{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:58:40Z","timestamp":1774526320039,"version":"3.50.1"},"reference-count":57,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T00:00:00Z","timestamp":1591747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0234076","type":"journal-article","created":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T17:42:30Z","timestamp":1591810950000},"page":"e0234076","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["\u03b2-glucan administration improves growth performance and gut health in New Zealand White and APRI rabbits with different breed responses"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1788-5082","authenticated-orcid":true,"given":"Mahmoud M.","family":"Abo Ghanima","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8306-0011","authenticated-orcid":true,"given":"Ayman H.","family":"Abd El-Aziz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed E.","family":"Noreldin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa S.","family":"Atta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaker A.","family":"Mousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9721-4360","authenticated-orcid":true,"given":"Ali H.","family":"El-Far","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2020,6,10]]},"reference":[{"key":"pone.0234076.ref001","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1439-0396.2009.00967.x","article-title":"Effect of different levels of bee pollen on performance and blood profile of New Zealand White bucks and growth performance of their offspring during summer and winter months","volume":"95","author":"YA Attia","year":"2011","journal-title":"J Anim Physiol Anim Nutr (Berl)"},{"key":"pone.0234076.ref002","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.meatsci.2011.02.017","article-title":"The role of rabbit meat as functional food","volume":"88","author":"A Dalle Zotte","year":"2011","journal-title":"Meat Sci"},{"key":"pone.0234076.ref003","article-title":"Fortification of rabbit diets with vitamin E or selenium affects growth performance, lipid peroxidation, oxidative status and immune response in growing rabbits","author":"TA Ebeid","year":"2013","journal-title":"Livest Sci"},{"key":"pone.0234076.ref004","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/nu1020111","article-title":"Development of Rabbit Meat Products Fortified With n-3 Polyunsaturated Fatty Acids","volume":"1","author":"M Petracci","year":"2009","journal-title":"Nutrients"},{"key":"pone.0234076.ref005","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0301-6226(01)00308-6","article-title":"Perception of rabbit meat quality and major factors influencing the rabbit carcass and meat quality","volume":"75","author":"A. Dalle Zotte","year":"2002","journal-title":"Livest Prod Sci"},{"key":"pone.0234076.ref006","first-page":"127","article-title":"Alternatives to antibiotic growth promoters in rabbit feeding: a review","volume":"15","author":"L. Falc\u00e3o-e-Cunha","year":"2010","journal-title":"World Rabbit Sci"},{"key":"pone.0234076.ref007","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1462-5822.2005.00505.x","article-title":"Immune recognition of fungal \u03b2-glucans","volume":"7","author":"GD Brown","year":"2005","journal-title":"Cell Microbiol"},{"key":"pone.0234076.ref008","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.ijbiomac.2006.08.009","article-title":"Orally administered marine (1\u21923)-\u03b2-d-glucan Phycarine stimulates both humoral and cellular immunity","volume":"40","author":"V Vetvicka","year":"2007","journal-title":"Int J Biol Macromol"},{"key":"pone.0234076.ref009","first-page":"1412791","article-title":"Lentinula edodes \u03b2-glucan enriched diet induces pro- and anti-inflammatory macrophages in rabbit","volume":"61","author":"H Crespo","year":"2017","journal-title":"Food Nutr Res. Swedish Nutrition Foundation"},{"key":"pone.0234076.ref010","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.3382\/ps.2008-00147","article-title":"Direct Enhancement of the Phagocytic and Bactericidal Capability of Abdominal Macrophage of Chicks by -1,3\u20131,6-Glucan","volume":"87","author":"K-L Chen","year":"2008","journal-title":"Poult Sci"},{"key":"pone.0234076.ref011","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.2527\/2006.8461422x","article-title":"Effects of supplementation of \u03b2-glucans on growth performance, nutrient digestibility, and immunity in weanling pigs","volume":"84","author":"T-W Hahn","year":"2006","journal-title":"J Anim Sci"},{"key":"pone.0234076.ref012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-2427(99)00006-9","article-title":"The