{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:35:14Z","timestamp":1791815714582,"version":"4.3.4"},"reference-count":64,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01-AI070921"],"award-info":[{"award-number":["U01-AI070921"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01-AI089878"],"award-info":[{"award-number":["R01-AI089878"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01-AI119012"],"award-info":[{"award-number":["R01-AI119012"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["T32-AG000262"],"award-info":[{"award-number":["T32-AG000262"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0228574","type":"journal-article","created":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T17:32:11Z","timestamp":1585762331000},"page":"e0228574","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["A cross-sectional pilot study of birth mode and vaginal microbiota in reproductive-age women"],"prefix":"10.1371","volume":"15","author":[{"given":"Christina A.","family":"Stennett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8493-5772","authenticated-orcid":true,"given":"Typhanye V.","family":"Dyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney K.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0851-2233","authenticated-orcid":true,"given":"Jacques","family":"Ravel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil G.","family":"Ghanem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca M.","family":"Brotman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,4,1]]},"reference":[{"key":"pone.0228574.ref001","doi-asserted-by":"crossref","first-page":"e1433","DOI":"10.1542\/peds.2009-2260","article-title":"Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children","volume":"125","author":"E Decker","year":"2010","journal-title":"Pediatrics"},{"key":"pone.0228574.ref002","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1007\/s00125-008-0941-z","article-title":"Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies","volume":"51","author":"CR Cardwell","year":"2008","journal-title":"Diabetologia"},{"key":"pone.0228574.ref003","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/j.1365-2222.2008.02939.x","article-title":"Caesarean delivery and risk of atopy and allergic disease: meta-analyses","volume":"38","author":"P Bager","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"pone.0228574.ref004","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/pai.12064","article-title":"Is there an association between microbial exposure and food allergy? A systematic review","volume":"24","author":"T Marrs","year":"2013","journal-title":"Pediatr Allergy Immunol"},{"key":"pone.0228574.ref005","first-page":"1","article-title":"Caesarean section and children\u2019s health: A quasi-experimental design","author":"J Polos","year":"2019","journal-title":"Popul Stud (Camb)"},{"key":"pone.0228574.ref006","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1136\/archdischild-2011-301141","article-title":"Delivery by caesarean section and risk of obesity in preschool age children: a prospective cohort study","volume":"97","author":"SY Huh","year":"2012","journal-title":"Arch Dis Child"},{"key":"pone.0228574.ref007","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/obr.12267","article-title":"Association between caesarean section and childhood obesity: a systematic review and meta-analysis","volume":"16","author":"S Kuhle","year":"2015","journal-title":"Obes Rev"},{"key":"pone.0228574.ref008","article-title":"Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis","volume":"15","author":"OE Keag","year":"2018","journal-title":"PLoS Med"},{"key":"pone.0228574.ref009","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/nrgastro.2012.144","article-title":"Microbial contact during pregnancy, intestinal colonization and human disease","volume":"9","author":"S Rautava","year":"2012","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"pone.0228574.ref010","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1136\/gutjnl-2012-303249","article-title":"Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section","volume":"63","author":"HE Jakobsson","year":"2014","journal-title":"Gut"},{"key":"pone.0228574.ref011","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.chom.2015.04.004","article-title":"Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life","volume":"17","author":"F B\u00e4ckhed","year":"2015","journal-title":"Cell Host Microbe"},{"key":"pone.0228574.ref012","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/MAJ.0b013e31823ea228","article-title":"The Microbiota of the Vagina and Its Influence on Women\u2019s Health and Disease","volume":"343","author":"DH Martin","year":"2012","journal-title":"Am J Med Sci"},{"key":"pone.0228574.ref013","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.2105\/AJPH.91.10.1664","article-title":"Factors linked to bacterial vaginosis in nonpregnant women","volume":"91","author":"BV Study