{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:25:13Z","timestamp":1791638713290,"version":"4.3.4"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T00:00:00Z","timestamp":1586390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0230708","type":"journal-article","created":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T17:28:30Z","timestamp":1586453310000},"page":"e0230708","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["Determining the predictive capability of a Clinical Assessment Scoring Chart to differentiate severity of the clinical consequences of\u00a0neonatal calf diarrhea relative to gold-standard blood gas analysis"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5377-5035","authenticated-orcid":true,"given":"Patrick","family":"Dillane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea","family":"Krump","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emer","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00edona G.","family":"Sayers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gear\u00f3id P.","family":"Sayers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,4,9]]},"reference":[{"issue":"1","key":"pone.0230708.ref001","first-page":"1","article-title":"Newborn dairy calf management","volume":"24","author":"J. Mee","year":"2008","journal-title":"Veterinary Clinics of North America: Food Animal Practice"},{"issue":"2\u20134","key":"pone.0230708.ref002","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.prevetmed.2010.12.001","article-title":"Risk factors for calf mortality in large Swedish dairy herds","volume":"99","author":"M Torsein","year":"2011","journal-title":"Preventive Veterinary Medicine"},{"issue":"3\u20134","key":"pone.0230708.ref003","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.prevetmed.2011.12.007","article-title":"Factors affecting calf mortality in Iranian Holstein dairy herds","volume":"104","author":"M Azizzadeh","year":"2012","journal-title":"Preventive Veterinary Medicine"},{"issue":"1","key":"pone.0230708.ref004","first-page":"1","article-title":"Advances in prevention and therapy of neonatal dairy calf diarrhoea: a systematical review with emphasis on colostrum management and fluid therapy","volume":"25","author":"V Meganck","year":"2014","journal-title":"Acta Veterinaria Scandinavica"},{"key":"pone.0230708.ref005","first-page":"600","article-title":"Metabolic acidosis in diarrheic neonatal calves\u2014Estimation using suckling reflex and standing ability","volume":"78","author":"T Geishauser","year":"1997","journal-title":"Prakt. Tierarzt"},{"key":"pone.0230708.ref006","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.tvjl.2003.10.021","article-title":"Investigations on the influence of serum D-lactate levels on clinical signs in calves with metabolic acidosis","volume":"168","author":"I. Lorenz","year":"2004","journal-title":"The Veterinary Journal"},{"issue":"11","key":"pone.0230708.ref007","doi-asserted-by":"crossref","first-page":"9163","DOI":"10.3168\/jds.2017-12690","article-title":"Effects of profound acidemia on the dynamic glucose and insulin response and plasma potassium and phosphorus concentrations during an intravenous glucose tolerance test in neonatal calves","volume":"100","author":"F Trefz","year":"2017","journal-title":"Journal of Dairy Science"},{"issue":"4","key":"pone.0230708.ref008","first-page":"581","article-title":"Use of a quantitative strong ion approach to determine the mechanism for acid-base abnormalities in sick calves with or without diarrhea","volume":"19","author":"P Constable","year":"2005","journal-title":"Journal of Veterinary Internal Medicine"},{"issue":"8","key":"pone.0230708.ref009","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1136\/vr.104197","article-title":"Assessing the effects of weekly preweaning health scores on dairy calf mortality and productivity parameters: cohort study","volume":"181","author":"S Mahendran","year":"2017","journal-title":"Veterinary Record"},{"issue":"9","key":"pone.0230708.ref010","first-page":"1","article-title":"Calf health from birth to weaning. II. Management of diarrhoea in pre-weaned calves","volume":"64","author":"I Lorenz","year":"2011","journal-title":"The Irish Veterinary Journal"},{"issue":"1","key":"pone.0230708.