{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T01:09:06Z","timestamp":1782349746191,"version":"3.54.5"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T00:00:00Z","timestamp":1605830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001146","name":"Greenwall Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001146","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\"><jats:title>Background<\/jats:title><jats:p>Complementary and alternative medicine (CAM) is increasingly being integrated into conventional medical care for cancer, used to counter the side effects of conventional cancer treatment, and offered as an alternative to conventional cancer care. Our aim is to gain a broader understanding of trends in CAM interventions for cancer and crowdfunding campaigns for these interventions.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Methods<\/jats:title><jats:p>GoFundMe campaigns fundraising for CAM were retrieved through a database of crowdfunding campaign data. Search terms were drawn from two National Institutes of Health lists of CAM cancer interventions and a previous study. Campaigns were excluded that did not match these or related search terms or were initiated outside of June 4<jats:sup>th<\/jats:sup>, 2018 to June 4<jats:sup>th<\/jats:sup>, 2019.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Results<\/jats:title><jats:p>1,396 campaigns were identified from the US (n = 1,037, 73.9%), Canada (n = 165, 11.8%), and the UK (n = 107, 7.7%). Most common cancer types were breast (n = 344, 24.6%), colorectal (n = 131, 9.4%), and brain (n = 98, 7.0%). CAM interventions sought included supplements (n = 422, 30.2%), better nutrition (n = 293, 21.0%), high dose vitamin C (n = 276, 19.8%), naturopathy (n = 226, 16.2%), and cannabis products (n = 211, 15.1%). Mexico (n = 198, 41.9%), and the US (n = 169, 35.7%) were the most common treatment destinations.<\/jats:p><\/jats:sec><jats:sec id=\"sec004\"><jats:title>Conclusions<\/jats:title><jats:p>These findings confirm active and ongoing interest in using crowdfunding platforms to finance CAM cancer interventions. They confirm previous findings that CAM users with cancer tend to have late stage cancers, cancers with high mortality rates, and specific diseases such as breast cancer. These findings can inform targeted responses where facilities engage in misleading marketing practices and the efficacy of interventions is unproven.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0242048","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T19:11:36Z","timestamp":1605899496000},"page":"e0242048","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":29,"title":["Crowdfunding for complementary and alternative medicine: What are cancer patients seeking?"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8236-2923","authenticated-orcid":true,"given":"Jeremy","family":"Snyder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Zenone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Caulfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,11,20]]},"reference":[{"key":"pone.0242048.ref001","unstructured":"National Cancer Institute. Complementary and Alternative Medicine (CAM) [Internet]. National Cancer Institute. 1980 [cited 2020 Mar 4]. Available from: https:\/\/www.cancer.gov\/about-cancer\/treatment\/cam"},{"key":"pone.0242048.ref002","unstructured":"National Health Service. Complementary and alternative medicine [Internet]. nhs.uk. 2018 [cited 2020 Mar 22]. 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Available from: https:\/\/www.cancer.gov\/about-cancer\/treatment\/cam\/patient"},{"key":"pone.0242048.ref006","unstructured":"American Cancer Society. The Truth About Alternative Medical Treatments [Internet]. 2019 [cited 2020 Mar 22]. Available from: https:\/\/www.cancer.org\/latest-news\/the-truth-about-alternative-medical-treatments.html"},{"issue":"10","key":"pone.0242048.ref007","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1001\/jamaoncol.2018.2487","article-title":"Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers","volume":"4","author":"SB Johnson","year":"2018","journal-title":"JAMA Oncol"},{"issue":"1","key":"pone.0242048.ref008","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/jnci\/djx145","article-title":"Use of Alternative Medicine for Cancer and Its Impact on Survival","volume":"110","author":"SB Johnson","year":"2018","journal-title":"J Natl Cancer Inst"},{"issue":"5","key":"pone.0242048.ref009","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1007\/s11764-016-0530-y","article-title":"Complementary and alternative medicine use among US cancer survivors","volume":"10","author":"GM John","year":"2016","journal-title":"J Cancer Surviv"},{"key":"pone.0242048.ref010","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/978-3-030-05855-5_7","volume-title":"Cancer and Society: A Multidisciplinary Assessment and Strategies for Action","author":"DH Gorski","year":"2019"},{"issue":"2","key":"pone.0242048.ref011","article-title":"From Disappointment to Holistic Ideals: A Qualitative Study on Motives and Experiences of Using Complementary and Alternative Medicine in Sweden","volume":"4","author":"J-A Danell","year":"2015","journal-title":"J Public Health Res"},{"issue":"1","key":"pone.0242048.ref012","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s11673-018-9890-5","article-title":"Medicine is Patriarchal, But Alternative Medicine is Not the