Group","year":"2001","journal-title":"Am J Public Health"},{"key":"pone.0228574.ref014","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1097\/OLQ.0b013e31816907fa","article-title":"A prospective study of risk factors for bacterial vaginosis in HIV-1-seronegative African women","volume":"35","author":"RS McClelland","year":"2008","journal-title":"Sex Transm Dis"},{"key":"pone.0228574.ref015","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1086\/592974","article-title":"Sexual risk factors and bacterial vaginosis: a systematic review and meta-analysis","volume":"47","author":"KA Fethers","year":"2008","journal-title":"Clin Infect Dis"},{"key":"pone.0228574.ref016","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1086\/503780","article-title":"High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence","volume":"193","author":"CS Bradshaw","year":"2006","journal-title":"J Infect Dis"},{"issue":"Suppl 1","key":"pone.0228574.ref017","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.earlhumdev.2010.01.004","article-title":"Mode of delivery affects the bacterial community in the newborn gut","volume":"86","author":"G Biasucci","year":"2010","journal-title":"Early Hum Dev"},{"key":"pone.0228574.ref018","doi-asserted-by":"crossref","first-page":"11971","DOI":"10.1073\/pnas.1002601107","article-title":"Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns","volume":"107","author":"MG Dominguez-Bello","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"pone.0228574.ref019","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1503\/cmaj.121189","article-title":"Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months","volume":"185","author":"MB Azad","year":"2013","journal-title":"CMAJ"},{"key":"pone.0228574.ref020","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1038\/nm.4272","article-title":"Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery","volume":"23","author":"DM Chu","year":"2017","journal-title":"Nat Med"},{"key":"pone.0228574.ref021","doi-asserted-by":"crossref","first-page":"343ra81","DOI":"10.1126\/scitranslmed.aad0917","article-title":"Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability","volume":"8","author":"M Yassour","year":"2016","journal-title":"Sci Transl Med"},{"key":"pone.0228574.ref022","first-page":"A263","article-title":"P591 The effect of hormonal contraception on the vaginal microbiota over 2 years","volume":"95","author":"S Tuddenham","year":"2019","journal-title":"Sex Transm Infect"},{"key":"pone.0228574.ref023","doi-asserted-by":"crossref","first-page":"4680","DOI":"10.1073\/pnas.1002611107","article-title":"Vaginal microbiome of reproductive-age women","volume":"108","author":"J Ravel","year":"2011","journal-title":"PNAS"},{"key":"pone.0228574.ref024","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2049-2618-2-6","article-title":"An improved dual-indexing approach for multiplexed 16S rRNA gene sequencing on the Illumina MiSeq platform","volume":"2","author":"DW Fadrosh","year":"2014","journal-title":"Microbiome"},{"key":"pone.0228574.ref025","first-page":"e00029","article-title":"Ultrahigh-Throughput Multiplexing and Sequencing of &gt;500-Base-Pair Amplicon Regions on the Illumina HiSeq 2500 Platform","volume":"4","author":"JB Holm","year":"2019","journal-title":"mSystems"},{"key":"pone.0228574.ref026","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Na\u00efve Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy","volume":"73","author":"Q Wang","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"pone.0228574.ref027","doi-asserted-by":"crossref","first-page":"D590","DOI":"10.1093\/nar\/gks1219","article-title":"The SILVA ribosomal RNA gene database project: improved data processing and web-based tools","volume":"41","author":"C Quast","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"pone.0228574.ref028","unstructured":"DADA2: High-resolution sample inference from Illumina amplicon data | Nature Methods. [cited 7 Mar 2019]. Available: https:\/\/www.nature.com\/articles\/nmeth.3869"},{"key":"pone.0228574.ref029","unstructured":"speciateIT: 16S rRNA gene Classifier. In: SPECIATEIT: A FAST CLUSTERING-FREE 16S RIBOSOMAL RNA GENE SEQUENCE TAXONOMIC ASSIGNMENT TOOL [Internet]. [cited 5 Mar 2019]. Available: http:\/\/ravel-lab.org\/speciateit"},{"key":"pone.0228574.ref030","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1089\/aid.2018.0304","article-title":"The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission","volume":"35","author":"LR McKinnon","year":"2019","journal-title":"AIDS Res Hum Retroviruses"},{"key":"pone.0228574.ref031","article-title":"Progress Towards an In-Depth Understanding of the Vaginal Microbiome. Keystone Conference: Role of the Genital Tract Microbiome in Sexual and Reproductive Health, Cape Town, South Africa","author":"J. Ravel","year":"2018"},{"key":"pone.0228574.ref032","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014A metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"PA