{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T11:30:36Z","timestamp":1777980636089,"version":"3.51.4"},"reference-count":65,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T00:00:00Z","timestamp":1606867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell\u2019Istruzione, dell\u2019Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["2015WPHSCJ"],"award-info":[{"award-number":["2015WPHSCJ"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The Neanderthal specimen from Lamalunga Cave, near Altamura (Apulia, Italy), was discovered during a speleological survey in 1993. The specimen is one of the most complete fossil hominins in Europe and its state of preservation is exceptional, although it is stuck in calcareous concretions and the bones are mostly covered by calcite depositions. Nevertheless, it is possible to carry out some observations on craniodental features that have not previously been described. In this work, we present an account of the oral cavity, made possible by the use of a videoscope, which allowed us to reach some hidden parts of the mandible and palate. This is the first detailed overview of the teeth and maxillary bones of the Neanderthal skeleton from Altamura. The dentition is almost complete. However, two teeth (upper right P3 and upper left M1) were lost<jats:italic>ante mortem<\/jats:italic>and four teeth (lower right I1 and P3 and lower left I1 and I2) were lost most probably<jats:italic>post mortem<\/jats:italic>. Dental wear is marked. The erupted M3s and the inversion of the compensating curve of Wilson in the M1s and M2s but not in the M3s suggest that the individual is fully adult, but not old. Although most of the teeth have their roots exposed for several millimeters, the periodontal bone appears to be in good condition overall, except in correspondence of the two<jats:italic>ante-mortem<\/jats:italic>tooth losses. X-rays of the anterior teeth show a periapical lesion, probably linked to the advanced dental wear. We also observed a weak expression of taurodontism in the posterior dentition and the presence of a retromolar space, features consistent with an attribution to the Neanderthal hypodigm; this attribution is also supported by aspects of the cranial morphology, the morphometric analysis of the scapula and preliminary mtDNA data. There is also a well-developed palatine torus, to the best of our knowledge a feature not previously described in Neanderthals.<\/jats:p>","DOI":"10.1371\/journal.pone.0241713","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T18:23:59Z","timestamp":1606933439000},"page":"e0241713","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["In situ observations on the dentition and oral cavity of the Neanderthal skeleton from Altamura (Italy)"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7240-0009","authenticated-orcid":true,"given":"Alessandro","family":"Riga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Boggioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Papini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8951-2990","authenticated-orcid":true,"given":"Costantino","family":"Buzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Profico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Di Vincenzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damiano","family":"Marchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5055-8369","authenticated-orcid":true,"given":"Jacopo","family":"Moggi-Cecchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Manzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2020,12,2]]},"reference":[{"key":"pone.0241713.ref001","first-page":"249","article-title":"An archaic human skeleton discovered at Altamura (Bari, Italy)","volume":"71","author":"V Pesce Delfino","year":"1993","journal-title":"Riv Antropol"},{"key":"pone.0241713.ref002","first-page":"17","article-title":"Lineamenti geomorfologici della Grotta di Lamalunga","volume":"2","author":"S Agostini","year":"2011","journal-title":"DiRE in Puglia"},{"key":"pone.0241713.ref003","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jhevol.2015.02.007","article-title":"The Neanderthal in the karst: First dating, morphometric, and paleogenetic data on the fossil skeleton from Altamura (Italy)","volume":"82","author":"M Lari","year":"2015","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref004","first-page":"113","article-title":"Three-dimensional topographic survey of the human remains in Lamalunga cave (Altamura, Bari, Southern Italy)","volume":"28","author":"E Vacca","year":"2004","journal-title":"Coll Antropol."