{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:10:43Z","timestamp":1790367043491,"version":"4.1.0"},"reference-count":72,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0233670","type":"journal-article","created":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T13:34:15Z","timestamp":1591191255000},"page":"e0233670","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":21,"title":["Reduced hippocampal volume in adolescents with psychotic experiences: A longitudinal population-based study"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7953-2629","authenticated-orcid":true,"given":"Ana","family":"Calvo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren W.","family":"Roddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Coughlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Kelleher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colm","family":"Healy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Harley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Leemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Frodl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"O\u2019Hanlon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Cannon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,6,3]]},"reference":[{"key":"pone.0233670.ref001","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/7854_2010_43","article-title":"Hippocampal pathology in schizophrenia","volume":"4","author":"S Heckers","year":"2010","journal-title":"Curr Top Behav Neurosci"},{"issue":"4","key":"pone.0233670.ref002","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/mp.2015.118","article-title":"Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium","volume":"21","author":"TG van Erp","year":"2016","journal-title":"Mol Psychiatry"},{"issue":"11","key":"pone.0233670.ref003","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1001\/jamapsychiatry.2017.2663","article-title":"Heterogeneity and Homogeneity of Regional Brain Structure in Schizophrenia: A Meta-analysis","volume":"74","author":"SP Brugger","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"pone.0233670.ref004","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1176\/ajp.157.1.16","article-title":"Meta-analysis of regional brain volumes in schizophrenia","volume":"157","author":"IC Wright","year":"2000","journal-title":"Am J Psychiatry"},{"issue":"2\u20133","key":"pone.0233670.ref005","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.schres.2014.10.041","article-title":"Brain structure in people at ultra-high risk of psychosis, patients with first-episode schizophrenia, and healthy contorls: a VBM study","volume":"161","author":"I Nenadic","year":"2015","journal-title":"Schizophr Res"},{"key":"pone.0233670.ref006","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nrn2335","article-title":"The hippocampus and memory: insights from apatial processing","volume":"9","author":"C Bird","year":"2008","journal-title":"Nat Rev Neurosci"},{"key":"pone.0233670.ref007","doi-asserted-by":"crossref","first-page":"2470547019849376","DOI":"10.1177\/2470547019849376","article-title":"Cornu Ammonis Changes Are at the Core of Hippocampal Pathology in Depression","volume":"3","author":"D Roddy","year":"2019","journal-title":"Chronic Stress"},{"key":"pone.0233670.ref008","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3389\/fnana.2019.00014","article-title":"Papez\u2019s forgotten tract: 80 years of unreconciled findings concerning the thalamocingulate tract","volume":"13","author":"JK Weininger","year":"2019","journal-title":"Frontiers in neuroanatomy"},{"issue":"7","key":"pone.0233670.ref009","doi-asserted-by":"crossref","first-page":"e859","DOI":"10.1038\/tp.2016.117","article-title":"Impaired fornix-hippocampus integrity is linked to peripheral glutathione peroxidase in early psychosis","volume":"6","author":"PS Baumann","year":"2016","journal-title":"Transl Psychiatry"},{"key":"pone.0233670.ref010","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3389\/fnbeh.2019.00098","article-title":"Distinct Time-Course of Alterations of Groups I and II Metabotropic Glutamate Receptor and GABAergic Receptor Expression Along the Dorsoventral Hippocampal Axis in an Animal Model of Psychosis","volume":"13","author":"V Dubovyk","year":"2019","journal-title":"Front Behav Neurosci"},{"issue":"4","key":"pone.0233670.ref011","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1176\/appi.ajp.2015.15040485","article-title":"Resting Hyperperfusion of the Hippocampus, Midbrain, and Basal Ganglia in People at High Risk for Psychosis","volume":"173","author":"P Allen","year":"2016","journal-title":"Am J