{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T06:48:08Z","timestamp":1781592488629,"version":"3.54.5"},"reference-count":68,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0237424","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T19:16:34Z","timestamp":1598987794000},"page":"e0237424","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":39,"title":["Developing target product profiles for Neisseria gonorrhoeae diagnostics in the context of antimicrobial resistance: An expert consensus"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5480-7940","authenticated-orcid":true,"given":"Cecilia","family":"Ferreyra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Osborn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Moussy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Alirol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Lahra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Whiley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Shafer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Unemo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Klausner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Kelly Cirino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teodora","family":"Wi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"issue":"8","key":"pone.0237424.ref001","doi-asserted-by":"crossref","first-page":"548","DOI":"10.2471\/BLT.18.228486","article-title":"Chlamydia, gonorrhoea, trichomoniasis and syphilis: Global prevalence and incidence estimates, 2016","volume":"97","author":"J Rowley","year":"2019","journal-title":"Bull World Health Organ"},{"key":"pone.0237424.ref002","unstructured":"2018 Report on global sexually transmitted infection surveillance [Internet]. 2018 [cited 2019 Jun 27]. Available from: http:\/\/apps.who.int\/bookorders."},{"issue":"7","key":"pone.0237424.ref003","doi-asserted-by":"crossref","first-page":"e1002344","DOI":"10.1371\/journal.pmed.1002344","article-title":"Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action","volume":"14","author":"T Wi","year":"2017","journal-title":"PLOS Med"},{"key":"pone.0237424.ref004","article-title":"Antimicrobial resistance in Neisseria gonorrhoeae in the 21st Century: Past, evolution, and future","author":"M Unemo","year":"2014","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"pone.0237424.ref005","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1071\/SH19023","article-title":"World Health Organization Global Gonococcal Antimicrobial Surveillance Program (WHO GASP): review of new data and evidence to inform international collaborative actions and research efforts","volume":"16","author":"M Unemo","year":"2019","journal-title":"Sex Health"},{"key":"pone.0237424.ref006","article-title":"Zoliflodacin: An oral spiropyrimidinetrione antibiotic for the treatment of Neisseria gonorrhoeae, including multi-drug resistant isolates","author":"PA Bradford","year":"2020","journal-title":"ACS Infect Dis"},{"key":"pone.0237424.ref007","unstructured":"Taylor SN, Morris DH, Avery AK, Workowski KA, Batteiger BE, Tiffany CA, et al. Clinical Infectious Diseases Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation."},{"key":"pone.0237424.ref008","unstructured":"Implementation of the Global Strategy for Prevention and Control of Sexually Transmitted Infections: 2006\u20132015 PROGRESS REPORT [Internet]. 2015 [cited 2019 Jul 31]. Available from: www.who.int\/about\/licensing\/copyright_form\/en\/index.html"},{"issue":"1","key":"pone.0237424.ref009","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/infdis\/jis298","article-title":"Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa","volume":"206","author":"K Mlisana","year":"2012","journal-title":"J Infect Dis"},{"issue":"6","key":"pone.0237424.ref010","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1136\/sti.2004.013276","article-title":"Aetiology of sexually transmitted infections and response to syndromic treatment in southwest Uganda","volume":"81","author":"JM Pickering","year":"2005","journal-title":"Sex Transm Infect"},{"key":"pone.0237424.ref011","volume-title":"Diagnosing sexually transmitted infections in resource-constrained settings: challenges and ways