{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T16:02:32Z","timestamp":1772208152982,"version":"3.50.1"},"reference-count":81,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T00:00:00Z","timestamp":1617926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The present study aims to extend the knowledge of the neural correlates of emotion processing in first episode subjects affected by anorexia nervosa (AN) or bulimia nervosa (BN). We applied an emotional distress paradigm targeting negative emotions thought to be relevant for interpersonal difficulties and therapeutic resistance mechanisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The current study applied to 44 female participants with newly diagnosed AN or BN and 20 matched controls a neuroimaging paradigm eliciting affective responses. The measurements also included an extensive assessment comprising clinical scales, neuropsychological tests, measures of emotion processing and empathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AN and BN did not differ from controls in terms of emotional response, emotion matching, self-reported empathy and cognitive performance. However, eating disorder and psychopathological clinical scores, as well as alexithymia levels, were increased in AN and BN. On a neural level, no significant group differences emerged, even when focusing on a region of interest selected a priori: the amygdala. Some interesting findings put in relation the hippocampal activity with the level of Body Dissatisfaction of the participants, the relative importance of the key nodes for the common network in the decoding of different emotions (BN = right amygdala, AN = anterior cingulate area), and the qualitative profile of the deactivations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our data do not support the hypothesis that participants with AN or BN display reduced emotional responsiveness. However, peculiar characteristics in emotion processing could be associated to the three different groups. Therefore, relational difficulties in eating disorders, as well as therapeutic resistance, could be not secondary to a simple difficulty in feeling and identifying basic negative emotions in AN and BN participants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0231684","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T13:22:05Z","timestamp":1617974525000},"page":"e0231684","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Emotional imagination of negative situations: Functional neuroimaging in anorexia and bulimia"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-0248","authenticated-orcid":true,"given":"Federico","family":"D\u2019Agata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Caroppo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Spalatro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Lavagnino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Abbate Daga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Boghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Bergui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Cicerale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedetto","family":"Vitiello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Secondo","family":"Fassino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Derntl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Amianto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,4,9]]},"reference":[{"issue":"9912","key":"pone.0231684.ref001","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0140-6736(13)61746-8","article-title":"Focal 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Aggleton","year":"2000","edition":"2"},{"issue":"4","key":"pone.0231684.ref032","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.neubiorev.2007.12.002","article-title":"The role of the amygdala in emotional processing: A quantitative meta-analysis of functional neuroimaging studies","volume":"32","author":"K Sergerie","year":"2008","journal-title":"Neuroscience and Biobehavioral Reviews"},{"issue":"20","key":"pone.0231684.ref033","doi-asserted-by":"crossref","first-page":"9400","DOI":"10.1073\/pnas.1000985107","article-title":"Different amygdala subregions mediate valence-related and attentional effects of oxytocin in humans","volume":"107","author":"M Gamer","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5\u20136","key":"pone.0231684.ref034","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s00429-005-0025-5","article-title":"Cytoarchitectonic mapping of the human amygdala, hippocampal region and entorhinal cortex: intersubject variability and probability maps","volume":"210","author":"K Amunts","year":"2005","journal-title":"Anat Embryol"},{"issue":"1","key":"pone.0231684.ref035","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.neuro.23.1.155","article-title":"Emotion Circuits in the Brain","volume":"23","author":"JE LeDoux","year":"2000","journal-title":"Annu Rev Neurosci"},{"issue":"3","key":"pone.0231684.ref036","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.neubiorev.2010.10.009","article-title":"Is there a core neural network in empathy? 