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Detection is both crucial and challenging, especially in languages with transparent orthographies, such as Spanish. To make detecting dyslexia easier, we designed an online gamified test and a predictive machine learning model. In a study with more than 3,600 participants, our model correctly detected over 80% of the participants with dyslexia. To check the robustness of the method we tested our method using a new data set with over 1,300 participants with age customized tests in a different environment -a tablet instead of a desktop computer- reaching a recall of over 78% for the class with dyslexia for children 12 years old or older. Our work shows that dyslexia can be screened using a machine learning approach. An online screening tool in Spanish based on our methods has already been used by more than 200,000 people.<\/jats:p>","DOI":"10.1371\/journal.pone.0241687","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T18:35:44Z","timestamp":1606934144000},"page":"e0241687","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":67,"title":["Predicting risk of dyslexia with an online gamified test"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0886-026X","authenticated-orcid":true,"given":"Luz","family":"Rello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Baeza-Yates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey P.","family":"Bigham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miquel","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,12,2]]},"reference":[{"issue":"1","key":"pone.0241687.ref001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11881-003-0001-9","article-title":"A definition of dyslexia","volume":"53","author":"GR Lyon","year":"2003","journal-title":"Annals of Dyslexia"},{"issue":"3","key":"pone.0241687.ref002","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.neuroimage.2010.10.062","article-title":"Gray matter volume changes following reading intervention in dyslexic children","volume":"57","author":"AJ Krafnick","year":"2011","journal-title":"Neuroimage"},{"issue":"5938","key":"pone.0241687.ref003","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1126\/science.1171999","article-title":"Dyslexia: a new synergy between education and cognitive neuroscience","volume":"325","author":"JD Gabrieli","year":"2009","journal-title":"Science"},{"issue":"3","key":"pone.0241687.ref004","doi-asserted-by":"crossref","first-page":"269","DOI":"10.12816\/0003139","article-title":"Dyslexia: Its impact on the Individual, Parents and Society","volume":"12","author":"L Al-Lamki","year":"2012","journal-title":"Sultan Qaboos University medical journal"},{"issue":"1","key":"pone.0241687.ref005","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1046\/j.0021-9630.2003.00305.x","article-title":"Specific reading disability (dyslexia): What have we learned in the past four decades?","volume":"45","author":"FR Vellutino","year":"2004","journal-title":"Journal of Child Psychology and Psychiatry"},{"key":"pone.0241687.ref006","doi-asserted-by":"crossref","first-page":"131","DOI":"10.4324\/9780203858462","volume-title":"Reading and dyslexia in different orthographies","author":"N Brunswick","year":"2010"},{"key":"pone.0241687.ref007","volume-title":"PROLEC-R. 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