effect of nonspecific immunostimulation of pregnant mares with 1,3\/1,6 glucan and levamisole on the immunoglobulins levels in colostrum, selected indices of nonspecific cellular and humoral immunity in foals in neonatal and postnatal period","volume":"68","author":"L Krakowski","year":"1999","journal-title":"Vet Immunol Immunopathol"},{"key":"pone.0234076.ref013","volume-title":"Nutrient Requirements of Rabbits","author":"NRC","year":"1977"},{"key":"pone.0234076.ref014","doi-asserted-by":"crossref","DOI":"10.1079\/9781845936693.0000","author":"C De Blas","year":"2010","journal-title":"The Nutrition of the Rabbit Edited by"},{"key":"pone.0234076.ref015","first-page":"236","article-title":"The role of nutrition in genetics","volume":"29","author":"WV Lambert","year":"1936","journal-title":"Am Res Soc Anim Prod"},{"key":"pone.0234076.ref016","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4995\/wrs.1996.278","article-title":"Harmonization of criteria and terminology in rabbit meat research. Revised proposal","volume":"4","author":"A. Blasco","year":"2010","journal-title":"World Rabbit Sci"},{"key":"pone.0234076.ref017","volume-title":"Theory Practice of histological techniques","author":"J Bancroft","year":"2013","edition":"7"},{"key":"pone.0234076.ref018","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3390\/ijms19020462","article-title":"Influence of Graded Levels of l-Theanine Dietary Supplementation on Growth Performance, Carcass Traits, Meat Quality, Organs Histomorphometry, Blood Chemistry and Immune Response of Broiler Chickens","volume":"19","author":"M Saeed","year":"2018","journal-title":"Int J Mol Sci"},{"key":"pone.0234076.ref019","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.livsci.2016.07.019","article-title":"The effect of dietary supplementation of the broiler chicken diet with Boswellia serrata resin on growth performance, digestibility, and gastrointestinal characteristics, morphology, and microbiota","volume":"191","author":"B Kiczorowska","year":"2016","journal-title":"Livest Sci"},{"key":"pone.0234076.ref020","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10974-005-9007-8","article-title":"In ovo neuromuscular stimulation alters the skeletal muscle phenotype of the chick","volume":"26","author":"JL Heywood","year":"2005","journal-title":"J Muscle Res Cell Motil"},{"key":"pone.0234076.ref021","doi-asserted-by":"crossref","first-page":"e77774","DOI":"10.1371\/journal.pone.0077774","article-title":"An optimized histochemical method to assess skeletal muscle glycogen and lipid stores reveals two metabolically distinct populations of type I muscle fibers","volume":"8","author":"C Prats","year":"2013","journal-title":"PLoS One. Public Library of Science"},{"key":"pone.0234076.ref022","doi-asserted-by":"crossref","first-page":"45e","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"MW Pfaffl","year":"2001","journal-title":"Nucleic Acids Res"},{"key":"pone.0234076.ref023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/3001478","article-title":"Multiple Range and Multiple F Tests","volume":"11","author":"DB Duncan","year":"1955","journal-title":"Biometrics"},{"key":"pone.0234076.ref024","doi-asserted-by":"crossref","first-page":"23","DOI":"10.5455\/ajvs.163992","article-title":"The Growth Promoting Effect of Beta-glucan in Comparison with Sodium Butyrate in Broiler Chicks","volume":"44","author":"A ElSawy","year":"2015","journal-title":"Alexandria J Vet Sci"},{"key":"pone.0234076.ref025","first-page":"85","article-title":"Performance, blood profile, carcass and meat traits and tissue morphology in growing rabbits fed mannanoligosaccharides and zinc-bacitracin continuously or intermittently","volume":"33","author":"YA Attia","year":"2015","journal-title":"Anim Sci Pap Reports"},{"key":"pone.0234076.ref026","first-page":"23","article-title":"Effect of yeast supplementation and alternative housing systems on performance of rabbits","volume":"53","author":"S Khanna","year":"2014","journal-title":"Haryana Vet"},{"key":"pone.0234076.ref027","doi-asserted-by":"crossref","first-page":"384","DOI":"10.5713\/ajas.15.0141","article-title":"Effect of Dietary Beta-Glucan on the Performance of Broilers and the Quality of Broiler Breast Meat","volume":"29","author":"SH Moon","year":"2016","journal-title":"Asian-Australasian J Anim Sci"},{"key":"pone.0234076.ref028","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1136\/gut.52.7.988","article-title":"Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC)","volume":"52","author":"S