylor","year":"2015","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"16","key":"pone.0226614.ref026","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1001\/archinternmed.2012.2706","article-title":"Effect of early syphilis infection on plasma viral load and CD4 cell count in human immunodeficiency virus-infected men: results from the FHDH-ANRS CO4 cohort","volume":"172","author":"W Jarzebowski","year":"2012","journal-title":"Arch Intern Med"},{"issue":"15","key":"pone.0226614.ref027","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1097\/00002030-200410210-00012","article-title":"Syphilis increases HIV viral load and decreases CD4 cell counts in HIV-infected patients with new syphilis infections","volume":"18","author":"K Buchacz","year":"2004","journal-title":"AIDS"},{"key":"pone.0226614.ref028","unstructured":"New York State Department of Health Clinical Guidelines Program Sexually Transmitted Infections Guidelines Committee. Management of Syphilis in Patients with HIV 2018 [cited 2018]. Available from: https:\/\/www.hivguidelines.org\/sti-care\/syphilis\/#tab_6."},{"issue":"RR-03","key":"pone.0226614.ref029","first-page":"1","article-title":"Sexually transmitted diseases treatment guidelines, 2015","volume":"64","author":"Centers for Disease C, Prevention","year":"2015","journal-title":"MMWR Recomm Rep"},{"issue":"1","key":"pone.0226614.ref030","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/cit665","article-title":"Primary care guidelines for the management of persons infected with HIV: 2013 update by the HIV medicine association of the Infectious Diseases Society of America","volume":"58","author":"JA Aberg","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"21","key":"pone.0226614.ref031","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1001\/jama.2016.4114","article-title":"Screening for Syphilis: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force","volume":"315","author":"AG Cantor","year":"2016","journal-title":"JAMA"},{"issue":"21","key":"pone.0226614.ref032","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1001\/jama.2016.5824","article-title":"Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement","volume":"315","author":"Force USPST","year":"2016","journal-title":"JAMA"},{"issue":"9","key":"pone.0226614.ref033","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.4065\/82.9.1091","article-title":"Syphilis in the United States: an update for clinicians with an emphasis on HIV coinfection","volume":"82","author":"NM Zetola","year":"2007","journal-title":"Mayo Clin Proc"},{"volume-title":"Medicaid screening for syphilis among adult males living with HIV by region (unpublished data)","year":"2018","author":"New York State Department of Health","key":"pone.0226614.ref034"},{"key":"pone.0226614.ref035","unstructured":"Hart-Malloy R, Rosenthal, M., Patterson, W., Cukrovany, J., Currenti, S., Gunn, JLK, editor Syphilis diagnosis among men who have sex with men who are living with diagnosed HIV infection: Assessing morbidity in New York State (excluding New York City). STD Prevention Conference; 2018; Washington DC."},{"key":"pone.0226614.ref036","article-title":"Monitoring selected national HIV prevention and care objectives by using HIV surveillance data\u2014United States and 6 dependent areas, 2015","author":"Centers for Disease Control and Prevention","year":"2017","journal-title":"HIV Surveillance Supplemental Report"},{"key":"pone.0226614.ref037","unstructured":"HIV Reporting and Partner Notification Law Article 21 Title III. Sect. 2139 (1998)."},{"key":"pone.0226614.ref038","unstructured":"New York State Codes, Rules, and Regulations; Volume A-1a (Title 10) SubChapter G- AIDS Testing, Communicable Diseases and Poisoning; Part 63- HIV\/AIDS Testing, Reporting and Confidentiality of HIV-Related Information; Section 63.4: Filing of Reports, (05\/17\/2017, 2017)."},{"key":"pone.0226614.ref039","unstructured":"Centers for Disease Control and Prevention. National Notifiable Diseases Surveillance System (NNDSS), Surveillance Case Definitions, Syphilis (Treponema pallidum) [cited 2018]. Available from: https:\/\/wwwn.cdc.gov\/nndss\/conditions\/syphilis\/."},{"key":"pone.0226614.ref040","unstructured":"United States Census Bureau. American Community Survey, 2017 American Community Survey 5-Year Estimate [5\/14\/2018]. Available from: http:\/\/factfinder.census.gov\/."},{"key":"pone.0226614.ref041","unstructured":"Division of STD Prevention National Center for HIV\/AIDS Viral Hepatitis STD and TB Prevention Centers for Disease Control and Prevention. Syphilis\u2014CDC Fact Sheet (Detailed) 2017 [updated 11\/30\/2017; cited 2018]. Available from: https:\/\/www.cdc.gov\/std\/syphilis\/stdfact-syphilis-detailed.htm."},{"first-page":"2006","volume-title":"An Update and Review of the Diagnosis and Management of Syphilis","author":"T. Cherneskie","key":"pone.0226614.ref042"},{"issue":"Suppl 1","key":"pone.0226614.ref043","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1007\/s10461-013-0533-x","article-title":"Syphilis and HIV co-infection in patients who attend an AIDS outpatient clinic in Vitoria, Brazil","volume":"18","author":"FM Callegari","year":"2014","journal-title":"AIDS Behav"},{"issue":"3","key":"pone.0226614.ref044","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/PHH.0000000000000483","article-title":"Improving Retention in HIV Care Through New York's Expanded Partner Services Data-to-Care Pilot","volume":"23","author":"JM Tesoriero","year":"2017","journal-title":"Journal of Public Health Management and Practice"},{"issue":"13","key":"pone.0226614.ref045","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1056\/NEJM200003303421303","article-title":"Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group","volume":"342","author":"TC Quinn","year":"2000","journal-title":"N Engl J Med"},{"issue":"2","key":"pone.0226614.ref046","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/QAI.0000000000001036","article-title":"Single Viral Load Measurements Overestimate Stable Viral Suppression Among HIV Patients in Care: Clinical and Public Health Implications","volume":"73","author":"G Marks","year":"2016","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"3","key":"pone.0226614.ref047","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1136\/sextrans-2017-053178","article-title":"Characterising HIV transmission risk among US patients with HIV in care: a cross-sectional study of sexual risk behaviour among individuals with viral load above 1500 copies\/mL","volume":"94","author":"MJ Stirratt","year":"2018","journal-title":"Sex Transm Infect"},{"key":"pone.0226614.ref048","unstructured":"New York State Department of Health. Partner Services Data to Care Report, New York State (excluding New York City) 2015 [Agency Report]. 2017. Available from: https:\/\/www.health.ny.gov\/diseases\/aids\/general\/statistics\/docs\/partner_services.pdf."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0226614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T03:30:44Z","timestamp":1613187044000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0226614"}},"subtitle":[],"editor":[{"given":"Joan A.","family":"Cayl\u00e0","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2019,12,18]]},"references-count":48,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,12,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0226614","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2019,12,18]]}}}