{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:01:11Z","timestamp":1787022071229,"version":"build-2736575974"},"reference-count":15,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T00:00:00Z","timestamp":1602547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004861","name":"Mackay Memorial Hospital","doi-asserted-by":"publisher","award":["MMH-107- 76"],"award-info":[{"award-number":["MMH-107- 76"]}],"id":[{"id":"10.13039\/501100004861","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0240445","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T13:41:51Z","timestamp":1602596511000},"page":"e0240445","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Relationship between serum gamma-glutamyl transferase level and colorectal adenoma"],"prefix":"10.1371","volume":"15","author":[{"given":"Tzu-Chan","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Chih","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Horng","family":"Kao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Jen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Jen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horng-Yuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang-Che","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lo-Yip","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7127-4015","authenticated-orcid":true,"given":"Kuang-Chun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,10,13]]},"reference":[{"issue":"8058","key":"pone.0240445.ref001","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0140-6736(78)90487-7","article-title":"Aetiology of adenoma\u2014carcinoma sequence in large bowel","volume":"1","author":"MJ Hill","year":"1978","journal-title":"Lancet"},{"issue":"9927","key":"pone.0240445.ref002","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/S0140-6736(13)61649-9","article-title":"Colorectal cancer","volume":"383","author":"H Brenner","year":"2014","journal-title":"Lancet"},{"issue":"1","key":"pone.0240445.ref003","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1053\/j.gastro.2017.05.013","article-title":"Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer","volume":"153","author":"DK Rex","year":"2017","journal-title":"Gastroenterology"},{"key":"pone.0240445.ref004","doi-asserted-by":"crossref","first-page":"818570","DOI":"10.1155\/2015\/818570","article-title":"Gamma-Glutamyltransferase: A Predictive Biomarker of Cellular Antioxidant Inadequacy and Disease Risk","volume":"2015","author":"G Koenig","year":"2015","journal-title":"Dis Markers"},{"issue":"4","key":"pone.0240445.ref005","first-page":"1169","article-title":"Gamma-glutamyltransferase of cancer cells at the crossroads of tumor progression, drug resistance and drug targeting","volume":"30","author":"A Corti","year":"2010","journal-title":"Anticancer Res"},{"issue":"8","key":"pone.0240445.ref006","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1002\/ijc.23714","article-title":"Prospective study of the association of gamma-glutamyltransferase with cancer incidence in women","volume":"123","author":"AM Strasak","year":"2008","journal-title":"Int J Cancer"},{"issue":"10","key":"pone.0240445.ref007","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.1158\/0008-5472.CAN-07-6686","article-title":"Association of gamma-glutamyltransferase and risk of cancer incidence in men: a prospective study","volume":"68","author":"AM Strasak","year":"2008","journal-title":"Cancer Res"},{"issue":"1","key":"pone.0240445.ref008","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1159\/000369367","article-title":"A pilot study of fluorescent imaging of colorectal tumors using a gamma-glutamyl-transpeptidase-activatable fluorescent probe","volume":"91","author":"C Sato","year":"2015","journal-title":"Digestion"},{"issue":"Supplement 1","key":"pone.0240445.ref009","first-page":"S62","article-title":"Diagnosis and Classification of Diabetes Mellitus","volume":"33","year":"2010","journal-title":"Diabetes Care"},{"issue":"8","key":"pone.0240445.ref010","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1210\/jc.2017-00257","article-title":"Synergistic Effect of Hyperglycemia and Helicobacterpylori Infection Status on Colorectal Adenoma Risk","volume":"102","author":"KC Hu","year":"2017","journal-title":"J Clin Endocrinol Metab"},{"issue":"65","key":"pone.0240445.ref011","doi-asserted-by":"crossref","first-page":"108655","DOI":"10.18632\/oncotarget.22094","article-title":"Hyperglycemia combined Helicobacter pylori infection increases risk of synchronous colorectal adenoma and carotid artery plaque","volume":"8","author":"KC Hu","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"pone.0240445.ref012","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/jso.2930370115","article-title":"Gamma glutamyl transferase activity in rat colon during experimental colonic carcinogenesis","volume":"37","author":"OJ Traynor","year":"1988","journal-title":"J Surg Oncol"},{"issue":"2","key":"pone.0240445.ref013","first-page":"117","article-title":"Gamma glutamyl transpeptidase in colon cancer induced by 1,2-dimethylhydrazine","volume":"47","author":"S Fiala","year":"1977","journal-title":"Arch Geschwulstforsch"},{"issue":"13","key":"pone.0240445.ref014","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1016\/j.ejca.2011.03.010","article-title":"Gamma-glutamyltransferase and risk of cancer in a cohort of 545,460 persons\u2014the Swedish AMORIS study","volume":"47","author":"M Van Hemelrijck","year":"2011","journal-title":"Eur J Cancer"},{"issue":"9","key":"pone.0240445.ref015","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1038\/bjc.2012.128","article-title":"Gamma-glutamyl transferase: risk and prognosis of cancer","volume":"106","author":"IS Fentiman","year":"2012","journal-title":"Br J Cancer"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0240445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T13:42:10Z","timestamp":1602596530000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0240445"}},"subtitle":[],"editor":[{"given":"Xianwu","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,10,13]]},"references-count":15,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020,10,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0240445","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,13]]}}}