{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:43:46Z","timestamp":1790743426406,"version":"4.1.0"},"reference-count":119,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2020,3,23]],"date-time":"2020-03-23T00:00:00Z","timestamp":1584921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0230194","type":"journal-article","created":{"date-parts":[[2020,3,23]],"date-time":"2020-03-23T17:29:32Z","timestamp":1584984572000},"page":"e0230194","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Psychosocial assessment of families caring for a child with acute lymphoblastic leukemia, epilepsy or asthma: Psychosocial risk as network of interacting symptoms"],"prefix":"10.1371","volume":"15","author":[{"given":"Chiara","family":"Colliva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Cellini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Dalla Porta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara Maria","family":"Bergamini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azzurra","family":"Guerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Di Giuseppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Caprino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Benatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0958-7333","authenticated-orcid":true,"given":"Fabio","family":"Tascedda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4974-1964","authenticated-orcid":true,"given":"Johanna M. C.","family":"Blom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,3,23]]},"reference":[{"key":"pone.0230194.ref001","volume-title":"Mental, Neurological, and Substance Use Disorders: Disease Control Priorities","author":"JG Scott","year":"2016"},{"key":"pone.0230194.ref002","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.jpsychires.2010.01.004","article-title":"Chronic childhood adversity and onset of psychopathology during three life stages: childhood, adolescence and adulthood","volume":"44","author":"C Benjet","year":"2010","journal-title":"J Psychiatr Res"},{"key":"pone.0230194.ref003","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1365-2214.2006.00591.x","article-title":"The psychosocial well-being of children with chronic disease, their parents and siblings: an overview of the research evidence base. Child: Care","volume":"32","author":"JH Barlow","year":"2006","journal-title":"Health and Development"},{"key":"pone.0230194.ref004","doi-asserted-by":"crossref","first-page":"787","DOI":"10.2147\/IJGM.S45156","article-title":"The impact of patients\u2019 chronic disease on family quality of life: an experience from 26 specialties","volume":"6","author":"CJ Golics","year":"2013","journal-title":"Int J Gen Med"},{"key":"pone.0230194.ref005","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.pec.2016.08.011","article-title":"Parenting a child with chronic illness as they transition into adulthood: A systematic review and thematic synthesis of parents\u2019 experiences","volume":"100","author":"G Heath","year":"2017","journal-title":"Patient Education and Counseling"},{"key":"pone.0230194.ref006","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/DBP.0b013e3181c7226b","article-title":"Family functioning in the context of pediatric chronic conditions","volume":"31","author":"M Herzer","year":"2010","journal-title":"J Dev Behav Pediatr"},{"key":"pone.0230194.ref007","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1037\/0893-3200.21.3.407","article-title":"A meta-analytic review of the influence of pediatric cancer on parent and family functioning","volume":"21","author":"ALH Pai","year":"2007","journal-title":"J Fam Psychol"},{"key":"pone.0230194.ref008","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1111\/j.1528-1167.2012.03706.x","article-title":"Neurocognitive profiles in children with epilepsy","volume":"53","author":"CL Kernan","year":"2012","journal-title":"Epilepsia"},{"key":"pone.0230194.ref009","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1542\/peds.112.6.1338","article-title":"Not only a matter of epilepsy: early problems of cognition and behavior in children with \u201cepilepsy only\u201d\u2014a prospective, longitudinal, controlled study starting at diagnosis","volume":"112","author":"KJ Oostrom","year":"2003","journal-title":"Pediatrics"},{"key":"pone.0230194.ref010","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.yebeh.2016.02.032","article-title":"Graph theory and cognition: A complementary avenue for examining neuropsychological