{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T06:25:39Z","timestamp":1781245539004,"version":"3.54.1"},"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T00:00:00Z","timestamp":1583971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0229837","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T17:45:15Z","timestamp":1584035115000},"page":"e0229837","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Direct transmission via households informs models of disease and intervention dynamics in cholera"],"prefix":"10.1371","volume":"15","author":[{"given":"Victor A.","family":"Meszaros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miles D.","family":"Miller-Dickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Baffour-Awuah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1121-1204","authenticated-orcid":true,"given":"Salvador","family":"Almagro-Moreno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1581-8345","authenticated-orcid":true,"given":"C. Brandon","family":"Ogbunugafor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,3,12]]},"reference":[{"issue":"10101","key":"pone.0229837.ref001","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/S0140-6736(17)30559-7","article-title":"Cholera","volume":"390","author":"JD Clemens","year":"2017","journal-title":"The Lancet"},{"issue":"1","key":"pone.0229837.ref002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3201\/eid1301.060779","article-title":"Epidemics after natural disasters","volume":"13","author":"JT Watson","year":"2007","journal-title":"Emerging infectious diseases"},{"issue":"05","key":"pone.0229837.ref003","doi-asserted-by":"crossref","first-page":"397","DOI":"10.3855\/jidc.10129","article-title":"Yemen: cholera outbreak and the ongoing armed conflict","volume":"12","author":"FA Dureab","year":"2018","journal-title":"The Journal of Infection in Developing Countries"},{"issue":"1","key":"pone.0229837.ref004","first-page":"1635","article-title":"Vibrio cholerae Transmits through Water among the Household Contacts of Cholera Patients in Cholera Endemic Coastal Villages of Bangladesh, 2015-2016 (CHoBI7 Trial)","volume":"6","author":"Z Rahman","year":"2018","journal-title":"Frontiers in Public Health"},{"issue":"1","key":"pone.0229837.ref005","first-page":"1635","article-title":"Transmission of infectious Vibrio cholerae through drinking water among the household contacts of cholera patients (CHoBI7 trial)","volume":"7","author":"R Rafique","year":"2016","journal-title":"Frontiers in Microbiology"},{"issue":"7","key":"pone.0229837.ref006","doi-asserted-by":"crossref","first-page":"e0006641","DOI":"10.1371\/journal.pntd.0006641","article-title":"A prospective cohort study comparing household contact and water Vibrio cholerae isolates in households of cholera patients in rural Bangladesh","volume":"12","author":"CM George","year":"2018","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"11","key":"pone.0229837.ref007","doi-asserted-by":"crossref","first-page":"e3314","DOI":"10.1371\/journal.pntd.0003314","article-title":"Household Transmission of Vibrio cholerae in Bangladesh","volume":"8","author":"JD Sugimoto","year":"2014","journal-title":"PLOS Neglected Tropical Diseases"},{"key":"pone.0229837.ref008","doi-asserted-by":"crossref","unstructured":"Kuhl ME, Crooks A, Hailegiorgis A. Disease modeling within refugee camps: A multi-agent systems approach. Proceedings of the 2013 Winter Simulation Conference. Simulation: Making Decisions in a Complex World. 2013 Dec:1697\u20131706.","DOI":"10.1109\/WSC.2013.6721551"},{"issue":"1075","key":"pone.0229837.ref009","first-page":"1","article-title":"Comparing alternative cholera vaccination strategies in Maela refugee camp: using a transmission model in public health practice","volume":"19","author":"J Havumaki","year":"2019","journal-title":"BMC Infectious Diseases"},{"issue":"9773","key":"pone.0229837.ref010","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1016\/S0140-6736(11)60273-0","article-title":"Transmission dynamics and control of cholera in Haiti: an epidemic model","volume":"377","author":"JR Andrews","year":"2011","journal-title":"The Lancet"},{"issue":"1","key":"pone.0229837.