{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:04:05Z","timestamp":1790193845588,"version":"4.1.0"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>\n                    The characterization of pulmonary arterial hypertension (PAH) relies mainly on right heart catheterization (RHC). Electrical impedance tomography (EIT) provides a non-invasive estimation of lung perfusion that could complement the hemodynamic information from RHC. To assess the association between impedance variation of lung perfusion (\u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    ) and hemodynamic profile, severity, and prognosis, suspected of PAH or worsening PAH patients were submitted simultaneously to RHC and EIT. Measurements of \u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    were obtained. Based on the results of the RHC, 35 patients composed the PAH group, and eight patients, the normopressoric (NP) group. PAH patients showed a significantly reduced \u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    compared to the NP group. There was a significant correlation between \u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    and hemodynamic parameters, particularly with stroke volume (SV) (r = 0.76; P &lt; 0.001). At 60 months, 15 patients died (43%) and 1 received lung transplantation; at baseline they had worse hemodynamics, and reduced \u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    when compared to survivors. Patients with low \u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    (\u2264154.6%.Kg) presented significantly worse survival (P = 0.033). \u0394Z\n                    <jats:sub>Q<\/jats:sub>\n                    is associated with hemodynamic status of PAH patients, with disease severity and survival, demonstrating EIT as a promising tool for monitoring patients with pulmonary vascular disease.\n                  <\/jats:p>","DOI":"10.1371\/journal.pone.0248214","type":"journal-article","created":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T13:48:13Z","timestamp":1615988893000},"page":"e0248214","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Electrical impedance tomography in pulmonary arterial hypertension"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2924-3818","authenticated-orcid":true,"given":"Andr\u00e9 L. 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