Psychiatry"},{"issue":"1","key":"pone.0233670.ref012","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.neuroimage.2010.04.012","article-title":"Hippocampal pathology in individuals at ultra-high risk for psychosis: a multi-modal magnetic resonance study","volume":"52","author":"SJ Wood","year":"2010","journal-title":"Neuroimage"},{"issue":"8","key":"pone.0233670.ref013","doi-asserted-by":"crossref","first-page":"e868","DOI":"10.1038\/tp.2016.143","article-title":"Impact of polygenic schizophrenia-related risk and hippocampal volumes on the onset of psychosis","volume":"6","author":"F Harrisberger","year":"2016","journal-title":"Translational psychiatry"},{"issue":"298","key":"pone.0233670.ref014","article-title":"Emerging Temporal Lobe Dysfunction in People at Clinical High Risk for Psychosis","volume":"10","author":"P Allen","year":"2019","journal-title":"Frontiers in Psychiatry"},{"key":"pone.0233670.ref015","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3389\/fpsyt.2012.00096","article-title":"Hippocampal shape and volume changes with antipsychotics in early stage psychotic illness","volume":"3","author":"D Mamah","year":"2012","journal-title":"Front Psychiatry"},{"issue":"2","key":"pone.0233670.ref016","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1001\/archgenpsychiatry.2010.199","article-title":"Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia","volume":"68","author":"BC Ho","year":"2011","journal-title":"Arch Gen Psychiatry"},{"issue":"6","key":"pone.0233670.ref017","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.biopsych.2018.08.021","article-title":"The Hippocampus in Depression: More Than the Sum of Its Parts? Advanced Hippocampal Substructure Segmentation in Depression","volume":"85","author":"DW Roddy","year":"2019","journal-title":"Biol Psychiatry"},{"issue":"6","key":"pone.0233670.ref018","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.biopsych.2019.01.011","article-title":"Parsing the Hippocampus in Depression: Chronic Stress, Hippocampal Volume, and Major Depressive Disorder","volume":"85","author":"YI Sheline","year":"2019","journal-title":"Biol Psychiatry"},{"issue":"10","key":"pone.0233670.ref019","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.biopsych.2015.08.009","article-title":"Neuroanatomic Differences Associated With Stress Susceptibility and Resilience","volume":"79","author":"C Anacker","year":"2016","journal-title":"Biol Psychiatry"},{"key":"pone.0233670.ref020","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jpsychires.2016.11.010","article-title":"Childhood adversity impacts on brain subcortical structures relevant to depression","volume":"86","author":"T Frodl","year":"2017","journal-title":"J Psychiatr Res"},{"issue":"9","key":"pone.0233670.ref021","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1017\/S0033291711002960","article-title":"Prevalence of psychotic symptoms in childhood and adolescence: a systematic review and meta-analysis of population-based studies","volume":"42","author":"I Kelleher","year":"2012","journal-title":"Psychol Med"},{"issue":"6","key":"pone.0233670.ref022","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1017\/S0033291712001626","article-title":"An updated and conservative systematic review and meta-analysis of epidemiological evidence on psychotic experiences in children and adults: on the pathway from proneness to persistence to dimensional expression across mental disorders","volume":"43","author":"RJ Linscott","year":"2013","journal-title":"Psychol Med"},{"issue":"12","key":"pone.0233670.ref023","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1017\/S0033291710000358","article-title":"Extended psychosis phenotype\u2013yes: single continuum\u2013unlikely: a commentary on \u2018Why we need more debate on whether psychotic symptoms lie on a continuum with normality\u2019by David (2010)","volume":"40","author":"N Kaymaz","year":"2010","journal-title":"Psychological medicine"},{"key":"pone.0233670.ref024","unstructured":"Smeets F, Lataster T, van Winkel R, de Graaf R, Ten Have M, van Os J. Testing the hypothesis that psychotic illness begins when subthreshold hallucinations combine with"},{"issue":"4","key":"pone.0233670.ref025","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1017\/S0033291708003760","article-title":"Emotional and behavioural antecedents of young adults who screen positive for non-affective psychosis: a 21-year birth cohort study","volume":"39","author":"J Welham","year":"2009","journal-title":"Psychol Med"},{"issue":"11","key":"pone.0233670.ref026","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1001\/archpsyc.57.11.1053","article-title":"Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study","volume":"57","author":"R Poulton","year":"2000","journal-title":"Arch Gen