Resta-Lenert","year":"2003","journal-title":"Gut"},{"key":"pone.0234076.ref029","first-page":"75","article-title":"Effect of amino yeast addition on growth performance, digestion, carcass traits and economical efficiency of growing rabbit","volume":"15","author":"SA Shehata","year":"2012","journal-title":"Egypt J Nutr Feed"},{"key":"pone.0234076.ref030","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1093\/ps\/84.7.1015","article-title":"Effects of yeast (Saccharomyces cerevisiae) cell components on growth performance, meat quality, and ileal mucosa development of broiler chicks","volume":"84","author":"AW Zhang","year":"2005","journal-title":"Poult Sci"},{"key":"pone.0234076.ref031","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00580-010-1066-6","article-title":"Determination of the effect of probiotic (Saccharomyces cerevisiae) on growth performance and hematological parameters of rabbits","volume":"21","author":"C Ezema","year":"2012","journal-title":"Comp Clin Path"},{"key":"pone.0234076.ref032","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1080\/09712119.2016.1174126","article-title":"Effect of probiotic supplementation on growth performance, nutrient utilization and carcass characteristics of growing Chinchilla rabbits","volume":"45","author":"RS Bhatt","year":"2017","journal-title":"J Appl Anim Res"},{"key":"pone.0234076.ref033","first-page":"220","article-title":"Growth performance of male NZW rabbits fed diets supplemented with beneficial bacteria or live yeast","volume":"19","author":"AY El-Badawi","year":"2018","journal-title":"Agric Eng Int CIGR J"},{"key":"pone.0234076.ref034","doi-asserted-by":"crossref","first-page":"31971","DOI":"10.1007\/s11356-018-3197-2","article-title":"Probiotics and plant-derived compounds as eco-friendly agents to inhibit microbial toxins in poultry feed: a comprehensive review","volume":"25","author":"ME Abd El-Hack","year":"2018","journal-title":"Environ Sci Pollut Res"},{"key":"pone.0234076.ref035","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3389\/fvets.2018.00245","article-title":"Review: Roles of Prebiotics in Intestinal Ecosystem of Broilers","volume":"5","author":"P-Y Teng","year":"2018","journal-title":"Front Vet Sci"},{"key":"pone.0234076.ref036","article-title":"Effect of adding chicory fructans in feed on broiler growth performance, serum cholesterol and intestinal length","author":"TC Chen","year":"2003","journal-title":"Int J Poult Sci. Citeseer"},{"key":"pone.0234076.ref037","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0008-8749(03)00061-3","article-title":"Immunopotentiation of intraepithelial lymphocytes in the intestine by oral administrations of beta-glucan","volume":"221","author":"C Tsukada","year":"2003","journal-title":"Cell Immunol"},{"key":"pone.0234076.ref038","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.3382\/ps.2013-03029","article-title":"-1,3\/1,6-Glucan alleviated intestinal mucosal barrier impairment of broiler chickens challenged with Salmonella enterica serovar Typhimurium","volume":"92","author":"Y Shao","year":"2013","journal-title":"Poult Sci"},{"key":"pone.0234076.ref039","first-page":"602","article-title":"Effects of different doses of probiotic yeast Saccharomyces cerevisiae on the duodenal mucosa in rabbits","volume":"49","author":"N Seyidoglu","year":"2015","journal-title":"Indian J Anim Res"},{"key":"pone.0234076.ref040","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.anifeedsci.2016.03.009","article-title":"Effects of dietary yeast \u03b2-glucans supplementation on growth performance, gut morphology, intestinal Clostridium perfringens population and immune response of broiler chickens challenged with necrotic enteritis","volume":"215","author":"X Tian","year":"2016","journal-title":"Anim Feed Sci Technol"},{"key":"pone.0234076.ref041","doi-asserted-by":"crossref","first-page":"e0196579","DOI":"10.1371\/journal.pone.0196579","article-title":"Barley \u03b2-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice","volume":"13","author":"J Miyamoto","year":"2018","journal-title":"PLoS One"},{"key":"pone.0234076.ref042","article-title":"Training decreases muscle glycogen turnover during exercise","author":"JL Azevedo","year":"1998","journal-title":"Eur J Appl Physiol Occup Physiol"},{"key":"pone.0234076.ref043","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.carbpol.2012.10.023","article-title":"Effects of oat \u03b2-glucan on endurance exercise and its anti-fatigue properties in trained rats","volume":"92","author":"C Xu","year":"2013","journal-title":"Carbohydr