status in epilepsy","volume":"64","author":"C Garcia-Ramos","year":"2016","journal-title":"Epilepsy & Behavior"},{"key":"pone.0230194.ref011","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1469-8749.2007.00493.x","article-title":"Psychiatric comorbidity in children with new onset epilepsy","volume":"49","author":"JE Jones","year":"2007","journal-title":"Developmental Medicine & Child Neurology"},{"key":"pone.0230194.ref012","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1111\/epi.13766","article-title":"Psychiatric and Behavioral Comorbidities in Epilepsy: A Critical Reappraisal","volume":"58","author":"AT Berg","year":"2017","journal-title":"Epilepsia"},{"key":"pone.0230194.ref013","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1016\/j.neubiorev.2012.06.003","article-title":"Neurocircuitry models of posttraumatic stress disorder and beyond: a meta-analysis of functional neuroimaging studies","volume":"36","author":"R Patel","year":"2012","journal-title":"Neurosci Biobehav Rev"},{"key":"pone.0230194.ref014","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1037\/a0013169","article-title":"Symptom perception in children with asthma: cognitive and psychological factors","volume":"28","author":"D Koinis-Mitchell","year":"2009","journal-title":"Health Psychol"},{"key":"pone.0230194.ref015","doi-asserted-by":"crossref","first-page":"792","DOI":"10.3109\/02770903.2010.491148","article-title":"The Association Between Symptomatic Asthma and Neurobehavioral Comorbidities Among Children","volume":"47","author":"AA Arif","year":"2010","journal-title":"Journal of Asthma"},{"key":"pone.0230194.ref016","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1192\/bjpo.bp.115.000182","article-title":"Unrecognised psychopathology in patients with difficult asthma: major mental and personality disorders","volume":"1","author":"LCJ Prins","year":"2015","journal-title":"BJPsych Open"},{"key":"pone.0230194.ref017","doi-asserted-by":"crossref","first-page":"e0211053","DOI":"10.1371\/journal.pone.0211053","article-title":"A network analysis approach to ADHD symptoms: More than the sum of its parts","volume":"14","author":"TJ Silk","year":"2019","journal-title":"PLoS ONE"},{"key":"pone.0230194.ref018","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.yebeh.2016.02.032","article-title":"Graph Theory and Cognition: An Alternative Avenue for Examining Neuropsychological Status in Epilepsy","volume":"64","author":"C Garcia-Ramos","year":"2016","journal-title":"Epilepsy Behav"},{"key":"pone.0230194.ref019","first-page":"1","article-title":"It takes a village\u2014asthma networks utilized by parents when managing childhood asthma medications","volume":"0","author":"P Srour-Alphonse","year":"2019","journal-title":"Journal of Asthma"},{"key":"pone.0230194.ref020","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1093\/jpepsy\/jsq004","article-title":"Course and Predictors of Posttraumatic Stress Disorder in Parents after Pediatric Intensive Care Treatment of their Child","volume":"35","author":"MB Bronner","year":"2010","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref021","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1093\/jpepsy\/27.8.699","article-title":"Siblings of Children With a Chronic Illness: A Meta-Analysis","volume":"27","author":"D Sharpe","year":"2002","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref022","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s10567-010-0082-z","article-title":"Family Adjustment to Childhood Cancer: A Systematic Review","volume":"14","author":"KA Long","year":"2011","journal-title":"Clin Child Fam Psychol Rev"},{"key":"pone.0230194.ref023","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1469-7610.2011.02520.x","article-title":"The mutual prospective influence of child and parental post-traumatic stress symptoms in pediatric patients","volume":"53","author":"MA Landolt","year":"2012","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"pone.0230194.ref024","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.iac.2016.03.012","article-title":"Psychosocial Factors in Severe Pediatric Asthma","volume":"36","author":"GD Booster","year":"2016","journal-title":"Immunology and Allergy Clinics of North America"},{"key":"pone.0230194.ref025","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5698\/1535-7597-15.1.13","article-title":"Epilepsy and Parent Stress: The Chicken and the Egg Dilemma","volume":"15","author":"R