{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:21:54Z","timestamp":1789471314370,"version":"build-2803163510"},"reference-count":58,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T00:00:00Z","timestamp":1587686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The author(s) received no specific funding for this work."}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0231816","type":"journal-article","created":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T17:32:35Z","timestamp":1587749555000},"page":"e0231816","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Association of early viral lower respiratory infections and subsequent development of atopy, a systematic review and meta-analysis of cohort studies"],"prefix":"10.1371","volume":"15","author":[{"given":"Sebastien","family":"Kenmoe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyprien","family":"Kengne-Nde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdou Fatawou","family":"Modiyinji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Joel","family":"Bigna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3112-6370","authenticated-orcid":true,"given":"Richard","family":"Njouom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,4,24]]},"reference":[{"key":"pone.0231816.ref001","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1056\/NEJM200101043440106","article-title":"Allergy and allergic diseases. First of two parts","volume":"344","author":"AB Kay","year":"2001","journal-title":"N Engl J Med"},{"key":"pone.0231816.ref002","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S1081-1206(10)62426-X","article-title":"T-cell subsets (Th1 versus Th2)","volume":"85","author":"S. Romagnani","year":"2000","journal-title":"Ann Allergy Asthma Immunol"},{"key":"pone.0231816.ref003","article-title":"Economic Burden of Adult Patients with Moderate to Severe Atopic Dermatitis Indicated for Systemic Treatment.","author":"LFM Ari\u00ebns","year":"2019","journal-title":"Acta Derm Venereol."},{"key":"pone.0231816.ref004","doi-asserted-by":"crossref","first-page":"e39803","DOI":"10.1371\/journal.pone.0039803","article-title":"Investigating international time trends in the incidence and prevalence of atopic eczema 1990\u20132010: a systematic review of epidemiological studies.","volume":"7","author":"IAG Deckers","year":"2012","journal-title":"PLoS ONE"},{"key":"pone.0231816.ref005","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1111\/j.1399-3038.2007.00554.x","article-title":"The changing prevalence of asthma, allergic rhinitis and atopic eczema in African adolescents from 1995 to 2002","volume":"18","author":"HJ Zar","year":"2007","journal-title":"Pediatr Allergy Immunol"},{"key":"pone.0231816.ref006","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1164\/rccm.201807-1333OC","article-title":"Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi","volume":"200","author":"SJ Aston","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"pone.0231816.ref007","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/jmv.25347","article-title":"Demographic and seasonal characteristics of respiratory pathogens in neonates and infants aged 0 to 12 months in the Central\u2010East region of Tunisia","volume":"91","author":"I Brini Khalifa","year":"2019","journal-title":"J Med Virol"},{"key":"pone.0231816.ref008","article-title":"Association Between Respiratory Syncytial Virus-Associated Acute Lower Respiratory Infection in Early Life and Recurrent Wheeze and Asthma in Later Childhood","author":"T Shi","year":"2019","journal-title":"J Infect Dis"},{"key":"pone.0231816.ref009","article-title":"Association between Respiratory Syncytial Virus Hospitalizations in Infants and Respiratory Sequelae: Systematic Review and Meta-Analysis","volume":"1","author":"S R\u00e9gnier","year":"2013","journal-title":"The Pediatric Infectious Disease Journal"},{"key":"pone.0231816.ref010","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1111\/j.1651-2227.2000.tb00359.x","article-title":"Long-term effects of respiratory syncytial virus (RSV) bronchiolitis in infants and young children: a quantitative review.","volume":"89","author":"MCJ Kneyber","year":"2000","journal-title":"Acta Paediatrica"},{"key":"pone.0231816.ref011","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/INF.0b013e3180618c42","article-title":"The association between respiratory syncytial virus infection and the development of childhood asthma: a systematic review of the literature","volume":"26","author":"EG P\u00e9rez-Yarza","year":"2007","journal-title":"Pediatr Infect Dis J"},{"key":"pone.0231816.ref012","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0031239","article-title":"Long Term Sequelae from Childhood Pneumonia; Systematic Review and Meta-Analysis.","volume":"7","author":"K Edmond","year":"2012","journal-title":"PLoS One."