},{"key":"pone.0241713.ref005","first-page":"27","article-title":"Lo scheletro umano e i reperti faunistici della grotta di Lamalunga: considerazioni tafonomiche","volume":"2","author":"G Giacobini","year":"2010","journal-title":"DiRE in 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(Europe)","author":"JH Schwartz","year":"2002"},{"key":"pone.0241713.ref010","volume-title":"Doctoral dissertation","author":"Washington University in St. Louis","year":"2014"},{"key":"pone.0241713.ref011","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jhevol.2015.10.011","article-title":"Comparative perspective on antemortem tooth loss in Neandertals","volume":"92","author":"CG Gilmore","year":"2016","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref012","author":"BKB Berkovitz","year":"2011","journal-title":"Oral biologyLondon: Churchill-Livingstone"},{"key":"pone.0241713.ref013","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1902\/jop.1941.12.2.71","article-title":"Progress of gingival inflammation into the supporting structures of the teeth","volume":"12","author":"JP Weinmann","year":"1941","journal-title":"J Periodontol"},{"key":"pone.0241713.ref014","first-page":"241","volume-title":"Advances in dental anthropology","author":"NG Clarke","year":"1991"},{"key":"pone.0241713.ref015","first-page":"283","volume-title":"Advances in human palaeopathology.\u200e","author":"A Ogden","year":"2008"},{"key":"pone.0241713.ref016","first-page":"67","article-title":"A method of assessing periodontal status in archaeologically derived skeletal material","volume":"2","author":"NW Kerr","year":"1988","journal-title":"J Paleopathol"},{"key":"pone.0241713.ref017","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1600-0765.1991.tb02073.x","article-title":"Prevalence and natural history of periodontal disease in Scotland\u2013The mediaeval period (900\u20131600 A.D.)","volume":"26","author":"NW Kerr","year":"1991","journal-title":"J Periodont Res"},{"key":"pone.0241713.ref018","first-page":"261","volume-title":"Reconstruction of life from the skeleton","author":"JR Lukacs","year":"1989"},{"key":"pone.0241713.ref019","doi-asserted-by":"crossref","first-page":"42","DOI":"10.5005\/jp-journals-10042-1034","article-title":"A comprehensive review on dental calculus","volume":"7","author":"S Aghanashini","year":"2016","journal-title":"J Health Sci Res"},{"key":"pone.0241713.ref020","first-page":"476","article-title":"Taurodont teeth in South African races","volume":"62","author":"JCM Shaw","year":"1928","journal-title":"J Anat"},{"key":"pone.0241713.ref021","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ajpa.1330680105","article-title":"Dental wear in the Libben population: its functional pattern and role in the determination of adult skeletal age at death","volume":"68","author":"CO Lovejoy","year":"1985","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref022","doi-asserted-by":"crossref","first-page":"e14769","DOI":"10.1371\/journal.pone.0014769","article-title":"Molar macrowear reveals Neanderthal eco-geographic dietary variation","volume":"6","author":"L Fiorenza","year":"2011","journal-title":"Plos One"},{"key":"pone.0241713.ref023","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/ajpa.1330340204","article-title":"Human tooth wear, tooth function and cultural variability","volume":"34","author":"S Molnar","year":"1971","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref024","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1086\/203686","article-title":"Interproximal grooving of teeth: additional evidence and interpretation","volume":"29","author":"V Formicola","year":"1988","journal-title":"Curr Anthropol"},{"key":"pone.0241713.ref025","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jhevol.2014.07.007","article-title":"Division of labor by sex and age in Neanderthals: an approach through the study of activity-related dental wear","volume":"80","author":"A Estallrich","year":"2015","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref026","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/ajpa.1330630107","article-title":"Patterns of molar wear in hunter-gatherers and agriculturalists","volume":"63","author":"BH Smith","year":"1984","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref027","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1002\/ajpa.1330920108","article-title":"Orientation of the masseter muscle