Caplan","year":"2015","journal-title":"Epilepsy Curr"},{"key":"pone.0230194.ref026","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1053\/jpdn.2003.11","article-title":"Managing side effects of childhood cancer treatment","volume":"18","author":"R. Bryant","year":"2003","journal-title":"Journal of Pediatric Nursing"},{"key":"pone.0230194.ref027","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/S0885-3924(03)00285-9","article-title":"A different perspective to approaching cancer symptoms in children","volume":"26","author":"RL Woodgate","year":"2003","journal-title":"J Pain Symptom Manage"},{"key":"pone.0230194.ref028","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s40413-017-0169-9","article-title":"Psychological and lifestyle risk factors for asthma exacerbations and morbidity in children","volume":"10","author":"AA Oland","year":"2017","journal-title":"World Allergy Organization Journal"},{"key":"pone.0230194.ref029","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.yebeh.2019.01.039","article-title":"Correlates of quality of life in mothers of children with diagnosed epilepsy","volume":"93","author":"OE Edelstein","year":"2019","journal-title":"Epilepsy & Behavior"},{"key":"pone.0230194.ref030","doi-asserted-by":"crossref","first-page":"4339","DOI":"10.1002\/cncr.24587","article-title":"Family psychosocial risk, distress, and service utilization in pediatric cancer","volume":"115","author":"MA Alderfer","year":"2009","journal-title":"Cancer"},{"key":"pone.0230194.ref031","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/S0885-3924(03)00285-9","article-title":"A different perspective to approaching cancer symptoms in children","volume":"26","author":"RL Woodgate","year":"2003","journal-title":"Journal of Pain and Symptom Management"},{"key":"pone.0230194.ref032","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.psc.2007.07.009","article-title":"Late Consequences of Chronic Pediatric Illness","volume":"30","author":"S Turkel","year":"2007","journal-title":"Psychiatric Clinics of North America"},{"key":"pone.0230194.ref033","doi-asserted-by":"crossref","first-page":"478","DOI":"10.3892\/etm.2017.4526","article-title":"Chronic conditions in adolescents","volume":"14","author":"M Jin","year":"2017","journal-title":"Exp Ther Med"},{"key":"pone.0230194.ref034","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1007\/s10578-016-0684-x","article-title":"Biopsychosocial Approach to Risk and Resilience on Behavior in Children Followed from Birth to Age 12","volume":"48","author":"S Agnafors","year":"2017","journal-title":"AChild Psychiatry Hum Dev"},{"key":"pone.0230194.ref035","first-page":"33","article-title":"Impact of Survivorship Care on Young Adult Survivors of Childhood Cancer With Post-Traumatic Stress Symptoms","volume":"46","author":"WL Ross","year":"2019","journal-title":"Oncol Nurs Forum"},{"key":"pone.0230194.ref036","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2016.00287","article-title":"Post-traumatic Stress Symptoms and Post-traumatic Growth in 223 Childhood Cancer Survivors: Predictive Risk Factors","volume":"7","author":"M Tremolada","year":"2016","journal-title":"Front Psychol"},{"key":"pone.0230194.ref037","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/pon.4141","article-title":"Infancy and pediatric cancer: an exploratory study of parent psychological distress","volume":"26","author":"L Vernon","year":"2017","journal-title":"Psycho-Oncology"},{"key":"pone.0230194.ref038","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ejon.2018.04.004","article-title":"A systematic scoping review of the recent literature (\u223c2011\u20132017) about the costs of illness to parents of children diagnosed with cancer","volume":"35","author":"SJ Santacroce","year":"2018","journal-title":"European Journal of Oncology Nursing"},{"key":"pone.0230194.ref039","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/S0140-6736(07)60370-5","article-title":"Adolescents with a chronic condition: challenges living, challenges treating","volume":"369","author":"SM Sawyer","year":"2007","journal-title":"The Lancet"},{"key":"pone.0230194.ref040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cortex.2015.02.001","article-title":"Mapping the landscape of cognitive development in children with epilepsy","volume":"66","author":"TS Kellermann","year":"2015","journal-title":"Cortex"},{"key":"pone.0230194.ref041","first-page":"1153","article-title":"Screening for Psychosocial Disorders in Pediatric