Harris","year":"2009","journal-title":"Journal of Biomedical Informatics"},{"key":"pone.0228574.ref033","doi-asserted-by":"crossref","first-page":"132ra52","DOI":"10.1126\/scitranslmed.3003605","article-title":"Temporal dynamics of the human vaginal microbiota","volume":"4","author":"P Gajer","year":"2012","journal-title":"Sci Transl Med"},{"key":"pone.0228574.ref034","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"N Segata","year":"2011","journal-title":"Genome Biol"},{"key":"pone.0228574.ref035","doi-asserted-by":"crossref","first-page":"c117","DOI":"10.1136\/bmj.c117","article-title":"Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses","volume":"340","author":"X Sun","year":"2010","journal-title":"BMJ"},{"key":"pone.0228574.ref036","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/2049-2618-1-29","article-title":"Daily temporal dynamics of vaginal microbiota before, during and after episodes of bacterial vaginosis","volume":"1","author":"J Ravel","year":"2013","journal-title":"Microbiome"},{"key":"pone.0228574.ref037","doi-asserted-by":"crossref","first-page":"e10197","DOI":"10.1371\/journal.pone.0010197","article-title":"Temporal Variability of Human Vaginal Bacteria and Relationship with Bacterial Vaginosis","volume":"5","author":"S Srinivasan","year":"2010","journal-title":"PLOS ONE"},{"key":"pone.0228574.ref038","doi-asserted-by":"crossref","first-page":"e0116894","DOI":"10.1371\/journal.pone.0116894","article-title":"The vaginal microbiota over an 8- to 10-year period in a cohort of HIV-infected and HIV-uninfected women","volume":"10","author":"SD Mehta","year":"2015","journal-title":"PLoS ONE"},{"key":"pone.0228574.ref039","article-title":"The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women","volume":"2","author":"R Romero","year":"2014"},{"key":"pone.0228574.ref040","doi-asserted-by":"crossref","first-page":"11060","DOI":"10.1073\/pnas.1502875112","article-title":"Temporal and spatial variation of the human microbiota during pregnancy","volume":"112","author":"D DiGiulio","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"pone.0228574.ref041","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/oem.52.8.557","article-title":"Non-differential misclassification and bias towards the null: a clarification","volume":"52","author":"S Wacholder","year":"1995","journal-title":"Occup Environ Med"},{"key":"pone.0228574.ref042","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1086\/657320","article-title":"Bacterial Vaginosis Assessed by Gram Stain and Diminished Colonization Resistance to Incident Gonococcal, Chlamydial, and Trichomonal Genital Infection","volume":"202","author":"RM Brotman","year":"2010","journal-title":"J Infect Dis"},{"key":"pone.0228574.ref043","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1471-2180-12-56","article-title":"BactQuant: An enhanced broad-coverage bacterial quantitative real-time PCR assay","volume":"12","author":"CM Liu","year":"2012","journal-title":"BMC Microbiology"},{"issue":"Suppl 4","key":"pone.0228574.ref044","doi-asserted-by":"crossref","first-page":"S273","DOI":"10.1093\/clinids\/16.Supplement_4.S273","article-title":"The normal vaginal flora, H2O2-producing lactobacilli, and bacterial vaginosis in pregnant women","volume":"16","author":"SL Hillier","year":"1993","journal-title":"Clin Infect Dis"},{"key":"pone.0228574.ref045","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1128\/JCM.00851-09","article-title":"Quantitative PCR assessments of bacterial species in women with and without bacterial vaginosis","volume":"48","author":"M Zozaya-Hinchliffe","year":"2010","journal-title":"J Clin Microbiol"},{"key":"pone.0228574.ref046","doi-asserted-by":"crossref","first-page":"e60670","DOI":"10.1371\/journal.pone.0060670","article-title":"Composition of the vaginal microbiota in women of reproductive age\u2014sensitive and specific molecular diagnosis of bacterial vaginosis is possible?","volume":"8","author":"E Shipitsyna","year":"2013","journal-title":"PLoS ONE"},{"key":"pone.0228574.ref047","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1128\/CMR.00075-15","article-title":"The Human Microbiome during Bacterial Vaginosis","volume":"29","author":"AB Onderdonk","year":"2016","journal-title":"Clinical Microbiology Reviews"},{"key":"pone.0228574.ref048","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.immuni.2015.04.019","article-title":"Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract","volume":"42","author":"MN Anahtar","year":"2015","journal-title":"Immunity"},{"key":"pone.0228574.ref049","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.chom.2016.11.010","article-title":"Prevotella as a Hub for Vaginal Microbiota under the Influence of Host Genetics and Their Association with Obesity","volume":"21","author":"J Si","year":"2017","journal-title":"Cell Host Microbe"},{"key":"pone.0228574.ref050","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.2105\/AJPH.84.11.1761","article-title":"Mother-daughter