and the curve of Spee in relation to crushing forces on the molar teeth of primates","volume":"92","author":"JW Osborn","year":"1993","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref028","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ajpa.10329","article-title":"Tooth wear and the \u201cdesign\u201d of human dentition: a perspective from evolutionary medicine","volume":"46","author":"Y Kaifu","year":"2003","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref029","doi-asserted-by":"crossref","first-page":"e547","DOI":"10.4317\/medoral.18291","article-title":"Wilson maxillary curve analyzed by CBCT. A study on normocclusion and malocclusion individuals","volume":"18","author":"J-M Barrera","year":"2013","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"pone.0241713.ref030","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.ajodo.2006.10.037","article-title":"Development of the curve of Spee","volume":"134","author":"SD Marshall","year":"2008","journal-title":"Am J Orthod Dentofac Orthop"},{"key":"pone.0241713.ref031","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0889-5406(96)70110-5","article-title":"The curve of Spee revisited","volume":"110","author":"S Braun","year":"1996","journal-title":"Am J Orthod Dentofac Orthop"},{"key":"pone.0241713.ref032","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/ajpa.1330530202","article-title":"The natural history of the helicoidal occlusal plane and its evolution in early Homo","volume":"53","author":"PV Tobias","year":"1980","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref033","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/ajpa.1330570305","article-title":"Helicoidal plane of dental occlusion","volume":"57","author":"JW Osborn","year":"1982","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref034","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/BF02436615","article-title":"Development of the helicoidal plane","volume":"1","author":"LC Richards","year":"1986","journal-title":"Hum Evol"},{"issue":"1\u20132","key":"pone.0241713.ref035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13219-013-0089-3","article-title":"Oral exostoses: an assessment of two hundred years of research","volume":"26","author":"A L\u00e9onard","year":"2014","journal-title":"Bull M\u00e9m Soc Anthropol Paris"},{"key":"pone.0241713.ref036","article-title":"Human tooth crown and root morphology: the Arizona State University dental anthropology system","author":"GR Scott","year":"2017","journal-title":"New York: Cambridge University Press"},{"key":"pone.0241713.ref037","first-page":"112","article-title":"Nouvelles recherches sur l\u2019homme fossile de Chancelade","author":"HV Vallois","year":"1939","journal-title":"Congr. Internat. Sci. Anthrop. Ethnol., C. R. 2me. Sess"},{"key":"pone.0241713.ref038","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/ajpa.1330360207","article-title":"Torus palatinus in the Neanderthal Circeo I skull. A histologic, microradiographic and electron microscopic investigation","volume":"36","author":"S Sergi","year":"1972","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref039","doi-asserted-by":"crossref","DOI":"10.1002\/0471722715","volume-title":"The human fossil record. Volume two. Craniodental morphology of genus Homo (Africa and Asia)","author":"JH Schwartz","year":"2003"},{"key":"pone.0241713.ref040","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1006\/jhev.1996.0040","article-title":"Hauser G. Developmental stress and cranial hypostosis by epigenetic trait occurence and distribution: an exploratory study on the Italian Neandertals","volume":"30","author":"G Manzi","year":"1996","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref041","first-page":"97","article-title":"Die Kronen und Wurzeln der Mahlz\u00e4hne des Homo primigenius und ihre genetische Bedeutung.","volume":"31","author":"D Gorjianovi\u0107-Kramberger","year":"1907","journal-title":"Anat Anz"},{"key":"pone.0241713.ref042","first-page":"401","article-title":"\u00dcber prismatische Molarwurzeln rezent er und diluvialer Menschen","volume":"32","author":"D Gorjianovi\u0107-Kramberger","year":"1908","journal-title":"Anat Anz"},{"key":"pone.0241713.ref043","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.jhevol.2010.05.009","article-title":"Mandibular molar root morphology in Neanderthals and Late Pleistocene and recent Homo sapiens","volume":"59","author":"K