Polym"},{"key":"pone.0234076.ref044","doi-asserted-by":"crossref","first-page":"191","DOI":"10.4995\/wrs.2016.3991","article-title":"Effect of diet supplementation with live yeast Saccharomyces cerevisiae on growth performance, caecal ecosystem and health of growing rabbits","volume":"24","author":"T Belhassen","year":"2016","journal-title":"World Rabbit Sci"},{"key":"pone.0234076.ref045","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.vetimm.2006.07.007","article-title":"Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections","volume":"114","author":"YH Hong","year":"2006","journal-title":"Vet Immunol Immunopathol"},{"key":"pone.0234076.ref046","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1038\/mi.2015.13","article-title":"Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ Treg cell function in the intestine","volume":"8","author":"OJ Harrison","year":"2015","journal-title":"Mucosal Immunol"},{"key":"pone.0234076.ref047","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.3382\/ps.2010-00987","article-title":"Immune responses to dietary -glucan in broiler chicks during an Eimeria challenge","volume":"89","author":"CM Cox","year":"2010","journal-title":"Poult Sci"},{"key":"pone.0234076.ref048","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1081\/IPH-120024513","article-title":"The influence of beta-glucan on immune responses in broiler chicks","volume":"25","author":"Y Guo","year":"2003","journal-title":"Immunopharmacol Immunotoxicol"},{"key":"pone.0234076.ref049","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/17450390500247832","article-title":"Effects of \u03b2-glucan extracted from Saccharomyces cerevisiae on humoral and cellular immunity in weaned piglets","volume":"59","author":"J Li","year":"2005","journal-title":"Arch Anim Nutr"},{"key":"pone.0234076.ref050","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/01.shk.0000245030.24235.f1","article-title":"Beta-glucan attenuates inflammatory cytokine release and prevents acute lung injury in an experimental model of sepsis","volume":"27","author":"A Bedirli","year":"2007","journal-title":"Shock"},{"key":"pone.0234076.ref051","volume-title":"Veterinary Immunology","author":"IR Tizard","year":"2013"},{"key":"pone.0234076.ref052","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.3382\/ps.2010-00865","article-title":"Performance and immune responses to dietary -glucan in broiler chicks","volume":"89","author":"CM Cox","year":"2010","journal-title":"Poult Sci"},{"key":"pone.0234076.ref053","first-page":"G15","article-title":"Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning","volume":"284","author":"H. Jaeschke","year":"2003","journal-title":"Am J Physiol Liver Physiol"},{"key":"pone.0234076.ref054","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ajme.2017.09.001","article-title":"First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid","volume":"54","author":"OM Ighodaro","year":"2018","journal-title":"Alexandria J Med"},{"key":"pone.0234076.ref055","doi-asserted-by":"crossref","first-page":"539","DOI":"10.5455\/medscience.2016.05.8429","article-title":"Protective effects of melatonin and and #914;-D-Glucan against acetaminophen toxicity in rats","volume":"5","author":"M Aydogan","year":"2016","journal-title":"Med Sci | Int Med J"},{"key":"pone.0234076.ref056","doi-asserted-by":"crossref","first-page":"29745","DOI":"10.1074\/jbc.273.45.29745","article-title":"The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton","volume":"273","author":"AS Fanning","year":"1998","journal-title":"J Biol Chem"},{"key":"pone.0234076.ref057","first-page":"2751","article-title":"Fungal beta-(1\u20133)-D-glucan derivatives exhibit high antioxidative and antimutagenic activity in vitro","volume":"23","author":"L Krizkov\u00e1","year":"2003","journal-title":"Anticancer Res"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0307562","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"record-id":"63087"},{"DOI":"10.1371\/journal.pone.0307562","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0234076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T17:42:49Z","timestamp":1591810969000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0234076"}},"subtitle":[],"editor":[{"given":"Cristina","family":"\u00d3vilo","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,6,10]]},"references-count":57,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,6,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0234076","relation":{"retraction":[{"id-type":"doi","id":"10.1371\/journal.pone.0307562","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,10]]}}}