},{"key":"pone.0231816.ref013","doi-asserted-by":"crossref","first-page":"e013034","DOI":"10.1136\/bmjopen-2016-013034","article-title":"Association between rhinovirus wheezing illness and the development of childhood asthma: a meta-analysis","volume":"7","author":"L Liu","year":"2017","journal-title":"BMJ Open"},{"key":"pone.0231816.ref014","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/02770908709073188","article-title":"Allergic predisposition among infants with bronchiolitis.","volume":"24","author":"Y Nagayama","year":"1987","journal-title":"J Asthma"},{"key":"pone.0231816.ref015","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/ppul.1950030308","article-title":"Acute bronchiolitis: predisposing factors and characterization of infants at risk.","volume":"3","author":"KH Carlsen","year":"1987","journal-title":"Pediatric pulmonology."},{"key":"pone.0231816.ref016","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/j.1399-3038.1997.tb00145.x","article-title":"Atopic versus infectious diseases in childhood: a question of balance?","volume":"8","author":"PG Holt","year":"1997","journal-title":"Pediatr Allergy Immunol"},{"key":"pone.0231816.ref017","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0091-6749(71)90029-7","article-title":"Patterns of allergic respiratory disease in children with a past history of bronchiolitis","volume":"48","author":"B Zweiman","year":"1971","journal-title":"J Allergy Clin Immunol"},{"key":"pone.0231816.ref018","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/S0140-6736(98)10321-5","article-title":"Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years","volume":"354","author":"RT Stein","year":"1999","journal-title":"Lancet"},{"key":"pone.0231816.ref019","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1136\/adc.59.4.299","article-title":"Symptoms, atopy, and bronchial reactivity after lower respiratory infection in infancy","volume":"59","author":"JY Mok","year":"1984","journal-title":"Arch Dis Child"},{"key":"pone.0231816.ref020","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1542\/peds.2013-0982","article-title":"Effect of palivizumab prophylaxis on subsequent recurrent wheezing in preterm infants","volume":"132","author":"S Yoshihara","year":"2013","journal-title":"Pediatrics"},{"key":"pone.0231816.ref021","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1378\/chest.122.3.935","article-title":"Early ribavarin treatment of bronchiolitis: effect on long-term respiratory morbidity.","volume":"122","author":"D Edell","year":"2002","journal-title":"Chest"},{"key":"pone.0231816.ref022","doi-asserted-by":"crossref","first-page":"183","DOI":"10.2174\/157339811795589496","article-title":"Interventions to Prevent Long-Term Consequences of Bronchiolitis.","volume":"7","author":"A Mejias","year":"2011","journal-title":"CRMR"},{"key":"pone.0231816.ref023","volume-title":"CRD\u2019s guidance for undertaking reviews in 301 healthcare: centers for reviews and dissemination","author":"Centers for Reviews and Dissemination","year":"2009"},{"key":"pone.0231816.ref024","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement.","volume":"6","author":"D Moher","year":"2009","journal-title":"PLoS Med."},{"key":"pone.0231816.ref025","doi-asserted-by":"crossref","DOI":"10.1186\/s13643-016-0384-4","article-title":"Rayyan\u2014a web and mobile app for systematic reviews.","volume":"5","author":"M Ouzzani","year":"2016","journal-title":"Syst Rev."},{"key":"pone.0231816.ref026","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.jclinepi.2011.11.014","article-title":"Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement.","volume":"65","author":"D Hoy","year":"2012","journal-title":"J Clin Epidemiol."},{"key":"pone.0231816.ref027","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis.","volume":"21","author":"JPT Higgins","year":"2002","journal-title":"Stat Med"},{"key":"pone.0231816.ref028","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2307\/3001666","article-title":"The Combination of Estimates from Different Experiments","volume":"10","author":"WG Cochran","year":"1954","journal-title":"Biometrics"},{"key":"pone.0231816.ref029","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1471-2431-5-31","article-title":"Acute bronchiolitis in infancy as risk factor for wheezing and reduced pulmonary function by seven years in Akershus County, Norway","volume":"5","author":"H-O Fj\u00e6rli","year":"2005","journal-title":"BMC Pediatr"},{"key":"pone.0231816.ref030","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/ppul.20597","article-title":"Human