{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:20:48Z","timestamp":1783689648542,"version":"3.55.0"},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T00:00:00Z","timestamp":1601942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0240155","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T17:38:42Z","timestamp":1602005922000},"page":"e0240155","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["National pharmacological treatment trends for ankylosing spondylitis in South Korea: A national health insurance database study"],"prefix":"10.1371","volume":"15","author":[{"given":"Jin-Sung","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4948-4539","authenticated-orcid":true,"given":"Jae-Young","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hak-Kyu","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bongmo","family":"Koo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Hee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Chol","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,10,6]]},"reference":[{"issue":"9570","key":"pone.0240155.ref001","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/S0140-6736(07)60635-7","article-title":"Ankylosing spondylitis","volume":"369","author":"J Braun","year":"2007","journal-title":"Lancet"},{"key":"pone.0240155.ref002","volume-title":"StatPearls","author":"KJ Wenker","year":"2017"},{"issue":"suppl 3","key":"pone.0240155.ref003","doi-asserted-by":"crossref","first-page":"iii8","DOI":"10.1136\/ard.61.suppl_3.iii8","article-title":"Ankylosing spondylitis: an overview","volume":"61","author":"J Sieper","year":"2002","journal-title":"Annals of the Rheumatic Diseases"},{"issue":"4","key":"pone.0240155.ref004","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/rheumatology\/ket387","article-title":"Global prevalence of ankylosing spondylitis","volume":"53","author":"LE Dean","year":"2014","journal-title":"Rheumatology (Oxford)"},{"key":"pone.0240155.ref005","first-page":"4","article-title":"The burden of ankylosing spondylitis","volume":"78","author":"A Boonen","year":"2006","journal-title":"J Rheumatol Suppl"},{"key":"pone.0240155.ref006","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s13075-015-0627-0","article-title":"The prevalence of clinically diagnosed ankylosing spondylitis and its clinical manifestations: a nationwide register study","volume":"17","author":"S Exarchou","year":"2015","journal-title":"Arthritis Res Ther"},{"issue":"5","key":"pone.0240155.ref007","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/s11926-008-0060-3","article-title":"Are spondyloarthropathies as common as rheumatoid arthritis worldwide? A review","volume":"10","author":"N Akkoc","year":"2008","journal-title":"Current rheumatology reports"},{"issue":"4","key":"pone.0240155.ref008","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1002\/art.23275","article-title":"Benefits and risks of ankylosing spondylitis treatment with nonsteroidal antiinflammatory drugs","volume":"58","author":"IH Song","year":"2008","journal-title":"Arthritis Rheum"},{"issue":"6","key":"pone.0240155.ref009","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1136\/ard.2011.151027","article-title":"2010 update of the ASAS\/EULAR recommendations for the management of ankylosing spondylitis","volume":"70","author":"J Braun","year":"2011","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"pone.0240155.ref010","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/rheumatology\/35.8.767","article-title":"Assessment of the efficacy of sacroiliac corticosteroid injections in spondylarthropathies: a double-blind study","volume":"35","author":"Y Maugars","year":"1996","journal-title":"Br J Rheumatol"},{"issue":"6","key":"pone.0240155.ref011","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1136\/annrheumdis-2014-205322","article-title":"Efficacy of TNFalpha blockers in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a meta-analysis","volume":"74","author":"J Callhoff","year":"2015","journal-title":"Ann Rheum Dis"},{"issue":"4","key":"pone.0240155.ref012","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00002281-200107000-00001","article-title":"New treatment options in spondyloarthropathies: increasing evidence for significant efficacy of anti-tumor necrosis factor therapy","volume":"13","author":"J Braun","year":"2001","journal-title":"Curr Opin Rheumatol"},{"issue":"4","key":"pone.0240155.ref013","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/art.1780270401","article-title":"Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria","volume":"27","author":"S van der Linden","year":"1984","journal-title":"Arthritis Rheum"},{"issue":"6","key":"pone.0240155.ref014","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1002\/art.30225","article-title":"Sulfasalazine for the treatment of ankylosing spondylitis: relic or niche medication?","volume":"63","author":"MM Ward","year":"2011","journal-title":"Arthritis Rheum"},{"issue":"3","key":"pone.0240155.ref015","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1080\/03009740510026599","article-title":"Therapy of ankylosing spondylitis. Part II: biological therapies in the spondyloarthritides","volume":"34","author":"J Braun","year":"2005","journal-title":"Scand J Rheumatol"},{"issue":"2","key":"pone.0240155.ref016","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1002\/art.20852","article-title":"Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT)","volume":"52","author":"D van der Heijde","year":"2005","journal-title":"Arthritis Rheum"},{"issue":"3","key":"pone.0240155.ref017","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/ard.2006.054098","article-title":"No efficacy of subcutaneous methotrexate in active ankylosing spondylitis: a 16-week open-label trial","volume":"66","author":"H Haibel","year":"2007","journal-title":"Ann Rheum Dis"},{"issue":"8","key":"pone.0240155.ref018","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1093\/rheumatology\/kes066","article-title":"First update of the current evidence for the management of ankylosing spondylitis with non-pharmacological treatment and non-biologic drugs: a systematic literature review for the ASAS\/EULAR management recommendations in ankylosing spondylitis","volume":"51","author":"R van den Berg","year":"2012","journal-title":"Rheumatology (Oxford)"},{"issue":"1","key":"pone.0240155.ref019","doi-asserted-by":"crossref","first-page":"e000033","DOI":"10.1136\/rmdopen-2014-000033","article-title":"Trends in treatment and outcomes of ankylosing spondylitis in outpatient rheumatological care in Germany between 2000 and 2012","volume":"1","author":"D Huscher","year":"2015","journal-title":"RMD Open"},{"issue":"3","key":"pone.0240155.ref020","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jbspin.2009.11.015","article-title":"Clinical spectrum of ankylosing spondylitis in Korea","volume":"77","author":"TJ Kim","year":"2010","journal-title":"Joint Bone Spine"},{"issue":"2","key":"pone.0240155.ref021","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1002\/path.4187","article-title":"Tumour necrosis factor in infectious disease","volume":"230","author":"JP Waters","year":"2013","journal-title":"J Pathol"},{"issue":"19","key":"pone.0240155.ref022","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1001\/jama.295.19.2275","article-title":"Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials","volume":"295","author":"T Bongartz","year":"2006","journal-title":"JAMA"},{"issue":"4","key":"pone.0240155.ref023","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1007\/s11096-019-00859-7","article-title":"Adverse events in patients with ankylosing spondylitis treated with TNF inhibitors: a cross-sectional study","volume":"41","author":"J Wronski","year":"2019","journal-title":"Int J Clin Pharm"},{"issue":"6","key":"pone.0240155.ref024","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1136\/ard.2011.151563","article-title":"2010 Update of the international ASAS recommendations for the use of anti-TNF agents in patients with axial spondyloarthritis","volume":"70","author":"D van der Heijde","year":"2011","journal-title":"Ann Rheum Dis"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0240155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T17:38:59Z","timestamp":1602005939000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0240155"}},"subtitle":[],"editor":[{"given":"Omid","family":"Beiki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,10,6]]},"references-count":24,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0240155","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,6]]}}}