forward","author":"TE Wi","year":"2019"},{"issue":"1","key":"pone.0237424.ref012","doi-asserted-by":"crossref","first-page":"849","DOI":"10.4102\/sajhivmed.v20i1.849","article-title":"Sexually transmitted infections, the silent partner in HIV-infected women in Zimbabwe","volume":"20","author":"S Lowe","year":"2019","journal-title":"South Afr J HIV Med"},{"issue":"3","key":"pone.0237424.ref013","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1056\/NEJM197401172900301","article-title":"Asymptomatic Gonorrhea in Men: Diagnosis, Natural Course, Prevalence and Significance","volume":"290","author":"HH Handsfield","year":"1974","journal-title":"N Engl J Med"},{"key":"pone.0237424.ref014","first-page":"68","volume-title":"Sexually transmitted infections in womenScandinavian Journal of Clinical and Laboratory Investigation","author":"B Van Der Pol","year":"2014"},{"key":"pone.0237424.ref015","doi-asserted-by":"crossref","unstructured":"Van Gemert C, Hellard M, Bradshaw C CS, Fowkes FJI, Agius PA, Bennett CM. Syndromic management of sexually transmissible infections in resource-poor settings: a systematic review with meta-analysis of the abnormal vaginal discharge flowchart for Neisseria gonorrhoea and Chlamydia trachomatis. [cited 2019 Apr 5]; Available from: https:\/\/doi.org\/10.1071\/SH17070","DOI":"10.1071\/SH17070"},{"key":"pone.0237424.ref016","unstructured":"UNAIDS. Consultation on STD interventions for preventing HIV: what is the evidence? [Internet]. 2000 [cited 2019 Jul 31]. Available from: http:\/\/www.unaids.org"},{"issue":"9069","key":"pone.0237424.ref017","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1016\/S0140-6736(97)02190-9","article-title":"Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1","volume":"349","author":"AIDSCAP Malawi Research Group","year":"1997","journal-title":"Lancet (London, England)"},{"issue":"4","key":"pone.0237424.ref018","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0211682","article-title":"Prevalence and factors associated with gonorrhea infection with respect to anatomic distributions among men who have sex with men","volume":"14","author":"J Budkaew","year":"2019","journal-title":"PLoS One"},{"key":"pone.0237424.ref019","first-page":"401","volume-title":"Epidemiology of gonorrhoea: A global perspective. Vol. 16, Sexual HealthCSIRO","author":"RD Kirkcaldy","year":"2019"},{"key":"pone.0237424.ref020","unstructured":"WHO | Global health sector strategy on Sexually Transmitted Infections, 2016\u20132021. WHO [Internet]. 2016 [cited 2019 Apr 4]; Available from: https:\/\/www.who.int\/reproductivehealth\/publications\/rtis\/ghss-stis\/en\/"},{"key":"pone.0237424.ref021","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1136\/sti.2002.004101","article-title":"Approaches to the control of sexually transmitted infections in developing countries: old problems and modern challenges","volume":"80","author":"P Mayaud","year":"2004","journal-title":"Sex Transm Infect"},{"issue":"7580","key":"pone.0237424.ref022","doi-asserted-by":"crossref","first-page":"S50","DOI":"10.1038\/nature16038","article-title":"Expanding the role of diagnostic and prognostic tools for infectious diseases in resource-poor settings","volume":"528","author":"AC Ghani","year":"2015","journal-title":"Nature"},{"key":"pone.0237424.ref023","article-title":"Targeted point-of-care testing compared with syndromic management of urogenital infections in women (WISH): a cross-sectional screening and diagnostic accuracy study","author":"MC Verwijs","year":"2019","journal-title":"Lancet Infect Dis"},{"issue":"6","key":"pone.0237424.ref024","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1586\/14787210.2014.880651","article-title":"Point of care diagnostics for sexually transmitted infections: perspectives and advances","volume":"12","author":"C Gaydos","year":"2014","journal-title":"Expert Rev Anti Infect Ther"},{"issue":"1","key":"pone.0237424.ref025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1155\/2005\/323082","article-title":"The laboratory diagnosis of Neisseria gonorrhoeae","volume":"16","author":"L-K Ng","year":"2005","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"pone.0237424.ref026","author":"MM