{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:59:15Z","timestamp":1787497155596,"version":"build-2736575974"},"reference-count":22,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T00:00:00Z","timestamp":1618358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100008257","name":"Tarbiat Modares University","doi-asserted-by":"crossref","award":["PhD Thesis"],"award-info":[{"award-number":["PhD Thesis"]}],"id":[{"id":"10.13039\/501100008257","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Pasteur Institute of Iran and Centre for Communicable Diseases Control in Ministry of Health","award":["Grant No. 810"],"award-info":[{"award-number":["Grant No. 810"]}]},{"name":"Iranian National Scientific Foundation","award":["INSF; Contracted No.91004716"],"award-info":[{"award-number":["INSF; Contracted No.91004716"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Coxiella burnetii<\/jats:italic>\n                      is the causative agent of Q fever which is a highly infectious zoonotic disease.\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      has become one of the most important causes of abortion in livestock, which can lead to widespread abortions in these animals. There are very limited studies on the prevalence of\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      infection in cases of animal abortion in Iran. The aim of this study was to investigate the occurrence of\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      in ruminant abortion samples in Iran.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Abortion samples from cattle, sheep and goats were collected from different parts of Iran and were tested using Real-time PCR targeting the IS1111 element of\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In this study, 36 samples (24.7%) of the 146 collected samples were positive for\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      . The prevalence of\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      was 21.3% (20 of 94 samples) in sheep samples. Also, 10 of 46 cattle samples (21.7%) were positive. All six goat abortion samples were positive for\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The findings of the study demonstrate that\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      plays an important role in domestic ruminant abortions in Iran, suggesting that more attention should be paid to the role of\n                      <jats:italic>C<\/jats:italic>\n                      .\n                      <jats:italic>burnetii<\/jats:italic>\n                      in domestic animal abortions by veterinary organizations. The risk of transmitting the infection to humans due to abortion of animals should also be considered.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0250116","type":"journal-article","created":{"date-parts":[[2021,4,14]],"date-time":"2021-04-14T17:26:38Z","timestamp":1618421198000},"page":"e0250116","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":24,"title":["Molecular detection of Coxiella burnetii infection in aborted samples of domestic ruminants in Iran"],"prefix":"10.1371","volume":"16","author":[{"given":"Ashraf","family":"Mohabati Mobarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Khalili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehsan","family":"Mostafavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1920-1737","authenticated-orcid":true,"given":"Saber","family":"Esmaeili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,4,14]]},"reference":[{"issue":"1","key":"pone.0250116.ref001","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1128\/CMR.00045-16","article-title":"From Q fever to Coxiella burnetii infection: a paradigm change","volume":"30","author":"C Eldin","year":"2017","journal-title":"Clin Microbiol 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