Kupczik","year":"2010","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref044","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/joa.12260","article-title":"Exploring the biomechanics of taurodontism","volume":"226","author":"S Benazzi","year":"2015","journal-title":"J Anat"},{"key":"pone.0241713.ref045","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1006\/jhev.1995.1043","article-title":"Determinants of retromolar space presence in Pleistocene Homo mandibles","volume":"28","author":"RG Franciscus","year":"1995","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref046","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1002\/oa.2451","article-title":"The retromolar space: a morphological curiosity observed amongst the protohistoric Arikara and Mandan","volume":"26","author":"C De la Cova","year":"2016","journal-title":"Int J Osteoarchaeol"},{"key":"pone.0241713.ref047","author":"CS Coon","year":"1962"},{"key":"pone.0241713.ref048","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1515\/9783110810691.389","volume-title":"Paleoanthropology: Morphology and paleoecology","author":"WW Howells","year":"1975"},{"key":"pone.0241713.ref049","volume-title":"The Shanidar Neanderthals","author":"E Trinkaus","year":"1983"},{"key":"pone.0241713.ref050","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/0047-2484(87)90071-6","article-title":"The Neanderthal face: evolutionary and functional perspectives on a recent hominid face","volume":"16","author":"E Trinkaus","year":"1987","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref051","first-page":"9","article-title":"Evolution at the European edge: Neanderthal and Upper Paleolithic relationships","volume":"2","author":"DW Frayer","year":"1992","journal-title":"Pr\u00e9hist Europ"},{"key":"pone.0241713.ref052","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/ar.a.20049","article-title":"Geometric morphometric analysis of allometric variation in the mandibular morphology from the hominids of Atapuerca, Sima de los Huesos site","volume":"278A","author":"A Rosas","year":"2004","journal-title":"Anat Rec"},{"key":"pone.0241713.ref053","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ajpa.1330910102","article-title":"Biomechanical analysis of masticatory system configuration in Neanderthals and Inuits","volume":"91","author":"MA Spencer","year":"1993","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref054","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.jhevol.2011.11.014","article-title":"Tooth wear, Neanderthal facial morphology and the anterior dental loading hypothesis","volume":"62","author":"AF Clement","year":"2012","journal-title":"J Hum Evol"},{"key":"pone.0241713.ref055","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/1096-8644(200101)114:1<74::AID-AJPA1007>3.0.CO;2-U","article-title":"Occurrence of Neanderthal features in mandibles from the Atapuerca-SH site","volume":"114","author":"A Rosas","year":"2001","journal-title":"Am J Phys Anthropol"},{"key":"pone.0241713.ref056","first-page":"1","volume":"35","author":"JL Heim","year":"1976","journal-title":"Arch Inst Pal\u00e9ontol Hum"},{"key":"pone.0241713.ref057","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ajpa.1330670105","article-title":"Pathology and the posture of the La Chapelle-aux-Saints Neandertal","volume":"67","author":"E Trinkaus","year":"1985","journal-title":"Am J Phys Anthropol"},{"issue":"51","key":"pone.0241713.ref058","doi-asserted-by":"crossref","first-page":"19266","DOI":"10.1073\/pnas.0609662104","article-title":"Paleobiology and comparative morphology of a late Neandertal sample from El Sidr\u00f3n, Asturias, Spain","volume":"103","author":"A Rosas","year":"2006","journal-title":"Proc Natl Acad Sci"},{"key":"pone.0241713.ref059","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1177\/0022034510387797","article-title":"New evidence of dental pathology in 40,000-year-old Neandertals","volume":"90","author":"MJ Walker","year":"2011","journal-title":"J Dent Res"},{"key":"pone.0241713.ref060","first-page":"6359","article-title":"Oral pathology in the Iberian Neanderthals","volume":"11","author":"A L\u00f3pez Valverde","year":"2012","journal-title":"Afr J Biotechnol"},{"key":"pone.0241713.ref061","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.jhevol.2011.08.007","article-title":"Morphological description and comparison of the dental remains from Atapuerca-Sima de los Huesos site (Spain)","volume":"62","author":"M Martin\u00f3n-Torres","year":"2012","journal-title":"J Hum 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