Psychiatry"},{"issue":"5","key":"pone.0233670.ref027","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1001\/archgenpsychiatry.2011.1580","article-title":"Self-reported attenuated psychotic symptoms as forerunners of severe mental disorders later in life","volume":"69","author":"N Werbeloff","year":"2012","journal-title":"Arch Gen Psychiatry"},{"issue":"2","key":"pone.0233670.ref028","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/schbul\/sbr196","article-title":"Evidence that psychotic symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk, and severity\u2014implications for diagnosis and ultra-high risk research","volume":"38","author":"JT Wigman","year":"2012","journal-title":"Schizophr Bull"},{"key":"pone.0233670.ref029","article-title":"The Bidirectional Associations Between Psychotic Experiences and DSM-IV Mental Disorders","author":"JJ McGrath","year":"2016","journal-title":"The American journal of psychiatry"},{"issue":"9","key":"pone.0233670.ref030","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1001\/jamapsychiatry.2013.140","article-title":"Psychotic symptoms and population risk for suicide attempt: a prospective cohort study","volume":"70","author":"I Kelleher","year":"2013","journal-title":"JAMA Psychiatry"},{"issue":"1\u20133","key":"pone.0233670.ref031","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.schres.2010.03.001","article-title":"Psychotic-like experiences and correlation with distress and depressive symptoms in a community sample of adolescents and young adults","volume":"119","author":"M Armando","year":"2010","journal-title":"Schizophr Res"},{"issue":"1","key":"pone.0233670.ref032","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.schres.2010.05.028","article-title":"Language, motor and speed of processing deficits in adolescents with subclinical psychotic symptoms","volume":"123","author":"MM Blanchard","year":"2010","journal-title":"Schizophr Res"},{"issue":"5","key":"pone.0233670.ref033","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1093\/schbul\/sbs086","article-title":"Neurocognition in the extended psychosis phenotype: performance of a community sample of adolescents with psychotic symptoms on the MATRICS neurocognitive battery","volume":"39","author":"I Kelleher","year":"2013","journal-title":"Schizophr Bull"},{"issue":"3","key":"pone.0233670.ref034","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1093\/schbul\/sbm121","article-title":"Childhood trauma and psychotic disorders: a systematic, critical review of the evidence","volume":"34","author":"S Bendall","year":"2008","journal-title":"Schizophr Bull"},{"issue":"3","key":"pone.0233670.ref035","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.psychres.2015.04.052","article-title":"Impact of childhood adversities on the short-term course of illness in psychotic spectrum disorders","volume":"228","author":"I Schalinski","year":"2015","journal-title":"Psychiatry Res"},{"issue":"1","key":"pone.0233670.ref036","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1176\/appi.ajp.2010.10040567","article-title":"Childhood trauma and children's emerging psychotic symptoms: A genetically sensitive longitudinal cohort study","volume":"168","author":"L Arseneault","year":"2011","journal-title":"Am J Psychiatry"},{"issue":"4","key":"pone.0233670.ref037","doi-asserted-by":"crossref","first-page":"e0153557","DOI":"10.1371\/journal.pone.0153557","article-title":"Impact of Adverse Childhood Experiences on Psychotic-Like Symptoms and Stress Reactivity in Daily Life in Nonclinical Young Adults","volume":"11","author":"P Cristobal-Narvaez","year":"2016","journal-title":"PLoS One"},{"issue":"7","key":"pone.0233670.ref038","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1176\/appi.ajp.2013.12060768","article-title":"Psychotic experiences and psychotic disorders at age 18 in relation to psychotic experiences at age 12 in a longitudinal population-based cohort study","volume":"170","author":"S Zammit","year":"2013","journal-title":"Am J Psychiatry"},{"issue":"4","key":"pone.0233670.ref039","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1017\/S1121189X00002128","article-title":"The psychosis proneness: psychosis persistence model as an explanation for the association between urbanicity and psychosis","volume":"15","author":"J Spauwen","year":"2006","journal-title":"Epidemiol Psichiatr Soc"},{"issue":"7","key":"pone.0233670.ref040","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1176\/appi.ajp.2012.12091169","article-title":"Childhood trauma and psychosis in a prospective cohort study: cause, effect, and directionality","volume":"170","author":"I Kelleher","year":"2013","journal-title":"Am J