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Six descending thoracic aortas from pigs were used for rectangular sample tests, in which the circumferential and axial specimens had widths of 6 mm, 8 mm and 10 mm. The other six aortas were used for the dog-bone-shaped sample tests and were punched into circumferential, axial and oblique specimens with widths of 2 mm, 4 mm and 6 mm. We performed uniaxial tensile tests on the specimens and compared the test results. The results showed that mid-sample failure occurred in 85.2% of the dog-bone-shaped specimens and in 11.1% of the rectangular samples, which could be caused by Saint-Venant\u2019s principle. Therefore, rectangular specimens were not suitable for aortic uniaxial tensile testing performed until rupture. The results also showed that the size effect of the aorta conformed to Weibull theory, and dog-bone-shaped specimens with a width of 4 mm were the optimal choice for aortic uniaxial tensile testing performed until rupture.<\/jats:p>","DOI":"10.1371\/journal.pone.0244390","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T22:53:33Z","timestamp":1612824813000},"page":"e0244390","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["The influence of sample geometry and size on porcine aortic material properties from uniaxial tensile tests using custom-designed tissue cutters, clamps and 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