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4142\/jvs.2014.15.1.1","article-title":"An overview of calf diarrhea\u2014infectious etiology, diagnosis, and intervention","volume":"15","author":"Y Cho","year":"2014","journal-title":"Journal of Veterinary Science"},{"issue":"6","key":"pone.0230708.ref012","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.3168\/jds.2015-10600","article-title":"An observational study using blood gas analysis to assess neonatal calf diarrhoea and subsequent recovery with a European Commission-compliant oral electrolyte solution","volume":"99","author":"RG Sayers","year":"2016","journal-title":"Journal of Dairy Science"},{"issue":"20","key":"pone.0230708.ref013","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1136\/vr.161.20.688","article-title":"Blood gas and acid-base analysis of arterial blood in 57 newborn calves","volume":"161","author":"U Bleul","year":"2007","journal-title":"The Veterinary Record"},{"issue":"3","key":"pone.0230708.ref014","first-page":"403","article-title":"Evaluation of the ruminant serum chemistry profile","volume":"23","author":"KE Russell","year":"2007","journal-title":"Veterinary Clinics of North America: Food Animal Practice"},{"issue":"2","key":"pone.0230708.ref015","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0195-5616(89)50032-9","article-title":"Mixed acid-base disorders","volume":"19","author":"LG Adams","year":"1989","journal-title":"Veterinary Clinics of North America: Food Animal Practice"},{"issue":"13","key":"pone.0230708.ref016","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1136\/vr.156.13.412","article-title":"Investigations of D-lactate metabolism and the clinical signs of D-lactataemia in calves","volume":"156","author":"I Lorenz","year":"2005","journal-title":"Veterinary Record"},{"issue":"8","key":"pone.0230708.ref017","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182938","article-title":"Clinical signs, profound acidemia, hypoglycaemia, and hypernatremia are predictive of mortality in 1,400 ill neonatal calves with diarrhea","volume":"12","author":"FM Trefz","year":"2017","journal-title":"Plos One"},{"issue":"7","key":"pone.0230708.ref018","first-page":"577","article-title":"A retrospective study of the relationship between clinical signs and severity of acidosis in diarrheic calves","volume":"30","author":"J. Naylor","year":"1989","journal-title":"Canadian Veterinary Journal"},{"key":"pone.0230708.ref019","article-title":"Heifer raising\u2014birth to weaning","author":"MA Wattiaux","year":"2005","journal-title":"Neonatal diarrhoea"},{"issue":"5","key":"pone.0230708.ref020","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1292\/jvms.69.549","article-title":"Relationship between depression score and acid-base status in Japanese Black calves with diarrhea","volume":"69","author":"M Nakagawa","year":"2007","journal-title":"Journal of Veterinary Medical Science"},{"issue":"8","key":"pone.0230708.ref021","first-page":"1","article-title":"Construction and validation of a decision tree for treating metabolic acidosis in calves with neonatal diarrhea","volume":"6","author":"F Trefz","year":"2012","journal-title":"BMC Veterinary Research"},{"key":"pone.0230708.ref022","first-page":"340","volume-title":"Large Animal Internal Medicine","author":"BP Smith","year":"2009"},{"key":"pone.0230708.ref023","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3168\/jds.S0022-0302(89)79081-0","article-title":"A Body Condition Scoring Chart for Holstein Dairy Cows","volume":"72","author":"A Edmonson","year":"1989","journal-title":"Journal of Dairy Science"},{"issue":"1","key":"pone.0230708.ref024","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3168\/jds.2007-0496","article-title":"Evaluation of a lameness scoring system for dairy cows","volume":"91","author":"P Thomsen","year":"2008","journal-title":"Journal of Dairy Science"},{"issue":"3\u20134","key":"pone.0230708.ref025","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.prevetmed.2015.02.018","article-title":"Bayesian estimation of the accuracy of the calf respiratory scoring chart and ultrasonography for the diagnosis of bovine respiratory disease in pre-weaned dairy calves","volume":"119","author":"S Buczinski","year":"2015","journal-title":"Preventive Veterinary Medicine"},{"issue":"2","key":"pone.0230708.ref026","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0034-5288(18)33148-5","article-title":"Evaluation of respiratory disease in calves: comparison of disease response to different viruses","volume":"23","author":"L Thomas","year":"1977","journal-title":"Research in Veterinary Science"},{"issue":"1","key":"pone.0230708.ref027","first-page":"139","article-title":"Disease management of dairy calves and heifers","volume":"24","author":"S. McGuirk","year":"2008","journal-title":"Veterinary Clinics of North America: Food Animal