Murtagh","journal-title":"The Point-of-Care Diagnostic Landscape for Sexually Transmitted Infections"},{"issue":"4","key":"pone.0237424.ref027","first-page":"175","article-title":"Detection of gonococcal infection: pros and cons of a rapid test","volume":"9","author":"P Vickerman","year":"2005","journal-title":"Mol Diagn"},{"key":"pone.0237424.ref028","first-page":"S16","volume-title":"Performance and operational characteristics of point-of-care tests for the diagnosis of urogenital gonococcal infections. Vol. 93, Sexually transmitted infections","author":"RJ Guy","year":"2017"},{"key":"pone.0237424.ref029","first-page":"S22","volume-title":"Systematic reviews of point-of-care tests for the diagnosis of urogenital Chlamydia trachomatis infections. Vol. 93, Sexually transmitted infections","author":"H Kelly","year":"2017"},{"issue":"3","key":"pone.0237424.ref030","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1128\/JCM.02235-16","article-title":"Stability studies on dry swabs and wet mailed swabs for detection of chlamydia trachomatis and neisseria gonorrhoeae in aptima assays","volume":"55","author":"J Moncada","year":"2017","journal-title":"J Clin Microbiol"},{"issue":"1","key":"pone.0237424.ref031","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/sextrans-2014-051891","article-title":"Diagnostic accuracy of rapid tests for sexually transmitted infections in symptomatic women","volume":"92","author":"L Nu\u00f1ez-Forero","year":"2016","journal-title":"Sex Transm Infect"},{"issue":"12","key":"pone.0237424.ref032","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1099\/jmm.0.034116-0","article-title":"A laboratory-based evaluation of the BioStar Optical ImmunoAssay point-of-care test for diagnosing Neisseria gonorrhoeae infection","volume":"60","author":"A Samarawickrama","year":"2011","journal-title":"J Med Microbiol"},{"key":"pone.0237424.ref033","author":"NS Abbai","year":"2015","journal-title":"Clinical Evaluation of the OneStep Gonorrhea RapiCard InstaTest for Detection of Neisseria gonorrhoeae in Symptomatic Patients from KwaZulu-Natal, South Africa"},{"key":"pone.0237424.ref034","unstructured":"Vickerman P, Watts C, Alary M, Mabey D, Peeling RW, Vickerman P. Sensitivity requirements for the point of care diagnosis of Chlamydia trachomatis and Neisseria gonorrhoeae in women [Internet]. [cited 2019 Mar 28]. Available from: www.stijournal.com"},{"key":"pone.0237424.ref035","unstructured":"Murtagh MM. The Point-of-Care Diagnostic Landscape for Sexually Transmitted Infections (STIs) [Internet]. 2018 [cited 2019 Jan 28]. Available from: https:\/\/www.who.int\/reproductivehealth\/topics\/rtis\/Diagnostic_Landscape_2018.pdf"},{"key":"pone.0237424.ref036","article-title":"Advancing prevention of sexually transmitted infections through point-of-care testing: target product profiles and landscape analysis","author":"I Toskin","year":"2017","journal-title":"Sex Transm Infect"},{"issue":"9","key":"pone.0237424.ref037","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1080\/14737159.2017.1360137","article-title":"Recent advances in the development and use of molecular tests to predict antimicrobial resistance in Neisseria gonorrhoeae","volume":"17","author":"V Don\u00e0","year":"2017","journal-title":"Expert Rev Mol Diagn"},{"issue":"7","key":"pone.0237424.ref038","doi-asserted-by":"crossref","first-page":"e1002344","DOI":"10.1371\/journal.pmed.1002344","article-title":"Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action","volume":"14","author":"T Wi","year":"2017","journal-title":"PLOS Med"},{"key":"pone.0237424.ref039","article-title":"Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea","author":"M Unemo","year":"2012","journal-title":"Future Microbiology"},{"issue":"7","key":"pone.0237424.ref040","doi-asserted-by":"crossref","first-page":"e1002366","DOI":"10.1371\/journal.pmed.1002366","article-title":"Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines","volume":"14","author":"E Alirol","year":"2017","journal-title":"PLoS Med"},{"key":"pone.0237424.ref041","unstructured":"FDA. Target Product Profile\u2014A Strategic Development Process Tool | FDA [Internet]. 