metapneumovirus bronchiolitis in infancy is an important risk factor for asthma at age 5.","volume":"42","author":"ML Garc\u00eda-Garc\u00eda","year":"2007","journal-title":"Pediatr Pulmonol"},{"key":"pone.0231816.ref031","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1399-3038.2005.00298.x","article-title":"Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma, atopy and wheeze: a longitudinal birth cohort study","volume":"16","author":"J Henderson","year":"2005","journal-title":"Pediatr Allergy Immunol"},{"key":"pone.0231816.ref032","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1034\/j.1398-9995.2003.00233.x","article-title":"Association of an early respiratory syncytial virus infection and atopic allergy","volume":"58","author":"H Juntti","year":"2003","journal-title":"Allergy"},{"key":"pone.0231816.ref033","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ppul.20058","article-title":"Respiratory morbidity 20 years after RSV infection in infancy.","volume":"38","author":"M Korppi","year":"2004","journal-title":"Pediatr Pulmonol"},{"key":"pone.0231816.ref034","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1136\/adc.67.4.482","article-title":"Respiratory status and allergy after bronchiolitis","volume":"67","author":"M Murray","year":"1992","journal-title":"Archives of Disease in Childhood"},{"key":"pone.0231816.ref035","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/INF.0000000000001385","article-title":"Risk Factors for Virus-induced Acute Respiratory Tract Infections in Children Younger Than 3 Years and Recurrent Wheezing at 36 Months Follow-Up After Discharge","volume":"36","author":"A Nicolai","year":"2017","journal-title":"The Pediatric Infectious Disease Journal"},{"key":"pone.0231816.ref036","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1089\/ped.2011.0127","article-title":"Exhaled Nitric Oxide in Acute Phase of Bronchiolitis and Its Relation with Episodes of Subsequent Wheezing in Children of Preschool Age","volume":"25","author":"JA Pe\u00f1a Zarza","year":"2012","journal-title":"Pediatr Allergy Immunol Pulmonol"},{"key":"pone.0231816.ref037","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1378\/chest.10-0365","article-title":"Causal direction between respiratory syncytial virus bronchiolitis and asthma studied in monozygotic twins.","volume":"138","author":"P Poorisrisak","year":"2010","journal-title":"Chest"},{"key":"pone.0231816.ref038","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1097\/01.inf.0000243214.80794.3a","article-title":"Long-term consequences of respiratory syncytial virus acute lower respiratory tract infection in early childhood in Guinea-bissau.","volume":"25","author":"A Poulsen","year":"2006","journal-title":"Pediatr Infect Dis J"},{"key":"pone.0231816.ref039","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1136\/bmj.284.6330.1665","article-title":"Wheezing, asthma, and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy.","volume":"284","author":"CR Pullan","year":"1982","journal-title":"Br Med J (Clin Res Ed)."},{"key":"pone.0231816.ref040","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/ppul.22692","article-title":"Adolescent asthma after rhinovirus and respiratory syncytial virus bronchiolitis.","volume":"48","author":"M Ruotsalainen","year":"2013","journal-title":"Pediatric Pulmonology"},{"key":"pone.0231816.ref041","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1183\/09031936.02.00019902","article-title":"RSV bronchiolitis and risk of wheeze and allergic sensitisation in the first year of life","volume":"20","author":"U Schauer","year":"2002","journal-title":"Eur Respir J"},{"key":"pone.0231816.ref042","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1542\/peds.95.4.500","article-title":"Asthma and immunoglobulin E antibodies after respiratory syncytial virus bronchiolitis: a prospective cohort study with matched controls","volume":"95","author":"N Sigurs","year":"1995","journal-title":"Pediatrics"},{"key":"pone.0231816.ref043","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1164\/ajrccm.161.5.9906076","article-title":"Respiratory Syncytial Virus Bronchiolitis in Infancy Is an Important Risk Factor for Asthma and Allergy at Age 7","volume":"161","author":"N Sigurs","year":"2000","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"pone.0231816.ref044","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1164\/rccm.200406-730OC","article-title":"Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13","volume":"171","author":"N Sigurs","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"pone.0231816.ref045","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1136\/thx.2009.121582","article-title":"Asthma and allergy patterns over 18 years after severe RSV bronchiolitis in the first year of life.","volume":"65","author":"N Sigurs","year":"2010","journal-title":"Thorax"},{"key":"pone.0231816.ref046","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1136\/bmj.282.6282.2086","article-title":"Atopy does not predispose to RSV bronchiolitis or postbronchiolitic wheezing","volume":"282","author":"DG Sims","year":"1981","journal-title":"Br Med J (Clin Res Ed)."