Psychiatry"},{"key":"pone.0233670.ref041","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jad.2016.05.053","article-title":"Persistence or recurrence of non-psychotic comorbid mental disorders associated with 6-year poor functional outcomes in patients at ultra high risk for psychosis","volume":"203","author":"G Rutigliano","year":"2016","journal-title":"J Affect Disord"},{"issue":"2","key":"pone.0233670.ref042","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1093\/schbul\/sbr164","article-title":"Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinical interview study","volume":"38","author":"I Kelleher","year":"2012","journal-title":"Schizophr Bull"},{"issue":"7","key":"pone.0233670.ref043","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/00004583-199707000-00021","article-title":"Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data","volume":"36","author":"J Kaufman","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"2","key":"pone.0233670.ref044","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.neuroimage.2012.01.021","article-title":"FreeSurfer","volume":"62","author":"B Fischl","year":"2012","journal-title":"Neuroimage"},{"issue":"20","key":"pone.0233670.ref045","doi-asserted-by":"crossref","first-page":"11050","DOI":"10.1073\/pnas.200033797","article-title":"Measuring the thickness of the human cerebral cortex from magnetic resonance images","volume":"97","author":"B Fischl","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"2","key":"pone.0233670.ref046","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1006\/nimg.1998.0395","article-title":"Cortical surface-based analysis. I. Segmentation and surface reconstruction","volume":"9","author":"AM Dale","year":"1999","journal-title":"Neuroimage"},{"issue":"3","key":"pone.0233670.ref047","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"RS Desikan","year":"2006","journal-title":"Neuroimage"},{"issue":"3","key":"pone.0233670.ref048","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0896-6273(02)00569-X","article-title":"Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain","volume":"33","author":"B Fischl","year":"2002","journal-title":"Neuron"},{"issue":"2","key":"pone.0233670.ref049","first-page":"195","article-title":"Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system","volume":"9","author":"B Fischl","year":"1999","journal-title":"Neuroimage"},{"issue":"1","key":"pone.0233670.ref050","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/cercor\/bhg087","article-title":"Automatically parcellating the human cerebral cortex","volume":"14","author":"B Fischl","year":"2004","journal-title":"Cereb Cortex"},{"issue":"4","key":"pone.0233670.ref051","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1016\/j.neuroimage.2012.02.084","article-title":"Within-subject template estimation for unbiased longitudinal image analysis","volume":"61","author":"M Reuter","year":"2012","journal-title":"Neuroimage"},{"issue":"6","key":"pone.0233670.ref052","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1109\/TMI.2008.2010434","article-title":"Encoding probabilistic brain atlases using Bayesian inference","volume":"28","author":"K Van Leemput","year":"2009","journal-title":"IEEE Transactions on Medical Imaging"},{"key":"pone.0233670.ref053","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.neuroimage.2015.04.042","article-title":"A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI","volume":"115","author":"JE Iglesias","year":"2015","journal-title":"Neuroimage"},{"issue":"2","key":"pone.0233670.ref054","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.neuroimage.2004.06.018","article-title":"A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume","volume":"23","author":"RL Buckner","year":"2004","journal-title":"Neuroimage"},{"key":"pone.0233670.ref055","volume-title":"IBM SPSS Statistics for Windows, Version 21.0","author":"Corp I","year":"2012"},{"issue":"11","key":"pone.0233670.ref056","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v039.i11","article-title":"Computing the two-sided Kolmogorov-Smirnov distribution","volume":"39","author":"R Simard","year":"2011","journal-title":"Journal of Statistical Software"},{"key":"pone.0233670.ref057","volume-title":"Statistical power analysis for the behavioral sciences","author":"J Cohen","year":"1998","edition":"2"},{"issue":"2","key":"pone.0233670.ref058","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.1016\/j.neuroimage.2009.09.015","article-title":"Structural and functional brain correlates of subclinical psychotic symptoms in 11\u201313 year old schoolchildren","volume":"49","author":"S Jacobson","year":"2010","journal-title":"NeuroImage"},{"issue":"7","key":"pone.0233670.ref059","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1001\/jamapsychiatry.2015.0137","article-title":"White