Answer","volume":"16","author":"A Shahvisi","year":"2019","journal-title":"Bioethical Inquiry"},{"issue":"1","key":"pone.0242048.ref013","doi-asserted-by":"crossref","first-page":"E7","DOI":"10.1188\/10.ONF.E7-E15","article-title":"Gender, Symptom Experience, and Use of Complementary and Alternative Medicine Practices Among Cancer Survivors in the U.S","volume":"37","author":"JM Fouladbakhsh","year":"2010","journal-title":"Cancer Population. Oncology Nursing Forum"},{"key":"pone.0242048.ref014","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ejca.2016.10.029","article-title":"Use of complementary and alternative medicine: A multicenter cross-sectional study in 1089 melanoma patients","volume":"71","author":"C Loquai","year":"2017","journal-title":"European Journal of Cancer"},{"key":"pone.0242048.ref015","first-page":"362","article-title":"Is cancer fundraising fuelling quackery?","author":"M Newman","year":"2018","journal-title":"BMJ"},{"issue":"12","key":"pone.0242048.ref016","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1001\/jamainternmed.2019.3330","article-title":"Use of an Online Crowdfunding Platform for Unmet Financial Obligations in Cancer Care","volume":"179","author":"AJ Cohen","year":"2019","journal-title":"JAMA Intern Med"},{"issue":"1","key":"pone.0242048.ref017","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S1470-2045(18)30950-1","article-title":"Patients\u2019 crowdfunding campaigns for alternative cancer treatments","volume":"20","author":"J Snyder","year":"2019","journal-title":"The Lancet Oncology"},{"issue":"18","key":"pone.0242048.ref018","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1001\/jama.2018.3057","article-title":"Crowdfunding for Unproven Stem Cell\u2013Based Interventions","volume":"319","author":"J Snyder","year":"2018","journal-title":"JAMA"},{"issue":"4","key":"pone.0242048.ref019","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2217\/rme-2018-0007","article-title":"Selling stem cell \u2018treatments\u2019 as research: prospective customer perspectives from crowdfunding campaigns","volume":"13","author":"J Snyder","year":"2018","journal-title":"Regenerative Medicine"},{"issue":"16","key":"pone.0242048.ref020","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1001\/jama.2018.10264","article-title":"Medical Crowdfunding for Scientifically Unsupported or Potentially Dangerous Treatments","volume":"320","author":"F Vox","year":"2018","journal-title":"JAMA"},{"issue":"4","key":"pone.0242048.ref021","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1177\/1363459319829194","article-title":"The politics of evidence in online illness narratives: An analysis of crowdfunding for purported stem cell treatments","volume":"23","author":"C Tanner","year":"2019","journal-title":"Health (London)"},{"key":"pone.0242048.ref022","unstructured":"Monroe S by R. When GoFundMe Gets Ugly. The Atlantic [Internet]. [cited 2020 Mar 9]; Available from: https:\/\/www.theatlantic.com\/magazine\/archive\/2019\/11\/gofundme-nation\/598369\/"},{"key":"pone.0242048.ref023","unstructured":"National Cancer Institute. CAM Therapies: A-Z | Health Information | OCCAM [Internet]. [cited 2020 Mar 9]. Available from: https:\/\/cam.cancer.gov\/health_information\/cam_therapies_a-z.htm"},{"key":"pone.0242048.ref024","unstructured":"National Cancer Institute. Categories of CAM Therapies | About CAM | Health Information | OCCAM [Internet]. [cited 2020 Mar 9]. Available from: https:\/\/cam.cancer.gov\/health_information\/categories_of_cam_therapies.htm"},{"issue":"3","key":"pone.0242048.ref025","first-page":"237","article-title":"Complementary and alternative medicine use by glioma patients in Switzerland","volume":"6","author":"G Eisele","year":"2019","journal-title":"Neurooncol Pract"},{"issue":"4","key":"pone.0242048.ref026","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s10552-009-9300-8","article-title":"Socioeconomic differences in lung cancer incidence: a systematic review and meta-analysis","volume":"20","author":"A Sidorchuk","year":"2009","journal-title":"Cancer Causes Control"},{"issue":"7454","key":"pone.0242048.ref027","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1136\/bmj.38111.639734.7C","article-title":"Stigma, shame, and blame experienced by patients with lung cancer: qualitative study","volume":"328","author":"A Chapple","year":"2004","journal-title":"BMJ"},{"issue":"5","key":"pone.0242048.ref028","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/2327-6924.12227","article-title":"Lung Cancer Stigma as a Barrier to Medical Help-Seeking Behavior: Practice Implications","volume":"27","author":"L Carter-Harris","year":"2015","journal-title":"J Am Assoc Nurse Pract"},{"key":"pone.0242048.ref029","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jons.2015.11.010","article-title":"High-dose vitamin C and cancer","volume":"1","author":"A Unlu","year":"2016","journal-title":"Journal of Oncological Science"},{"key":"pone.0242048.ref030","unstructured":"Kreidler M. Tijuana\u2019s Alternative Cancer Treatments: Warnings and Side Effects | Skeptical Inquirer [Internet]. 2017 [cited 2020 Mar 5]. Available from: https:\/\/skepticalinquirer.org\/exclusive\/tijuanas-alternative-cancer-treatments-warnings-and-side-effects\/"},{"key":"pone.0242048.ref031","unstructured":"Coulter M. GoFundMe blocks cash appeals for controversial cancer clinic [Internet]. 2019 [cited 2020 Mar 5]. 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