{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T09:43:10Z","timestamp":1782294190573,"version":"3.54.5"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The effect of two microbial phytases at two dose-levels on performance and apparent ileal digestibility (AID) of nutrients in broilers fed European-type diets was studied. A total of 1,200 d-old Ross 308 male broilers were randomly assigned to 5 treatments with 30 birds\/pen and 8 pens\/treatment. A nutritionally adequate positive control (PC) diet was tested against 4 experimental diets containing reduced total P, retainable P, Ca and Na as per the recommended nutritional contribution for <jats:italic>Buttiauxella<\/jats:italic> phytase (Phy B) at 1,000 FTU\/kg (-1.87 g\/kg, -1.59 g\/kg, -1.99 g\/kg and -0.4 g\/kg <jats:italic>vs<\/jats:italic>. PC, respectively). Experimental diets were supplemented with Phy B at 500 FTU\/kg or 1,000 FTU\/kg, or <jats:italic>Citrobacter<\/jats:italic> phytase (Phy C) at 1,000 FTU\/kg or 2,000 FTU\/kg. Diets were based on corn, soybean meal, rapeseed meal and sunflower meal and formulated by phase (starter 1\u201310 d, grower 11\u201321 d) in crumbled or pelleted form. Overall (d 1\u201321), at 1,000 FTU\/kg, birds fed Phy C exhibited lower BWG (-2.7%), FI (-3.4%) and tibia ash (-2.2%) vs. PC (<jats:italic>P<\/jats:italic> &lt; 0.05), and reduced BWG (-3.6%), FI (-3.9%) and tibia ash (-1.8%) vs. Phy B (<jats:italic>P<\/jats:italic> &lt; 0.05). Phy B at 1,000 FTU\/kg and Phy C at 2,000 FTU\/kg maintained performance equivalent to the PC. Digestibility of Ca did not differ among phytase treatments but at 1,000 FTU\/kg AID P was greater with Phy B than Phy C (72.3% vs. 62.7%, <jats:italic>P<\/jats:italic> &lt; 0.05). Ileal phytate (myo-inositol hexakisphosphate, IP6) digestibility was greatest with Phy B at 1,000 FTU\/kg which was higher than Phy C at 1,000 FTU\/kg (87.6 vs. 60.6%, <jats:italic>P<\/jats:italic> &lt; 0.05). The findings indicate a higher phytate degradation rate of Phy B than Phy C at equivalent dose-level and this is correlated to the performance of the broilers.<\/jats:p>","DOI":"10.1371\/journal.pone.0247420","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T19:59:09Z","timestamp":1616702349000},"page":"e0247420","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of two phytases at two doses on performance and phytate degradation in broilers during 1\u201321 days of age"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4984-8999","authenticated-orcid":true,"given":"Yueming","family":"Dersjant-Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2391-4879","authenticated-orcid":true,"given":"Roger","family":"Davin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cees","family":"Kwakernaak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"key":"pone.0247420.ref001","first-page":"125","article-title":"Phytates: occurrence, bioavailability and implications in poultry nutrition","volume":"6","author":"V 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