{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T05:50:34Z","timestamp":1774677034735,"version":"3.50.1"},"reference-count":28,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T00:00:00Z","timestamp":1617753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["2R25HL126145"],"award-info":[{"award-number":["2R25HL126145"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Obesity-related cancer (ORC) is associated with higher amounts of body fat, which could increase the risk of developing cardiovascular disease (CVD). A significant factor associated with CVD is metabolic syndrome (MetS), and MetS prevalence differs by race\/ethnicity. The purpose of this study was to compare the prevalence and predictors of ORCs by race\/ethnicity among adults (&gt;18) with MetS.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This was a retrospective, cross-sectional study using data from the 1999\u20132014 National Health and Nutrition Examination Survey (NHANES). A chi-square test was performed to determine differences in ORC prevalence between non-Hispanic White (NHW), non-Hispanic Black (NHB), and Hispanic participants with MetS. A multivariate logistic regression was used to evaluate predictors (race, sex, income, insurance, education, marital status, and smoking status) of ORC among adults with MetS.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Of the 1,554 adults, the prevalence of ORC was 30.6% among NHWs, 51.3% in NHBs, and 54.1% in Hispanics (<jats:italic>p<\/jats:italic> = &lt;0.001). Females were 6.27 times more likely to have an ORC compared to males (95% CI = 4.95\u201314.11). Compared to NHWs, NHBs were 2.1 times more likely to have an ORC (95% CI = 1.40\u20133.38); and Hispanics were 2.5 times more likely (95% CI = 1.39\u20134.77). For every 1-year unit increase in age, the odds of ORC increased by 3% (95% CI = 1.00\u20131.05).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Among NHANES participants with MetS, the prevalence of ORCs was significantly higher in NHBs and Hispanics, females, and older adults with MetS. Future studies, by race\/ethnicity, are warranted on mortality risk of persons with MetS and ORC.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0249188","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T18:36:00Z","timestamp":1617820560000},"page":"e0249188","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence and predictors of obesity-related cancers among racial\/ethnic groups with metabolic 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