correlations of obesity and cardiovascular disease risk factors in black and white households: the NHLBI Growth and Health Study","volume":"84","author":"JA Morrison","year":"1994","journal-title":"Am J Public Health"},{"key":"pone.0228574.ref051","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1056\/NEJM199709253371301","article-title":"Predicting obesity in young adulthood from childhood and parental obesity","volume":"337","author":"RC Whitaker","year":"1997","journal-title":"N Engl J Med"},{"key":"pone.0228574.ref052","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S1701-2163(16)34876-9","article-title":"Higher caesarean section rates in women with higher body mass index: are we managing labour differently?","volume":"33","author":"HA Abenhaim","year":"2011","journal-title":"J Obstet Gynaecol Can"},{"key":"pone.0228574.ref053","first-page":"35","article-title":"Association between cesarean delivery rate and body mass index","volume":"106","author":"JA Berendzen","year":"2013","journal-title":"Tenn Med"},{"key":"pone.0228574.ref054","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/ijo.2016.219","article-title":"Does vaginal delivery mitigate or strengthen the intergenerational association of overweight and obesity? Findings from the Boston Birth Cohort","volume":"41","author":"NT Mueller","year":"2017","journal-title":"Int J Obes (Lond)"},{"key":"pone.0228574.ref055","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1056\/NEJM198907273210406","article-title":"Socioeconomic differences in rates of cesarean section","volume":"321","author":"JB Gould","year":"1989","journal-title":"N Engl J Med"},{"key":"pone.0228574.ref056","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1097\/OLQ.0b013e318074e565","article-title":"The prevalence of bacterial vaginosis in the United States, 2001\u20132004; associations with symptoms, sexual behaviors, and reproductive health","volume":"34","author":"EH Koumans","year":"2007","journal-title":"Sex Transm Dis"},{"key":"pone.0228574.ref057","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.tim.2012.12.001","article-title":"de La Cochetiere M-F. Development of intestinal microbiota in infants and its impact on health","volume":"21","author":"S Matamoros","year":"2013","journal-title":"Trends Microbiol"},{"key":"pone.0228574.ref058","doi-asserted-by":"crossref","first-page":"763","DOI":"10.3920\/BM2017.0064","article-title":"Does the maternal vaginal microbiota play a role in seeding the microbiota of neonatal gut and nose?","volume":"8","author":"O Sakwinska","year":"2017","journal-title":"Benef Microbes"},{"key":"pone.0228574.ref059","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s40168-015-0126-1","article-title":"The first microbial environment of infants born by C-section: the operating room microbes","volume":"3","author":"H Shin","year":"2015","journal-title":"Microbiome"},{"issue":"Suppl 2","key":"pone.0228574.ref060","doi-asserted-by":"crossref","first-page":"S269","DOI":"10.1093\/clinids\/20.Supplement_2.S269","article-title":"Anaerobes predominate among the vaginal microflora of prepubertal girls","volume":"20","author":"GB Hill","year":"1995","journal-title":"Clin Infect Dis"},{"key":"pone.0228574.ref061","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00097-15","article-title":"Vaginal microbiota of adolescent girls prior to the onset of menarche resemble those of reproductive-age women","volume":"6","author":"RJ Hickey","year":"2015","journal-title":"MBio"},{"key":"pone.0228574.ref062","doi-asserted-by":"crossref","first-page":"120.e1","DOI":"10.1016\/j.ajog.2010.07.010","article-title":"Contemporary perspectives on vaginal pH and lactobacilli","volume":"204","author":"IM Linhares","year":"2011","journal-title":"Am J Obstet Gynecol"},{"key":"pone.0228574.ref063","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1038\/nm.4039","article-title":"Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer","volume":"22","author":"MG Dominguez-Bello","year":"2016","journal-title":"Nat Med"},{"issue":"Suppl 1","key":"pone.0228574.ref064","doi-asserted-by":"crossref","first-page":"S29","DOI":"10.1093\/infdis\/jiw140","article-title":"The Interplay of Host Immunity, Environment and the Risk of Bacterial Vaginosis and Associated Reproductive Health Outcomes","volume":"214","author":"K Murphy","year":"2016","journal-title":"J Infect Dis"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0228574","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T17:32:35Z","timestamp":1585762355000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0228574"}},"subtitle":[],"editor":[{"given":"Tania","family":"Crucitti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,4,1]]},"references-count":64,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,4,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0228574","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,1]]}}}