Practice","volume":"142","author":"MS Jellinek","year":"1988","journal-title":"Am J Dis Child"},{"key":"pone.0230194.ref042","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3109\/0284186X.2014.995774","article-title":"Family psychosocial risk screening guided by the Pediatric Psychosocial Preventative Health Model (PPPHM) using the Psychosocial Assessment Tool (PAT)","volume":"54","author":"AE Kazak","year":"2015","journal-title":"Acta Oncologica"},{"key":"pone.0230194.ref043","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.jpeds.2013.06.028","article-title":"Psychological and quality of life outcomes in pediatric populations: a parent-child perspective","volume":"163","author":"H Moreira","year":"2013","journal-title":"J Pediatr"},{"key":"pone.0230194.ref044","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jpeds.2018.02.071","article-title":"Impact of Psychosocial Risk on Outcomes among Families Seeking Treatment for Obesity","volume":"198","author":"T-LT Phan","year":"2018","journal-title":"The Journal of Pediatrics"},{"key":"pone.0230194.ref045","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ynstr.2018.05.002","article-title":"Network-based approaches to examining stress in the adolescent brain","volume":"8","author":"TC Ho","year":"2018","journal-title":"Neurobiology of Stress"},{"key":"pone.0230194.ref046","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.neuron.2017.11.007","article-title":"From Maps to Multi-dimensional Network Mechanisms of Mental Disorders","volume":"97","author":"U Braun","year":"2018","journal-title":"Neuron"},{"key":"pone.0230194.ref047","doi-asserted-by":"crossref","first-page":"8685","DOI":"10.1073\/pnas.0701361104","article-title":"The human disease network","volume":"104","author":"K-I Goh","year":"2007","journal-title":"PNAS"},{"key":"pone.0230194.ref048","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.jad.2015.09.005","article-title":"What are \u201cgood\u201d depression symptoms? Comparing the centrality of DSM and non-DSM symptoms of depression in a network analysis","volume":"189","author":"EI Fried","year":"2016","journal-title":"Journal of Affective Disorders"},{"key":"pone.0230194.ref049","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00127-016-1319-z","article-title":"Mental disorders as networks of problems: A review of recent insights","volume":"52","author":"EI Fried","year":"2017","journal-title":"Social Psychiatry and Psychiatric Epidemiology: The International Journal for Research in Social and Genetic Epidemiology and Mental Health Services"},{"key":"pone.0230194.ref050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/00273171.2019.1614898","article-title":"Bridge Centrality: A Network Approach to Understanding Comorbidity","volume":"0","author":"PJ Jones","year":"2019","journal-title":"Multivariate Behavioral Research"},{"key":"pone.0230194.ref051","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2017.01305","article-title":"Commentary: A network theory of mental disorders","volume":"8","author":"PJ Jones","year":"2017","journal-title":"Front Psychol"},{"key":"pone.0230194.ref052","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.tics.2017.03.002","article-title":"Network Model of the Emotional Brain","volume":"21","author":"L Pessoa","year":"2017","journal-title":"ATrends in Cognitive Sciences"},{"key":"pone.0230194.ref053","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1177\/1073858416671936","article-title":"Dynamic Networks in the Emotional Brain","volume":"23","author":"L Pessoa","year":"2017","journal-title":"Neuroscientist"},{"key":"pone.0230194.ref054","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1177\/1073858416667720","article-title":"Small-World Brain Networks Revisited","volume":"23","author":"DS Bassett","year":"2017","journal-title":"Neuroscientist"},{"key":"pone.0230194.ref055","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1103\/RevModPhys.74.47","article-title":"Statistical mechanics of complex networks","volume":"74","author":"R Albert","year":"2002","journal-title":"Rev Mod Phys"},{"key":"pone.0230194.ref056","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1126\/science.1171022","article-title":"Revisiting the Foundations of Network Analysis","volume":"325","author":"CT Butts","year":"2009","journal-title":"Science"},{"key":"pone.0230194.ref057","doi-asserted-by":"crossref","DOI":"10.1093\/acprof:oso\/9780199206650.001.0001","volume-title":"Networks: An Introduction","author":"M