{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:28:37Z","timestamp":1760956117025,"version":"3.37.3"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T00:00:00Z","timestamp":1618531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008982","name":"National Science Foundation","doi-asserted-by":"publisher","award":["NSF Award DBI-1300426"],"award-info":[{"award-number":["NSF Award DBI-1300426"]}],"id":[{"id":"10.13039\/501100008982","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The University of Tennessee, Knoxville"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>In Appalachia, La Crosse virus (LACV) is a leading pediatric arbovirus and public health concern for children under 16 years. LACV is transmitted via the bite of an infected <jats:italic>Aedes<\/jats:italic> mosquito. Thus, it is imperative to understand the dynamics of the local vector population in order to assess risk and transmission. Using entomological data collected from Knox County, Tennessee in 2013, we formulate an environmentally-driven system of ordinary differential equations to model mosquito population dynamics over a single season. Further, we include infected compartments to represent LACV transmission within the mosquito population. Findings suggest that the model, with dependence on degree days and accumulated precipitation, can closely describe field data. This model confirms the need to include these environmental variables when planning control strategies.<\/jats:p>","DOI":"10.1371\/journal.pone.0249811","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T17:30:28Z","timestamp":1618594228000},"page":"e0249811","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["La Crosse virus spread within the mosquito population in Knox County, TN"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2350-2041","authenticated-orcid":true,"given":"Cameron","family":"Cook","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annastashia","family":"Blesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0918-5289","authenticated-orcid":true,"given":"Samantha","family":"Brozak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Lenhart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanna","family":"Reed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9966-6491","authenticated-orcid":true,"given":"Cassandra","family":"Urquhart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abelardo","family":"Moncayo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Trout Fryxell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,4,16]]},"reference":[{"issue":"1","key":"pone.0249811.ref001","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0891-5520(20)30389-5","article-title":"Arboviral infections in the United States","volume":"5","author":"T. 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Teng","year":"2000","journal-title":"J Med Entomol"},{"key":"pone.0249811.ref040","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jtbi.2016.09.015","article-title":"A stage structured mosquito model incorporating effects of precipitation and daily temperature fluctuations","volume":"411","author":"X. Wang","year":"2016","journal-title":"Journal of Theoretical Biology"},{"issue":"5","key":"pone.0249811.ref041","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1093\/jme\/tjx077","article-title":"Aedes Aegypti (Diptera: Culicidae) Abundance Model Improved with Relative Humidity and Precipitation-Driven Egg Hatching","volume":"54","author":"Lega Joceline","year":"2017","journal-title":"Journal of Medical Entomology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0249811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T17:31:21Z","timestamp":1618594281000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0249811"}},"subtitle":[],"editor":[{"given":"Abdallah M.","family":"Samy","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,4,16]]},"references-count":41,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4,16]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0249811","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2021,4,16]]}}}