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2334-1-1","article-title":"Endemic and epidemic dynamics of cholera: the role of the aquatic reservoir","volume":"1","author":"CT Code\u00e7o","year":"2001","journal-title":"BMC Infectious Diseases"},{"issue":"43","key":"pone.0229837.ref012","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1098\/rsif.2009.0204","article-title":"On spatially explicit models of cholera epidemics","volume":"7","author":"E Bertuzzo","year":"2009","journal-title":"Journal of the Royal Society Interface"},{"issue":"9","key":"pone.0229837.ref013","doi-asserted-by":"crossref","first-page":"593","DOI":"10.7326\/0003-4819-154-9-201105030-00334","article-title":"Cholera epidemic in Haiti, 2010: using a transmission model to explain spatial spread of disease and identify optimal control interventions","volume":"154","year":"2011","journal-title":"Annals of internal medicine"},{"issue":"67","key":"pone.0229837.ref014","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1098\/rsif.2011.0304","article-title":"Modelling cholera epidemics: the role of waterways, human mobility and sanitation","volume":"9","author":"L Mari","year":"2012","journal-title":"Journal of the Royal Society Interface"},{"issue":"1","key":"pone.0229837.ref015","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.mbs.2013.08.003","article-title":"A cholera model in a patchy environment with water and human movement","volume":"246","author":"MC Eisenberg","year":"2013","journal-title":"Mathematical Biosciences"},{"issue":"1","key":"pone.0229837.ref016","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cnsns.2016.10.007","article-title":"Transmission dynamics of cholera: Mathematical modeling and control strategies","volume":"45","author":"GQ Sun","year":"2017","journal-title":"Communications in Nonlinear Science and Numerical Simulation"},{"issue":"1","key":"pone.0229837.ref017","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/17513758.2015.1039608","article-title":"An evolutionary computing approach for parameter estimation investigation of a model for cholera","volume":"9","author":"O Akman","year":"2016","journal-title":"Journal of Biological Dynamics"},{"issue":"1","key":"pone.0229837.ref018","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/23737867.2016.1211495","article-title":"Examination of models for cholera: insights into model comparison methods","volume":"3","author":"O Akman","year":"2016","journal-title":"Letters in Biomathematics"},{"issue":"8","key":"pone.0229837.ref019","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1007\/s11538-010-9521-8","article-title":"Modeling Optimal Intervention Strategies for Cholera","volume":"72","author":"RM Neilan","year":"2010","journal-title":"Bulletin of Mathematical Biology"},{"issue":"3","key":"pone.0229837.ref020","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.biosystems.2011.04.001","article-title":"Mathematical analysis of a cholera model with public health interventions","volume":"105","author":"A Mwasa","year":"2011","journal-title":"Journal of Biosystems"},{"issue":"4","key":"pone.0229837.ref021","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1142\/S021833901340007X","article-title":"Modeling Cholera Disease With Education And Chlorination","volume":"21","author":"M Al-Arydah","year":"2013","journal-title":"Journal of Biological Systems"},{"issue":"6","key":"pone.0229837.ref022","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1007\/s11538-010-9507-6","article-title":"Multiple transmission pathways and disease dynamics in a waterborne pathogen model","volume":"72","author":"JH Tien","year":"2010","journal-title":"Bulletin of Mathematical Biology"},{"issue":"2","key":"pone.0229837.ref023","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.mbs.2011.09.003","article-title":"Global dynamics of cholera models with differential infectivity","volume":"234","author":"Z Shuai","year":"2011","journal-title":"Mathematical Biosciences"},{"issue":"4","key":"pone.0229837.ref024","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1007\/s00285-014-0839-y","article-title":"Model for disease dynamics of a waterborne pathogen on a random network","volume":"71","author":"M Li","year":"2015","journal-title":"Journal of Mathematical Biology"},{"issue":"1","key":"pone.0229837.ref025","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1371\/journal.pmed.0030007","article-title":"Hyperinfectivity: A Critical Element in the Ability of V. cholerae to Cause Epidemics?","volume":"3","author":"DM Hartley","year":"2005","journal-title":"PLOS Medicine"},{"key":"pone.0229837.ref026","unstructured":"Department of Economic and Social Affairs, Population Division. World Population Prospects The 2008 Revision, Highlights, Working Paper. The United Nations. 2008."},{"key":"pone.0229837.ref027","unstructured":"the United Nations Children\u2019s Fund (UNICEF). Minist\u00e8re De La Sant\u00e9du Cameroun, Donn\u00e9es Chol\u00e9ra UNICEF. 2014."},{"issue":"4","key":"pone.0229837.ref028","first-page":"610","article-title":"Effects of doxycycline in actively purging cholera patients: A double-blind clinical trial","volume":"10","author":"MM Rahaman","year":"1976","journal-title":"American Society for Microbiology"},{"issue":"1","key":"pone.0229837.ref029","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.cnsns.2018.06.023","article-title":"Mathematical Assessment of the Role of Environmental Factors on the Dynamical transmission of Cholera","volume":"67","author":"G Kolaye","year":"2019","journal-title":"Communications in Nonlinear Science and Numerical Simulation"},{"issue":"3","key":"pone.0229837.ref030","first-page":"359","article-title":"Cholera Vaccine Field Trials in East Pakistan. 