Newman","year":"2010"},{"key":"pone.0230194.ref058","volume-title":"Graphentheory","author":"R Diestel","year":"2000"},{"key":"pone.0230194.ref059","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1049\/iet-syb:20060038","article-title":"Graph theory and networks in Biology","volume":"1","author":"O Mason","year":"2007","journal-title":"IET Systems Biology"},{"key":"pone.0230194.ref060","volume-title":"Principles of animal communication","author":"JW Bradbury","year":"2011"},{"key":"pone.0230194.ref061","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nn.4502","article-title":"Network neuroscience","volume":"20","author":"DS Bassett","year":"2017","journal-title":"Nat Neurosci"},{"key":"pone.0230194.ref062","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1001\/jamapsychiatry.2014.35","article-title":"Neuroimaging Evidence for a Role of Neural Social Stress Processing in Ethnic Minority\u2013Associated Environmental Risk","volume":"71","author":"C Akdeniz","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"pone.0230194.ref063","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/7854_2018_41","volume-title":"Biomarkers in Psychiatry","author":"DM Lydon-Staley","year":"2018"},{"key":"pone.0230194.ref064","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1146\/annurev-clinpsy-050212-185608","article-title":"Network Analysis: An Integrative Approach to the Structure of Psychopathology","volume":"9","author":"D Borsboom","year":"2013","journal-title":"Annual Review of Clinical Psychology"},{"key":"pone.0230194.ref065","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.cobeha.2017.09.005","article-title":"Understanding emotion with brain networks","volume":"19","author":"L Pessoa","year":"2018","journal-title":"Current Opinion in Behavioral Sciences"},{"key":"pone.0230194.ref066","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0112734","article-title":"A Network View on Psychiatric Disorders: Network Clusters of Symptoms as Elementary Syndromes of Psychopathology","volume":"9","author":"R Goekoop","year":"2014","journal-title":"PLoS One"},{"key":"pone.0230194.ref067","first-page":"119","article-title":"Social challenges of contemporary psychiatry","volume":"28","author":"N Bouras","year":"2017","journal-title":"Psychiatrike = Psychiatriki"},{"key":"pone.0230194.ref068","doi-asserted-by":"crossref","first-page":"15608","DOI":"10.1038\/s41598-017-15753-3","article-title":"Health and disease phenotyping in old age using a cluster network analysis","volume":"7","author":"JF Valenzuela","year":"2017","journal-title":"Scientific Reports"},{"key":"pone.0230194.ref069","unstructured":"Global Initiative for Asthma. In: Global Initiative for Asthma\u2014GINA [Internet]. [cited 11 Dec 2018]. Available: https:\/\/ginasthma.org\/"},{"key":"pone.0230194.ref070","unstructured":"GINA eBooks. In: Global Initiative for Asthma\u2014GINA [Internet]. [cited 16 Jul 2019]. Available: https:\/\/ginasthma.org\/gina-ebooks\/"},{"key":"pone.0230194.ref071","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/epi.13709","article-title":"ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology","volume":"58","author":"IE Scheffer","year":"2017","journal-title":"Epilepsia"},{"key":"pone.0230194.ref072","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1111\/j.1528-1167.2006.00215.x","article-title":"Report of the ILAE Classification Core Group","volume":"47","author":"J Engel","year":"2006","journal-title":"Epilepsia"},{"key":"pone.0230194.ref073","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/MPH.0b013e31820c3b52","article-title":"Screening for psychosocial risk at pediatric cancer diagnosis: the psychosocial assessment tool","volume":"33","author":"AE Kazak","year":"2011","journal-title":"J Pediatr Hematol Oncol"},{"key":"pone.0230194.ref074","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1093\/jpepsy\/jsm031","article-title":"Evidence-based Assessment, Intervention and Psychosocial Care in Pediatric Oncology: A Blueprint for Comprehensive Services Across Treatment","volume":"32","author":"AE Kazak","year":"2007","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref075","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1093\/jpepsy\/jsy012","article-title":"Screening for Family Psychosocial Risk in Pediatric Cancer: Validation of the Psychosocial Assessment Tool (PAT) Version 3","volume":"43","author":"AE