},{"key":"pone.0231816.ref047","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1136\/adc.59.10.935","article-title":"Factors predisposing to abnormal pulmonary function after adenovirus type 7 pneumonia","volume":"59","author":"PD Sly","year":"1984","journal-title":"Arch Dis Child"},{"key":"pone.0231816.ref048","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1399-3038.1997.tb00134.x","article-title":"Association between pronounced IgA response in RSV bronchiolitis and development of allergic sensitization","volume":"8","author":"O Stranneg\u00e5rd","year":"1997","journal-title":"Pediatr Allergy Immunol"},{"key":"pone.0231816.ref049","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1097\/INF.0b013e3181dea5de","article-title":"Respiratory morbidity in adulthood after respiratory syncytial virus hospitalization in infancy.","volume":"29","author":"M Ruotsalainen","year":"2010","journal-title":"Pediatr Infect Dis J"},{"key":"pone.0231816.ref050","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1399-3038.2012.01283.x","article-title":"The outcome after severe bronchiolitis is related to gender and virus","volume":"23","author":"IB Mikalsen","year":"2012","journal-title":"Pediatr Allergy Immunol"},{"key":"pone.0231816.ref051","first-page":"228","article-title":"Development of allergy in children. I. Association with virus infections","volume":"63","author":"OL Frick","year":"1979","journal-title":"J Allergy Clin Immunol"},{"key":"pone.0231816.ref052","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.anai.2013.03.006","article-title":"Discordance between Aeroallergen Specific Serum IgE and Skin Testing in Children < 4 years of age","volume":"110","author":"G de Vos","year":"2013","journal-title":"Ann Allergy Asthma Immunol"},{"key":"pone.0231816.ref053","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1046\/j.1365-2222.1998.00339.x","article-title":"Comparison of skin-prick test and specific serum IgE determination for the diagnosis of latex allergy","volume":"28","author":"C Blanco","year":"1998","journal-title":"Clin Exp Allergy"},{"key":"pone.0231816.ref054","doi-asserted-by":"crossref","first-page":"386","DOI":"10.2500\/aap.2009.30.3258","article-title":"Comparison of serum-specific IgE (ImmunoCAP) and skin-prick test results for 53 inhalant allergens in patients with chronic rhinitis.","volume":"30","author":"CW Calabria","year":"2009","journal-title":"Allergy Asthma Proc"},{"key":"pone.0231816.ref055","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1111\/j.1365-2222.2012.04046.x","article-title":"Skin prick test and specific serum IgE in the diagnostic evaluation of suspected cow\u2019s milk and hen\u2019s egg allergy in children: does one replace the other?","volume":"42","author":"A Mehl","year":"2012","journal-title":"Clin Exp Allergy"},{"issue":"Suppl 86","key":"pone.0231816.ref056","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","article-title":"Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen).","volume":"63","author":"J Bousquet","year":"2008","journal-title":"Allergy"},{"key":"pone.0231816.ref057","doi-asserted-by":"crossref","first-page":"198","DOI":"10.2500\/aap.2011.32.3441","article-title":"Comparison of the Multi-Test II and ComforTen allergy skin test devices","volume":"32","author":"MS Dykewicz","year":"2011","journal-title":"Allergy Asthma Proc"},{"key":"pone.0231816.ref058","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s40121-017-0151-4","article-title":"The Burden and Long-term Respiratory Morbidity Associated with Respiratory Syncytial Virus Infection in Early Childhood.","volume":"6","author":"B Fauroux","year":"2017","journal-title":"Infect Dis Ther."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0231816","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,22]],"date-time":"2022-10-22T07:21:34Z","timestamp":1666423294000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0231816"}},"subtitle":[],"editor":[{"given":"Renee W.Y.","family":"Chan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,4,24]]},"references-count":58,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,4,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0231816","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,24]]}}}