Matter Differences Among Adolescents Reporting Psychotic Experiences: A Population Based Diffusion Magnetic Resonance Imaging Study","volume":"72","author":"E O'Hanlon","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"7","key":"pone.0233670.ref060","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1002\/hbm.22796","article-title":"Schizophrenia-like topological changes in the structural connectome of individuals with subclinical psychotic experiences","volume":"36","author":"M Drakesmith","year":"2015","journal-title":"Hum Brain Mapp"},{"issue":"12","key":"pone.0233670.ref061","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1038\/mp.2015.66","article-title":"Connectome-wide network analysis of youth with Psychosis-Spectrum symptoms","volume":"20","author":"TD Satterthwaite","year":"2015","journal-title":"Mol Psychiatry"},{"issue":"5","key":"pone.0233670.ref062","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1001\/jamapsychiatry.2015.3463","article-title":"Structural Brain Abnormalities in Youth With Psychosis Spectrum Symptoms","volume":"73","author":"TD Satterthwaite","year":"2016","journal-title":"JAMA psychiatry"},{"issue":"5","key":"pone.0233670.ref063","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1001\/jamapsychiatry.2014.3169","article-title":"Functional neuroimaging abnormalities in youth with psychosis spectrum symptoms","volume":"72","author":"DH Wolf","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"pone.0233670.ref064","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11682-011-9141-4","article-title":"Structural changes in the hippocampus and amygdala at first episode of psychosis","volume":"6","author":"DR Watson","year":"2012","journal-title":"Brain Imaging Behav"},{"issue":"7","key":"pone.0233670.ref065","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1017\/S0033291712002218","article-title":"Amygdala-hippocampal shape and cortical thickness abnormalities in first-episode schizophrenia and mania","volume":"43","author":"A Qiu","year":"2013","journal-title":"Psychol Med"},{"key":"pone.0233670.ref066","article-title":"Gray matter differences between affective and non-affective first episode psychosis: A review of Magnetic Resonance Imaging studies","author":"A Calvo","year":"2018","journal-title":"J Affect Disord"},{"issue":"6","key":"pone.0233670.ref067","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1093\/schbul\/sbr085","article-title":"Childhoo trauma and hippocampal and amygdalar volumes in first-episode psychosis","volume":"38","author":"K Hoy","year":"2012","journal-title":"Schizophr Bull"},{"key":"pone.0233670.ref068","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.nbd.2012.03.012","article-title":"How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans","volume":"52","author":"T Frodl","year":"2013","journal-title":"Neurobiol Dis"},{"issue":"4","key":"pone.0233670.ref069","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.biopsych.2009.10.017","article-title":"Hippocampal changes associated with early-life adversity and vulnerability to depression","volume":"67","author":"U Rao","year":"2010","journal-title":"Biol Psychiatry"},{"issue":"8","key":"pone.0233670.ref070","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/S0006-3223(00)00998-7","article-title":"Effects of early advers experiences on brain structure and function: clinical implications","volume":"48","author":"J Kaufman","year":"2000","journal-title":"Biol Psychiatry"},{"issue":"4","key":"pone.0233670.ref071","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1348\/000712601162419","article-title":"Bullying and victimization of primary school children in England and Germany: Prevalence and school factors","volume":"92","author":"D Wolke","year":"2001","journal-title":"British journal of psychology"},{"issue":"16","key":"pone.0233670.ref072","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1001\/jama.285.16.2094","article-title":"Bullying behaviors among US youth: Prevalence and association with psychosocial adjustment","volume":"285","author":"TR Nansel","year":"2001","journal-title":"Jama"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0233670","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T13:35:13Z","timestamp":1591191313000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0233670"}},"subtitle":[],"editor":[{"given":"Danilo","family":"Arnone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,6,3]]},"references-count":72,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,6,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0233670","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,3]]}}}