{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T14:12:44Z","timestamp":1782742364383,"version":"3.54.5"},"reference-count":40,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jiangsu Province\u2019s Key Provincial Talents Program","award":["ZDRCA2016046"],"award-info":[{"award-number":["ZDRCA2016046"]}]},{"name":"Key Health Talents in Gusu","award":["GSWS2019009"],"award-info":[{"award-number":["GSWS2019009"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Coronavirus disease 2019 (COVID-19) has spread to the world. Whether there is an association between lifestyle behaviors and the acquisition of COVID-19 remains unclear.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>In this case-control study, we recruited 105 patients with SARS-CoV-2 infection as a case group from the Wuhan Tongji Hospital (Wuhan, China). For each case two control subjects were recruited. Participants were randomly selected from communities in Wuhan and matched for sex, age (\u00b1 2yrs), and pre-existing comorbidities (hypertension and diabetes).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 105 patients diagnosed with COVID-19 and 210 controls were included. Compared with control group, the case group had higher proportions of lack of sleep (30.5% vs. 14.8%, P = 0.001) and increased physical activities (56.2% vs. 32.9%, P &lt; 0.001). And patients in the case group were more likely to have alopecia (28.6% vs. 10.0%, P &lt; 0.001) than people from the control group. Overall, we found that lack of sleep [adjusted odds ratio (OR) 1.56, 95% confidence interval (CI) 1.03\u20132.39)], physical activities (\u2265 5 times a week) (adjusted OR 2.05, 95%CI 1.39\u20133.02) and alopecia (adjusted OR 1.73, 95%CI 1.13\u20132.66) were independent risk factors for COVID-19 infection. Conversely, low-dose alcohol intake (&lt;100g alcohol per week), hand hygiene, and fruits intake (daily) were significantly associated with a decrease in morbidity.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Individual lifestyle behaviors and health status can affect the occurrence of COVID-19.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0241540","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T18:27:53Z","timestamp":1604600873000},"page":"e0241540","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["The impact of individual lifestyle and status on the acquisition of COVID-19: A case\u2014Control 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