Kazak","year":"2018","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref076","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1093\/jpepsy\/jsw055","article-title":"Family Psychosocial Risk Screening in Infants and Older Children in the Acute Pediatric Hospital Setting Using the Psychosocial Assessment Tool","volume":"41","author":"MC McCarthy","year":"2016","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref077","article-title":"Assessing Psychosocial Risk in Pediatric Inflammatory Bowel Disease: Validation of the Psychosocial Assessment Tool 2.0_General","volume":"58","author":"ALH Pai","year":"2014","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"pone.0230194.ref078","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/j.1399-3046.2011.01620.x","article-title":"Psychosocial Assessment Tool 2.0_General: Validity of a psychosocial risk screener in a pediatric kidney transplant sample","volume":"16","author":"ALH Pai","year":"2012","journal-title":"Pediatric Transplantation"},{"key":"pone.0230194.ref079","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/jpepsy\/jsm053","article-title":"The Psychosocial Assessment Tool (PAT2.0): Psychometric Properties of a Screener for Psychosocial Distress in Families of Children Newly Diagnosed with Cancer","volume":"33","author":"ALH Pai","year":"2008","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref080","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/jpepsy\/jsv073","article-title":"Psychometric Properties of the Psychosocial Assessment Tool-General in Adolescents and Young Adults With Sickle Cell Disease","volume":"41","author":"LE Crosby","year":"2016","journal-title":"J Pediatr Psychol"},{"key":"pone.0230194.ref081","doi-asserted-by":"crossref","first-page":"574","DOI":"10.3109\/0284186X.2014.995774","article-title":"Family psychosocial risk screening guided by the Pediatric Psychosocial Preventative Health Model (PPPHM) using the Psychosocial Assessment Tool (PAT)","volume":"54","author":"AE Kazak","year":"2015","journal-title":"Acta Oncol"},{"key":"pone.0230194.ref082","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/978-3-319-21374-3_4","volume-title":"Pediatric Psychosocial Oncology: Textbook for Multidisciplinary Care","author":"AE Kazak","year":"2016"},{"key":"pone.0230194.ref083","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1177\/0883073817707111","article-title":"Psychometric Properties of the Psychosocial Assessment Tool\u2013Chronic Pain Version in Families of Children With Headache","volume":"32","author":"K Woods","year":"2017","journal-title":"J Child Neurol"},{"key":"pone.0230194.ref084","doi-asserted-by":"crossref","first-page":"S142","DOI":"10.1016\/j.jaac.2017.07.536","article-title":"4.5 Family-Based Psychosocial Assessment and Intervention in Pediatric Oncology","volume":"56","author":"A Kazak","year":"2017","journal-title":"Journal of the American Academy of Child & Adolescent Psychiatry"},{"key":"pone.0230194.ref085","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1093\/jpepsy\/jss087","article-title":"Examination of Risk and Resiliency in a Pediatric Sickle Cell Disease Population Using the Psychosocial Assessment Tool 2.0","volume":"37","author":"CW Karlson","year":"2012","journal-title":"Journal of Pediatric Psychology"},{"key":"pone.0230194.ref086","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1017\/S1047951113000760","article-title":"Psychosocial risk in families of infants undergoing surgery for a serious congenital heart disease","volume":"24","author":"SJ Hearps","year":"2014","journal-title":"Cardiology in the Young"},{"key":"pone.0230194.ref087","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1037\/cpp0000208","article-title":"Caregiver perspectives on family psychosocial risks and resiliencies in pediatric sickle cell disease: Informing the adaptation of the Psychosocial Assessment Tool","volume":"5","author":"SK Reader","year":"2017","journal-title":"Clinical Practice in Pediatric Psychology"},{"key":"pone.0230194.ref088","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1037\/1091-7527.24.4.381","article-title":"Pediatric Psychosocial Preventative Health Model (PPPHM): Research, practice, and collaboration in pediatric family systems medicine","volume":"24","author":"AE Kazak","year":"2006","journal-title":"Families, Systems, & Health"},{"key":"pone.0230194.ref089","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1089\/brain.2012.0127","article-title":"Disrupted Functional Brain Networks in Autistic Toddlers","volume":"3","author":"M