2007 [cited 2019 Aug 5]. Available from: https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/target-product-profile-strategic-development-process-tool"},{"issue":"3","key":"pone.0237424.ref042","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1128\/AAC.05760-11","article-title":"High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure","volume":"56","author":"M Unemo","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"issue":"25","key":"pone.0237424.ref043","doi-asserted-by":"crossref","first-page":"2504","DOI":"10.1056\/NEJMc1512757","article-title":"Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea","volume":"374","author":"H Fifer","year":"2016","journal-title":"N Engl J Med"},{"issue":"1","key":"pone.0237424.ref044","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1128\/AAC.49.1.137-143.2005","article-title":"Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan","volume":"49","author":"M Ito","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"pone.0237424.ref045","article-title":"Acceptability and Feasibility of Integrating Point-of-Care Diagnostic Testing of Sexually Transmitted Infections into a South African Antenatal Care Program for HIV-Infected Pregnant Women","author":"E Morikawa","year":"2018","journal-title":"Infect Dis Obstet Gynecol"},{"issue":"6","key":"pone.0237424.ref046","doi-asserted-by":"crossref","first-page":"e015447","DOI":"10.1136\/bmjopen-2016-015447","article-title":"Analysis of the potential for point-of-care test to enable individualised treatment of infections caused by antimicrobial-resistant and susceptible strains of Neisseria gonorrhoeae: a modelling study","volume":"7","author":"KM Turner","year":"2017","journal-title":"BMJ Open"},{"key":"pone.0237424.ref047","article-title":"Point-of-care tests for STIs: the way forward","volume":"93","author":"I Toskin","year":"2017","journal-title":"Sex Transm Infect"},{"key":"pone.0237424.ref048","article-title":"The performance of the vaginal discharge syndromic management in treating vaginal and cervical infection: A systematic review and meta-analysis","author":"C Zemouri","year":"2016","journal-title":"PLoS ONE"},{"issue":"9","key":"pone.0237424.ref049","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.ajem.2015.06.009","article-title":"Overtreatment of gonorrhea and chlamydial infections in 2 inner-city emergency departments","volume":"33","author":"CE Holley","year":"2015","journal-title":"Am J Emerg Med"},{"key":"pone.0237424.ref050","volume-title":"Global strategy for the prevention and control of sexually transmitted infections: 2006\u20132015","author":"WHO","year":"2018"},{"issue":"9","key":"pone.0237424.ref051","doi-asserted-by":"crossref","first-page":"e1001306","DOI":"10.1371\/journal.pmed.1001306","article-title":"Point-of-Care Testing for Infectious Diseases: Diversity, Complexity, and Barriers in Low- And Middle-Income Countries","volume":"9","author":"NP Pai","year":"2012","journal-title":"PLoS Med"},{"issue":"5","key":"pone.0237424.ref052","doi-asserted-by":"crossref","first-page":"e257","DOI":"10.1016\/S2214-109X(15)70089-6","article-title":"Point-of-care diagnostic tests for low-resource settings","volume":"3","author":"PJ Garcia","year":"2015","journal-title":"Lancet Glob Heal"},{"issue":"5","key":"pone.0237424.ref053","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1136\/sti.79.5.363","article-title":"Sensitivity requirements for the point of care diagnosis of Chlamydia trachomatis and Neisseria gonorrhoeae in women","volume":"79","author":"P Vickerman","year":"2003","journal-title":"Sex Transm Infect"},{"key":"pone.0237424.ref054","unstructured":"Rosser E, Leslie Lugo M, Harvey SA, Cullen Balogun T, Barbu S, Beals J, et al. Willingness to Use and Pay for New Diagnostic Tests for Six Priority Diseases: Results from India [Internet]. [cited 2019 Jan 21]. Available from: www.chs-urc.org"},{"issue":"2","key":"pone.0237424.ref055","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.diagmicrobio.2016.10.019","article-title":"Impact of rapid diagnostic testing for chlamydia and gonorrhea on appropriate antimicrobial utilization in the emergency department","volume":"87","author":"KR Rivard","year":"2017","journal-title":"Diagn Microbiol Infect Dis"},{"key":"pone.0237424.ref056","unstructured":"WHO STI POCT meeting report [Internet]. 