{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T21:24:51Z","timestamp":1778534691656,"version":"3.51.4"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T00:00:00Z","timestamp":1591660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012151","name":"Sanming Project of Medicine in Shenzhen","doi-asserted-by":"publisher","award":["SZSM201611077"],"award-info":[{"award-number":["SZSM201611077"]}],"id":[{"id":"10.13039\/501100012151","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0234261","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T17:38:45Z","timestamp":1591724325000},"page":"e0234261","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["Cross-sectional study of asymptomatic Neisseria gonorrhoeae and Chlamydia trachomatis infections in sexually transmitted disease related clinics in Shenzhen, China"],"prefix":"10.1371","volume":"15","author":[{"given":"Shu-Xia","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang-Kang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Ting","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Sheng","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6086-6744","authenticated-orcid":true,"given":"Yu-Mao","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2020,6,9]]},"reference":[{"issue":"8","key":"pone.0234261.ref001","doi-asserted-by":"crossref","first-page":"548","DOI":"10.2471\/BLT.18.228486","article-title":"Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016","volume":"97","author":"J Rowley","year":"2019","journal-title":"Bull World Health Organ"},{"issue":"4","key":"pone.0234261.ref002","first-page":"187","article-title":"Rebound in Sexually Transmitted Infections Following the Success of Antiretrovirals for HIV\/AIDS","volume":"20","author":"V Soriano","year":"2018","journal-title":"AIDS Rev"},{"issue":"1","key":"pone.0234261.ref003","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1136\/sti.75.1.3","article-title":"From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection","volume":"75","author":"DT Fleming","year":"1999","journal-title":"Sex Transm Infect"},{"issue":"3","key":"pone.0234261.ref004","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/OLQ.0b013e318285c6d2","article-title":"The estimated direct medical cost of selected sexually transmitted infections in the United States, 2008","volume":"40","author":"K Owusu-Edusei","year":"2013","journal-title":"Sex Transm Dis"},{"issue":"1","key":"pone.0234261.ref005","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/sti.2009.037440","article-title":"HIV prevalence and related risk factors among male sex workers in Shenzhen, China: results from a time-location sampling survey","volume":"86","author":"WD Cai","year":"2010","journal-title":"Sex Transm Infect"},{"issue":"4","key":"pone.0234261.ref006","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1136\/sextrans-2011-050163","article-title":"Molecular epidemiology of genital Chlamydia trachomatis infection in Shenzhen, China","volume":"88","author":"JJ Zhang","year":"2012","journal-title":"Sex Transm Infect"},{"issue":"10","key":"pone.0234261.ref007","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1001\/jama.289.10.1265","article-title":"Population-based study of chlamydial infection in China: a hidden epidemic","volume":"289","author":"WL Parish","year":"2003","journal-title":"Jama"},{"issue":"12","key":"pone.0234261.ref008","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1177\/0956462414523260","article-title":"Evaluation of syndromic management of sexually transmitted infections within the Kisumu Incidence Cohort Study","volume":"25","author":"FO Otieno","year":"2014","journal-title":"Int J STD AIDS"},{"issue":"1","key":"pone.0234261.ref009","doi-asserted-by":"crossref","first-page":"E2","DOI":"10.1136\/sti.78.1.e2","article-title":"Syndromic management of sexually transmitted diseases at primary care level, Mozambique","volume":"78","author":"FS Mbofana","year":"2002","journal-title":"Sex Transm Infect"},{"issue":"5","key":"pone.0234261.ref010","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/tmi.13046","article-title":"Accuracy of syndromic management in targeting vaginal and cervical infections among symptomatic women of reproductive age attending primary care clinics in Dakar, Senegal","volume":"23","author":"MS Barry","year":"2018","journal-title":"Trop Med Int Health"},{"issue":"1","key":"pone.0234261.ref011","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1186\/s12879-018-3380-6","article-title":"A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts","volume":"18","author":"A Kaida","year":"2018","journal-title":"BMC Infect Dis"},{"issue":"7","key":"pone.0234261.ref012","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1136\/sti.2008.032011","article-title":"Low effectiveness of syndromic treatment services for curable sexually transmitted infections in rural South Africa","volume":"84","author":"RG White","year":"2008","journal-title":"Sex Transm Infect"},{"issue":"6","key":"pone.0234261.ref013","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1136\/sti.78.6.406","article-title":"Cost effectiveness of screening for Chlamydia trachomatis: a review of published studies","volume":"78","author":"E Honey","year":"2002","journal-title":"Sex Transm Infect"},{"issue":"9","key":"pone.0234261.ref014","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1258\/0956462991914717","article-title":"A one-year survey of gonococcal infection seen in the genitourinary medicine department of a London district general hospital","volume":"10","author":"DA Lewis","year":"1999","journal-title":"Int J STD