Boersma","year":"2012","journal-title":"Brain Connectivity"},{"key":"pone.0230194.ref090","doi-asserted-by":"crossref","first-page":"e98679","DOI":"10.1371\/journal.pone.0098679","article-title":"ForceAtlas2, a Continuous Graph Layout Algorithm for Handy Network Visualization Designed for the Gephi Software","volume":"9","author":"M Jacomy","year":"2014","journal-title":"PLOS ONE"},{"key":"pone.0230194.ref091","first-page":"1129","article-title":"Graph drawing by force-directed placement","volume":"21","author":"TMJ Fruchterman","year":"1991","journal-title":"Software: Practice and Experience"},{"key":"pone.0230194.ref092","volume-title":"Network Graph Analysis and Visualization with Gephi","author":"K Cherven","year":"2013"},{"key":"pone.0230194.ref093","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/wps.20375","article-title":"A network theory of mental disorders","volume":"16","author":"D Borsboom","year":"2017","journal-title":"World Psychiatry"},{"key":"pone.0230194.ref094","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2018.01742","article-title":"Visualizing Psychological Networks: A Tutorial in R","volume":"9","author":"PJ Jones","year":"2018","journal-title":"Front Psychol"},{"key":"pone.0230194.ref095","doi-asserted-by":"crossref","first-page":"e90283","DOI":"10.1371\/journal.pone.0090283","article-title":"Towards a methodology for validation of centrality measures in complex networks","volume":"9","author":"K Batool","year":"2014","journal-title":"PLoS ONE"},{"key":"pone.0230194.ref096","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1007\/s11336-017-9557-x","article-title":"Generalized Network Psychometrics: Combining Network and Latent Variable Models","volume":"82","author":"S Epskamp","year":"2017","journal-title":"Psychometrika"},{"key":"pone.0230194.ref097","doi-asserted-by":"crossref","first-page":"195","DOI":"10.3758\/s13428-017-0862-1","article-title":"Estimating psychological networks and their accuracy: A tutorial paper","volume":"50","author":"S Epskamp","year":"2018","journal-title":"Behav Res"},{"key":"pone.0230194.ref098","doi-asserted-by":"crossref","first-page":"5918","DOI":"10.1038\/srep05918","article-title":"A new method for constructing networks from binary data","volume":"4","author":"CD van Borkulo","year":"2014","journal-title":"Scientific Reports"},{"key":"pone.0230194.ref099","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1177\/2167702615618664","article-title":"A network analysis of developmental change in ADHD symptom structure from preschool to adulthood","volume":"4","author":"MM Martel","year":"2016","journal-title":"Clin Psychol Sci"},{"key":"pone.0230194.ref100","first-page":"253","article-title":"Cancer: a family at risk","volume":"13","author":"K Wo\u017aniak","year":"2014","journal-title":"Prz Menopauzalny"},{"key":"pone.0230194.ref101","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1017\/S0140525X09991567","article-title":"Maas HLJ van der, Borsboom D. Comorbidity: A network perspective","volume":"33","author":"AOJ Cramer","year":"2010","journal-title":"Behavioral and Brain Sciences"},{"key":"pone.0230194.ref102","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.molmed.2014.10.002","article-title":"A network approach to clinical intervention in neurodegenerative diseases","volume":"20","author":"JA Santiago","year":"2014","journal-title":"Trends in Molecular Medicine"},{"key":"pone.0230194.ref103","article-title":"A network approach to the analysis of psychosocial risk factors and their association with health","author":"M Elovainio","year":"2018","journal-title":"J Health Psychol"},{"key":"pone.0230194.ref104","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1002\/eat.22890","article-title":"Social anxiety and eating disorder comorbidity and underlying vulnerabilities: Using network analysis to conceptualize comorbidity","volume":"51","author":"CA Levinson","year":"2018","journal-title":"International Journal of Eating Disorders"},{"key":"pone.0230194.ref105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cortex.2015.02.001","article-title":"Mapping the landscape of cognitive development in children with epilepsy","volume":"66","author":"TS Kellermann","year":"2015","journal-title":"Cortex"},{"key":"pone.0230194.ref106","first-page":"83","article-title":"Childhood and adolescent cancer statistics, 2014","volume":"64","author":"E