Practice"},{"issue":"2","key":"pone.0230708.ref028","first-page":"191","article-title":"Pathogenesis and pathology of bovine pneumonia","volume":"26","author":"R Panciera","year":"2010","journal-title":"Veterinary Clinics of North America: Food Animal Practice"},{"issue":"10","key":"pone.0230708.ref029","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1002\/sim.1742","article-title":"Presentation of multivariate data for clinical use: the Framingham Study risk score functions","volume":"23","author":"L Sullivan","year":"2004","journal-title":"Statistics in Medicine"},{"key":"pone.0230708.ref030","article-title":"Development of a novel clinical scoring system for on-farm diagnosis of bovine respiratory disease in pre-weaned dairy calves","author":"W Love","year":"2014","journal-title":"PeerJ"},{"issue":"10","key":"pone.0230708.ref031","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.3168\/jds.S0022-0302(95)76857-6","article-title":"Validation of body condition scores with ultrasound measurements of subcutaneous fat of dairy cows","volume":"78","author":"J Domecq","year":"1995","journal-title":"Journal of Dairy Science"},{"issue":"4","key":"pone.0230708.ref032","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.3168\/jds.2017-13445","article-title":"Establishing blood gas ranges in healthy bovine neonates differentiated by age, sex, and breed type","volume":"101","author":"P Dillane","year":"2018","journal-title":"Journal of Dairy Science"},{"key":"pone.0230708.ref033","volume-title":"An Illustrated Guide to Veterinary Medical Terminology","author":"JA Romich","year":"2009"},{"issue":"1","key":"pone.0230708.ref034","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.tvjl.2012.11.002","article-title":"Hyperkalemia in diarrheic calves: Implications for diagnosis and treatment","volume":"3","author":"PD Constable","year":"2013","journal-title":"The Veterinary Journal"},{"issue":"2","key":"pone.0230708.ref035","first-page":"409","article-title":"Fluid therapy in calves","volume":"30","author":"GW Smith","year":"2014","journal-title":"Veterinary Clinics of North America: Food Animal Practice"},{"issue":"5","key":"pone.0230708.ref036","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.3168\/jds.2013-6803","article-title":"Identification of predictive biomarkers of disease state in transition dairy cows","volume":"97","author":"D Hailemariam","year":"2014","journal-title":"Journal of Dairy Science"},{"issue":"2","key":"pone.0230708.ref037","first-page":"1","article-title":"Relationship between the values of blood parameters and physical status in Korean calves with diarrhea","volume":"21","author":"SH Lee","year":"2020","journal-title":"Journal of Veterinary Science"},{"issue":"1","key":"pone.0230708.ref038","first-page":"45","article-title":"Evaluation of the total carbon dioxide apparatus and pH meter for the determination of acid-base status in diarrheic and healthy calves","volume":"48","author":"J. Naylor","year":"1987","journal-title":"Canadian Veterinary Journal"},{"issue":"12","key":"pone.0230708.ref039","doi-asserted-by":"crossref","first-page":"e114391","DOI":"10.1371\/journal.pone.0114391","article-title":"Systematic Classification of Disease Severity for Evaluation of Expanded Carrier Screening Panels","volume":"9","author":"G Lazarin","year":"2014","journal-title":"Plos One"},{"issue":"11","key":"pone.0230708.ref040","doi-asserted-by":"crossref","first-page":"7234","DOI":"10.3168\/jds.2013-6945","article-title":"Hyperkalemia in neonatal diarrheic calves depends on the degree of dehydration and the cause of the metabolic acidosis but does not require the presence of acidemia","volume":"96","author":"FM Trefz","year":"2013","journal-title":"Journal of Dairy Science"},{"issue":"2","key":"pone.0230708.ref041","first-page":"295","article-title":"Acid-base assessment: when and how to apply the Henderson-Hasselbalch equation and strong ion difference theory","volume":"30","author":"PD Constable","year":"2014","journal-title":"Veterinary Clinics of North America: Food Animal Practice"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0230708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T17:28:44Z","timestamp":1586453324000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0230708"}},"subtitle":[],"editor":[{"given":"Angel","family":"Abuelo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,4,9]]},"references-count":41,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,4,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0230708","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,9]]}}}