{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:21:22Z","timestamp":1792581682505,"version":"4.5.0"},"reference-count":21,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>To compare surgical outcomes between 27 and 25-gauge vitrectomy in proliferative diabetic retinopathy (PDR) with tractional retinal detachment (TRD)<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This retrospective study was conducted to compare the intraoperative status, operation time, use of instruments, endotamponade substance, wound suture number, and iatrogenic break, between 27 and 25-gauge vitrectomy in 43 eyes afflicted by PDR with TRD. The post-surgical results, best-corrected visual acuity, intraocular pressure, recurrent vitreous haemorrhage, and re-operation rate were regularly followed up for 6 months.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Patients in the 25 and the 27-gauge groups did not differ significantly in terms of pre-surgical conditions, such as age, gender, pre-existing glaucoma, best-corrected visual acuity (BCVA) and the severity of their TRD. The mean operation time was 56.7 minutes in the 27-gauge group and 63.7 minutes in the 25-gauge group (p = 0.94). There is significantly less use of micro forceps in the 27-gauge group (p = 0.004). No difference between micro scissors and chandelier usage were noted; neither was their difference in iatrogenic retinal breaks. Significantly fewer wound sutures were noted in the 27-gauge group (p &lt; 0.001). The post-operative results revealed no significant difference in ocular hypertension, hypotony, BCVA improvement, recurrent vitreous haemorrhage and re-operation rate.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The 27-gauge vitrectomy system offers comparable surgical outcomes in PDR with TRD. The 27-gauge vitrectomy system is suitable for complicated retinal surgery.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0249139","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T19:58:08Z","timestamp":1616702288000},"page":"e0249139","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of 27-gauge and 25-gauge vitrectomy in the management of tractional retinal detachment secondary to proliferative diabetic 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Ophthalmol"},{"issue":"9","key":"pone.0249139.ref014","first-page":"865","article-title":"Postvitrectomy diabetic vitreous hemorrhage in proliferative diabetic retinopathy","volume":"17","author":"L Shi","year":"2012","journal-title":"J Res Med Sci"},{"issue":"5","key":"pone.0249139.ref015","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00417-016-3579-4","article-title":"Vitrectomy for complications of proliferative diabetic retinopathy in young adults: clinical features and surgical outcomes","volume":"255","author":"CH Huang","year":"2017","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"8","key":"pone.0249139.ref016","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1136\/bjophthalmol-2017-311344","article-title":"Antivascular endothelial growth factor agents pretreatment before vitrectomy for complicated proliferative diabetic retinopathy: a meta-analysis of randomised controlled trials","volume":"102","author":"XY Zhao","year":"2018","journal-title":"Br J Ophthalmol"},{"key":"pone.0249139.ref017","doi-asserted-by":"crossref","first-page":"16012","DOI":"10.1038\/nrdp.2016.12","article-title":"Diabetic retinopathy","volume":"2","author":"TY Wong","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"pone.0249139.ref018","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s40942-019-0164-0","article-title":"One-year outcomes of 27-gauge versus 25-gauge pars plana vitrectomy for uncomplicated rhegmatogenous retinal detachment repair","volume":"5","author":"G Sborgia","year":"2019","journal-title":"Int J Retina Vitreous"},{"issue":"4","key":"pone.0249139.ref019","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1007\/s10792-017-0625-0","article-title":"Comparative study of 27-gauge and 25-gauge vitrectomy performed as day surgery","volume":"38","author":"R Mori","year":"2018","journal-title":"Int 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