AIDS"},{"issue":"8","key":"pone.0234261.ref015","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.cmi.2017.02.020","article-title":"Asymptomatic and symptomatic urethral gonorrhoea in men who have sex with men attending a sexual health service","volume":"23","author":"JJ Ong","year":"2017","journal-title":"Clin Microbiol Infect"},{"issue":"9","key":"pone.0234261.ref016","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1111\/tmi.12742","article-title":"Evaluation of syndromic management guidelines for treatment of sexually transmitted infections in South African women","volume":"21","author":"L van der Eem","year":"2016","journal-title":"Trop Med Int Health"},{"issue":"1","key":"pone.0234261.ref017","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/infdis\/jis298","article-title":"Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa","volume":"206","author":"K Mlisana","year":"2012","journal-title":"J Infect Dis"},{"issue":"7","key":"pone.0234261.ref018","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1136\/sextrans-2016-052950","article-title":"Neisseria gonorrhoeae DNA bacterial load in men with symptomatic and asymptomatic gonococcal urethritis","volume":"93","author":"D Priest","year":"2017","journal-title":"Sex Transm Infect"},{"issue":"2","key":"pone.0234261.ref019","doi-asserted-by":"crossref","first-page":"e0172561","DOI":"10.1371\/journal.pone.0172561","article-title":"Prevalence and risk factors of chlamydia infection in Hong Kong: A population-based geospatial household survey and testing","volume":"12","author":"WC Wong","year":"2017","journal-title":"PloS one"},{"issue":"9907","key":"pone.0234261.ref020","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/S0140-6736(13)61947-9","article-title":"Prevalence, risk factors, and uptake of interventions for sexually transmitted infections in Britain: findings from the National Surveys of Sexual Attitudes and Lifestyles (Natsal)","volume":"382","author":"P Sonnenberg","year":"2013","journal-title":"Lancet (London, England)"},{"issue":"5","key":"pone.0234261.ref021","doi-asserted-by":"crossref","first-page":"e0196516","DOI":"10.1371\/journal.pone.0196516","article-title":"Population-based study of chlamydial and gonococcal infections among women in Shenzhen, China: Implications for programme planning","volume":"13","author":"ZZ Luo","year":"2018","journal-title":"PloS one"},{"issue":"2","key":"pone.0234261.ref022","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/OLQ.0000000000000394","article-title":"Risk Factors for Incident and Redetected Chlamydia trachomatis Infection in Women: Results of a Population-Based Cohort Study","volume":"43","author":"E Harder","year":"2016","journal-title":"Sex Transm Dis"},{"issue":"5","key":"pone.0234261.ref023","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/OLQ.0b013e3181924386","article-title":"Incidence and risk factors for genital Chlamydia trachomatis infection: a 4-year prospective cohort study","volume":"36","author":"FE Skjeldestad","year":"2009","journal-title":"Sex Transm Dis"},{"issue":"2","key":"pone.0234261.ref024","doi-asserted-by":"crossref","first-page":"128","DOI":"10.7326\/0003-4819-147-2-200707170-00172","article-title":"Preventive Services Task Force recommendation statement","volume":"147","author":"Force USPST. Screening for chlamydial infection: U.S","year":"2007","journal-title":"Ann Intern Med"},{"issue":"5","key":"pone.0234261.ref025","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1177\/0956462415618837","article-title":"2015 European guideline on the management of Chlamydia trachomatis infections","volume":"27","author":"E Lanjouw","year":"2016","journal-title":"Int J STD AIDS"},{"issue":"9","key":"pone.0234261.ref026","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1097\/OLQ.0000000000000824","article-title":"Is Screening for Chlamydia and Gonorrhea in Men Who Have Sex With Men Associated With Reduction of the Prevalence of these Infections? A Systematic Review of Observational Studies","volume":"45","author":"A Tsoumanis","year":"2018","journal-title":"Sex Transm Dis"},{"issue":"2","key":"pone.0234261.ref027","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1097\/OLQ.0b013e31823e2ff7","article-title":"Chlamydia trachomatis trends in the United States among persons 14 to 39 years of age, 1999\u20132008","volume":"39","author":"SD Datta","year":"2012","journal-title":"Sex Transm Dis"},{"issue":"8","key":"pone.0234261.ref028","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1097\/OLQ.0b013e318254c837","article-title":"Self-reported Chlamydia testing rates of sexually active women aged 15\u201325 years in the United States, 2006\u20132008","volume":"39","author":"G Tao","year":"2012","journal-title":"Sex Transm Dis"},{"issue":"4","key":"pone.0234261.ref029","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1097\/OLQ.0000000000000963","article-title":"Low Chlamydia and Gonorrhea Testing Rates Among Men Who Have Sex With Men in Guangdong and Shandong Provinces, China","volume":"46","author":"D Wu","year":"2019","journal-title":"Sex Transm Dis"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0234261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T17:39:09Z","timestamp":1591724349000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0234261"}},"subtitle":[],"editor":[{"given":"Remco PH","family":"Peters","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,6,9]]},"references-count":29,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2020,6,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0234261","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,9]]}}}