{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:11:23Z","timestamp":1790201483743,"version":"4.1.0"},"reference-count":37,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T00:00:00Z","timestamp":1617840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>To establish successful strategies and increasing the utilization of preventive services, there is a need to explore the extent to which the general female population is aware and use the service for cervical cancer-screening among women infected with HIV in Africa. Available evidences in this regard are controversial and non-conclusive on this potential issue and therefore, we estimated the pooled effect of the proportion of knowledge, attitude and practice of HIV infected African women towards cervical cancer screening to generate evidence for improved prevention strategies.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We applied a systematic review and meta-analysis of studies conducted in Africa and reported the proportion of knowledge, attitude and practice towards cervical cancer screening. We searched electronic databases: PubMed\/Medline, SCOPUS, ScienceDirect, Web of science, Cumulative Index of Nursing and allied Health Sciences (CINAHL) and Google scholar databases to retrieve papers published in English language till August 2020. We used random-effects model to estimate the pooled effect, and funnel plot to assess publication bias. The registration number of this review study protocol is CRD42020210879.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>In this review, we included eight published papers comprising 2,186 participants. The estimated pooled proportion of knowledge of the participants was 43.0% (95%CI:23.0\u201364.0) while the pooled estimates of attitudes and practices were 38.0% (95%CI: 1.0\u201377.0) and 41.0% (95%CI: 4.0\u201377.0), respectively. The proportion of the outcome variables were extremely heterogeneous across the studies with I<jats:sup>2<\/jats:sup>&gt; 98%).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The pooled estimates of knowledge, attitude and practice were lower than other middle income countries calls for further activities to enhance the uptake of the services and establish successful strategies.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0249960","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T20:05:19Z","timestamp":1617912319000},"page":"e0249960","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":25,"title":["Knowledge, attitude and practice of cervical cancer screening among women infected with HIV in Africa: Systematic review and meta-analysis"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2794-8251","authenticated-orcid":true,"given":"Agajie Likie","family":"Bogale","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilahun","family":"Teklehaymanot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jemal","family":"Haidar Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Getnet Mitike","family":"Kassie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,4,8]]},"reference":[{"key":"pone.0249960.ref001","unstructured":"WHO. 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C"},{"key":"pone.0249960.ref004","unstructured":"\u201cHuman Papillomavirus and Related Diseases Report, Ethiopia\", June 2019."},{"key":"pone.0249960.ref005","unstructured":"WHO guidance note: comprehensive cervical cancer prevention and control: a healthier future for girls and women, 2013"},{"key":"pone.0249960.ref006","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/5423130","article-title":"Knowledge, Attitudes, and Practices towards Cervical Cancer and Screening amongst Female Healthcare Professionals: A Cross-Sectional Study","author":"H Heena","year":"2019","journal-title":"Journal of Oncology"},{"issue":"3","key":"pone.0249960.ref007","first-page":"71","article-title":"A Study on the Prevalence and KAP Regarding Cervical Cancer Among Women Attending a Tertiary Care Hospital in Perambalur","volume":"1","author":"T Varadheswari","year":"2015","journal-title":"International Journal of Preventive Medicine Research"},{"key":"pone.0249960.ref008","first-page":"213","article-title":"Knowledge and Concerns about Cancer in Patients with Primary Gynecologic Cancers","volume":"5","author":"Z Eftekhar","year":"2004","journal-title":"Asian Pacific Journal of Cancer Prevention"},{"issue":"2","key":"pone.0249960.ref009","first-page":"30","article-title":"\u201cAwareness of cervical cancer and its prevention among women of reproductive age group (15\u201349 years) in Bishenpur District, Manipur: A cross-sectional study.\u201d","volume":"19","author":"Singh Akoijam Brogen","year":"2020","journal-title":"IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)"},{"issue":"4","key":"pone.0249960.ref010","doi-asserted-by":"crossref","first-page":"124","DOI":"10.4103\/2249-4855.141132","article-title":"\u201cA cross-sectional study on knowledge, attitude, and practice on cervical cancer and screening among female health care providers of Chennai corporation","volume":"2","author":"VV Anantharaman","year":"2012","journal-title":"Journal of Academy of Medical Sciences"},{"key":"pone.0249960.ref011","doi-asserted-by":"crossref","first-page":"967","DOI":"10.3390\/ijerph14090967","article-title":"Assessing Knowledge and Attitudes towards Cervical Cancer Screening among Rural Women in Eastern China","volume":"14","author":"T Liu","year":"2017","journal-title":"Int. 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Health"},{"issue":"123","key":"pone.0249960.ref027","first-page":"1","article-title":"Knowledge and experience of a cohort of HIV-positive and HIV-negative Ghanaian women after undergoing human papillomavirus and cervical cancer screening","volume":"19","author":"A Stuart","year":"2019","journal-title":"BMC Women\u2019s Health"},{"key":"pone.0249960.ref028","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1007\/s13187-017-1229-0","article-title":"Awareness, Knowledge and Attitudes Towards Cervical Cancer Amongst HIV-Positive Women Receiving Care in a Tertiary Hospital in Nigeria","volume":"33","author":"MO Adibe","year":"2018","journal-title":"J Canc Educ"},{"key":"pone.0249960.ref029","doi-asserted-by":"crossref","first-page":"e020343","DOI":"10.1136\/bmjopen-2017-020343","article-title":"Awareness of cervical cancer among women attending an HIV treatment centre: a cross-sectional study from Morocco","volume":"8","author":"E Belglaiaa","year":"2018","journal-title":"BMJ Open"},{"key":"pone.0249960.ref030","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s13187-014-0787-7","article-title":"Cervical Cancer Screening Knowledge and Behavior among Women Attending an Urban HIV Clinic in Western Kenya","volume":"30","author":"JI Rosser","year":"2015","journal-title":"J Canc Educ"},{"issue":"1","key":"pone.0249960.ref031","doi-asserted-by":"crossref","first-page":"7","DOI":"10.4102\/curationis.v37i1.1209","article-title":"\u2018Exploration of knowledge of cervical cancer and cervical cancer screening amongst HIV- positive women\u2019","volume":"37","author":"J.E. 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