Ward","year":"2014","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"pone.0230194.ref107","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1470-2045(13)70548-5","article-title":"Childhood cancer survival in Europe 1999\u20132007: results of EUROCARE-5\u2014a population-based study","volume":"15","author":"G Gatta","year":"2014","journal-title":"The Lancet Oncology"},{"key":"pone.0230194.ref108","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1002\/cncr.22107","article-title":"Psychosocial dimensions of cancer in adolescents and young adults","volume":"107","author":"EE Evan","year":"2006","journal-title":"Cancer"},{"key":"pone.0230194.ref109","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/j.jaci.2016.11.040","article-title":"Parents\u2019 childhood socioeconomic circumstances are associated with their children\u2019s asthma outcomes","volume":"140","author":"E Chen","year":"2017","journal-title":"The Journal of allergy and clinical immunology"},{"key":"pone.0230194.ref110","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/pon.4014","article-title":"Demographic, medical, and psychosocial predictors of benefit finding among caregivers of childhood cancer survivors","volume":"26","author":"MH Gardner","year":"2017","journal-title":"Psycho-Oncology"},{"key":"pone.0230194.ref111","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1177\/0883073807308712","article-title":"Parenting stress in parents of children with epilepsy and asthma","volume":"23","author":"H-H Chiou","year":"2008","journal-title":"J Child Neurol"},{"key":"pone.0230194.ref112","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s10964-016-0429-y","article-title":"The Relationship between Family Functioning and Adolescent Depressive Symptoms: The Role of Emotional Clarity","volume":"45","author":"RD Freed","year":"2016","journal-title":"J Youth Adolesc"},{"key":"pone.0230194.ref113","doi-asserted-by":"crossref","first-page":"52","DOI":"10.5127\/pr.038315","article-title":"Aetiological Influences on Stability and Change in Emotional and Behavioural Problems across Development: A Systematic Review","volume":"a4","author":"LJ Hannigan","year":"2017","journal-title":"Psychopathology Review"},{"key":"pone.0230194.ref114","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1037\/xge0000559","article-title":"Emotion Sensitivity Across the Lifespan: Mapping Clinical Risk Periods to Sensitivity to Facial Emotion Intensity","volume":"148","author":"LA Rutter","year":"2019","journal-title":"J Exp Psychol-Gen"},{"key":"pone.0230194.ref115","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1046\/j.1528-1157.2003.25002.x","article-title":"Behavioral Disorders in Pediatric Epilepsy: Unmet Psychiatric Need","volume":"44","author":"D Ott","year":"2003","journal-title":"Epilepsia"},{"key":"pone.0230194.ref116","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1007\/s10826-018-1046-z","article-title":"The Network Structure of Childhood Psychopathology in International Adoptees","volume":"27","author":"M Elovainio","year":"2018","journal-title":"Journal of Child and Family Studies"},{"key":"pone.0230194.ref117","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2018.01572","article-title":"Heterogeneity in Cognitive and Socio-Emotional Functioning in Adolescents With On-Track and Delayed School Progression","volume":"9","author":"L Vandenbroucke","year":"2018","journal-title":"Front Psychol"},{"key":"pone.0230194.ref118","doi-asserted-by":"crossref","first-page":"5153","DOI":"10.1073\/pnas.1616130114","article-title":"Brain connectivity dynamics during social interaction reflect social network structure","volume":"114","author":"R Schm\u00e4lzle","year":"2017","journal-title":"Proc Natl Acad Sci USA"},{"key":"pone.0230194.ref119","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1093\/her\/cyu040","article-title":"From controlling to letting go: what are the psychosocial needs of parents of adolescents with a chronic illness?","volume":"29","author":"C Akre","year":"2014","journal-title":"Health Educ Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0230194","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,23]],"date-time":"2020-03-23T17:30:15Z","timestamp":1584984615000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0230194"}},"subtitle":[],"editor":[{"given":"Rachel A.","family":"Annunziato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,3,23]]},"references-count":119,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0230194","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,23]]}}}