2. Effectiveness in the Field","volume":"38","author":"AS Benenson","year":"1968","journal-title":"Bull World Health Organization"},{"issue":"1","key":"pone.0229837.ref031","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1128\/CMR.8.1.48","article-title":"Cholera","volume":"8","author":"JB Kaper","year":"1995","journal-title":"Clin Microbiol Rev"},{"issue":"1","key":"pone.0229837.ref032","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1128\/IAI.56.1.161-167.1988","article-title":"Volunteer studies of deletion mutants of Vibrio cholerae O1 prepared by recombinant techniques","volume":"56","author":"MM Levin","year":"1988","journal-title":"Infect Immun"},{"issue":"Suppl 121","key":"pone.0229837.ref033","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1093\/infdis\/121.Supplement.S10","article-title":"The spectrum of cholera in rural East Pakistan. I. Correlation of bacteriologic and serologic results","volume":"121","author":"WE Woodward","year":"1970","journal-title":"J Infect Dis"},{"issue":"20","key":"pone.0229837.ref034","doi-asserted-by":"crossref","first-page":"4297","DOI":"10.1016\/j.vaccine.2006.03.008","article-title":"Long-term effectiveness against cholera of oral killed whole-cell vaccine produced in Vietnam","volume":"24","author":"VD Thiem","year":"2006","journal-title":"Vaccine"},{"issue":"10","key":"pone.0229837.ref035","first-page":"e1289","article-title":"Efficacy and safety of a modified killed-whole-cell oral cholera vaccine in India: An interim analysis of a cluster-randomized, double-blind, placebo-controlled trial","volume":"5","author":"D Sur","year":"2011","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"18","key":"pone.0229837.ref036","first-page":"1","article-title":"Cholera and Post Earthquake Response in Haiti","volume":"1","author":"DM Hartly","year":"2011","journal-title":"World Health Organization: Pan American Health Organization"},{"issue":"4","key":"pone.0229837.ref037","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s13312-010-0054-x","article-title":"Single-dose azithromycin for childhood cholera","volume":"47","year":"2010","journal-title":"Indian Pediatrics"},{"key":"pone.0229837.ref038","unstructured":"US Army Corps of Engineers Mobile District and Topographic Engineering Center Water Resources Assessment of Haiti. US Army. 1999 Aug."},{"issue":"2","key":"pone.0229837.ref039","doi-asserted-by":"crossref","first-page":"0003","DOI":"10.1128\/microbiolspec.OH-0003-2012","article-title":"Cholera: environmental reservoirs and impact on disease transmission","volume":"1","author":"S Almagro-Moreno","year":"2013","journal-title":"Microbiol Spectr"},{"issue":"2","key":"pone.0229837.ref040","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2307\/1403510","article-title":"Sensitivity and Uncertainty Analysis of Complex Models of Disease Transmission: An HIV Model, as an Example","volume":"62","author":"S Blower","year":"1994","journal-title":"International Statistical Review"},{"key":"pone.0229837.ref041","unstructured":"Holland J. Notes on R0. Unplublished. Stanford University: Department of Anthropological Sciences. May 2007."},{"issue":"1","key":"pone.0229837.ref042","first-page":"12","article-title":"Domestic Water Source, Sanitation and High Risk of Bacteriological Diseases in the Urban Slum: Case of Cholera in Makoko, Lagos, Nigeria","volume":"2","author":"AO Ayeni","year":"2014","journal-title":"Journal of Environment Pollution and Human Health"},{"issue":"47","key":"pone.0229837.ref043","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1098\/rsif.2009.0386","article-title":"The construction of next-generation matrices for compartmental epidemic models","volume":"7","author":"O Diekmann","year":"2010","journal-title":"Journal of Royal Society Interface"},{"issue":"10","key":"pone.0229837.ref044","doi-asserted-by":"crossref","first-page":"6674","DOI":"10.1128\/IAI.73.10.6674-6679.2005","article-title":"Hyperinfectivity of Human-Passaged Vibrio cholerae Can Be Modeled by Growth in the Infant Mouse","volume":"73","author":"A Alam","year":"2005","journal-title":"Infection and Immunity"},{"issue":"1","key":"pone.0229837.ref045","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nature00778","article-title":"Host-induced epidemic spread of the cholera bacterium","volume":"417","author":"DS Merrell","year":"2002","journal-title":"Nature"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0229837","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T16:49:47Z","timestamp":1666111787000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0229837"}},"subtitle":[],"editor":[{"given":"Abdallah M.","family":"Samy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,3,12]]},"references-count":45,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0229837","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,12]]}}}