2014 [cited 2019 Aug 5]. Available from: https:\/\/www.who.int\/reproductivehealth\/POTC-TPPs-2016.pdf?ua=1"},{"key":"pone.0237424.ref057","unstructured":"Sexually Transmitted and Other Reproductive Tract Infections A guide to essential practice. 2005."},{"issue":"S6","key":"pone.0237424.ref058","article-title":"Diagnosing sexually transmitted infections in resource\u2010constrained settings: challenges and ways forward","volume":"22","author":"TE Wi","year":"2019","journal-title":"J Int AIDS Soc"},{"issue":"11","key":"pone.0237424.ref059","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1128\/JCM.00855-17","article-title":"Multiplex Real-Time PCR Assay for Simultaneous Identification of Neisseria gonorrhoeae and Its Ciprofloxacin Susceptibility Status","volume":"55","author":"SR Perera","year":"2017","journal-title":"J Clin Microbiol"},{"issue":"9","key":"pone.0237424.ref060","article-title":"Implementation of a rapid genotypic assay to promote targeted ciprofloxacin therapy of neisseria gonorrhoeae in a large health system","volume":"64","author":"LT Allan-Blitz","year":"2017","journal-title":"Clin Infect Dis"},{"issue":"6","key":"pone.0237424.ref061","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1093\/jac\/dkz054","article-title":"Genome-based epidemiology and antimicrobial resistance determinants of Neisseria gonorrhoeae isolates with decreased susceptibility and resistance to extended-spectrum cephalosporins in Argentina in 2011\u201316","volume":"74","author":"RA Gianecini","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"pone.0237424.ref062","article-title":"Addressing Barriers to the Development and Adoption of Rapid Diagnostic Tests in Global Health","author":"E Miller","year":"2015","journal-title":"Nanobiomedicine"},{"key":"pone.0237424.ref063","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s12936-016-1174-0","article-title":"Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study","volume":"15","author":"NY Boadu","year":"2016","journal-title":"Malar J"},{"issue":"3","key":"pone.0237424.ref064","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/POC.0000000000000056","article-title":"Barriers to Implementation of Rapid and Point-of-Care Tests for Human Immunodeficiency Virus Infection: Findings From a Systematic Review (1996\u20132014)","volume":"14","author":"NP Pai","year":"2015","journal-title":"Point Care"},{"issue":"1","key":"pone.0237424.ref065","doi-asserted-by":"crossref","first-page":"e0170773","DOI":"10.1371\/journal.pone.0170773","article-title":"Costing of National STI Program Implementation for the Global STI Control Strategy for the Health Sector, 2016\u20132021","volume":"12","author":"EL Korenromp","year":"2017","journal-title":"PLoS One"},{"issue":"Suppl(S1)","key":"pone.0237424.ref066","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/nature05448","article-title":"Requirements for high impact diagnostics in the developing world","volume":"444","author":"M Urdea","year":"2006","journal-title":"Nature"},{"issue":"1","key":"pone.0237424.ref067","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1186\/s12889-015-1577-9","article-title":"The HIV epidemic and sexual and reproductive health policy integration: views of South African policymakers","volume":"15","author":"D Cooper","year":"2015","journal-title":"BMC Public Health"},{"issue":"Suppl 2","key":"pone.0237424.ref068","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1177\/00333549071220S218","article-title":"Advancing Integration of HIV, STD, and Viral Hepatitis Services: State Perspectives","volume":"122","author":"P Whiticar","year":"2007","journal-title":"Public Health Rep"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0237424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T11:28:42Z","timestamp":1617103722000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0237424"}},"subtitle":[],"editor":[{"given":"Cedric","family":"Yansouni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":68,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,9,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0237424","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,1]]}}}