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Item selection and cross-validation of the factor structure","volume":"38","author":"RM Bagby","year":"1994","journal-title":"Journal of Psychosomatic Research"},{"issue":"1\u20133","key":"pone.0231684.ref044","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.schres.2008.11.009","article-title":"Generalized deficit in all core components of empathy in schizophrenia","volume":"108","author":"B Derntl","year":"2009","journal-title":"Schizophrenia Research"},{"issue":"4","key":"pone.0231684.ref045","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1006\/nimg.2001.1037","article-title":"Thresholding of statistical maps in functional neuroimaging using the false discovery rate","volume":"15","author":"CR Genovese","year":"2002","journal-title":"NeuroImage"},{"issue":"243","key":"pone.0231684.ref046","article-title":"Influences of Head Motion Regression on High-Frequency Oscillation Amplitudes of Resting-State fMRI Signals","volume":"10","author":"B-K Yuan","year":"2016","journal-title":"Frontiers in Human Neuroscience"},{"issue":"3","key":"pone.0231684.ref047","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.pscychresns.2010.12.008","article-title":"In vivo evidence of global and focal brain alterations in anorexia nervosa","volume":"192","author":"A Boghi","year":"2011","journal-title":"Psychiatry Research"},{"issue":"6","key":"pone.0231684.ref048","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.3174\/ajnr.A2935","article-title":"Automatic voxel-based morphometry of structural MRI by SPM8 plus diffeomorphic anatomic registration through exponentiated lie algebra improves the diagnosis of probable Alzheimer Disease","volume":"33","author":"H Matsuda","year":"2012","journal-title":"American Journal of Neuroradiology"},{"key":"pone.0231684.ref049","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3389\/fninf.2014.00088","article-title":"The Decoding Toolbox (TDT): a versatile software package for multivariate analyses of functional imaging data","volume":"8","author":"MN Hebart","year":"2015","journal-title":"Front Neuroinform"},{"key":"pone.0231684.ref050","unstructured":"Rodr\u00edguez-Avi J, Ariza-L\u00f3pez FJ, Alba-Fern\u00e1ndez MaV. Methods for comparing two observed confusion matrices. 21st AGILE Conference on Geographic Information Science. Lund University 12\u201315 June 2018, Lund, Sweden. ISBN 978-3-319-78208-9."},{"issue":"11","key":"pone.0231684.ref051","first-page":"1421","article-title":"Topographic organization of the human subcortex unveiled with functional connectivity gradients","volume":"23","author":"Y Tian","year":"2020","journal-title":"Neuroscience"},{"issue":"318","key":"pone.0231684.ref052","first-page":"626","article-title":"Rectangular Confidence Regions for the Means of Multivariate Normal Distributions","volume":"62","author":"Z Sidak","year":"1967","journal-title":"Journal of the American Statistical Association"},{"issue":"1","key":"pone.0231684.ref053","doi-asserted-by":"crossref","first-page":"180063","DOI":"10.1038\/sdata.2018.63","article-title":"A high-resolution probabilistic in vivo atlas of human subcortical brain nuclei","volume":"5","author":"WM Pauli","year":"2018","journal-title":"Sci Data"},{"issue":"2","key":"pone.0231684.ref054","first-page":"e73","article-title":"Affective style and eating disorders: A field study","volume":"16","author":"JR Silva","year":"2011","journal-title":"Eating and Weight Disorders\u2014Studies on Anorexia, Bulimia and Obesity"},{"issue":"5","key":"pone.0231684.ref055","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.comppsych.2014.02.009","article-title":"The role of temperament and character in the outcome of depressive mood in eating disorders","volume":"55","author":"T Rodr\u00edguez-Cano","year":"2014","journal-title":"Comprehensive Psychiatry"},{"issue":"6","key":"pone.0231684.ref056","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3109\/15622975.2011.639804","article-title":"Is attention to detail a similarly strong candidate endophenotype for anorexia nervosa and bulimia nervosa?","volume":"14","author":"ME Roberts","year":"2013","journal-title":"The World Journal of Biological Psychiatry"},{"issue":"6","key":"pone.0231684.ref057","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1002\/erv.2199","article-title":"Emotions in eating disorders: changes of anger control after an emotion-focused day hospital treatment","volume":"20","author":"G Abbate-Daga","year":"2012","journal-title":"European Eating Disorders Review"},{"issue":"6","key":"pone.0231684.ref058","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/cpp.726","article-title":"Experimental measurement of the regulation of anger and aggression in women with anorexia nervosa","volume":"18","author":"A Harrison","year":"2011","journal-title":"Clin Psychol Psychother"},{"issue":"2","key":"pone.0231684.ref059","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/eat.20929","article-title":"Heightened fear of uncertainty in anorexia and bulimia nervosa","volume":"45","author":"GKW Frank","year":"2012","journal-title":"Int J Eat Disord"},{"issue":"4","key":"pone.0231684.ref060","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/1097-4679(199207)48:4<472::AID-JCLP2270480407>3.0.CO;2-#","article-title":"Bulimia and fear of intimacy","volume":"48","author":"JA Pruitt","year":"1992","journal-title":"J Clin Psychol"},{"issue":"12","key":"pone.0231684.ref061","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1002\/eat.22789","article-title":"Doubt and fear of self in bulimia nervosa","volume":"50","author":"S Wilson","year":"2017","journal-title":"Int J Eat Disord"},{"key":"pone.0231684.ref062","doi-asserted-by":"crossref","first-page":"346","DOI":"10.3389\/fnhum.2018.00346","article-title":"Is Our Self Related to Personality? 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